PL2649068T3 - Pochodne eteru oksazolilowo-metylowego jako agoniści receptora ALX - Google Patents
Pochodne eteru oksazolilowo-metylowego jako agoniści receptora ALXInfo
- Publication number
- PL2649068T3 PL2649068T3 PL11804810T PL11804810T PL2649068T3 PL 2649068 T3 PL2649068 T3 PL 2649068T3 PL 11804810 T PL11804810 T PL 11804810T PL 11804810 T PL11804810 T PL 11804810T PL 2649068 T3 PL2649068 T3 PL 2649068T3
- Authority
- PL
- Poland
- Prior art keywords
- oxazolyl
- receptor agonists
- alx receptor
- methylether derivatives
- methylether
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2010055616 | 2010-12-07 | ||
| PCT/IB2011/055487 WO2012077049A1 (en) | 2010-12-07 | 2011-12-06 | Oxazolyl-methylether derivatives as alx receptor agonists |
| EP11804810.7A EP2649068B1 (en) | 2010-12-07 | 2011-12-06 | Oxazolyl-methylether derivatives as alx receptor agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2649068T3 true PL2649068T3 (pl) | 2015-03-31 |
Family
ID=45444667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11804810T PL2649068T3 (pl) | 2010-12-07 | 2011-12-06 | Pochodne eteru oksazolilowo-metylowego jako agoniści receptora ALX |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8846733B2 (pl) |
| EP (1) | EP2649068B1 (pl) |
| JP (1) | JP5923107B2 (pl) |
| KR (1) | KR101864463B1 (pl) |
| CN (1) | CN103261194B (pl) |
| AR (1) | AR084173A1 (pl) |
| AU (1) | AU2011340146B2 (pl) |
| CA (1) | CA2816376C (pl) |
| CY (1) | CY1116004T1 (pl) |
| DK (1) | DK2649068T3 (pl) |
| ES (1) | ES2526132T3 (pl) |
| HR (1) | HRP20150049T1 (pl) |
| MX (1) | MX2013006418A (pl) |
| PL (1) | PL2649068T3 (pl) |
| PT (1) | PT2649068E (pl) |
| RU (1) | RU2588567C2 (pl) |
| SI (1) | SI2649068T1 (pl) |
| TW (1) | TWI523853B (pl) |
| WO (1) | WO2012077049A1 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2814826C (en) | 2010-11-17 | 2019-02-12 | Actelion Pharmaceuticals Ltd | Bridged spiro[2.4]heptane ester derivatives |
| US9284288B2 (en) | 2012-05-16 | 2016-03-15 | Actelion Pharmaceuticals Ltd. | 1-(p-tolyl) cyclopropyl substituted bridged spiro[2.4]heptane derivatives as ALX receptor agonists |
| MA37618B1 (fr) | 2012-05-16 | 2017-08-31 | Actelion Pharmaceuticals Ltd | Dérivés pontés fluorés de spiro[2.4]heptane en tant qu'agonistes de récepteur alx |
| AR096686A1 (es) | 2013-06-25 | 2016-01-27 | Actelion Pharmaceuticals Ltd | Derivados de espiro[2.4]heptano puenteados sustituidos con difluoroetil-oxazol como agonistas del receptor de alx |
| WO2015007830A1 (en) | 2013-07-18 | 2015-01-22 | Actelion Pharmaceuticals Ltd | Piperazine substituted bridged spiro[2.4]heptane derivatives as alx receptor agonists |
| AR097279A1 (es) | 2013-08-09 | 2016-03-02 | Actelion Pharmaceuticals Ltd | Derivados de benzimidazolil-metil urea como agonistas del receptor de alx |
| BR112016011755B1 (pt) | 2013-11-28 | 2023-05-02 | Kyorin Pharmaceutical Co., Ltd | Derivado de ureia ou sal farmacologicamente aceitável do mesmo, seu uso e composição farmacêutica que os compreende |
| WO2016189877A1 (en) | 2015-05-27 | 2016-12-01 | Kyorin Pharmaceutical Co., Ltd. | Urea derivative or pharmacologically acceptable salt thereof |
| BR112017024966A2 (pt) | 2015-05-27 | 2018-08-07 | Kyorin Seiyaku Kk | derivado de ureia ou sal farmacologicamente aceitável do mesmo |
| CA3055093A1 (en) * | 2017-03-09 | 2018-09-13 | University Health Network | Lipoxin and lipoxin analogue mediated neuroprotection and treatments |
| KR102803660B1 (ko) | 2018-03-05 | 2025-05-02 | 브리스톨-마이어스 스큅 컴퍼니 | 페닐피롤리디논 포르밀 펩티드 2 수용체 효능제 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62234018A (ja) | 1986-04-02 | 1987-10-14 | Rooto Seiyaku Kk | 糖尿病併発症治療剤 |
| EP1319657A4 (en) | 2000-09-22 | 2005-03-02 | Nihon Nohyaku Co Ltd | N- (4-PYRAZOLYL AMIDE) DERIVATIVES, CHEMICALS FOR AGRICULTURAL AND HORTICULTURAL USE AND APPLICATIONS THEREOF |
| WO2003082314A2 (en) | 2002-04-03 | 2003-10-09 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with n-formyl peptide receptor like 1 (fprl1) |
