PL2873417T3 - Induktor tolerancji immunologicznej - Google Patents

Induktor tolerancji immunologicznej

Info

Publication number
PL2873417T3
PL2873417T3 PL13816500T PL13816500T PL2873417T3 PL 2873417 T3 PL2873417 T3 PL 2873417T3 PL 13816500 T PL13816500 T PL 13816500T PL 13816500 T PL13816500 T PL 13816500T PL 2873417 T3 PL2873417 T3 PL 2873417T3
Authority
PL
Poland
Prior art keywords
immune tolerance
tolerance inducer
inducer
immune
tolerance
Prior art date
Application number
PL13816500T
Other languages
English (en)
Inventor
Tohru Tanaka
Motowo Nakajima
Fuminori Abe
Naomi HAGA
Kiwamu Takahashi
Hidenori Ito
Ko Rii
Original Assignee
Sbi Pharmaceuticals Co., Ltd.
National Center For Child Health And Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sbi Pharmaceuticals Co., Ltd., National Center For Child Health And Development filed Critical Sbi Pharmaceuticals Co., Ltd.
Publication of PL2873417T3 publication Critical patent/PL2873417T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • C12N5/064—Immunosuppressive dendritic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/05—Adjuvants
    • C12N2501/052—Lipopolysaccharides [LPS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2304—Interleukin-4 (IL-4)
PL13816500T 2012-07-13 2013-07-03 Induktor tolerancji immunologicznej PL2873417T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012157374 2012-07-13
EP13816500.6A EP2873417B1 (en) 2012-07-13 2013-07-03 Immune tolerance inducer
PCT/JP2013/004130 WO2014010206A1 (ja) 2012-07-13 2013-07-03 免疫寛容誘導剤

Publications (1)

Publication Number Publication Date
PL2873417T3 true PL2873417T3 (pl) 2019-09-30

Family

ID=49915689

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13816500T PL2873417T3 (pl) 2012-07-13 2013-07-03 Induktor tolerancji immunologicznej

Country Status (9)

Country Link
US (1) US9399029B2 (pl)
EP (1) EP2873417B1 (pl)
JP (1) JP5904518B2 (pl)
CN (2) CN106474098B (pl)
HK (2) HK1204285A1 (pl)
HU (1) HUE043511T2 (pl)
PL (1) PL2873417T3 (pl)
TW (1) TWI619493B (pl)
WO (1) WO2014010206A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2767278B1 (en) * 2011-10-12 2019-11-06 SBI Pharmaceuticals Co., Ltd. Enhancer of survival of transplanted organ
CN104487067B (zh) * 2012-07-19 2017-09-01 思佰益药业股份有限公司 流行性感冒病毒感染症的预防·治疗剂
CA3088710C (en) 2018-01-18 2023-12-12 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Langerin+ cell targeting
CN113181153B (zh) * 2021-05-31 2023-03-31 北京大学人民医院 柠檬酸在制备预防和/或治疗自身免疫病的药物中的应用
WO2023167066A1 (ja) * 2022-03-01 2023-09-07 国立研究開発法人国立成育医療研究センター 自己免疫疾患の予防及び／又は治療のための医薬組成物

Family Cites Families (36)

