BRPI0406747A - Derivados de benzoxazol e seu uso como ligandos de receptor de adenosina - Google Patents
Derivados de benzoxazol e seu uso como ligandos de receptor de adenosinaInfo
- Publication number
- BRPI0406747A BRPI0406747A BR0406747-9A BRPI0406747A BRPI0406747A BR PI0406747 A BRPI0406747 A BR PI0406747A BR PI0406747 A BRPI0406747 A BR PI0406747A BR PI0406747 A BRPI0406747 A BR PI0406747A
- Authority
- BR
- Brazil
- Prior art keywords
- sub
- halogen
- receptor ligands
- adenosine receptor
- och
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
"DERIVADOS DE BENZOXAZOL E SEU USO COMO LIGANDOS DE RECEPTOR DE ADENOSINA". A presente invenção refere-se a compostos da fórmula (I) em que R é fenila, não-substituída ou substituída por halogênio ou -CH~ 2~N(CH~ 3~)(CH~ 2~)~ n~OCH~ 3~, ou é benzila, alquila inferior, alcóxi inferior, -(CH~ 2~)~ n~OCH~ 3~, ou é piridin 3- ou 4-ila, não-substituída ou substituída por alquila inferior, halogênio, morfolinila, -(CH~ 2~)~ n~-halogênio, -(CH~ 2~)~ n~OCH~ 3~, -(CH~ 2~)~ n~-morfolin-4-ila, ou -(CH~ 2~)~ n~pirrolidin-1-ila; R¬ 1¬ é fenila, não-substituída ou substituída por halogênio, tetraldropiran-4-ila, 3,6-diidro-2H-piran-4-ila ou morfolin-4-ila; n é independentemente um do outro 1 ou 2; e a sais de adição de ácido farmaceuticamente aceitáveis dos mesmos para o tratamento de doenças relacionadas ao receptor A~ 2A~ de adenosina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03000558 | 2003-01-13 | ||
| PCT/EP2004/000053 WO2004063177A1 (en) | 2003-01-13 | 2004-01-08 | Benzoxazole derivatives and their use as adenosine receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0406747A true BRPI0406747A (pt) | 2005-12-20 |
Family
ID=32695588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0406747-9A BRPI0406747A (pt) | 2003-01-13 | 2004-01-08 | Derivados de benzoxazol e seu uso como ligandos de receptor de adenosina |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6992083B2 (pt) |
| EP (1) | EP1587799B1 (pt) |
| JP (1) | JP4390772B2 (pt) |
| KR (1) | KR100699615B1 (pt) |
| CN (1) | CN100406446C (pt) |
| AT (1) | ATE388945T1 (pt) |
| BR (1) | BRPI0406747A (pt) |
| CA (1) | CA2512602A1 (pt) |
| DE (1) | DE602004012388T2 (pt) |
| ES (1) | ES2301962T3 (pt) |
| MX (1) | MXPA05007388A (pt) |
| PL (1) | PL378343A1 (pt) |
| RU (1) | RU2334742C2 (pt) |
| WO (1) | WO2004063177A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ543074A (en) * | 2003-05-19 | 2009-01-31 | Hoffmann La Roche | Benzothiazole derivatives as adenosine receptor ligands |
| WO2005016267A2 (en) * | 2003-08-06 | 2005-02-24 | Pfizer Products Inc. | Oxazole compounds for the treatment of neurodegenerative disorders |
| KR100703598B1 (ko) * | 2005-07-07 | 2007-04-06 | 한국생명공학연구원 | 리폭시제나아제에 대한 저해 활성을 갖는 신규벤즈옥사졸 아미드 유도체 화합물, 이의 제조방법 및 이를포함하는 천식의 치료 및 예방용 조성물 |
| KR20080027191A (ko) * | 2006-09-22 | 2008-03-26 | 이화여자대학교 산학협력단 | 신규한 벤즈옥사졸 유도체, 이의 제조방법 및 이를포함하는 약학 조성물 |
| GB0622826D0 (en) * | 2006-11-15 | 2006-12-27 | Acurepharma Ab | Novel amides acting on the adenosine receptors |
| DE102011005232A1 (de) | 2011-03-08 | 2012-09-13 | AristoCon GmbH & Co. KG | Adenosin und seine Derivate zur Verwendung in der Schmerztherapie |
| CN103772376B (zh) * | 2012-10-24 | 2017-01-11 | 中国医学科学院医药生物技术研究所 | 取代的苯并-1,3-杂唑类化合物、其制备方法及用途 |
| KR102064611B1 (ko) * | 2017-10-13 | 2020-01-09 | 이화여자대학교 산학협력단 | 벤즈옥사졸 유도체, 이의 제조 방법 및 이를 포함하는 약학적 조성물 |
| WO2021100889A1 (ko) * | 2019-11-18 | 2021-05-27 | 경희대학교 산학협력단 | 신규 화합물을 처리한 줄기세포를 포함하는 척수손상 치료용 조성물 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ522928A (en) * | 2000-06-21 | 2005-05-27 | F | Benzothiazole derivatives |
| US6734179B2 (en) * | 2001-12-12 | 2004-05-11 | Hoffmann-La Roche Inc. | Benzothiazoles |
-
2004
- 2004-01-08 MX MXPA05007388A patent/MXPA05007388A/es active IP Right Grant
- 2004-01-08 WO PCT/EP2004/000053 patent/WO2004063177A1/en active IP Right Grant
- 2004-01-08 DE DE602004012388T patent/DE602004012388T2/de not_active Expired - Lifetime
- 2004-01-08 CA CA002512602A patent/CA2512602A1/en not_active Abandoned
- 2004-01-08 RU RU2005125636/04A patent/RU2334742C2/ru not_active IP Right Cessation