| EP1692502A2 (en) | 2003-11-07 | 2006-08-23 | Acadia Pharmaceuticals Inc. | Use of the lipoxin receptor, fprl1, as a tool for identifying compounds effective in the treatment of pain and inflammation |
| RU2006145872A (ru) * | 2004-05-25 | 2008-06-27 | Метаболекс, Инк. (Us) | Замещенные триазолы в качестве модуляторов ppar и способы их получения |
| JP2009514858A (ja) | 2005-11-03 | 2009-04-09 | メルク エンド カムパニー インコーポレーテッド | アリール−ピラゾリルモチーフを有するヒストンデアセチラーゼ阻害剤 |
| HUE025137T2 (en) | 2007-08-21 | 2016-01-28 | Senomyx Inc | Compositions are bitter taste blocking (blocking) compounds |
| AR069650A1 (es) | 2007-12-14 | 2010-02-10 | Actelion Pharmaceuticals Ltd | Derivados de aminopirazol como agonistas no peptidicos del receptor alx humano |
| BRPI0821115A8 (pt) | 2007-12-18 | 2017-12-26 | Actelion Pharmaceuticals Ltd | Composto derivado de aminotriazol, medicamento, composição farmacêutica e uso do composto |
| HRP20130972T1 (hr) | 2009-05-18 | 2013-11-22 | Actelion Pharmaceuticals Ltd. | Premošteni derivati spiro [2,4] heptana kao alx-receptori i/ili fprl2-agonisti |
| CN101909306A (zh) * | 2009-06-08 | 2010-12-08 | 中兴通讯股份有限公司 | 中继站管理方法及基站 |
| RU2544862C2 (ru) | 2009-06-09 | 2015-03-20 | Актелион Фармасьютиклз Лтд | Фторированные аминотриазольные производные |
| CA2760887A1 (en) | 2009-06-12 | 2010-12-16 | Actelion Pharmaceuticals Ltd | Oxazole and thiazole derivatives as alx receptor agonists |
| JP2012254939A (ja) * | 2009-10-07 | 2012-12-27 | Astellas Pharma Inc | オキサゾール化合物 |
-
2011
- 2011-12-06 TW TW100144916A patent/TWI523853B/zh not_active IP Right Cessation
- 2011-12-06 CA CA2816376A patent/CA2816376C/en not_active Expired - Fee Related
- 2011-12-06 CN CN201180058458.7A patent/CN103261194B/zh not_active Expired - Fee Related
- 2011-12-06 EP EP11804810.7A patent/EP2649068B1/en not_active Not-in-force
- 2011-12-06 MX MX2013006418A patent/MX2013006418A/es active IP Right Grant
- 2011-12-06 HR HRP20150049AT patent/HRP20150049T1/hr unknown
- 2011-12-06 DK DK11804810.7T patent/DK2649068T3/en active
- 2011-12-06 ES ES11804810.7T patent/ES2526132T3/es active Active
- 2011-12-06 JP JP2013542652A patent/JP5923107B2/ja not_active Expired - Fee Related
- 2011-12-06 RU RU2013130879/04A patent/RU2588567C2/ru not_active IP Right Cessation
- 2011-12-06 US US13/992,143 patent/US8846733B2/en not_active Expired - Fee Related
- 2011-12-06 PL PL11804810T patent/PL2649068T3/pl unknown
- 2011-12-06 KR KR1020137017686A patent/KR101864463B1/ko not_active Expired - Fee Related
- 2011-12-06 SI SI201130348T patent/SI2649068T1/sl unknown
- 2011-12-06 WO PCT/IB2011/055487 patent/WO2012077049A1/en not_active Ceased
- 2011-12-06 PT PT118048107T patent/PT2649068E/pt unknown
- 2011-12-06 AU AU2011340146A patent/AU2011340146B2/en not_active Ceased
- 2011-12-06 AR ARP110104559A patent/AR084173A1/es unknown
-
2015
- 2015-01-23 CY CY20151100075T patent/CY1116004T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012077049A1 (en) | 2012-06-14 |
| KR101864463B1 (ko) | 2018-06-04 |
| JP5923107B2 (ja) | 2016-05-24 |
| CA2816376C (en) | 2018-11-20 |
| CN103261194A (zh) | 2013-08-21 |
| HRP20150049T1 (hr) | 2015-02-27 |
| EP2649068B1 (en) | 2014-10-29 |
| CA2816376A1 (en) | 2012-06-14 |
| SI2649068T1 (sl) | 2015-01-30 |
| KR20130133240A (ko) | 2013-12-06 |
| TW201305151A (zh) | 2013-02-01 |
| PT2649068E (pt) | 2014-12-23 |
| RU2588567C2 (ru) | 2016-07-10 |
| MX2013006418A (es) | 2013-07-15 |
| AR084173A1 (es) | 2013-04-24 |
| JP2013544878A (ja) | 2013-12-19 |
| CN103261194B (zh) | 2016-02-24 |
| DK2649068T3 (en) | 2014-12-08 |
| US20130261159A1 (en) | 2013-10-03 |
| AU2011340146B2 (en) | 2016-05-19 |
| EP2649068A1 (en) | 2013-10-16 |
| CY1116004T1 (el) | 2017-01-25 |
| RU2013130879A (ru) | 2015-01-20 |
| US8846733B2 (en) | 2014-09-30 |
| AU2011340146A1 (en) | 2013-07-25 |
| TWI523853B (zh) | 2016-03-01 |
| ES2526132T3 (es) | 2015-01-07 |
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