CL2004001067A1 - Compuestos derivados de benzotiazol; procedimiento de preparacion; medicamentos que los contiene; y su uso en el tratamiento de enfermedades relacionadas con el receptor de adenosina a2a. - Google Patents
Compuestos derivados de benzotiazol; procedimiento de preparacion; medicamentos que los contiene; y su uso en el tratamiento de enfermedades relacionadas con el receptor de adenosina a2a.Info
- Publication number
- CL2004001067A1 CL2004001067A1 CL200401067A CL2004001067A CL2004001067A1 CL 2004001067 A1 CL2004001067 A1 CL 2004001067A1 CL 200401067 A CL200401067 A CL 200401067A CL 2004001067 A CL2004001067 A CL 2004001067A CL 2004001067 A1 CL2004001067 A1 CL 2004001067A1
- Authority
- CL
- Chile
- Prior art keywords
- benzotiazol
- treatment
- diseases related
- preparation procedure
- compounds derived
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03011039 | 2003-05-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2004001067A1 true CL2004001067A1 (es) | 2005-04-15 |
Family
ID=33442729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200401067A CL2004001067A1 (es) | 2003-05-19 | 2004-05-17 | Compuestos derivados de benzotiazol; procedimiento de preparacion; medicamentos que los contiene; y su uso en el tratamiento de enfermedades relacionadas con el receptor de adenosina a2a. |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7371748B2 (es) |
| EP (1) | EP1636223B1 (es) |
| JP (1) | JP4444290B2 (es) |
| KR (1) | KR100859886B1 (es) |
| CN (1) | CN100528871C (es) |
| AR (1) | AR044362A1 (es) |
| AT (1) | ATE389652T1 (es) |
| AU (1) | AU2004251814B2 (es) |
| BR (1) | BRPI0410440A (es) |
| CA (1) | CA2524366C (es) |
| CL (1) | CL2004001067A1 (es) |
| CO (1) | CO5630031A2 (es) |
| DE (1) | DE602004012555T2 (es) |
| DK (1) | DK1636223T3 (es) |
| ES (1) | ES2301991T3 (es) |
| HK (1) | HK1092469A1 (es) |
| HR (1) | HRP20080207T3 (es) |
| IL (1) | IL171686A (es) |
| MX (1) | MXPA05012360A (es) |
| NO (1) | NO20055150L (es) |
| NZ (1) | NZ543074A (es) |
| PL (1) | PL1636223T3 (es) |
| PT (1) | PT1636223E (es) |
| RU (1) | RU2351597C2 (es) |
| SI (1) | SI1636223T1 (es) |
| TW (1) | TW200505882A (es) |
| WO (1) | WO2005000842A1 (es) |
| ZA (1) | ZA200509294B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008052930A2 (en) * | 2006-11-03 | 2008-05-08 | F. Hoffmann-La Roche Ag | Preparation of 4-alk0xy-7- (tetrahydropyran-4-yl) benzothiazol-2-amine derivatives |
| IL272284B2 (en) | 2017-08-01 | 2024-01-01 | Merck Patent Gmbh | History of thiazolopyridines, their preparation and pharmaceutical preparations containing them |
| JP7287952B2 (ja) | 2017-08-21 | 2023-06-06 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | アデノシン受容体アンタゴニストとしてのベンズイミダゾール誘導体 |
| WO2019038214A1 (en) | 2017-08-21 | 2019-02-28 | Merck Patent Gmbh | QUINOXALINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS |
| WO2019141096A1 (zh) * | 2018-01-19 | 2019-07-25 | 四川科伦博泰生物医药股份有限公司 | 取代脲类化合物及其制备方法和用途 |
| CN112867715B (zh) | 2018-10-25 | 2024-03-05 | 默克专利股份公司 | 作为腺苷受体拮抗剂的5-氮杂吲唑衍生物 |
