PL2470545T3 - Bezwodne postaci pochodnej pirydyny - Google Patents
Bezwodne postaci pochodnej pirydynyInfo
- Publication number
- PL2470545T3 PL2470545T3 PL10747619T PL10747619T PL2470545T3 PL 2470545 T3 PL2470545 T3 PL 2470545T3 PL 10747619 T PL10747619 T PL 10747619T PL 10747619 T PL10747619 T PL 10747619T PL 2470545 T3 PL2470545 T3 PL 2470545T3
- Authority
- PL
- Poland
- Prior art keywords
- pyridine derivative
- anhydrate forms
- anhydrate
- forms
- pyridine
- Prior art date
Links
- 150000003222 pyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23743509P | 2009-08-27 | 2009-08-27 | |
| EP10747619.4A EP2470545B1 (en) | 2009-08-27 | 2010-08-25 | Anhydrate forms of a pyridine derivative |
| PCT/EP2010/062420 WO2011023733A1 (en) | 2009-08-27 | 2010-08-25 | Anhydrate forms of a pyridine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2470545T3 true PL2470545T3 (pl) | 2014-03-31 |
Family
ID=42790943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10747619T PL2470545T3 (pl) | 2009-08-27 | 2010-08-25 | Bezwodne postaci pochodnej pirydyny |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8796269B2 (h) |
| EP (1) | EP2470545B1 (h) |
| JP (3) | JP2013503134A (h) |
| KR (1) | KR20120056258A (h) |
| CN (1) | CN102639536B (h) |
| AU (1) | AU2010288502B2 (h) |
| BR (1) | BR112012003435A2 (h) |
| CA (1) | CA2772168C (h) |
| DK (1) | DK2470545T3 (h) |
| EA (1) | EA021411B1 (h) |
| ES (1) | ES2440938T3 (h) |
| IL (1) | IL217922A (h) |
| IN (1) | IN2012DN01292A (h) |
| MX (1) | MX2012002369A (h) |
| PL (1) | PL2470545T3 (h) |
| SG (1) | SG178231A1 (h) |
| WO (1) | WO2011023733A1 (h) |
| ZA (1) | ZA201200812B (h) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011023733A1 (en) * | 2009-08-27 | 2011-03-03 | Glaxosmithkline Llc | Anhydrate forms of a pyridine derivative |
| EP3915560A1 (en) * | 2014-06-25 | 2021-12-01 | Emory University | Methods of managing conditioned fear with neurokinin receptor antagonists |
| SI3297631T1 (sl) * | 2015-05-18 | 2019-12-31 | Nerre Therapeutics Limited | Antagonist NK-1/NK-3 receptorja za zdravljenje oblivov vročine |
| ES2901616T3 (es) * | 2016-12-15 | 2022-03-23 | Glaxosmithkline Ip Dev Ltd | Compuestos NRF2 |
| PT3765024T (pt) | 2018-03-14 | 2024-02-19 | Kandy Therapeutics Ltd | Formulação farmacêutica inovadora que compreende antagonistas duplos dos recetores nk-1/nk-3 |
| WO2021030335A1 (en) * | 2019-08-12 | 2021-02-18 | Millendo Therapeutics, Inc. | A stereoisomerically pure nk-3 receptor antagonist and crystalline forms thereof |
| CN118496152A (zh) | 2019-11-15 | 2024-08-16 | 康堤医疗有限公司 | 制备nt-814的关键中间体6-氯-4-(4-氟-2-甲基苯基)吡啶-3-胺的新化学方法 |
| EP4431512A1 (en) | 2023-03-16 | 2024-09-18 | Bayer Consumer Care AG | Novel dual nk-1/nk-3 receptor antagonists |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1035115B1 (en) * | 1999-02-24 | 2004-09-29 | F. Hoffmann-La Roche Ag | 4-Phenylpyridine derivatives and their use as NK-1 receptor antagonists |
| GB0203022D0 (en) * | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
| ES2290666T3 (es) * | 2003-01-31 | 2008-02-16 | F. Hoffmann-La Roche Ag | Nueva modificacion cristalina de la 2-(3,5-bis-trifluormetil-fenil)-n-(6-(1,1-dioxo-1landa6-tiomorfolin-4-il)-4-(4-fluor-2-metil-fenil)-piridin-3-il)-n-metil-isobutiramida. |
| ATE371451T1 (de) * | 2003-07-03 | 2007-09-15 | Hoffmann La Roche | Duale nk1/nk3 antagonisten zur behandlung von schizophrenie |
| EP2336136A1 (en) * | 2005-09-09 | 2011-06-22 | GlaxoSmithKline LLC | Pyridine derivatives and their use in the treatment of psychotic disorders |
| KR20100101051A (ko) * | 2007-12-11 | 2010-09-16 | 씨아이피엘에이 엘티디. | 조피클론 결정성 다형체, 이들의 제조 공정 및 이들의 약제 조성물 |
| GB0814340D0 (en) * | 2008-08-05 | 2008-09-10 | Smithkline Beecham Corp | Anhydrous crystol form fo a pyridine derivative |
| WO2011023733A1 (en) * | 2009-08-27 | 2011-03-03 | Glaxosmithkline Llc | Anhydrate forms of a pyridine derivative |
| JP6342662B2 (ja) * | 2014-01-29 | 2018-06-13 | 京セラ株式会社 | ドリルおよびそれを用いた切削加工物の製造方法 |
-
2010
- 2010-08-25 WO PCT/EP2010/062420 patent/WO2011023733A1/en active Application Filing
- 2010-08-25 JP JP2012526048A patent/JP2013503134A/ja active Pending
- 2010-08-25 EP EP10747619.4A patent/EP2470545B1/en active Active
- 2010-08-25 AU AU2010288502A patent/AU2010288502B2/en active Active
- 2010-08-25 EA EA201270302A patent/EA021411B1/ru not_active IP Right Cessation
- 2010-08-25 ES ES10747619.4T patent/ES2440938T3/es active Active
- 2010-08-25 KR KR1020127004865A patent/KR20120056258A/ko not_active Ceased
- 2010-08-25 BR BR112012003435A patent/BR112012003435A2/pt not_active Application Discontinuation
- 2010-08-25 PL PL10747619T patent/PL2470545T3/pl unknown
- 2010-08-25 SG SG2012007464A patent/SG178231A1/en unknown
- 2010-08-25 IN IN1292DEN2012 patent/IN2012DN01292A/en unknown
- 2010-08-25 US US13/389,525 patent/US8796269B2/en active Active
- 2010-08-25 CN CN201080037918.3A patent/CN102639536B/zh active Active
- 2010-08-25 DK DK10747619.4T patent/DK2470545T3/da active
- 2010-08-25 CA CA2772168A patent/CA2772168C/en active Active
- 2010-08-25 MX MX2012002369A patent/MX2012002369A/es active IP Right Grant
-
2012
- 2012-02-02 ZA ZA2012/00812A patent/ZA201200812B/en unknown
- 2012-02-02 IL IL217922A patent/IL217922A/en active IP Right Grant
-
2015
- 2015-07-13 JP JP2015139845A patent/JP6404186B2/ja active Active
-
2017
- 2017-06-09 JP JP2017114602A patent/JP2017193564A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010288502B2 (en) | 2013-12-12 |
| CA2772168A1 (en) | 2011-03-03 |
| JP2016000739A (ja) | 2016-01-07 |
| EA201270302A1 (ru) | 2012-07-30 |
| DK2470545T3 (da) | 2014-01-13 |
| JP2017193564A (ja) | 2017-10-26 |
| EP2470545A1 (en) | 2012-07-04 |
| EA021411B1 (ru) | 2015-06-30 |
| EP2470545B1 (en) | 2013-10-09 |
| WO2011023733A1 (en) | 2011-03-03 |
| JP2013503134A (ja) | 2013-01-31 |
| BR112012003435A2 (pt) | 2016-02-23 |
| CN102639536B (zh) | 2015-03-18 |
| JP6404186B2 (ja) | 2018-10-10 |
| AU2010288502A1 (en) | 2012-02-23 |
| KR20120056258A (ko) | 2012-06-01 |
| US20120157450A1 (en) | 2012-06-21 |
| SG178231A1 (en) | 2012-03-29 |
| MX2012002369A (es) | 2012-03-29 |
| ZA201200812B (en) | 2013-03-27 |
| ES2440938T3 (es) | 2014-01-31 |
| CA2772168C (en) | 2019-01-08 |
| CN102639536A (zh) | 2012-08-15 |
| IL217922A (en) | 2016-06-30 |
| IN2012DN01292A (h) | 2015-06-05 |
| IL217922A0 (en) | 2012-03-29 |
| US8796269B2 (en) | 2014-08-05 |
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