ATE520696T1 - Tricyclische pyridinderivate, solche verbindungen enthaltende medikamente, ihre verwendung und verfahren zu ihrer herstellung - Google Patents
Tricyclische pyridinderivate, solche verbindungen enthaltende medikamente, ihre verwendung und verfahren zu ihrer herstellungInfo
- Publication number
- ATE520696T1 ATE520696T1 AT09716535T AT09716535T ATE520696T1 AT E520696 T1 ATE520696 T1 AT E520696T1 AT 09716535 T AT09716535 T AT 09716535T AT 09716535 T AT09716535 T AT 09716535T AT E520696 T1 ATE520696 T1 AT E520696T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- production
- pyridine derivatives
- medications containing
- tricyclic pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08152288 | 2008-03-05 | ||
EP08161366 | 2008-07-29 | ||
PCT/EP2009/052459 WO2009109549A1 (en) | 2008-03-05 | 2009-03-02 | Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE520696T1 true ATE520696T1 (de) | 2011-09-15 |
Family
ID=40548681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT09716535T ATE520696T1 (de) | 2008-03-05 | 2009-03-02 | Tricyclische pyridinderivate, solche verbindungen enthaltende medikamente, ihre verwendung und verfahren zu ihrer herstellung |
Country Status (21)
Country | Link |
---|---|
US (1) | US8703793B2 (de) |
EP (1) | EP2268644B1 (de) |
JP (1) | JP5291126B2 (de) |
KR (1) | KR20100122089A (de) |
CN (1) | CN102015722A (de) |
AR (1) | AR070788A1 (de) |
AT (1) | ATE520696T1 (de) |
AU (1) | AU2009221179A1 (de) |
BR (1) | BRPI0909105A2 (de) |
CA (1) | CA2717013A1 (de) |
CL (1) | CL2009000510A1 (de) |
DK (1) | DK2268644T3 (de) |
ES (1) | ES2372012T3 (de) |
IL (1) | IL207263A0 (de) |
MX (1) | MX2010009607A (de) |
NZ (1) | NZ587748A (de) |
PL (1) | PL2268644T3 (de) |
RU (1) | RU2010140442A (de) |
TW (1) | TW200942547A (de) |
WO (1) | WO2009109549A1 (de) |
ZA (1) | ZA201005315B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5291126B2 (ja) | 2008-03-05 | 2013-09-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 三環式ピリジン誘導体、そのような化合物を含有する医薬、それらの使用及びそれらの調製方法 |
BR112012020591A2 (pt) * | 2010-02-19 | 2017-10-10 | Boehringer Ingelheim Int | derivados de piridina tricíclica, medicamentos contendo tais compostos, seu uso e processo para sua preparação. |
MX2013000359A (es) | 2010-07-09 | 2013-02-11 | Ube Industries | Compuesto de piridina sustituida. |
US20130053404A1 (en) * | 2011-02-17 | 2013-02-28 | Boehringer Ingelheim International Gmbh | Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation |
AR087577A1 (es) | 2011-08-17 | 2014-04-03 | Boehringer Ingelheim Int | Derivados de furo[3,4-c]quinolina, medicamentos que contienen dichos compuestos, su uso y proceso para su preparacion |
US20130210851A1 (en) * | 2011-08-18 | 2013-08-15 | Boehringer Ingelheim International Gmbh | Crystalline forms of a hexahydrofuro[3,4-c]quinoline derivative |
CA2860601C (en) | 2012-01-06 | 2016-07-05 | Daiichi Sankyo Company, Limited | Acid addition salt of substituted pyridine compound |
CN110950881A (zh) * | 2018-09-27 | 2020-04-03 | 中国科学院上海药物研究所 | 一类三环类似物、其制备方法和用途 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4798619A (en) * | 1980-06-02 | 1989-01-17 | American Cyanamid Co. | 2-(2-imidazolin-2-yl)-pyridines and quinolines and use of said compounds as herbicidal agents |
ATE114311T1 (de) * | 1988-08-16 | 1994-12-15 | Upjohn Co | Bivalente liganden, wirksam für die blockierung des enzyms acat. |
CA2232509A1 (en) * | 1995-09-29 | 1997-04-10 | Glaxo Wellcome Spa | Tetrahydroquinolines as nmda antagonists |
HRP970330B1 (en) * | 1996-07-08 | 2004-06-30 | Bayer Ag | Cycloalkano pyridines |
DE19627431A1 (de) * | 1996-07-08 | 1998-01-15 | Bayer Ag | Heterocyclisch kondensierte Pyridine |
JP2001514254A (ja) | 1997-09-04 | 2001-09-11 | ビーエーエスエフ アクチェンゲゼルシャフト | 新規カルボン酸誘導体、その製造及び混合eta/etbエンドセリン受容体拮抗薬としてのその使用 |
DE19741051A1 (de) * | 1997-09-18 | 1999-03-25 | Bayer Ag | Hetero-Tetrahydrochinoline |
MA24643A1 (fr) * | 1997-09-18 | 1999-04-01 | Bayer Ag | Tetrahydro-naphtalenes substitues et composes analogues |
US20010018446A1 (en) * | 1999-09-23 | 2001-08-30 | G.D. Searle & Co. | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity |
DE10148436A1 (de) | 2001-10-01 | 2003-04-17 | Bayer Ag | Tetrahydrochinoline |
PE20060653A1 (es) | 2004-08-31 | 2006-09-27 | Glaxo Group Ltd | Derivados triciclicos condensados como moduladores del receptor 5-ht1 |
JP2008524137A (ja) | 2004-12-18 | 2008-07-10 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | (5s)−3−[(s)−フルオロ(4−トリフルオロメチルフェニル)メチル−5,6,7,8−テトラヒドロキノリン−5−オール誘導体およびcetp阻害剤としてのそれらの使用 |
RU2393151C2 (ru) * | 2004-12-18 | 2010-06-27 | Байер Шеринг Фарма Акциенгезельшафт | 4-циклоалкилзамещенные производные тетрагидрохинолина и их применение в качестве лекарств |
DE102004060997A1 (de) * | 2004-12-18 | 2006-06-22 | Bayer Healthcare Ag | Chemische Verbindung und ihre Verwendung |
JP5291126B2 (ja) | 2008-03-05 | 2013-09-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 三環式ピリジン誘導体、そのような化合物を含有する医薬、それらの使用及びそれらの調製方法 |
BR112012020591A2 (pt) * | 2010-02-19 | 2017-10-10 | Boehringer Ingelheim Int | derivados de piridina tricíclica, medicamentos contendo tais compostos, seu uso e processo para sua preparação. |
US20130053404A1 (en) * | 2011-02-17 | 2013-02-28 | Boehringer Ingelheim International Gmbh | Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation |
AR087577A1 (es) * | 2011-08-17 | 2014-04-03 | Boehringer Ingelheim Int | Derivados de furo[3,4-c]quinolina, medicamentos que contienen dichos compuestos, su uso y proceso para su preparacion |
US20130210851A1 (en) * | 2011-08-18 | 2013-08-15 | Boehringer Ingelheim International Gmbh | Crystalline forms of a hexahydrofuro[3,4-c]quinoline derivative |
-
2009
- 2009-03-02 JP JP2010549118A patent/JP5291126B2/ja active Active
- 2009-03-02 EP EP09716535A patent/EP2268644B1/de active Active
- 2009-03-02 KR KR1020107019634A patent/KR20100122089A/ko not_active Application Discontinuation
- 2009-03-02 WO PCT/EP2009/052459 patent/WO2009109549A1/en active Application Filing
- 2009-03-02 RU RU2010140442/04A patent/RU2010140442A/ru not_active Application Discontinuation
- 2009-03-02 ES ES09716535T patent/ES2372012T3/es active Active
- 2009-03-02 NZ NZ587748A patent/NZ587748A/en not_active IP Right Cessation
- 2009-03-02 US US12/920,722 patent/US8703793B2/en active Active
- 2009-03-02 BR BRPI0909105-0A patent/BRPI0909105A2/pt not_active IP Right Cessation
- 2009-03-02 AU AU2009221179A patent/AU2009221179A1/en not_active Abandoned
- 2009-03-02 CN CN2009801139131A patent/CN102015722A/zh active Pending
- 2009-03-02 DK DK09716535.1T patent/DK2268644T3/da active
- 2009-03-02 MX MX2010009607A patent/MX2010009607A/es active IP Right Grant
- 2009-03-02 CA CA2717013A patent/CA2717013A1/en not_active Abandoned
- 2009-03-02 PL PL09716535T patent/PL2268644T3/pl unknown
- 2009-03-02 AT AT09716535T patent/ATE520696T1/de active
- 2009-03-04 AR ARP090100766A patent/AR070788A1/es unknown
- 2009-03-04 TW TW098107019A patent/TW200942547A/zh unknown
- 2009-03-04 CL CL2009000510A patent/CL2009000510A1/es unknown
-
2010
- 2010-07-26 ZA ZA2010/05315A patent/ZA201005315B/en unknown
- 2010-07-28 IL IL207263A patent/IL207263A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
TW200942547A (en) | 2009-10-16 |
JP2011513361A (ja) | 2011-04-28 |
DK2268644T3 (da) | 2011-10-10 |
WO2009109549A1 (en) | 2009-09-11 |
US20110021550A1 (en) | 2011-01-27 |
JP5291126B2 (ja) | 2013-09-18 |
AR070788A1 (es) | 2010-05-05 |
RU2010140442A (ru) | 2012-04-10 |
BRPI0909105A2 (pt) | 2015-08-25 |
CN102015722A (zh) | 2011-04-13 |
AU2009221179A1 (en) | 2009-09-11 |
EP2268644B1 (de) | 2011-08-17 |
US8703793B2 (en) | 2014-04-22 |
IL207263A0 (en) | 2010-12-30 |
CA2717013A1 (en) | 2009-09-11 |
KR20100122089A (ko) | 2010-11-19 |
ES2372012T3 (es) | 2012-01-12 |
NZ587748A (en) | 2012-01-12 |
MX2010009607A (es) | 2010-09-30 |
ZA201005315B (en) | 2011-03-30 |
PL2268644T3 (pl) | 2012-01-31 |
EP2268644A1 (de) | 2011-01-05 |
CL2009000510A1 (es) | 2010-04-09 |
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Legal Events
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UEP | Publication of translation of european patent specification |
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