| KR20210083293A (ko) | 2018-10-25 | 2021-07-06 | 메르크 파텐트 게엠베하 | 아데노신 수용체 안타고니스트로서의 5-아자인다졸 유도체 |
| AR117844A1 (es) | 2019-01-22 | 2021-09-01 | Merck Patent Gmbh | Derivados de tiazolopiridina como antagonistas del receptor de adenosina |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1234358C (zh) * | 2000-06-21 | 2006-01-04 | 弗·哈夫曼-拉罗切有限公司 | 苯并噻唑衍生物 |
| EP1450796B1 (en) * | 2001-11-27 | 2008-04-09 | F. Hoffmann-La Roche Ag | Benzothiazole derivatives |
| US6727247B2 (en) * | 2001-12-10 | 2004-04-27 | Hoffman-La Roche Inc. | Substituted benzothiazole amide derivatives |
| US6734179B2 (en) * | 2001-12-12 | 2004-05-11 | Hoffmann-La Roche Inc. | Benzothiazoles |
| PL378343A1 (pl) * | 2003-01-13 | 2006-03-20 | F. Hoffmann-La Roche Ag | Pochodne benzoksazolu i ich zastosowanie jako ligandów receptora adenozyny |
-
2004
- 2004-05-14 PT PT04732950T patent/PT1636223E/pt unknown
- 2004-05-14 SI SI200430668T patent/SI1636223T1/sl unknown
- 2004-05-14 EP EP04732950A patent/EP1636223B1/en not_active Expired - Lifetime
- 2004-05-14 AT AT04732950T patent/ATE389652T1/de active
- 2004-05-14 WO PCT/EP2004/005178 patent/WO2005000842A1/en active IP Right Grant
- 2004-05-14 BR BRPI0410440-4A patent/BRPI0410440A/pt not_active Application Discontinuation
- 2004-05-14 NZ NZ543074A patent/NZ543074A/en unknown
- 2004-05-14 JP JP2006529816A patent/JP4444290B2/ja not_active Expired - Fee Related
- 2004-05-14 KR KR1020057021945A patent/KR100859886B1/ko active IP Right Grant
- 2004-05-14 DK DK04732950T patent/DK1636223T3/da active
- 2004-05-14 RU RU2005139527/04A patent/RU2351597C2/ru not_active IP Right Cessation
- 2004-05-14 ES ES04732950T patent/ES2301991T3/es not_active Expired - Lifetime
- 2004-05-14 AU AU2004251814A patent/AU2004251814B2/en not_active Ceased
- 2004-05-14 DE DE602004012555T patent/DE602004012555T2/de not_active Expired - Lifetime
- 2004-05-14 TW TW093113590A patent/TW200505882A/zh unknown
- 2004-05-14 MX MXPA05012360A patent/MXPA05012360A/es active IP Right Grant
- 2004-05-14 CN CNB2004800135624A patent/CN100528871C/zh not_active Expired - Fee Related
- 2004-05-14 PL PL04732950T patent/PL1636223T3/pl unknown
- 2004-05-14 CA CA2524366A patent/CA2524366C/en not_active Expired - Fee Related
- 2004-05-17 AR ARP040101684A patent/AR044362A1/es not_active Application Discontinuation
- 2004-05-17 CL CL200401067A patent/CL2004001067A1/es unknown
- 2004-05-17 US US10/847,558 patent/US7371748B2/en not_active Expired - Fee Related
-
2005
- 2005-10-31 IL IL171686A patent/IL171686A/en active IP Right Grant
- 2005-11-03 NO NO20055150A patent/NO20055150L/no not_active Application Discontinuation
- 2005-11-16 ZA ZA200509294A patent/ZA200509294B/en unknown
- 2005-11-16 CO CO05116289A patent/CO5630031A2/es not_active Application Discontinuation
-
2006
- 2006-11-29 HK HK06113066.6A patent/HK1092469A1/xx not_active IP Right Cessation
-
2008
- 2008-05-08 HR HR20080207T patent/HRP20080207T3/xx unknown
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