PL1636223T3 - Pochodne benzotiazolu jako ligandy receptora adenozynowego - Google Patents
Pochodne benzotiazolu jako ligandy receptora adenozynowegoInfo
- Publication number
- PL1636223T3 PL1636223T3 PL04732950T PL04732950T PL1636223T3 PL 1636223 T3 PL1636223 T3 PL 1636223T3 PL 04732950 T PL04732950 T PL 04732950T PL 04732950 T PL04732950 T PL 04732950T PL 1636223 T3 PL1636223 T3 PL 1636223T3
- Authority
- PL
- Poland
- Prior art keywords
- receptor ligands
- adenosine receptor
- benzothiazole derivatives
- benzothiazole
- derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03011039 | 2003-05-19 | ||
| EP04732950A EP1636223B1 (en) | 2003-05-19 | 2004-05-14 | Benzothiazole derivatives as adenosine receptor ligands |
| PCT/EP2004/005178 WO2005000842A1 (en) | 2003-05-19 | 2004-05-14 | Benzothiazole derivatives as adenosine receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1636223T3 true PL1636223T3 (pl) | 2008-07-31 |
Family
ID=33442729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04732950T PL1636223T3 (pl) | 2003-05-19 | 2004-05-14 | Pochodne benzotiazolu jako ligandy receptora adenozynowego |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7371748B2 (pl) |
| EP (1) | EP1636223B1 (pl) |
| JP (1) | JP4444290B2 (pl) |
| KR (1) | KR100859886B1 (pl) |
| CN (1) | CN100528871C (pl) |
| AR (1) | AR044362A1 (pl) |
| AT (1) | ATE389652T1 (pl) |
| AU (1) | AU2004251814B2 (pl) |
| BR (1) | BRPI0410440A (pl) |
| CA (1) | CA2524366C (pl) |
| CL (1) | CL2004001067A1 (pl) |
| CO (1) | CO5630031A2 (pl) |
| DE (1) | DE602004012555T2 (pl) |
| DK (1) | DK1636223T3 (pl) |
| ES (1) | ES2301991T3 (pl) |
| HK (1) | HK1092469A1 (pl) |
| HR (1) | HRP20080207T3 (pl) |
| IL (1) | IL171686A (pl) |
| MX (1) | MXPA05012360A (pl) |
| NO (1) | NO20055150L (pl) |
| NZ (1) | NZ543074A (pl) |
| PL (1) | PL1636223T3 (pl) |
| PT (1) | PT1636223E (pl) |
| RU (1) | RU2351597C2 (pl) |
| SI (1) | SI1636223T1 (pl) |
| TW (1) | TW200505882A (pl) |
| WO (1) | WO2005000842A1 (pl) |
| ZA (1) | ZA200509294B (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008052930A2 (en) * | 2006-11-03 | 2008-05-08 | F. Hoffmann-La Roche Ag | Preparation of 4-alk0xy-7- (tetrahydropyran-4-yl) benzothiazol-2-amine derivatives |
| DK3661941T3 (da) | 2017-08-01 | 2023-03-13 | Merck Patent Gmbh | Thiazolopyridinderivater som adenosinreceptor-antagonister |
| TW201920123A (zh) * | 2017-08-21 | 2019-06-01 | 德商馬克專利公司 | 作為腺苷受體拮抗劑之喹㗁啉衍生物 |
| SG11202001337XA (en) | 2017-08-21 | 2020-03-30 | Merck Patent Gmbh | Bezimidazole derivatives as adenosine receptor antagonists |
| WO2019141096A1 (zh) * | 2018-01-19 | 2019-07-25 | 四川科伦博泰生物医药股份有限公司 | 取代脲类化合物及其制备方法和用途 |
| CN112867715B (zh) | 2018-10-25 | 2024-03-05 | 默克专利股份公司 | 作为腺苷受体拮抗剂的5-氮杂吲唑衍生物 |
| BR112021007727A2 (pt) | 2018-10-25 | 2021-07-27 | Merck Patent Gmbh | derivados de 5-azaindazol como antagonistas receptores de adenosina |
