PL3087179T3 - Polipeptydy fuzyjne związane z omega-hydroksylazą o ulepszonych właściwościach - Google Patents
Polipeptydy fuzyjne związane z omega-hydroksylazą o ulepszonych właściwościachInfo
- Publication number
- PL3087179T3 PL3087179T3 PL15732504T PL15732504T PL3087179T3 PL 3087179 T3 PL3087179 T3 PL 3087179T3 PL 15732504 T PL15732504 T PL 15732504T PL 15732504 T PL15732504 T PL 15732504T PL 3087179 T3 PL3087179 T3 PL 3087179T3
- Authority
- PL
- Poland
- Prior art keywords
- hydroxylase
- omega
- improved properties
- fusion polypeptides
- related fusion
- Prior art date
Links
- 102000005297 Cytochrome P-450 CYP4A Human genes 0.000 title 1
- 108010081498 Cytochrome P-450 CYP4A Proteins 0.000 title 1
- 230000004927 fusion Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/15—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen (1.14.15)
- C12Y114/15003—Alkane 1-monooxygenase (1.14.15.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01005—Lysophospholipase (3.1.1.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/02—Thioester hydrolases (3.1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/02—Thioester hydrolases (3.1.2)
- C12Y301/02014—Oleoyl-[acyl-carrier-protein] hydrolase (3.1.2.14), i.e. ACP-thioesterase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462012970P | 2014-06-16 | 2014-06-16 | |
| EP15732504.4A EP3087179B1 (en) | 2014-06-16 | 2015-06-16 | Omega-hydroxylase-related fusion polypeptides with improved properties |
| PCT/US2015/036078 WO2015195697A1 (en) | 2014-06-16 | 2015-06-16 | Omega-hydroxylase-related fusion polypeptides with improved properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3087179T3 true PL3087179T3 (pl) | 2020-09-21 |
Family
ID=53491691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15732504T PL3087179T3 (pl) | 2014-06-16 | 2015-06-16 | Polipeptydy fuzyjne związane z omega-hydroksylazą o ulepszonych właściwościach |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11441130B2 (pl) |
| EP (2) | EP3690035A3 (pl) |
| JP (3) | JP6826435B2 (pl) |
| KR (2) | KR102439589B1 (pl) |
| CN (3) | CN106604990B (pl) |
| AU (2) | AU2015277261B2 (pl) |
| BR (1) | BR112016029235B1 (pl) |
| CA (1) | CA2951925A1 (pl) |
| ES (1) | ES2803560T3 (pl) |
| MX (1) | MX372803B (pl) |
| MY (2) | MY198268A (pl) |
| PL (1) | PL3087179T3 (pl) |
| SI (1) | SI3087179T1 (pl) |
| WO (1) | WO2015195697A1 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7004500B2 (ja) | 2013-06-14 | 2022-02-04 | ジェノマティカ， インコーポレイテッド | ω－ヒドロキシル化脂肪酸誘導体を生産する方法 |
| US11441130B2 (en) * | 2014-06-16 | 2022-09-13 | Genomatica, Inc. | Omega-hydroxylase-related fusion polypeptides with improved properties |
| WO2017101987A1 (en) | 2015-12-15 | 2017-06-22 | REG Life Sciences, LLC | Omega-hydroxylase-related fusion polypeptide variants with improved properties |
| JP7705243B2 (ja) | 2017-04-03 | 2025-07-09 | ジェノマティカ， インコーポレイテッド | 中鎖脂肪酸誘導体の生産のための改良された活性を有するチオエステラーゼ変種 |
| CN112673016B (zh) | 2018-08-31 | 2025-08-05 | 基因组股份公司 | 用于改善的木糖利用或改善的葡萄糖和木糖共利用的xylr突变体 |
| CN119391659B (zh) * | 2024-10-30 | 2025-10-10 | 天津凯莱英生物科技有限公司 | 多肽连接酶突变体及多肽的制备方法 |
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| US5000000A (en) | 1988-08-31 | 1991-03-19 | University Of Florida | Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes |
| US5028539A (en) | 1988-08-31 | 1991-07-02 | The University Of Florida | Ethanol production using engineered mutant E. coli |
| US5482846A (en) | 1988-08-31 | 1996-01-09 | University Of Florida | Ethanol production in Gram-positive microbes |
