PL2900279T3 - Antagonisty grpr do wykrywania, diagnostyki i leczenia raka grpr-pozytywnego - Google Patents

Antagonisty grpr do wykrywania, diagnostyki i leczenia raka grpr-pozytywnego

Info

Publication number
PL2900279T3
PL2900279T3 PL13815181T PL13815181T PL2900279T3 PL 2900279 T3 PL2900279 T3 PL 2900279T3 PL 13815181 T PL13815181 T PL 13815181T PL 13815181 T PL13815181 T PL 13815181T PL 2900279 T3 PL2900279 T3 PL 2900279T3
Authority
PL
Poland
Prior art keywords
grpr
antagonists
diagnosis
detection
treatment
Prior art date
Application number
PL13815181T
Other languages
English (en)
Polish (pl)
Inventor
Theodosia MAINA-NOCK
Berthold Artur NOCK
Marion DE JONG HENDRIKS
Original Assignee
Advanced Accelerator Applications Usa, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Accelerator Applications Usa, Inc. filed Critical Advanced Accelerator Applications Usa, Inc.
Publication of PL2900279T3 publication Critical patent/PL2900279T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008Peptides; Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PL13815181T 2012-09-25 2013-09-25 Antagonisty grpr do wykrywania, diagnostyki i leczenia raka grpr-pozytywnego PL2900279T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261705513P 2012-09-25 2012-09-25
EP13815181.6A EP2900279B1 (en) 2012-09-25 2013-09-25 Grpr-antagonists for detection, diagnosis and treatment of grpr-positive cancer
PCT/US2013/061712 WO2014052471A1 (en) 2012-09-25 2013-09-25 Grpr-antagonists for detection, diagnosis and treatment of grpr-positive cancer

Publications (1)

Publication Number Publication Date
PL2900279T3 true PL2900279T3 (pl) 2020-05-18

Family

ID=49887190

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13815181T PL2900279T3 (pl) 2012-09-25 2013-09-25 Antagonisty grpr do wykrywania, diagnostyki i leczenia raka grpr-pozytywnego

Country Status (19)

Country Link
US (7) US9839703B2 (enExample)
EP (2) EP2900279B1 (enExample)
JP (4) JP6562838B2 (enExample)
KR (2) KR102314293B1 (enExample)
AU (4) AU2013323596C1 (enExample)
BR (1) BR112015006453B1 (enExample)
CA (2) CA2886068C (enExample)
DK (1) DK2900279T3 (enExample)
ES (1) ES2745635T3 (enExample)
HR (1) HRP20191620T1 (enExample)
HU (1) HUE045724T2 (enExample)
IL (4) IL276300B2 (enExample)
LT (1) LT2900279T (enExample)
MX (1) MX362675B (enExample)
PL (1) PL2900279T3 (enExample)
PT (1) PT2900279T (enExample)
RU (1) RU2693465C9 (enExample)
SI (1) SI2900279T1 (enExample)
WO (1) WO2014052471A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2729183B1 (en) * 2011-07-08 2018-09-05 Advanced Accelerator Applications USA, Inc. Enhanced in vivo targeting of radiolabelled peptides with the means of enzyme inhibitors
JP6562838B2 (ja) * 2012-09-25 2019-08-21 アドヴァンスド アクセレレーター アプリケーションズ ユー・エス・エイ インコーポレイテッドAdvanced Accelerator Applications USA, Inc. Grpr陽性ガンの診断画像及び治療適用のための放射標識したgrprアンタゴニスト
EP3015462A1 (en) * 2014-10-29 2016-05-04 OctreoPharm Schiences GmbH Enantiopure chelating agents for chelator coupled pharmaceuticals, corresponding preparation method thereof and chelator coupled pharmaceuticals
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
WO2018048882A1 (en) 2016-09-06 2018-03-15 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
WO2018096082A1 (en) 2016-11-28 2018-05-31 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
DK3568205T3 (da) 2017-01-12 2023-10-09 Radiomedix Inc Behandling af cancerceller, der overeksprimerer somatostatinreceptorer ved at anvende radioisotop-chelaterede ocreotid-derivater
WO2020074691A1 (en) * 2018-10-12 2020-04-16 Advanced Accelerator Applications International Sa Pharmaceutical composition comprising a radiolabeled gprp antagonist and a surfactant
CA3118743A1 (en) * 2018-11-13 2021-04-15 Provincial Health Services Authority Radiolabeled bombesin-derived compounds for in vivo imaging of gastrin-releasing peptide receptor (grpr) and treatment of grpr-related disorders
AU2019382881B2 (en) 2018-11-23 2025-06-12 Bayer Aktiengesellschaft Formulation of contrast media and process of preparation thereof
AU2020349002B2 (en) * 2019-09-16 2024-05-02 Novartis Ag Stable, concentrated radiopharmaceutical composition
TWI878344B (zh) * 2019-09-17 2025-04-01 瑞士商諾華公司 放射性標記grpr拮抗劑之方法及其套組
CA3155462A1 (en) * 2019-09-24 2021-04-01 Novartis Ag Radiolabelled grpr-antagonist for use as theragnostic
IL293008A (en) * 2019-12-19 2022-07-01 Univ Muenchen Tech Modified peptides that are antagonistic to grpr for cancer imaging and therapy
CA3246188A1 (en) 2022-03-25 2023-09-28 The University Of British Columbia Radiolabeled compounds for in vivo imaging of the gastrin-releasing peptide (GRPR) receptor and treatment of GRPR-related disorders