- 2004-01-08 EP EP04700671A patent/EP1587799B1/en not_active Expired - Lifetime
- 2004-01-08 JP JP2005518637A patent/JP4390772B2/ja not_active Expired - Fee Related
- 2004-01-08 ES ES04700671T patent/ES2301962T3/es not_active Expired - Lifetime
- 2004-01-08 KR KR1020057012911A patent/KR100699615B1/ko not_active IP Right Cessation
- 2004-01-08 PL PL378343A patent/PL378343A1/pl not_active Application Discontinuation
- 2004-01-08 AT AT04700671T patent/ATE388945T1/de not_active IP Right Cessation
- 2004-01-08 BR BR0406747-9A patent/BRPI0406747A/pt not_active IP Right Cessation
- 2004-01-08 CN CNB2004800019619A patent/CN100406446C/zh not_active Expired - Fee Related
- 2004-01-09 US US10/755,105 patent/US6992083B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| RU2334742C2 (ru) | 2008-09-27 |
| KR100699615B1 (ko) | 2007-03-23 |
| WO2004063177A1 (en) | 2004-07-29 |
| MXPA05007388A (es) | 2005-09-12 |
| ATE388945T1 (de) | 2008-03-15 |
| CN100406446C (zh) | 2008-07-30 |
| RU2005125636A (ru) | 2006-03-20 |
| CN1723204A (zh) | 2006-01-18 |
| JP2006516270A (ja) | 2006-06-29 |
| JP4390772B2 (ja) | 2009-12-24 |
| PL378343A1 (pl) | 2006-03-20 |
| AU2004203909A1 (en) | 2004-07-29 |
| ES2301962T3 (es) | 2008-07-01 |
| DE602004012388D1 (de) | 2008-04-24 |
| AU2004203909B2 (en) | 2009-01-29 |
| DE602004012388T2 (de) | 2009-03-12 |
| EP1587799B1 (en) | 2008-03-12 |
| US20040152702A1 (en) | 2004-08-05 |
| KR20050099501A (ko) | 2005-10-13 |
| EP1587799A1 (en) | 2005-10-26 |
| US6992083B2 (en) | 2006-01-31 |
| CA2512602A1 (en) | 2004-07-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2348617C2 (ru) | Производные 2-пиридона в качестве ингибиторов эластазы нейтрофилов и их применение | |
| AR037418A1 (es) | Derivados de benzotiazol | |
| RU2005122901A (ru) | Производные пиридино [2,3-] пиримидина в качестве селективных ингибиторов kdr и fgfr | |
| BRPI0209216B8 (pt) | derivados de quinolina e de quinazolina, composições farmacêuticas compreendendo os mesmos e seus usos | |
| EA200701233A1 (ru) | Производные хиназолина в качестве mtki | |
| DE69614270D1 (de) | 5-azabicyclo(3.1.0.)hexylalkyl-2-piperidone und - glutarimide als neurokinin receptor antagonisten. | |
| NO20062491L (no) | Benzoksazinderivter og deres anvendelse | |
| ATE380818T1 (de) | Piperazine-substituierte aryl-benzodiazepinen und ihre verwendung als dopaminrezeptor-antagonisten zur behandlung von psychose | |
| BRPI0409110A (pt) | derivados de 4-(4-heterociclilalcoxi)fenil-1-(heterociclil-carboni l)piridina e compostos relacionados como antagonistas de histamina h3 para o tratamento de doenças neurológicas tais como alzheimer | |
| JP2008508359A5 (pt) | ||
| WO2007039781A3 (en) | 1,2,4-oxadioi.e derivatives with activity at the metabotropic clutamate receptors | |
| PE20070212A1 (es) | Heterociclos de 1,4-dihidropiridina-condensados, procesos para preparar los mismos, uso y composiciones que los contienen | |
| NO20022124L (no) | Imidazopyridinderivater som fosfodiesterase VII-inhibitorer | |
| BRPI0516381A (pt) | derivados de cromano e seu uso como ligandos de receptor de 5-ht | |
| BRPI0406747A (pt) | Derivados de benzoxazol e seu uso como ligandos de receptor de adenosina | |
| ATE338042T1 (de) | Hetero-bicyclische crf antagonisten | |
| AR041079A1 (es) | Derivados de 2-ariltiazol como agonistas de receptores activados proliferadores de peroxisomas alfa y gamma (ppar alfa y gamma) | |
| EA200500521A1 (ru) | 3-фенилзамещенный пиридоиндолон, его получение и терапевтическое применение | |
| AR039192A1 (es) | Derivados de diazabicicloalcano con actividad antagonista de nk1 | |
| MXPA02011464A (es) | Derivados 1,4-diazepan-2,5-diona y su uso como antagonistas del receptor de la nk-1. | |
| BR0213177A (pt) | Derivados de 5-metóxi-8-aril-[1,2,4]triazolo[1,5-a]piridina | |
| EA200401077A1 (ru) | 2-оксазоламины и их применение в качестве антагонистов рецептора 5-ht2b | |
| AR045548A1 (es) | Derivados de imidazol | |
| NO20070972L (no) | Benzyloksyderivater som MAOB-inhibitorer | |
| TW200505882A (en) | Benzothiazole derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |