ZA200703005B - Preparation of 2'Fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives - Google Patents

Preparation of 2'Fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives

Info

Publication number
ZA200703005B
ZA200703005B ZA200703005A ZA200703005A ZA200703005B ZA 200703005 B ZA200703005 B ZA 200703005B ZA 200703005 A ZA200703005 A ZA 200703005A ZA 200703005 A ZA200703005 A ZA 200703005A ZA 200703005 B ZA200703005 B ZA 200703005B
Authority
ZA
South Africa
Prior art keywords
substituted
purines
fluoro
derivatives
alkyl
Prior art date
Application number
ZA200703005A
Inventor
Byoung-Kwon Chun
Peiyuan Wang
Jinfa Du
Suguna Rachakonda
Original Assignee
Pharmasset Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmasset Inc filed Critical Pharmasset Inc
Publication of ZA200703005B publication Critical patent/ZA200703005B/en

Links

ZA200703005A 2004-09-14 2007-04-12 Preparation of 2'Fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives ZA200703005B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60978304P 2004-09-14 2004-09-14

Publications (1)

Publication Number Publication Date
ZA200703005B true ZA200703005B (en) 2009-12-30

Family

ID=40711560

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200703005A ZA200703005B (en) 2004-09-14 2007-04-12 Preparation of 2'Fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives

Country Status (2)

Country Link
CN (1) CN101437524B (en)
ZA (1) ZA200703005B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5716500B2 (en) * 2010-06-03 2015-05-13 セントラル硝子株式会社 Method for producing (2R) -2-fluoro-2-C-methyl-D-ribono-γ-lactone precursors
EP2909209B1 (en) * 2012-10-17 2022-08-03 Merck Sharp & Dohme LLC 2'-cyano substituted nucleoside derivatives and methods of use thereof for treatment of viral diseases
EP2909210A4 (en) * 2012-10-17 2016-04-06 Merck Sharp & Dohme 2'-disubstituted substituted nucleoside derivatives and methods of use thereof for treatment of viral diseases
WO2014132975A1 (en) * 2013-02-28 2014-09-04 セントラル硝子株式会社 Method of producing (2r)-2-fluoro-2-c-methyl-d-ribono-γ-lactone
CN104558079B (en) * 2015-01-30 2017-06-16 南京正大天晴制药有限公司 A kind of high-purity rope fluorine cloth Wei compound and the preparation method about material
CN104987355A (en) * 2015-07-10 2015-10-21 上海同昌生物医药科技有限公司 Synthesis method of intermediate compound of sofosbuvir
CN105218607A (en) * 2015-09-16 2016-01-06 重庆康施恩化工有限公司 Anti-hepatitis C virus medicine rope fluorine cloth Wei Intermediate Preparation method
CN106608896B (en) * 2015-10-26 2019-08-27 江苏福瑞康泰药业有限公司 A kind of synthetic method of pharmaceutical intermediate
JOP20190024A1 (en) * 2016-08-26 2019-02-19 Gilead Sciences Inc Substituted pyrrolizine compounds and uses thereof
CN107200757B (en) * 2017-06-29 2020-06-02 上海泓博智源医药股份有限公司 Bridged fluorinated ester and preparation method and application thereof
CN108373460B (en) * 2018-03-27 2019-10-15 上海康鹏科技股份有限公司 A kind of preparation method of cyclic sulfates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR900016822A (en) * 1990-04-20 1990-11-14 하라 레이노스께 Slide projector
US5426183A (en) * 1992-06-22 1995-06-20 Eli Lilly And Company Catalytic stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
ATE153669T1 (en) * 1992-06-22 1997-06-15 Lilly Co Eli METHOD FOR PRODUCING 1-HALOGEN-2-DEOXY-2,2-DIFLUOR-D-RIBOFURANOSYL DERIVATIVES ENRICHED WITH ALPHA-ANOMERS

Also Published As

Publication number Publication date
CN101437524A (en) 2009-05-20
CN101437524B (en) 2012-01-11

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