PL2268644T3 - Tricykliczne pochodne piperydyny, leki zawierające te związki, ich zastosowanie i sposoby ich wytwarzania - Google Patents

Tricykliczne pochodne piperydyny, leki zawierające te związki, ich zastosowanie i sposoby ich wytwarzania

Info

Publication number
PL2268644T3
PL2268644T3 PL09716535T PL09716535T PL2268644T3 PL 2268644 T3 PL2268644 T3 PL 2268644T3 PL 09716535 T PL09716535 T PL 09716535T PL 09716535 T PL09716535 T PL 09716535T PL 2268644 T3 PL2268644 T3 PL 2268644T3
Authority
PL
Poland
Prior art keywords
compounds
preparation
pyridine derivatives
medicaments containing
tricyclic pyridine
Prior art date
Application number
PL09716535T
Other languages
English (en)
Inventor
Holger Wagner
Daniela Berta
Riccardo Giovannini
Alessandro Mazzacani
Ruediger Streicher
Klaus Fuchs
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of PL2268644T3 publication Critical patent/PL2268644T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL09716535T 2008-03-05 2009-03-02 Tricykliczne pochodne piperydyny, leki zawierające te związki, ich zastosowanie i sposoby ich wytwarzania PL2268644T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP08152288 2008-03-05
EP08161366 2008-07-29
PCT/EP2009/052459 WO2009109549A1 (en) 2008-03-05 2009-03-02 Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
EP09716535A EP2268644B1 (en) 2008-03-05 2009-03-02 Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation

Publications (1)

Publication Number Publication Date
PL2268644T3 true PL2268644T3 (pl) 2012-01-31

Family

ID=40548681

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09716535T PL2268644T3 (pl) 2008-03-05 2009-03-02 Tricykliczne pochodne piperydyny, leki zawierające te związki, ich zastosowanie i sposoby ich wytwarzania

Country Status (21)

Country Link
US (1) US8703793B2 (pl)
EP (1) EP2268644B1 (pl)
JP (1) JP5291126B2 (pl)
KR (1) KR20100122089A (pl)
CN (1) CN102015722A (pl)
AR (1) AR070788A1 (pl)
AT (1) ATE520696T1 (pl)
AU (1) AU2009221179A1 (pl)
BR (1) BRPI0909105A2 (pl)
CA (1) CA2717013A1 (pl)
CL (1) CL2009000510A1 (pl)
DK (1) DK2268644T3 (pl)
ES (1) ES2372012T3 (pl)
IL (1) IL207263A0 (pl)
MX (1) MX2010009607A (pl)
NZ (1) NZ587748A (pl)
PL (1) PL2268644T3 (pl)
RU (1) RU2010140442A (pl)
TW (1) TW200942547A (pl)
WO (1) WO2009109549A1 (pl)
ZA (1) ZA201005315B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009109549A1 (en) 2008-03-05 2009-09-11 Boehringer Ingelheim International Gmbh Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
CA2790643A1 (en) * 2010-02-19 2011-08-25 Boehringer Ingelheim International Gmbh Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
EP2592076B1 (en) 2010-07-09 2015-05-13 Daiichi Sankyo Company, Limited Substituted pyridine compound
US20130053404A1 (en) * 2011-02-17 2013-02-28 Boehringer Ingelheim International Gmbh Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
JP5947382B2 (ja) 2011-08-17 2016-07-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング フロ［３，４−ｃ］キノリン誘導体、このような化合物を含む薬物、それらの使用及びそれらの調製方法
WO2013024149A1 (en) * 2011-08-18 2013-02-21 Boehringer Ingelheim International Gmbh Crystalline forms of octahydro-3h-spiro [furo [3, 4-c] quinoline -1, 4 '-pyran] -9-ol
TWI570118B (zh) 2012-01-06 2017-02-11 第一三共股份有限公司 經取代之吡啶化合物的酸加成鹽
CN110950881A (zh) * 2018-09-27 2020-04-03 中国科学院上海药物研究所 一类三环类似物、其制备方法和用途

