NO20023385D0 - Etanolopplösning av (-)-cis-2-(2-klorofenyl)-5,7-dihydroksy- 8(4R-(3S-hydroksy-1-metyl)piperidinyl)-4H-1-benzopyran-4-on - Google Patents

Etanolopplösning av (-)-cis-2-(2-klorofenyl)-5,7-dihydroksy- 8(4R-(3S-hydroksy-1-metyl)piperidinyl)-4H-1-benzopyran-4-on

Info

Publication number
NO20023385D0
NO20023385D0 NO20023385A NO20023385A NO20023385D0 NO 20023385 D0 NO20023385 D0 NO 20023385D0 NO 20023385 A NO20023385 A NO 20023385A NO 20023385 A NO20023385 A NO 20023385A NO 20023385 D0 NO20023385 D0 NO 20023385D0
Authority
NO
Norway
Prior art keywords
benzopyran
piperidinyl
chlorophenyl
dihydroxy
cis
Prior art date
Application number
NO20023385A
Other languages
English (en)
Other versions
NO322626B1 (no
NO20023385L (no
Inventor
Kurt M Kesseler
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of NO20023385D0 publication Critical patent/NO20023385D0/no
Publication of NO20023385L publication Critical patent/NO20023385L/no
Publication of NO322626B1 publication Critical patent/NO322626B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO20023385A 2000-01-18 2002-07-12 Hydroklorid-etanol-solvatform av (-)-cis-2-(2-klorfenyl)-5,7-dihydroksy-8[4R-(3S-hydroksy-1-metyl)piperidinyl]-4H-1-benzopyran-4-on, fremgangsmate for fremstilling derav og anvendelse derav ved behandling av cancer. NO322626B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48781500A 2000-01-18 2000-01-18
PCT/US2001/000520 WO2001053294A1 (en) 2000-01-18 2001-01-08 Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one

Publications (3)

Publication Number Publication Date
NO20023385D0 true NO20023385D0 (no) 2002-07-12
NO20023385L NO20023385L (no) 2002-08-27
NO322626B1 NO322626B1 (no) 2006-11-06

Family

ID=23937213

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20023385A NO322626B1 (no) 2000-01-18 2002-07-12 Hydroklorid-etanol-solvatform av (-)-cis-2-(2-klorfenyl)-5,7-dihydroksy-8[4R-(3S-hydroksy-1-metyl)piperidinyl]-4H-1-benzopyran-4-on, fremgangsmate for fremstilling derav og anvendelse derav ved behandling av cancer.

Country Status (26)

Country Link
EP (1) EP1252155B1 (no)
JP (1) JP2003520798A (no)
KR (1) KR100825530B1 (no)
CN (1) CN1395577A (no)
AR (1) AR027226A1 (no)
AT (1) ATE284400T1 (no)
AU (1) AU2001230869A1 (no)
BR (1) BR0107724A (no)
CA (1) CA2397594C (no)
CZ (1) CZ301235B6 (no)
DE (1) DE60107652T2 (no)
DK (1) DK1252155T3 (no)
EA (1) EA005182B1 (no)
ES (1) ES2228800T3 (no)
HU (1) HU225155B1 (no)
IL (2) IL150643A0 (no)
MX (1) MXPA02006965A (no)
NO (1) NO322626B1 (no)
NZ (1) NZ520281A (no)
PL (1) PL201690B1 (no)
PT (1) PT1252155E (no)
SI (1) SI1252155T1 (no)
SK (1) SK287216B6 (no)
TW (1) TWI293072B (no)
WO (1) WO2001053294A1 (no)
ZA (1) ZA200205640B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109803684B (zh) 2016-08-23 2022-08-23 卫材 R&D 管理有限公司 用于治疗肝细胞癌的组合疗法
KR102517650B1 (ko) 2017-03-16 2023-04-05 에자이 알앤드디 매니지먼트 가부시키가이샤 유방암의 치료를 위한 조합물 요법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN164232B (no) * 1986-04-11 1989-02-04 Hoechst India
DE3836676A1 (de) * 1988-10-28 1990-05-03 Hoechst Ag Die verwendung von 4h-1-benzopyran-4-on-derivaten, neue 4h-1-benzopyran-4-on-derivate und diese enthaltende arzneimittel
US5284856A (en) * 1988-10-28 1994-02-08 Hoechst Aktiengesellschaft Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives
US5908934A (en) * 1996-09-26 1999-06-01 Bristol-Myers Squibb Company Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs

Also Published As

Publication number Publication date
MXPA02006965A (es) 2004-09-06
CN1395577A (zh) 2003-02-05
NZ520281A (en) 2004-04-30
SI1252155T1 (en) 2005-06-30
WO2001053294A1 (en) 2001-07-26
KR100825530B1 (ko) 2008-04-25
SK287216B6 (sk) 2010-03-08
EA005182B1 (ru) 2004-12-30
AU2001230869A1 (en) 2001-07-31
KR20020069514A (ko) 2002-09-04
ES2228800T3 (es) 2005-04-16
IL150643A0 (en) 2003-02-12
HU225155B1 (en) 2006-07-28
JP2003520798A (ja) 2003-07-08
BR0107724A (pt) 2002-10-01
EP1252155A1 (en) 2002-10-30
ZA200205640B (en) 2003-11-26
ATE284400T1 (de) 2004-12-15
CA2397594C (en) 2010-03-23
PT1252155E (pt) 2005-04-29
CA2397594A1 (en) 2001-07-26
AR027226A1 (es) 2003-03-19
CZ301235B6 (cs) 2009-12-16
DK1252155T3 (da) 2005-04-04
TWI293072B (en) 2008-02-01
IL150643A (en) 2009-08-03
DE60107652D1 (de) 2005-01-13
EA200200776A1 (ru) 2002-12-26
PL355992A1 (en) 2004-05-31
DE60107652T2 (de) 2005-12-22
PL201690B1 (pl) 2009-04-30
HUP0204297A2 (hu) 2003-04-28
NO322626B1 (no) 2006-11-06
CZ20022467A3 (cs) 2002-10-16
SK10372002A3 (sk) 2002-12-03
HUP0204297A3 (en) 2005-04-28
EP1252155B1 (en) 2004-12-08
NO20023385L (no) 2002-08-27

Similar Documents

Publication Publication Date Title
DK1309593T3 (da) Substituerede pyrazoler
AU2001276048A1 (en) Rapid-melt semi-solid compositions, methods of making same and methods of using same
TR199800608A3 (tr) Propanolamin türevleri, bunlarin üretim usulü.
AU2002211652A1 (en) Method of making an electrode
NO20023662L (no) Nye heterocykliske derivater, fremgangsmåte ved fremstilling og farmasöytiske sammensetninger inneholdende det samme
ATE344273T1 (de) Verfahren zur herstellung von 21-hydroxy-6,19- oxidoprogesteron (21oh-6op)
WO2002046178A3 (en) Benzofuran and benzothiophene derivatives as selective cox-2 inhibitors
NO20023385D0 (no) Etanolopplösning av (-)-cis-2-(2-klorofenyl)-5,7-dihydroksy- 8(4R-(3S-hydroksy-1-metyl)piperidinyl)-4H-1-benzopyran-4-on
PL345236A1 (en) Novel benzenesulphonamide compounds, method of obtaining them and pharmacological compositions containing such compounds
DE60138370D1 (de) Verdaulicher kaugummi
PL351301A1 (en) Novel inhibitors of metaloprotease, methods of obtaining them and pharmacological composition containing such inhibitors
NO20024657L (no) Bössing innbefattende et terminalavlöp, og fremgangsmÕte for produksjon av bössing
NO20023386D0 (no) Pseudopolymorf av (-)-cis-2-(2-klorfenyl)-5,7-dihydroksy-8(4R- (3S-hydroksy-1-metyl)piperidinyl)-4H-1-benzopyran-4-on
TR199802200A3 (tr) Sülfonamid sübstitüe edilmis benzopiran türevleri, üretilme yöntemi.
DE50205310D1 (de) Isoflavonkonzentrate sowie verfahren zu ihrer herstellung
PL351317A1 (en) Novel derivatives of morpholine, method of obtaining them and pharmacological agent containing such derivatives
AU4834001A (en) Method for producing benzo annelated heterocycles
BR0111221A (pt) Condensados glioxal-fenólicos com fluorescência intensificada
AR027225A1 (es) Pseudopolimorfo de (-)-cis-2-(2-clorofenil)-5,7-dihidroxi-8[4r(3s-hidroxi-1-metil)piperdinil]-4h-1-benzopiran-4-ona
AU2001265700A1 (en) Method of sentence analysis
UA34042A (uk) Спосіб моделювання гідроуретеронефрозу

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees