PL161369B1 - Method of obtaining novel derivatives of 2-iminobenzothiazoline - Google Patents

Method of obtaining novel derivatives of 2-iminobenzothiazoline

Info

Publication number
PL161369B1
PL161369B1 PL1989285554A PL28555489A PL161369B1 PL 161369 B1 PL161369 B1 PL 161369B1 PL 1989285554 A PL1989285554 A PL 1989285554A PL 28555489 A PL28555489 A PL 28555489A PL 161369 B1 PL161369 B1 PL 161369B1
Authority
PL
Poland
Prior art keywords
formula
group
imino
mineral
compounds
Prior art date
Application number
PL1989285554A
Other languages
English (en)
Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8816546A external-priority patent/FR2640622B1/fr
Application filed filed Critical
Publication of PL161369B1 publication Critical patent/PL161369B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL1989285554A 1988-12-15 1989-12-14 Method of obtaining novel derivatives of 2-iminobenzothiazoline PL161369B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8816546A FR2640622B1 (fr) 1988-12-15 1988-12-15 Derives de l'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR898909480A FR2649701B2 (fr) 1988-12-15 1989-07-13 Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant

Publications (1)

Publication Number Publication Date
PL161369B1 true PL161369B1 (en) 1993-06-30

Family

ID=26227049

Family Applications (2)

Application Number Title Priority Date Filing Date
PL1989282766A PL161336B1 (pl) 1988-12-15 1989-12-14 S p o s ó b w y t w a r z a n i a n o w y c h p o c h o d n y c h 2 - im i n o b e n z o t ia z o l in y PL
PL1989285554A PL161369B1 (en) 1988-12-15 1989-12-14 Method of obtaining novel derivatives of 2-iminobenzothiazoline

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL1989282766A PL161336B1 (pl) 1988-12-15 1989-12-14 S p o s ó b w y t w a r z a n i a n o w y c h p o c h o d n y c h 2 - im i n o b e n z o t ia z o l in y PL

Country Status (22)

Country Link
US (1) US5008280A (en:Method)
EP (1) EP0374040B1 (en:Method)
JP (1) JPH0733376B2 (en:Method)
AU (1) AU618432B2 (en:Method)
CA (1) CA2005590A1 (en:Method)
CZ (1) CZ280107B6 (en:Method)
DE (1) DE68905585T2 (en:Method)
DK (1) DK169967B1 (en:Method)
ES (1) ES2054068T3 (en:Method)
FI (1) FI93106C (en:Method)
FR (1) FR2649701B2 (en:Method)
GR (1) GR3007788T3 (en:Method)
HU (1) HU203088B (en:Method)
IE (1) IE62714B1 (en:Method)
IL (1) IL92710A (en:Method)
NO (1) NO173060C (en:Method)
NZ (1) NZ231793A (en:Method)
PL (2) PL161336B1 (en:Method)
PT (1) PT92604B (en:Method)
RU (1) RU2037489C1 (en:Method)
SK (1) SK708189A3 (en:Method)
YU (1) YU47337B (en:Method)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2671081B1 (fr) * 1991-01-02 1994-09-30 Rhone Poulenc Rorer Sa Derives d'imino-2 polyfluoroalkyl-6 heterocyclylalkyl-3 benzothiazoline, leur preparation et les medicaments les contenant.
US5260297A (en) * 1989-07-13 1993-11-09 Rhone Poulenc Rorer, S.A. 2-imino-3-alkylbenzothiazoline derivatives bearing a heterocyclic substituent on the alkyl group, their preparation and medicinal products containing them.
FR2649702B1 (fr) * 1989-07-13 1991-11-22 Rhone Poulenc Sante Derives d'alkylimino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
DE69007196T2 (de) * 1989-07-13 1994-06-30 Rhone Poulenc Sante 2-Imino-3 heterocyclylamino-benzothiazoline, ihre Herstellung und sie enthaltende Arzneimittel.
US5240948A (en) * 1989-12-13 1993-08-31 Rhone-Poulenc Rorer Pharmaceuticals Inc. 3-(3-alkylthiopropyl)benzothiazoline derivatives, their preparation and the medicament containing them
FR2663029B1 (fr) * 1990-06-07 1992-07-31 Rhone Poulenc Sante Derives de benzothiazole, leur preparation et les medicaments les contenant.
FR2678619B1 (fr) * 1991-07-04 1993-09-17 Rhone Poulenc Rorer Sa Derives de 1,2,4-thiadiazolo[3,4-b]benzothiazole, leur preparation et les medicaments les contenant.
FR2726271B1 (fr) * 1994-10-26 1996-12-06 Rhone Poulenc Rorer Sa Derives de 6-polyfluoroalcoxy-2-aminobenzothiazole
FR2741804B1 (fr) * 1995-12-01 1998-01-02 Rhone Poulenc Rorer Sa Application de 2-iminobenzothiazolines dans le traitement de la maladie de parkinson et des syndromes parkinsoniens
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
CA2264043A1 (en) 1996-09-27 1998-04-02 Guilford Pharmaceuticals Inc. Naaladase compositions and methods for treating glutamate abnormality and effecting neuronal activity in animals
FR2766487B1 (fr) 1997-07-28 1999-08-27 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
AU4537500A (en) * 1999-05-12 2000-12-05 Neurosearch A/S Ion channel modulating agents
GB0307067D0 (en) 2002-12-17 2003-04-30 Aventis Pharma Inc Use of thiazolobenzoheterocycles for treating multiple sclerosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (de) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 2-Iminobenzothiazolen
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
US4918090A (en) * 1988-01-25 1990-04-17 Warner-Lambert Company Substituted 2-aminbenzothiazoles and derivatives useful as cerebrovascular agents

Also Published As

Publication number Publication date
IL92710A (en) 1993-06-10
FI895981A0 (fi) 1989-12-14
NO895030D0 (no) 1989-12-14
PT92604A (pt) 1990-06-29
DK633689A (da) 1990-06-16
IE62714B1 (en) 1995-02-22
US5008280A (en) 1991-04-16
IE894006L (en) 1990-06-15
EP0374040B1 (fr) 1993-03-24
CZ280107B6 (cs) 1995-10-18
HU203088B (en) 1991-05-28
SK278349B6 (en) 1997-01-08
IL92710A0 (en) 1990-09-17
NO173060B (no) 1993-07-12
DE68905585T2 (de) 1993-09-16
FI93106B (fi) 1994-11-15
EP0374040A1 (fr) 1990-06-20
JPH0733376B2 (ja) 1995-04-12
ES2054068T3 (es) 1994-08-01
PT92604B (pt) 1995-09-12
CZ708189A3 (en) 1995-06-14
YU236989A (en) 1991-02-28
HUT53625A (en) 1990-11-28
FI93106C (fi) 1995-02-27
NZ231793A (en) 1991-03-26
JPH02223569A (ja) 1990-09-05
DK633689D0 (da) 1989-12-14
SK708189A3 (en) 1997-01-08
FR2649701B2 (fr) 1991-11-22
PL161336B1 (pl) 1993-06-30
AU618432B2 (en) 1991-12-19
DK169967B1 (da) 1995-04-18
NO895030L (no) 1990-06-18
RU2037489C1 (ru) 1995-06-19
NO173060C (no) 1993-10-20
DE68905585D1 (de) 1993-04-29
CA2005590A1 (fr) 1990-06-15
HU896612D0 (en) 1990-02-28
GR3007788T3 (en:Method) 1993-08-31
YU47337B (sh) 1995-01-31
FR2649701A2 (fr) 1991-01-18
AU4618989A (en) 1990-06-21

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