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4798619A (en) * 1980-06-02 1989-01-17 American Cyanamid Co. 2-(2-imidazolin-2-yl)-pyridines and quinolines and use of said compounds as herbicidal agents
KR900701792A (ko) * 1988-08-16 1990-12-04 로버어트 에이 아미테이지 Acat 효소를 차단하는데 효과적인 이가 리간드
JP4108123B2 (ja) * 1995-09-29 2008-06-25 グラクソスミスクライン・ソシエタ・ペル・アチオニ Ｎｍｄａアンタゴニストとしてのテトラヒドロキノリン
DE19627431A1 (de) * 1996-07-08 1998-01-15 Bayer Ag Heterocyclisch kondensierte Pyridine
HRP970330B1 (en) * 1996-07-08 2004-06-30 Bayer Ag Cycloalkano pyridines
CA2302350A1 (en) 1997-09-04 1999-03-11 Basf Aktiengesellschaft Novel carboxylic acid derivatives, their production and their use as mixed eta/etb endothelin-receptor antagonists
DE19741051A1 (de) 1997-09-18 1999-03-25 Bayer Ag Hetero-Tetrahydrochinoline
MA24643A1 (fr) * 1997-09-18 1999-04-01 Bayer Ag Tetrahydro-naphtalenes substitues et composes analogues
US20010018446A1 (en) * 1999-09-23 2001-08-30 G.D. Searle & Co. Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
DE10148436A1 (de) 2001-10-01 2003-04-17 Bayer Ag Tetrahydrochinoline
PE20060653A1 (es) 2004-08-31 2006-09-27 Glaxo Group Ltd Derivados triciclicos condensados como moduladores del receptor 5-ht1
DE102004060997A1 (de) * 2004-12-18 2006-06-22 Bayer Healthcare Ag Chemische Verbindung und ihre Verwendung
BRPI0519566A2 (pt) * 2004-12-18 2009-01-27 Bayer Healthcare Ag derivados de (5s)-3-[(s)-fléor(4-trifluormetilfenil)metil]-5,6,7,8-tet raidroquinolin-5-ol e seu uso como inibidores de cetp
KR20070090248A (ko) * 2004-12-18 2007-09-05 바이엘 헬스케어 아게 4-시클로알킬-치환된 테트라히드로퀴놀린 유도체 및 그의약제로서의 용도
WO2009109549A1 (en) 2008-03-05 2009-09-11 Boehringer Ingelheim International Gmbh Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
CA2790643A1 (en) * 2010-02-19 2011-08-25 Boehringer Ingelheim International Gmbh Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
US20130053404A1 (en) * 2011-02-17 2013-02-28 Boehringer Ingelheim International Gmbh Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
JP5947382B2 (ja) * 2011-08-17 2016-07-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング フロ［３，４−ｃ］キノリン誘導体、このような化合物を含む薬物、それらの使用及びそれらの調製方法
WO2013024149A1 (en) * 2011-08-18 2013-02-21 Boehringer Ingelheim International Gmbh Crystalline forms of octahydro-3h-spiro [furo [3, 4-c] quinoline -1, 4 '-pyran] -9-ol

Also Published As

Publication number Publication date
DK2268644T3 (da) 2011-10-10
CN102015722A (zh) 2011-04-13
WO2009109549A1 (en) 2009-09-11
CA2717013A1 (en) 2009-09-11
MX2010009607A (es) 2010-09-30
JP2011513361A (ja) 2011-04-28
JP5291126B2 (ja) 2013-09-18
ATE520696T1 (de) 2011-09-15
TW200942547A (en) 2009-10-16
CL2009000510A1 (es) 2010-04-09
ZA201005315B (en) 2011-03-30
BRPI0909105A2 (pt) 2015-08-25
KR20100122089A (ko) 2010-11-19
ES2372012T3 (es) 2012-01-12
EP2268644B1 (en) 2011-08-17
US20110021550A1 (en) 2011-01-27
AR070788A1 (es) 2010-05-05
US8703793B2 (en) 2014-04-22
NZ587748A (en) 2012-01-12
IL207263A0 (en) 2010-12-30
RU2010140442A (ru) 2012-04-10
AU2009221179A1 (en) 2009-09-11
EP2268644A1 (en) 2011-01-05

Similar Documents

Publication Publication Date Title
IL205759A (en) History of isoxazolo-pyridine, a process for their preparation and the drugs containing them
IL219530A0 (en) Substituted 4-aminocyclohexane derivatives and their use for preparing medicaments
IL193340A0 (en) Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
IL206394A (en) Derivatives of 2-Benzylpyridine Filtration as Met Kinase Inhibitors, Process for their Preparation, Medication and Use
IL219602A (en) Tricyclic compounds containing pyrazole, a process for their preparation and their pharmaceutical compositions
IL205742A (en) 4 - (4-Cyano-2-Theoaryl) dihydropyrimidinones, their preparation processes, medications containing them and their use
IL208336A (en) Pyridazinone derivatives, drugs containing them and their uses and process for preparation
PL2364983T3 (pl) Nowa pochodna tricykliczna lub jej farmaceutycznie dopuszczalne sole, sposób jej wytwarzania, oraz zawierająca ją kompozycja farmaceutyczna
IL205665A (en) The history of terroiril, the process of preparing them, the drugs containing them and their use in the preparation of drugs
IL196525A (en) A history of spirocyclic azindole, a process for their preparation and medications containing them
SI2107055T1 (sl) Derivati diosmetina, postopek za njihovo pripravo in njihovi farmacevtski sestavki
IL207263A0 (en) Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
IL193339A0 (en) Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
IL193341A0 (en) Novel azacyclyl-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
IL206492A0 (en) Spirocyclic heterocycles, medicaments containing said compounds, use thereof and method for their production
AP2012006390A0 (en) Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
IL210377A (en) History of Naphthyridone, their preparation and their pharmaceutical preparations
IL207183A (en) Dihydroindolone compounds, a process for their preparation and their pharmaceutical compositions
IL200128A0 (en) New tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them
IL205710A (en) History of Spiro [Pipyridine-Benzopyran] Pharmaceuticals Containing Them, Methods of Preparing and Using Their @
IL212942A (en) History of Rifamycin, Methods of Preparation, Pharmaceutical Preparations Containing Them and Their Uses
IL205082A0 (en) Process for the preparation of tetranorlabdane derivatives
ZA201104945B (en) Substituted 6-(2-aminobenzylamino)purine derivatives, their use as medicaments and preparations containing these compounds
IL213588A0 (en) Naphthyridine derivatives, their preparation and pharmaceutical compositions containing them
IL214704A0 (en) Oxazole pyridine derivatives, their preparation and pharmaceutical composition containing them