PL1638539T3 - Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy - Google Patents

Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy

Info

Publication number
PL1638539T3
PL1638539T3 PL04727195T PL04727195T PL1638539T3 PL 1638539 T3 PL1638539 T3 PL 1638539T3 PL 04727195 T PL04727195 T PL 04727195T PL 04727195 T PL04727195 T PL 04727195T PL 1638539 T3 PL1638539 T3 PL 1638539T3
Authority
PL
Poland
Prior art keywords
pharmaceutical compositions
block copolymers
poly
alkyl
hydrophobic drug
Prior art date
Application number
PL04727195T
Other languages
English (en)
Inventor
Vinayak Sant
Jean-Christophe Leroux
Original Assignee
Univ Montreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Montreal filed Critical Univ Montreal
Publication of PL1638539T3 publication Critical patent/PL1638539T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02Polyalkylene oxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
PL04727195T 2003-06-25 2004-04-14 Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy PL1638539T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/607,446 US7094810B2 (en) 2001-06-08 2003-06-25 pH-sensitive block copolymers for pharmaceutical compositions
EP04727195A EP1638539B1 (en) 2003-06-25 2004-04-14 Pharmaceutical compositions comprising ph-sensitive block copolymers and a hydrophobic drug
PCT/CA2004/000561 WO2004112757A1 (en) 2003-06-25 2004-04-14 Pharmaceutical compositions comprising ph-sensitive block copolymers and a hydrophobic drug

Publications (1)

Publication Number Publication Date
PL1638539T3 true PL1638539T3 (pl) 2009-10-30

Family

ID=33540273

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04727195T PL1638539T3 (pl) 2003-06-25 2004-04-14 Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy

Country Status (16)

Country Link
US (1) US7094810B2 (pl)
EP (1) EP1638539B1 (pl)
JP (1) JP4619357B2 (pl)
AT (1) ATE418970T1 (pl)
AU (1) AU2004248863B2 (pl)
BR (1) BRPI0411872A (pl)
CA (1) CA2530736C (pl)
CY (1) CY1110264T1 (pl)
DE (1) DE602004018772D1 (pl)
DK (1) DK1638539T3 (pl)
ES (1) ES2323701T3 (pl)
MX (1) MXPA05014017A (pl)
PL (1) PL1638539T3 (pl)
PT (1) PT1638539E (pl)
SI (1) SI1638539T1 (pl)
WO (1) WO2004112757A1 (pl)

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CA2698812A1 (en) * 2007-09-14 2009-03-19 Nitto Denko Corporation Drug carriers
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US8778400B2 (en) * 2008-04-21 2014-07-15 University Of South Australia Nanoparticle-stabilized capsule formulation for treatment of inflammation
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EP3027221A1 (en) 2013-07-30 2016-06-08 PhaseRx, Inc. Block copolymers and their conjugates or complexes with oligonucleotides
US11219634B2 (en) 2015-01-21 2022-01-11 Genevant Sciences Gmbh Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells
WO2017156183A1 (en) 2016-03-08 2017-09-14 Los Gatos Pharmaceuticals, Inc. Camptothecin derivatives and uses thereof
JP2019510085A (ja) 2016-03-08 2019-04-11 ロス ガトス ファーマスーティカルズ, インク.Los Gatos Pharmaceuticals, Inc. 癌治療のためのナノ粒子ならびに方法および化合物
CN106432647B (zh) * 2016-09-26 2018-10-30 华南理工大学 基于叔氨基的pH响应嵌段聚合物及其混合胶束与应用
US11684584B2 (en) 2016-12-30 2023-06-27 Genevant Sciences Gmbh Branched peg molecules and related compositions and methods
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CN114377144A (zh) * 2022-01-28 2022-04-22 南通大学 pH/活性氧双重响应性超分子聚肽前药纳米粒子

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Also Published As

Publication number Publication date
CY1110264T1 (el) 2015-01-14
US20040072784A1 (en) 2004-04-15
EP1638539B1 (en) 2008-12-31
DE602004018772D1 (de) 2009-02-12
WO2004112757A1 (en) 2004-12-29
JP4619357B2 (ja) 2011-01-26
ATE418970T1 (de) 2009-01-15
JP2007505029A (ja) 2007-03-08
CA2530736C (en) 2013-07-02
SI1638539T1 (sl) 2009-10-31
MXPA05014017A (es) 2007-01-31
EP1638539A1 (en) 2006-03-29
AU2004248863B2 (en) 2009-03-12
AU2004248863A1 (en) 2004-12-29
ES2323701T3 (es) 2009-07-23
CA2530736A1 (en) 2004-12-29
PT1638539E (pt) 2009-04-09
DK1638539T3 (da) 2009-05-04
BRPI0411872A (pt) 2006-08-08
US7094810B2 (en) 2006-08-22

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