| US5424202A (en) | 1988-08-31 | 1995-06-13 | The University Of Florida | Ethanol production by recombinant hosts |
| AU7791991A (en) | 1990-04-24 | 1991-11-11 | Stratagene | Methods for phenotype creation from multiple gene populations |
| US5602030A (en) | 1994-03-28 | 1997-02-11 | University Of Florida Research Foundation | Recombinant glucose uptake system |
| US6428767B1 (en) | 1995-05-12 | 2002-08-06 | E. I. Du Pont De Nemours And Company | Method for identifying the source of carbon in 1,3-propanediol |
| US5939250A (en) | 1995-12-07 | 1999-08-17 | Diversa Corporation | Production of enzymes having desired activities by mutagenesis |
| US5965408A (en) | 1996-07-09 | 1999-10-12 | Diversa Corporation | Method of DNA reassembly by interrupting synthesis |
| AU2003241300B2 (en) | 2002-04-29 | 2008-10-16 | Dow Global Technologies Inc. | Integrated chemical processes for industrial utilization of seed oils |
| US20080220419A1 (en) | 2004-11-10 | 2008-09-11 | Marine Biotechnology Institute Co., Ltd. | Method of Isolating P450 Gene |
| EP2157170B1 (en) | 2006-05-19 | 2014-01-15 | LS9, Inc. | Production of fatty acids and derivatives thereof |
| US8110670B2 (en) | 2006-05-19 | 2012-02-07 | Ls9, Inc. | Enhanced production of fatty acid derivatives |
| US20100242345A1 (en) | 2006-05-19 | 2010-09-30 | LS9, Inc | Production of fatty acids & derivatives thereof |
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| US11441130B2 (en) | 2014-06-16 | 2022-09-13 | Genomatica, Inc. | Omega-hydroxylase-related fusion polypeptides with improved properties |
| WO2017101987A1 (en) | 2015-12-15 | 2017-06-22 | REG Life Sciences, LLC | Omega-hydroxylase-related fusion polypeptide variants with improved properties |
-
2015
- 2015-06-16 US US15/319,272 patent/US11441130B2/en active Active
- 2015-06-16 CA CA2951925A patent/CA2951925A1/en active Pending
- 2015-06-16 MY MYPI2016002190A patent/MY198268A/en unknown
- 2015-06-16 MY MYPI2022002249A patent/MY207981A/en unknown
- 2015-06-16 PL PL15732504T patent/PL3087179T3/pl unknown
- 2015-06-16 WO PCT/US2015/036078 patent/WO2015195697A1/en not_active Ceased
- 2015-06-16 BR BR112016029235-9A patent/BR112016029235B1/pt active IP Right Grant
- 2015-06-16 CN CN201580032792.3A patent/CN106604990B/zh active Active
- 2015-06-16 ES ES15732504T patent/ES2803560T3/es active Active
- 2015-06-16 EP EP20160184.6A patent/EP3690035A3/en active Pending
- 2015-06-16 EP EP15732504.4A patent/EP3087179B1/en active Active
- 2015-06-16 SI SI201531270T patent/SI3087179T1/sl unknown
- 2015-06-16 MX MX2016016565A patent/MX372803B/es active IP Right Grant
- 2015-06-16 JP JP2016573541A patent/JP6826435B2/ja active Active
- 2015-06-16 AU AU2015277261A patent/AU2015277261B2/en not_active Ceased
- 2015-08-13 CN CN202511366259.2A patent/CN121203035A/zh active Pending
- 2015-08-13 KR KR1020177001306A patent/KR102439589B1/ko active Active
- 2015-08-13 CN CN202210284305.4A patent/CN114605558A/zh active Pending
- 2015-08-13 KR KR1020227029909A patent/KR102663049B1/ko active Active
-
2019
- 2019-10-23 US US16/661,667 patent/US11421206B2/en active Active
- 2019-11-15 JP JP2019206602A patent/JP2020036610A/ja active Pending
-
2021
- 2021-04-12 AU AU2021202194A patent/AU2021202194A1/en not_active Abandoned
- 2021-11-18 JP JP2021187660A patent/JP7564800B2/ja active Active
-
2022
- 2022-08-08 US US17/818,038 patent/US20230167419A1/en active Pending
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