PL337397A1 - Novel derivatives of 4-{3-[4-(imidazol-1-yl)phenylsuphanyl]phenyl}tetrahydropyrane-4-carboxamide and method of obtaining them as well as novel intermediate compounds - Google Patents

Novel derivatives of 4-{3-[4-(imidazol-1-yl)phenylsuphanyl]phenyl}tetrahydropyrane-4-carboxamide and method of obtaining them as well as novel intermediate compounds

Info

Publication number
PL337397A1
PL337397A1 PL99337397A PL33739799A PL337397A1 PL 337397 A1 PL337397 A1 PL 337397A1 PL 99337397 A PL99337397 A PL 99337397A PL 33739799 A PL33739799 A PL 33739799A PL 337397 A1 PL337397 A1 PL 337397A1
Authority
PL
Poland
Prior art keywords
novel
phenylsuphanyl
tetrahydropyrane
imidazol
carboxamide
Prior art date
Application number
PL99337397A
Other languages
English (en)
Inventor
Chiu Charles Kwok-Fung
Ravi Mysore Shanker
Allen Douglas John Meldrum
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PL337397A1 publication Critical patent/PL337397A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
PL99337397A 1998-12-22 1999-12-22 Novel derivatives of 4-{3-[4-(imidazol-1-yl)phenylsuphanyl]phenyl}tetrahydropyrane-4-carboxamide and method of obtaining them as well as novel intermediate compounds PL337397A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11322198P 1998-12-22 1998-12-22

Publications (1)

Publication Number Publication Date
PL337397A1 true PL337397A1 (en) 2000-07-03

Family

ID=22348241

Family Applications (1)

Application Number Title Priority Date Filing Date
PL99337397A PL337397A1 (en) 1998-12-22 1999-12-22 Novel derivatives of 4-{3-[4-(imidazol-1-yl)phenylsuphanyl]phenyl}tetrahydropyrane-4-carboxamide and method of obtaining them as well as novel intermediate compounds

Country Status (22)

Country Link
US (1) US6194585B1 (enExample)
EP (1) EP1029865B1 (enExample)
JP (2) JP3468729B2 (enExample)
KR (1) KR100362789B1 (enExample)
CN (1) CN1258675A (enExample)
AR (1) AR019497A3 (enExample)
AT (1) ATE265460T1 (enExample)
AU (1) AU6539199A (enExample)
BR (1) BR9905918A (enExample)
CA (1) CA2289422A1 (enExample)
CZ (1) CZ453699A3 (enExample)
DE (1) DE69916778D1 (enExample)
HU (1) HUP9904282A3 (enExample)
ID (1) ID24014A (enExample)
IL (1) IL132897A0 (enExample)
IN (1) IN187165B (enExample)
PL (1) PL337397A1 (enExample)
RU (1) RU2181722C2 (enExample)
TR (1) TR199903204A2 (enExample)
TW (1) TW455586B (enExample)
YU (1) YU59399A (enExample)
ZA (1) ZA997113B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4569187B2 (ja) * 2004-06-17 2010-10-27 宇部興産株式会社 4−シアノテトラヒドロピランの製法
EP1834953A1 (en) * 2006-03-14 2007-09-19 Ranbaxy Laboratories Limited Tetrahydropyrane derivatives as 5-lipoxygenase inhibitors
JP4469924B2 (ja) * 2006-11-27 2010-06-02 ファイザー・プロダクツ・インク ピラゾール類似体
CN107233337A (zh) 2009-04-29 2017-10-10 阿马里纳药物爱尔兰有限公司 含有epa和心血管剂的药物组合物以及使用其的方法
EP4081199A4 (en) * 2019-12-23 2024-01-17 SRI International LIPOXYGENASE INHIBITORS

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
US5212198A (en) * 1990-05-10 1993-05-18 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof
EP0462830B1 (en) * 1990-06-21 1995-10-18 Zeneca Limited Cyclic ether derivatives
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives
IE914005A1 (en) * 1990-12-14 1992-06-17 Zeneca Ltd Novel intermediates
EP0505122A1 (en) * 1991-03-21 1992-09-23 Zeneca Limited Alpha, alpha-dialkylbenzyl derivatives
EP0540165A1 (en) * 1991-10-03 1993-05-05 Zeneca Limited Alkanoic acid derivatives
PL175987B1 (pl) * 1993-06-14 1999-03-31 Pfizer Nowe imidazolowe inhibitory lipoksygenazy
US5883106A (en) * 1994-10-18 1999-03-16 Pfizer Inc. 5-lipoxygenase inhibitors
SK281577B6 (sk) * 1994-10-18 2001-05-10 Pfizer Inc. Heterocyklické zlúčeniny a farmaceutický prostriedok na ich báze

Also Published As

Publication number Publication date
DE69916778D1 (de) 2004-06-03
IL132897A0 (en) 2001-03-19
AU6539199A (en) 2000-06-29
ID24014A (id) 2000-06-22
IN187165B (enExample) 2002-02-23
ZA997113B (en) 2001-05-15
HU9904282D0 (en) 2000-01-28
EP1029865A3 (en) 2000-11-08
TW455586B (en) 2001-09-21
TR199903204A2 (xx) 2000-07-21
MX9912076A (enExample) 2000-04-30
JP2004002415A (ja) 2004-01-08
CA2289422A1 (en) 2000-06-22
ATE265460T1 (de) 2004-05-15
JP2000191654A (ja) 2000-07-11
EP1029865A2 (en) 2000-08-23
EP1029865B1 (en) 2004-04-28
KR100362789B1 (ko) 2002-11-30
HUP9904282A3 (en) 2001-04-28
US6194585B1 (en) 2001-02-27
RU2181722C2 (ru) 2002-04-27
YU59399A (sh) 2002-11-15
KR20000052537A (ko) 2000-08-25
CN1258675A (zh) 2000-07-05
BR9905918A (pt) 2000-09-26
HUP9904282A2 (hu) 2000-12-28
CZ453699A3 (cs) 2000-07-12
AR019497A3 (es) 2002-02-20
JP3468729B2 (ja) 2003-11-17

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