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019647A (en) * 1988-05-24 1991-05-28 Merck & Co., Inc. Gastrin releasing peptide antagonist
US4943561A (en) 1988-11-28 1990-07-24 Merck & Co., Inc. Gastrin releasing peptide antagonist
US5028692A (en) * 1989-04-25 1991-07-02 Merck & Co., Inc. Gastrin releasing peptide antagonist
IL96216A0 (en) 1989-11-06 1991-08-16 Erba Carlo Spa Peptide derivatives,their preparation and pharmaceutical compositions containing them
JPH07505865A (ja) 1992-02-07 1995-06-29 メレルダウファーマスーティカルズ インコーポレイテッド ボンベシンのフェニルアラニン類似体類
US5620955A (en) 1993-06-18 1997-04-15 Peptide Technologies Corporation Bombesin receptor antagonists and uses thereof
AU1172599A (en) 1997-11-18 1999-06-07 Chugai Seiyaku Kabushiki Kaisha Compounds with antitumor activity
CA2526556C (en) 2003-07-24 2012-09-25 Bracco Imaging S.P.A. Stable radiopharmaceutical compositions and methods for their preparation
EP2100900A1 (en) 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
IN2013MN01188A (enExample) 2010-11-22 2015-07-10 Piramal Imaging Sa
EP2729183B1 (en) * 2011-07-08 2018-09-05 Advanced Accelerator Applications USA, Inc. Enhanced in vivo targeting of radiolabelled peptides with the means of enzyme inhibitors
JP6562838B2 (ja) 2012-09-25 2019-08-21 アドヴァンスド アクセレレーター アプリケーションズ ユー・エス・エイ インコーポレイテッドAdvanced Accelerator Applications USA, Inc. Grpr陽性ガンの診断画像及び治療適用のための放射標識したgrprアンタゴニスト

Also Published As

Publication number Publication date
AU2018204513B2 (en) 2019-05-23
CA2886068C (en) 2021-06-22
IL276300A (en) 2020-09-30
JP6562838B2 (ja) 2019-08-21
AU2019216714B2 (en) 2021-04-08
SI2900279T1 (sl) 2019-12-31
JP7358430B2 (ja) 2023-10-10
US20180133349A1 (en) 2018-05-17
ES2745635T3 (es) 2020-03-03
RU2693465C9 (ru) 2020-08-14
AU2021201914A1 (en) 2021-04-29
IL312551B1 (en) 2025-08-01
MX2015003772A (es) 2015-11-09
EP2900279A1 (en) 2015-08-05
US11083805B2 (en) 2021-08-10
KR20200139846A (ko) 2020-12-14
US20220008568A1 (en) 2022-01-13
AU2019216714A1 (en) 2019-09-05
AU2018204513A1 (en) 2018-07-12
JP2015533119A (ja) 2015-11-19
AU2018204513C1 (en) 2020-10-15
IL312551B2 (en) 2025-12-01
DK2900279T3 (da) 2019-09-30
AU2013323596B2 (en) 2018-03-22
US20240366812A1 (en) 2024-11-07
CA3114832A1 (en) 2014-04-03
KR20150090886A (ko) 2015-08-06
KR102190005B1 (ko) 2020-12-15
IL276300B2 (en) 2024-10-01
US9839703B2 (en) 2017-12-12
HUE045724T2 (hu) 2020-01-28
JP2019167365A (ja) 2019-10-03
IL237844B (en) 2018-01-31
EP3536347A1 (en) 2019-09-11
US20210346528A1 (en) 2021-11-11
PT2900279T (pt) 2019-10-14
US20150265732A1 (en) 2015-09-24
RU2015115529A (ru) 2016-11-20
JP2023126440A (ja) 2023-09-07
WO2014052471A1 (en) 2014-04-03
CA2886068A1 (en) 2014-04-03
IL276300B1 (en) 2024-06-01
AU2021201914B2 (en) 2024-09-05
US20200009276A1 (en) 2020-01-09
US20210346529A1 (en) 2021-11-11
AU2013323596A1 (en) 2015-04-02
US12064490B2 (en) 2024-08-20
IL256649B (en) 2020-08-31
HRP20191620T1 (hr) 2019-12-13
IL312551A (en) 2024-07-01
JP6997135B2 (ja) 2022-02-04
RU2693465C2 (ru) 2019-07-03
BR112015006453A2 (enExample) 2017-09-05
MX362675B (es) 2019-01-30
AU2013323596C1 (en) 2020-10-15
LT2900279T (lt) 2019-11-11
EP2900279B1 (en) 2019-08-14
KR102314293B1 (ko) 2021-10-19
US12064491B2 (en) 2024-08-20
JP2021191800A (ja) 2021-12-16
JP7534498B2 (ja) 2024-08-14
US12064489B2 (en) 2024-08-20
IL256649A (en) 2018-02-28
RU2019119378A (ru) 2020-10-23
BR112015006453B1 (pt) 2023-10-17

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