PL1858861T3 - Hamujące HIV 2-(4-cyjanofenylo)-6-hydroksyloaminopirymidyny - Google Patents

Hamujące HIV 2-(4-cyjanofenylo)-6-hydroksyloaminopirymidyny

Info

Publication number
PL1858861T3
PL1858861T3 PL06708609T PL06708609T PL1858861T3 PL 1858861 T3 PL1858861 T3 PL 1858861T3 PL 06708609 T PL06708609 T PL 06708609T PL 06708609 T PL06708609 T PL 06708609T PL 1858861 T3 PL1858861 T3 PL 1858861T3
Authority
PL
Poland
Prior art keywords
hydroxylaminopyrimidines
cyanophenyl
compounds
hiv inhibiting
hiv
Prior art date
Application number
PL06708609T
Other languages
English (en)
Inventor
Kock Herman Augustinus De
Piet Tom Bert Paul Wigerinck
Original Assignee
Janssen Sciences Ireland Uc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Uc filed Critical Janssen Sciences Ireland Uc
Publication of PL1858861T3 publication Critical patent/PL1858861T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL06708609T 2005-03-04 2006-03-02 Hamujące HIV 2-(4-cyjanofenylo)-6-hydroksyloaminopirymidyny PL1858861T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05101707 2005-03-04
PCT/EP2006/060407 WO2006094930A1 (en) 2005-03-04 2006-03-02 Hiv inhibiting 2-(4-cyanophenyl)-6-hydroxylaminopyrimidines
EP06708609A EP1858861B1 (en) 2005-03-04 2006-03-02 Hiv inhibiting 2-(4-cyanophenyl)-6-hydroxylaminopyrimidines

Publications (1)

Publication Number Publication Date
PL1858861T3 true PL1858861T3 (pl) 2010-12-31

Family

ID=34938904

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06708609T PL1858861T3 (pl) 2005-03-04 2006-03-02 Hamujące HIV 2-(4-cyjanofenylo)-6-hydroksyloaminopirymidyny

Country Status (20)

Country Link
US (2) US20080214588A1 (pl)
EP (1) EP1858861B1 (pl)
JP (1) JP5118978B2 (pl)
CN (1) CN101133038B (pl)
AT (1) ATE473212T1 (pl)
AU (1) AU2006222057B2 (pl)
BR (1) BRPI0609291B1 (pl)
CY (1) CY1111102T1 (pl)
DE (1) DE602006015291D1 (pl)
DK (1) DK1858861T3 (pl)
ES (1) ES2347815T3 (pl)
HR (1) HRP20100504T1 (pl)
ME (1) ME01229B (pl)
MX (1) MX2007010744A (pl)
PL (1) PL1858861T3 (pl)
PT (1) PT1858861E (pl)
RS (1) RS51435B (pl)
RU (1) RU2401261C2 (pl)
SI (1) SI1858861T1 (pl)
WO (1) WO2006094930A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007010051A (es) * 2005-02-18 2007-09-21 Tibotec Pharm Ltd Derivados de oxido de 2-(4-cianofenilamino)pirimidina que inhiben el virus de inmunodeficiencia humana.
ES2550152T3 (es) 2006-12-13 2015-11-04 F. Hoffmann-La Roche Ag Derivados de 2-(piperidin-4-il)-4-fenoxi-o fenilamino-pirimidina como inhibidores no nucleósidos de transcriptasa inversa
WO2010150279A2 (en) * 2009-06-22 2010-12-29 Emcure Pharmaceuticals Limited Process for synthesis of diarylpyrimidine non-nucleoside reverse transcriptase inhibitor
US8153790B2 (en) 2009-07-27 2012-04-10 Krizmanic Irena Process for the preparation and purification of etravirine and intermediates thereof
CN101993419B (zh) * 2009-08-20 2013-01-16 浙江九洲药业股份有限公司 一种4-[(5-溴-4,6-二氯-2-嘧啶基)氨基]苯甲腈的制备方法
GR1007010B (el) 2009-10-08 2010-10-07 Χημικα Και Βιοφαρμακευτικα Εργαστηρια Πατρων Αε (Cbl-Patras), Ινσουλινοειδη πεπτιδια
WO2011135578A1 (en) 2010-04-28 2011-11-03 Chetan Balar Composition comprising chitin and tinosporin for use in the treatment of viral diseases
WO2013059572A1 (en) 2011-10-19 2013-04-25 Assia Chemical Industries Ltd. Process for the preparation of etravirine and intermediates in the synthesis thereof
BR112022016342A2 (pt) 2020-02-19 2022-10-04 Pharmasyntez Biciclos à base de pirimidina como agentes antivirais para o tratamento e prevenção da infecção por hiv

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459731A (en) * 1966-12-16 1969-08-05 Corn Products Co Cyclodextrin polyethers and their production
CZ154398A3 (cs) 1995-11-23 1998-08-12 Janssen Pharmaceutica N.V. Pevné směsi cyklodextrinů připravené vytlačováním taveniny
CZ301367B6 (cs) * 1998-11-10 2010-02-03 Janssen Pharmaceutica N. V. Derivát pyrimidinu, zpusob a meziprodukty pro jeho prípravu a lécivo pro lécení HIV na jeho bázi
AU775360B2 (en) * 1999-09-24 2004-07-29 Janssen Pharmaceutica N.V. Antiviral compositions
EP1282607B1 (en) * 2000-05-08 2015-11-11 Janssen Pharmaceutica NV Prodrugs of hiv replication inhibiting pyrimidines

Also Published As

Publication number Publication date
EP1858861B1 (en) 2010-07-07
ME01229B (me) 2013-06-20
WO2006094930A1 (en) 2006-09-14
AU2006222057A1 (en) 2006-09-14
BRPI0609291A2 (pt) 2010-03-09
BRPI0609291B1 (pt) 2022-02-08
US8119801B2 (en) 2012-02-21
ATE473212T1 (de) 2010-07-15
CY1111102T1 (el) 2015-06-11
JP2008531658A (ja) 2008-08-14
MX2007010744A (es) 2007-09-12
RU2007136782A (ru) 2009-04-10
ES2347815T3 (es) 2010-11-04
DK1858861T3 (da) 2010-11-08
EP1858861A1 (en) 2007-11-28
CN101133038A (zh) 2008-02-27
PT1858861E (pt) 2010-09-16
US20080214588A1 (en) 2008-09-04
CN101133038B (zh) 2012-06-27
RS51435B (en) 2011-04-30
RU2401261C2 (ru) 2010-10-10
SI1858861T1 (sl) 2010-10-29
JP5118978B2 (ja) 2013-01-16
DE602006015291D1 (de) 2010-08-19
US20100121060A1 (en) 2010-05-13
AU2006222057B2 (en) 2012-10-04
HRP20100504T1 (hr) 2010-10-31

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