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US5756492A (en) 1996-09-09 1998-05-26 Sangstat Medical Corporation Graft survival prolongation with porphyrins
JP4590041B2 (ja) 1998-12-24 2010-12-01 株式会社林原生物化学研究所 臓器保存剤
US20030032634A1 (en) 2001-06-01 2003-02-13 Piganelli Jon D. Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
JP5230042B2 (ja) 1999-06-02 2013-07-10 株式会社ビーエムジー 動物の細胞または臓器の保存剤およびその保存方法。
AU5340001A (en) 2000-04-11 2001-10-23 Univ Southern California A method to prevent graft rejection using tgf-beta to induce t suppressor cells
JP2002060301A (ja) 2000-08-17 2002-02-26 Seikagaku Kogyo Co Ltd 臓器保存液
US20040171601A1 (en) 2002-07-31 2004-09-02 Dai Fukumura Photodynamic and sonodynamic therapy
US20040235162A1 (en) 2003-03-18 2004-11-25 Kirin Beer Kabushiki Kaisha Method of preparing immunoregulatory dendritic cells and the use thereof
JP4547174B2 (ja) 2003-03-18 2010-09-22 協和発酵キリン株式会社 免疫制御性樹状細胞の調製法およびその用途
US20050032210A1 (en) 2003-03-18 2005-02-10 Kirin Beer Kabushiki Kaisha Method of preparing immuno-regulatory dendritic cells and the use thereof
JP2004300098A (ja) 2003-03-31 2004-10-28 Oxygenix:Kk 移植用臓器の処理方法
JP2005306749A (ja) 2004-04-19 2005-11-04 Kringle Pharma Inc Ｈｇｆ含有臓器保存液
JP4814501B2 (ja) 2004-09-02 2011-11-16 コスモ石油株式会社 抗酸化機能向上剤
CN101010076B (zh) 2004-09-02 2010-06-09 克斯莫石油株式会社 健康功能改善剂
JP4814567B2 (ja) 2004-09-02 2011-11-16 コスモ石油株式会社 健康機能向上剤
JP4919453B2 (ja) 2005-04-07 2012-04-18 独立行政法人理化学研究所 炎症性疾患の予防又は治療剤
PL1878421T3 (pl) * 2005-04-28 2019-09-30 Sbi Pharmaceuticals Co., Ltd. Preparat do stosowania zewnętrznego na skórę
JP2006316000A (ja) 2005-05-12 2006-11-24 Vitamin C60 Bioresearch Kk 血液または臓器の保存剤と保存方法
JP2007131598A (ja) 2005-11-14 2007-05-31 Kurosu Biotech:Kk 腎移植拒絶反応抑制剤
WO2007100154A1 (ja) * 2006-03-03 2007-09-07 Riken アレルギー疾患に対する制御性樹状細胞を用いた免疫細胞療法
JP5150091B2 (ja) 2006-11-01 2013-02-20 日本澱粉工業株式会社 低酸素状態下での細胞及び心臓保存剤
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EP3192506A3 (en) * 2008-10-27 2017-10-25 SBI Pharmaceuticals Co., Ltd. Prophylactic/ameliorating agent for adult diseases comprising 5-aminolevulinic acid, derivative of 5-aminolevulinic acid, or salt of 5-aminolevulinic acid or the derivative or 5-aminolevulinic acid as active ingredient
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JP5611548B2 (ja) 2009-07-08 2014-10-22 Ｓｂｉファーマ株式会社 ５−アミノレブリン酸若しくはその誘導体、又はそれらの塩を有効成分とするがんの予防・改善剤
EP2508200B8 (en) 2009-10-21 2018-05-02 Hiasa, Yoichi Carbonic anhydrase i serving as novel antigen to be used for treatment of autoimmune diseases
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AU2011256661B2 (en) * 2010-05-19 2013-07-11 Sbi Pharmaceuticals Co., Ltd. Antimalarial drug which contains 5-aminolevulinic acid or derivative thereof as active ingredient
WO2012172821A1 (ja) * 2011-06-16 2012-12-20 Ｓｂｉファーマ株式会社 アレルギー性鼻炎の治療剤
EP2767278B1 (en) * 2011-10-12 2019-11-06 SBI Pharmaceuticals Co., Ltd. Enhancer of survival of transplanted organ
JP5369206B2 (ja) 2012-03-08 2013-12-18 コスモ石油株式会社 ５−アミノレブリン酸塩酸塩の製造方法

Also Published As

Publication number Publication date
WO2014010206A1 (ja) 2014-01-16
HK1204285A1 (en) 2015-11-13
EP2873417A4 (en) 2016-03-09
HK1205950A1 (en) 2015-12-31
JPWO2014010206A1 (ja) 2016-06-20
US9399029B2 (en) 2016-07-26
CN104411306B (zh) 2017-05-24
JP5904518B2 (ja) 2016-04-13
HUE043511T2 (hu) 2019-08-28
EP2873417A1 (en) 2015-05-20
US20150174090A1 (en) 2015-06-25
TWI619493B (zh) 2018-04-01
CN106474098B (zh) 2020-06-05
CN104411306A (zh) 2015-03-11
EP2873417B1 (en) 2019-03-06
CN106474098A (zh) 2017-03-08
TW201408285A (zh) 2014-03-01

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