| AR117844A1 (es) * | 2019-01-22 | 2021-09-01 | Merck Patent Gmbh | Derivados de tiazolopiridina como antagonistas del receptor de adenosina |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE385794T1 (de) * | 2000-06-21 | 2008-03-15 | Hoffmann La Roche | Benzothiazolderivate zur behandlung von alzheimer und parkinson |
| BR0214455A (pt) * | 2001-11-27 | 2004-11-03 | Hoffmann La Roche | Derivados benzotiazol |
| US6727247B2 (en) * | 2001-12-10 | 2004-04-27 | Hoffman-La Roche Inc. | Substituted benzothiazole amide derivatives |
| US6734179B2 (en) * | 2001-12-12 | 2004-05-11 | Hoffmann-La Roche Inc. | Benzothiazoles |
| BRPI0406747A (pt) * | 2003-01-13 | 2005-12-20 | Hoffmann La Roche | Derivados de benzoxazol e seu uso como ligandos de receptor de adenosina |
-
2004
- 2004-05-14 CN CNB2004800135624A patent/CN100528871C/zh not_active Expired - Fee Related
- 2004-05-14 EP EP04732950A patent/EP1636223B1/en not_active Expired - Lifetime
- 2004-05-14 TW TW093113590A patent/TW200505882A/zh unknown
- 2004-05-14 AT AT04732950T patent/ATE389652T1/de active
- 2004-05-14 MX MXPA05012360A patent/MXPA05012360A/es active IP Right Grant
- 2004-05-14 PT PT04732950T patent/PT1636223E/pt unknown
- 2004-05-14 DK DK04732950T patent/DK1636223T3/da active
- 2004-05-14 DE DE602004012555T patent/DE602004012555T2/de not_active Expired - Lifetime
- 2004-05-14 NZ NZ543074A patent/NZ543074A/en unknown
- 2004-05-14 WO PCT/EP2004/005178 patent/WO2005000842A1/en active IP Right Grant
- 2004-05-14 RU RU2005139527/04A patent/RU2351597C2/ru not_active IP Right Cessation
- 2004-05-14 BR BRPI0410440-4A patent/BRPI0410440A/pt not_active Application Discontinuation
- 2004-05-14 JP JP2006529816A patent/JP4444290B2/ja not_active Expired - Fee Related
- 2004-05-14 CA CA2524366A patent/CA2524366C/en not_active Expired - Fee Related
- 2004-05-14 KR KR1020057021945A patent/KR100859886B1/ko active IP Right Grant
- 2004-05-14 ES ES04732950T patent/ES2301991T3/es not_active Expired - Lifetime
- 2004-05-14 PL PL04732950T patent/PL1636223T3/pl unknown
- 2004-05-14 AU AU2004251814A patent/AU2004251814B2/en not_active Ceased
- 2004-05-14 SI SI200430668T patent/SI1636223T1/sl unknown
- 2004-05-17 CL CL200401067A patent/CL2004001067A1/es unknown
- 2004-05-17 AR ARP040101684A patent/AR044362A1/es not_active Application Discontinuation
- 2004-05-17 US US10/847,558 patent/US7371748B2/en not_active Expired - Fee Related
-
2005
- 2005-10-31 IL IL171686A patent/IL171686A/en active IP Right Grant
- 2005-11-03 NO NO20055150A patent/NO20055150L/no not_active Application Discontinuation
- 2005-11-16 ZA ZA200509294A patent/ZA200509294B/en unknown
- 2005-11-16 CO CO05116289A patent/CO5630031A2/es not_active Application Discontinuation
-
2006
- 2006-11-29 HK HK06113066.6A patent/HK1092469A1/xx not_active IP Right Cessation
-
2008
- 2008-05-08 HR HR20080207T patent/HRP20080207T3/xx unknown
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