PL3013350T3 - Zastosowanie cząsteczek hamujących semaforynę-4d w kombinacji z terapią modulującą odporność w celu hamowania wzrostu i przerzutów guza - Google Patents
Zastosowanie cząsteczek hamujących semaforynę-4d w kombinacji z terapią modulującą odporność w celu hamowania wzrostu i przerzutów guzaInfo
- Publication number
- PL3013350T3 PL3013350T3 PL14818498T PL14818498T PL3013350T3 PL 3013350 T3 PL3013350 T3 PL 3013350T3 PL 14818498 T PL14818498 T PL 14818498T PL 14818498 T PL14818498 T PL 14818498T PL 3013350 T3 PL3013350 T3 PL 3013350T3
- Authority
- PL
- Poland
- Prior art keywords
- semaphorin
- metastases
- combination
- tumor growth
- inhibit tumor
- Prior art date
Links
- 108010056102 CD100 antigen Proteins 0.000 title 1
- 206010027476 Metastases Diseases 0.000 title 1
- 102100027744 Semaphorin-4D Human genes 0.000 title 1
- 230000002519 immonomodulatory effect Effects 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 230000004614 tumor growth Effects 0.000 title 1
Classifications
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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- A61K38/19—Cytokines; Lymphokines; Interferons
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
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- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- Developmental Biology & Embryology (AREA)
- Virology (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361839170P | 2013-06-25 | 2013-06-25 | |
US201361874241P | 2013-09-05 | 2013-09-05 | |
US201361884771P | 2013-09-30 | 2013-09-30 | |
US201361907845P | 2013-11-22 | 2013-11-22 | |
PCT/US2014/043466 WO2014209802A1 (en) | 2013-06-25 | 2014-06-20 | Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases |
EP14818498.9A EP3013350B1 (en) | 2013-06-25 | 2014-06-20 | Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3013350T3 true PL3013350T3 (pl) | 2020-06-15 |
Family
ID=52142579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL14818498T PL3013350T3 (pl) | 2013-06-25 | 2014-06-20 | Zastosowanie cząsteczek hamujących semaforynę-4d w kombinacji z terapią modulującą odporność w celu hamowania wzrostu i przerzutów guza |
Country Status (18)
Country | Link |
---|---|
US (5) | US9243068B2 (ko) |
EP (2) | EP3013350B1 (ko) |
JP (3) | JP6611709B2 (ko) |
KR (2) | KR20210104166A (ko) |
CN (1) | CN105492016A (ko) |
AU (2) | AU2014302812B2 (ko) |
BR (1) | BR112015032690B1 (ko) |
CA (2) | CA2916245C (ko) |
DK (1) | DK3013350T3 (ko) |
EA (1) | EA036591B1 (ko) |
ES (1) | ES2782834T3 (ko) |
IL (1) | IL243301B (ko) |
MX (1) | MX2015017485A (ko) |
NZ (1) | NZ631015A (ko) |
PL (1) | PL3013350T3 (ko) |
PT (1) | PT3013350T (ko) |
SG (2) | SG10201902380SA (ko) |
WO (1) | WO2014209802A1 (ko) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2010245668B2 (en) | 2009-05-08 | 2016-07-14 | Vaccinex, Inc. | Anti-CD100 antibodies and methods for using the same |
AU2012322721B2 (en) | 2011-10-11 | 2016-05-05 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules for modulation of blood brain barrier permeability |
US9090709B2 (en) | 2012-03-28 | 2015-07-28 | Vaccinex, Inc. | Anti-SEMA4D antibodies and epitopes |
US9708601B2 (en) | 2012-04-26 | 2017-07-18 | Vaccinex, Inc. | Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus |
US10494440B2 (en) | 2012-05-11 | 2019-12-03 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules to promote neurogenesis following stroke |
DK3013350T3 (da) | 2013-06-25 | 2020-04-14 | Vaccinex Inc | Anvendelse af semaphorin-4D-hæmmende molekyler i kombination med en immunmodulerende terapi for at hæmme tumorvækst og metastaser |
NZ630881A (en) | 2013-10-10 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treatment of atherosclerosis |
NZ630892A (en) | 2013-10-21 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treating neurodegenerative disorders |
WO2015167616A1 (en) * | 2014-05-02 | 2015-11-05 | Nitor Therapeutics | Guanosine as an immunepotentiator mediated through toll receptors |
US10973843B2 (en) | 2016-01-27 | 2021-04-13 | University Of Maryland, Baltimore | Method for monitoring cancer and for regulation of semaphorin 4D to improve cancer immunotherapy regimens |
EP3213768A1 (en) | 2016-03-01 | 2017-09-06 | LODOCO CLINICAL Kft | Combination of low dose immune checkpoint blockade with high dose il-2 for treating metastatic cancer |
KR102403660B1 (ko) * | 2016-04-18 | 2022-05-30 | 파론 파머수티컬스 오와이 | CLEVER-1, TNF-α 및 HLA-DR 결합제를 사용하는 면역 활성화의 진단 |
KR102558637B1 (ko) | 2016-04-22 | 2023-07-24 | 백시넥스 인코포레이티드 | 폭스바이러스 세포외 피막형 비리온 상에서의 내재막 단백질 디스플레이 |
EP3473262A4 (en) * | 2016-06-16 | 2020-03-18 | The University Of Tokyo | PLEXIN BINDING REGULATOR |
IL264343B2 (en) | 2016-08-02 | 2024-05-01 | Vaccinex Inc | Improved methods for generating polynucleotide libraries in cowpox/eukaryotic cells |
USD889258S1 (en) * | 2016-08-04 | 2020-07-07 | Carolin McKie | Beverage container identification marker kit |
CN110300598A (zh) * | 2016-09-16 | 2019-10-01 | 布里格姆妇女医院有限公司 | Klrg1消耗治疗 |
KR102661905B1 (ko) * | 2016-10-12 | 2024-04-29 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | Tusc2 면역요법을 위한 방법 및 조성물 |
AU2018219226A1 (en) | 2017-02-07 | 2019-08-15 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
DK3600419T5 (en) * | 2017-03-20 | 2024-05-27 | Vaccinex Inc | Treatment of cancer with a semaphorin-4d antibody in combination with an epigenetic modulating agent |
EP3612210A4 (en) | 2017-04-19 | 2021-01-27 | Board Of Regents, The University Of Texas System | IMMUNE CELLS EXPRESSING MODIFIED ANTIGEN RECEPTORS |
US11427634B2 (en) | 2017-05-05 | 2022-08-30 | Vaccinex, Inc. | Human anti-semaphorin 4D antibody |
CA3089319A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
EP3693380A1 (en) * | 2019-02-11 | 2020-08-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Dual inhibition of plexin-b1 and plexin-b2 |
AU2020244862B2 (en) * | 2019-03-28 | 2023-01-05 | Merck Kgaa | Semaphorin-4D antagonists for use in cancer therapy |
EP3986446A1 (en) | 2019-06-21 | 2022-04-27 | Vaccinex, Inc. | Combination therapy with semaphorin-4d blockade (sema4d) and dc1 therapy |
CA3152371A1 (en) | 2019-08-01 | 2021-02-04 | Vaccinex, Inc. | Combined inhibition of semaphorin-4d and tgf.beta. and compositions therefor |
CN111158663B (zh) * | 2019-12-26 | 2021-07-02 | 深圳逻辑汇科技有限公司 | 用于处理程序代码中的变量的引用的方法和系统 |
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