WO2004078111A3 - Extended release minocycline compositions and processes for their preparation - Google Patents

Extended release minocycline compositions and processes for their preparation Download PDF

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Publication number
WO2004078111A3
WO2004078111A3 PCT/IB2004/000631 IB2004000631W WO2004078111A3 WO 2004078111 A3 WO2004078111 A3 WO 2004078111A3 IB 2004000631 W IB2004000631 W IB 2004000631W WO 2004078111 A3 WO2004078111 A3 WO 2004078111A3
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WO
Grant status
Application
Patent type
Prior art keywords
minocycline
extended release
preparation
processes
demethyltetracycline
Prior art date
Application number
PCT/IB2004/000631
Other languages
French (fr)
Other versions
WO2004078111A2 (en )
Inventor
Prashant Manohar Mandaogade
Rajeev Singh Raghuvanshi
Ashok Rampal
Original Assignee
Prashant Manohar Mandaogade
Rajeev Singh Raghuvanshi
Ashok Rampal
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

The present invention relates to extended or controlled release pharmaceutical compositions of 7-dimethylamino-6-deoxy-6-demethyltetracycline (minocycline) or non-toxic acid addition salts thereof. More particularly, it relates to a once-a-day delivery system for minocycline that maintains its therapeutic plasma concentrations in a patient for twenty-four hours. The extended release pharmaceutical composition includes a mixture of 7-dimethylamino-6-deoxy-6-demethyltetracycline (minocycline), or a non-toxic acid addition salt thereof, and two or more hydrophilic matrix forming polymers configured to form a matrix upon administration. Each hydrophilic matrix forming polymer differs at least in viscosity.
PCT/IB2004/000631 2003-03-06 2004-03-08 Extended release minocycline compositions and processes for their preparation WO2004078111A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IN235/DEL/2003 2003-03-06
IN235DE2003 2003-03-06

Publications (2)

Publication Number Publication Date
WO2004078111A2 true WO2004078111A2 (en) 2004-09-16
WO2004078111A3 true true WO2004078111A3 (en) 2004-10-28

Family

ID=32948048

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/000631 WO2004078111A3 (en) 2003-03-06 2004-03-08 Extended release minocycline compositions and processes for their preparation

Country Status (1)

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WO (1) WO2004078111A3 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1858488B1 (en) 2005-03-14 2013-09-11 Wyeth LLC Tigecycline compositions and methods of preparation
US7919483B2 (en) 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
GB0703909D0 (en) * 2007-02-28 2007-04-11 Neuropharm Ltd Treatment of anxiety disorders
US7541347B2 (en) 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080242642A1 (en) 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7544373B2 (en) 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
WO2010017310A1 (en) 2008-08-06 2010-02-11 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
CN104606171A (en) * 2015-02-04 2015-05-13 上海华源安徽仁济制药有限公司 Minocycline hydrochloride capsule and preparation method thereof
WO2016162754A1 (en) 2015-04-07 2016-10-13 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions for minocycline

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5277916A (en) * 1988-02-01 1994-01-11 F. H. Faulding & Co., Ltd. Tetracycline dosage form
WO2000038650A1 (en) * 1998-12-23 2000-07-06 Alza Corporation Gastric retention dosage form having multiple layers
US20030017189A1 (en) * 1998-12-23 2003-01-23 Patrick S.-L. Wong Gastric retaining oral liquid dosage form

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5277916A (en) * 1988-02-01 1994-01-11 F. H. Faulding & Co., Ltd. Tetracycline dosage form
WO2000038650A1 (en) * 1998-12-23 2000-07-06 Alza Corporation Gastric retention dosage form having multiple layers
US20030017189A1 (en) * 1998-12-23 2003-01-23 Patrick S.-L. Wong Gastric retaining oral liquid dosage form

Also Published As

Publication number Publication date Type
WO2004078111A2 (en) 2004-09-16 application

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