PL110679B1 - Method of producing new n-substituted lactams - Google Patents

Method of producing new n-substituted lactams Download PDF

Info

Publication number
PL110679B1
PL110679B1 PL1977201601A PL20160177A PL110679B1 PL 110679 B1 PL110679 B1 PL 110679B1 PL 1977201601 A PL1977201601 A PL 1977201601A PL 20160177 A PL20160177 A PL 20160177A PL 110679 B1 PL110679 B1 PL 110679B1
Authority
PL
Poland
Prior art keywords
formula
keto
methyl
melting point
compound
Prior art date
Application number
PL1977201601A
Other languages
English (en)
Polish (pl)
Other versions
PL201601A1 (pl
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of PL201601A1 publication Critical patent/PL201601A1/xx
Publication of PL110679B1 publication Critical patent/PL110679B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2632-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/272-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08Oxygen atoms
    • C07D223/10Oxygen atoms attached in position 2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Cephalosporin Compounds (AREA)
PL1977201601A 1976-10-22 1977-10-19 Method of producing new n-substituted lactams PL110679B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB43934/76A GB1539817A (en) 1976-10-22 1976-10-22 N-substituted lactams

Publications (2)

Publication Number Publication Date
PL201601A1 PL201601A1 (pl) 1979-01-29
PL110679B1 true PL110679B1 (en) 1980-07-31

Family

ID=10431009

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1977201601A PL110679B1 (en) 1976-10-22 1977-10-19 Method of producing new n-substituted lactams

Country Status (27)

Country Link
US (1) US4162325A (en, 2012)
JP (1) JPS5839148B2 (en, 2012)
AT (1) AT352742B (en, 2012)
BE (1) BE859925A (en, 2012)
BG (1) BG28413A3 (en, 2012)
CA (1) CA1095040A (en, 2012)
CH (1) CH625214A5 (en, 2012)
CS (1) CS200231B2 (en, 2012)
CY (1) CY1037A (en, 2012)
DD (1) DD131930A5 (en, 2012)
DE (1) DE2747369A1 (en, 2012)
DK (1) DK461877A (en, 2012)
ES (1) ES463424A1 (en, 2012)
FI (1) FI66600C (en, 2012)
FR (1) FR2368474B1 (en, 2012)
GB (1) GB1539817A (en, 2012)
HK (1) HK2380A (en, 2012)
HU (1) HU174864B (en, 2012)
IL (1) IL53171A (en, 2012)
KE (1) KE3013A (en, 2012)
MY (1) MY8000264A (en, 2012)
NL (1) NL7711414A (en, 2012)
PL (1) PL110679B1 (en, 2012)
SE (1) SE425782B (en, 2012)
SU (2) SU805945A3 (en, 2012)
YU (1) YU251977A (en, 2012)
ZA (1) ZA776260B (en, 2012)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005689B1 (fr) * 1978-05-08 1981-03-18 U C B, S.A. Nouveaux acides lactame-N-acétiques et leurs amides, leurs procédés de préparation et compositions thérapeutiques
EP0115473A3 (de) * 1983-01-27 1987-01-21 Ciba-Geigy Ag Substituierte Pyrrolidinonderivate und Verfahren zu ihrer Herstellung
FI840260L (fi) * 1983-01-27 1984-07-28 Ciba Geigy Ag Pyrrolidinonderivat och foerfarande foer deras framstaellning.
IT1190378B (it) * 1985-06-21 1988-02-16 Isf Spa Derivati pirrolidonici
US5118811A (en) * 1989-04-13 1992-06-02 Japan Tobacco Inc. Amino acid derivatives possessing prolyl endopeptidase-inhibitory activities
US5206386A (en) * 1991-03-20 1993-04-27 Isp Investments Inc. Controlled release N-substituted pyrrolidone esters and process for the use thereof
DE4308034A1 (de) * 1993-03-13 1994-09-15 Cassella Ag Neue Heterocyclen, ihre Herstellung und ihre Verwendung
US5658940A (en) * 1995-10-06 1997-08-19 Celgene Corporation Succinimide and maleimide cytokine inhibitors
US5914332A (en) * 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
CN114685342B (zh) * 2020-12-25 2024-05-10 长沙博源医疗科技有限公司 一种左乙拉西坦衍生物、免疫原、抗左乙拉西坦特异性抗体及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3121723A (en) * 1955-11-02 1964-02-18 Sterling Drug Inc Lower alkyl n-(tertiary-amino-lower-alkyl) lower alkamates and quaternary ammonium salts thereof
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
NL7407140A (nl) * 1974-03-07 1975-09-09 Jose Maria Espinos Taya En Jos Werkwijze voor de bereiding van een n-gesub- stitueerd pyrrolidon.
AT360980B (de) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-alkylamiden des 2-oxo-1-pyrrolidins

Also Published As

Publication number Publication date
FI773069A7 (fi) 1978-04-23
SE425782B (sv) 1982-11-08
CA1095040A (en) 1981-02-03
DK461877A (da) 1978-04-23
FR2368474A1 (en, 2012) 1978-05-19
FR2368474B1 (fr) 1980-08-08
BE859925A (fr) 1978-04-20
DE2747369A1 (de) 1978-04-27
DD131930A5 (de) 1978-08-09
MY8000264A (en) 1980-12-31
NL7711414A (nl) 1978-04-25
US4162325A (en) 1979-07-24
PL201601A1 (pl) 1979-01-29
AT352742B (de) 1979-10-10
GB1539817A (en) 1979-02-07
SE7711667L (sv) 1978-04-23
HK2380A (en) 1980-01-25
KE3013A (en) 1980-02-01
FI66600B (fi) 1984-07-31
ES463424A1 (es) 1978-07-16
CY1037A (en) 1980-08-01
BG28413A3 (bg) 1980-04-15
CH625214A5 (en, 2012) 1981-09-15
CS200231B2 (en) 1980-08-29
ATA749677A (de) 1979-03-15
JPS5839148B2 (ja) 1983-08-27
IL53171A0 (en) 1977-12-30
IL53171A (en) 1982-02-28
SU805945A3 (ru) 1981-02-15
SU937450A1 (ru) 1982-06-23
JPS5353649A (en) 1978-05-16
YU251977A (en) 1983-01-21
FI66600C (fi) 1984-11-12
DE2747369C2 (en, 2012) 1987-11-12
ZA776260B (en) 1978-07-26
HU174864B (hu) 1980-03-28

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20061119