PL2873417T3 - Induktor tolerancji immunologicznej - Google Patents

Induktor tolerancji immunologicznej

Info

Publication number
PL2873417T3
PL2873417T3 PL13816500T PL13816500T PL2873417T3 PL 2873417 T3 PL2873417 T3 PL 2873417T3 PL 13816500 T PL13816500 T PL 13816500T PL 13816500 T PL13816500 T PL 13816500T PL 2873417 T3 PL2873417 T3 PL 2873417T3
Authority
PL
Poland
Prior art keywords
immune tolerance
tolerance inducer
inducer
immune
tolerance
Prior art date
Application number
PL13816500T
Other languages
English (en)
Inventor
Tohru Tanaka
Motowo Nakajima
Fuminori Abe
Naomi HAGA
Kiwamu Takahashi
Hidenori Ito
Ko Rii
Original Assignee
Sbi Pharmaceuticals Co., Ltd.
National Center For Child Health And Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sbi Pharmaceuticals Co., Ltd., National Center For Child Health And Development filed Critical Sbi Pharmaceuticals Co., Ltd.
Publication of PL2873417T3 publication Critical patent/PL2873417T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • C12N5/064—Immunosuppressive dendritic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/05—Adjuvants
    • C12N2501/052—Lipopolysaccharides [LPS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2304—Interleukin-4 (IL-4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL13816500T 2012-07-13 2013-07-03 Induktor tolerancji immunologicznej PL2873417T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012157374 2012-07-13
EP13816500.6A EP2873417B1 (en) 2012-07-13 2013-07-03 Immune tolerance inducer
PCT/JP2013/004130 WO2014010206A1 (ja) 2012-07-13 2013-07-03 免疫寛容誘導剤

Publications (1)

Publication Number Publication Date
PL2873417T3 true PL2873417T3 (pl) 2019-09-30

Family

ID=49915689

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13816500T PL2873417T3 (pl) 2012-07-13 2013-07-03 Induktor tolerancji immunologicznej

Country Status (8)

Country Link
US (1) US9399029B2 (pl)
EP (1) EP2873417B1 (pl)
JP (1) JP5904518B2 (pl)
CN (2) CN106474098B (pl)
HU (1) HUE043511T2 (pl)
PL (1) PL2873417T3 (pl)
TW (1) TWI619493B (pl)
WO (1) WO2014010206A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5907357B2 (ja) 2011-10-12 2016-04-26 Ｓｂｉファーマ株式会社 移植臓器生着促進剤
CN104487067B (zh) 2012-07-19 2017-09-01 思佰益药业股份有限公司 流行性感冒病毒感染症的预防·治疗剂
WO2019141731A1 (en) 2018-01-18 2019-07-25 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Langerin+ cell targeting
GB201905940D0 (en) * 2019-04-29 2019-06-12 Intract Pharma Ltd 5-aminolevulinic acid for the local treatment of inflammatory bowel disease
EP4316479A4 (en) * 2021-03-26 2025-03-05 Tokyo Institute of Technology Pharmaceutical composition for suppressing tmprss2 expression
CN113181153B (zh) * 2021-05-31 2023-03-31 北京大学人民医院 柠檬酸在制备预防和/或治疗自身免疫病的药物中的应用
CA3253222A1 (en) * 2022-03-01 2025-07-04 Sbi Pharmaceuticals Co., Ltd. PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND/OR TREATMENT OF AUTOIMMUNE DISEASES

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SE9302431D0 (sv) 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
US5756492A (en) 1996-09-09 1998-05-26 Sangstat Medical Corporation Graft survival prolongation with porphyrins
JP4590041B2 (ja) 1998-12-24 2010-12-01 株式会社林原生物化学研究所 臓器保存剤
JP5230042B2 (ja) 1999-06-02 2013-07-10 株式会社ビーエムジー 動物の細胞または臓器の保存剤およびその保存方法。
JP5008810B2 (ja) 2000-04-11 2012-08-22 ユニバーシティ オブ サザン カリフォルニア 抑制性Ｔ細胞を誘導するためにＴＧＦ−βを用いる移植拒絶反応を防止する方法
JP2002060301A (ja) 2000-08-17 2002-02-26 Seikagaku Kogyo Co Ltd 臓器保存液
EP1439842A4 (en) 2001-06-01 2009-09-02 Nat Jewish Med & Res Center OXIDANT CAPTAIN FOR THE TREATMENT OF DIABETES OR FOR THE USE IN THE TRANSPLANTATION OR INDUCTION OF IMMUNOTOLERANE
US20040171601A1 (en) * 2002-07-31 2004-09-02 Dai Fukumura Photodynamic and sonodynamic therapy
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US20050032210A1 (en) * 2003-03-18 2005-02-10 Kirin Beer Kabushiki Kaisha Method of preparing immuno-regulatory dendritic cells and the use thereof
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JP2009143939A (ja) * 2009-01-27 2009-07-02 Tsujido Chemical Corp 治療剤
JP5611548B2 (ja) * 2009-07-08 2014-10-22 Ｓｂｉファーマ株式会社 ５−アミノレブリン酸若しくはその誘導体、又はそれらの塩を有効成分とするがんの予防・改善剤
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WO2011105394A1 (ja) 2010-02-23 2011-09-01 日本化薬株式会社 制御性樹状細胞の作製方法
CN102905702A (zh) 2010-05-19 2013-01-30 思佰益药业股份有限公司 以5-氨基乙酰丙酸或其衍生物作为有效成分的抗疟药
CN103717215B (zh) 2011-06-16 2016-08-17 思佰益药业股份有限公司 过敏性鼻炎的治疗剂
JP5907357B2 (ja) 2011-10-12 2016-04-26 Ｓｂｉファーマ株式会社 移植臓器生着促進剤
JP5369206B2 (ja) 2012-03-08 2013-12-18 コスモ石油株式会社 ５−アミノレブリン酸塩酸塩の製造方法

Also Published As

Publication number Publication date
TW201408285A (zh) 2014-03-01
EP2873417A1 (en) 2015-05-20
CN106474098B (zh) 2020-06-05
US9399029B2 (en) 2016-07-26
HK1205950A1 (en) 2015-12-31
TWI619493B (zh) 2018-04-01
CN106474098A (zh) 2017-03-08
EP2873417A4 (en) 2016-03-09
CN104411306A (zh) 2015-03-11
JPWO2014010206A1 (ja) 2016-06-20
HUE043511T2 (hu) 2019-08-28
CN104411306B (zh) 2017-05-24
EP2873417B1 (en) 2019-03-06
HK1204285A1 (en) 2015-11-13
WO2014010206A1 (ja) 2014-01-16
US20150174090A1 (en) 2015-06-25
JP5904518B2 (ja) 2016-04-13

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