PH31454A - Pharmaceutical compositions containing a staurosporine. - Google Patents
Pharmaceutical compositions containing a staurosporine.Info
- Publication number
- PH31454A PH31454A PH49409A PH49409A PH31454A PH 31454 A PH31454 A PH 31454A PH 49409 A PH49409 A PH 49409A PH 49409 A PH49409 A PH 49409A PH 31454 A PH31454 A PH 31454A
- Authority
- PH
- Philippines
- Prior art keywords
- staurosporine
- pharmaceutical compositions
- compositions containing
- dispersion
- composition
- Prior art date
Links
- HKSZLNNOFSGOKW-UHFFFAOYSA-N ent-staurosporine Natural products C12=C3N4C5=CC=CC=C5C3=C3CNC(=O)C3=C2C2=CC=CC=C2N1C1CC(NC)C(OC)C4(C)O1 HKSZLNNOFSGOKW-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- HKSZLNNOFSGOKW-FYTWVXJKSA-N staurosporine Chemical compound C12=C3N4C5=CC=CC=C5C3=C3CNC(=O)C3=C2C2=CC=CC=C2N1[C@H]1C[C@@H](NC)[C@@H](OC)[C@]4(C)O1 HKSZLNNOFSGOKW-FYTWVXJKSA-N 0.000 title abstract 2
- CGPUWJWCVCFERF-UHFFFAOYSA-N staurosporine Natural products C12=C3N4C5=CC=CC=C5C3=C3CNC(=O)C3=C2C2=CC=CC=C2N1C1CC(NC)C(OC)C4(OC)O1 CGPUWJWCVCFERF-UHFFFAOYSA-N 0.000 title abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 239000006185 dispersion Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000005456 glyceride group Chemical group 0.000 abstract 1
- 229920001515 polyalkylene glycol Polymers 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 235000003441 saturated fatty acids Nutrition 0.000 abstract 1
- 150000004671 saturated fatty acids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939325395A GB9325395D0 (en) | 1993-12-11 | 1993-12-11 | Compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
PH31454A true PH31454A (en) | 1998-11-03 |
Family
ID=10746475
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH49409A PH31454A (en) | 1993-12-11 | 1994-11-18 | Pharmaceutical compositions containing a staurosporine. |
Country Status (17)
Country | Link |
---|---|
US (1) | US5736542A (pt) |
EP (1) | EP0657164B1 (pt) |
JP (1) | JPH07196512A (pt) |
KR (1) | KR100366176B1 (pt) |
AT (1) | ATE185970T1 (pt) |
AU (1) | AU692801B2 (pt) |
CA (1) | CA2137764C (pt) |
DE (1) | DE69421366T2 (pt) |
DK (1) | DK0657164T3 (pt) |
ES (1) | ES2140512T3 (pt) |
GB (1) | GB9325395D0 (pt) |
GR (1) | GR3032368T3 (pt) |
IL (1) | IL111872A (pt) |
NZ (1) | NZ270109A (pt) |
PH (1) | PH31454A (pt) |
PT (1) | PT657164E (pt) |
ZA (1) | ZA949824B (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7795246B2 (en) | 1998-08-06 | 2010-09-14 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
US6200968B1 (en) * | 1998-08-06 | 2001-03-13 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
US6242473B1 (en) * | 1999-01-08 | 2001-06-05 | Maxim Pharmaceuticals, Inc. | Treatment and prevention of reactive oxygen metabolite-mediated cellular damage |
GB9903547D0 (en) * | 1999-02-16 | 1999-04-07 | Novartis Ag | Organic compounds |
DE19917990A1 (de) * | 1999-04-20 | 2000-11-02 | Florian Lang | Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk |
CA2379035A1 (en) | 1999-07-13 | 2001-01-18 | Shiro Akinaga | Staurosporin derivatives |
DE10042137A1 (de) * | 2000-08-28 | 2002-03-14 | Florian Lang | sgk2 und sgk3 als diagnostische und therapeutische Targets |
PT1372611E (pt) * | 2001-03-26 | 2006-08-31 | Novartis Ag | Composicao farmaceutica compreendendo uma estaurosporina francamente soluvel em agua, um tensioactivo et um polimero soluvel em agua |
AU2003215623B2 (en) * | 2003-03-03 | 2009-10-22 | Florian Lang | Sgk1 as diagnostic and therapeutic target |
US20040246627A1 (en) * | 2003-06-06 | 2004-12-09 | Durrum Thomas M. | Disc drive pivot bearing assembly |
CA2533861A1 (en) | 2003-08-08 | 2005-02-17 | Novartis Ag | Combinations comprising staurosporines |
US7635675B2 (en) | 2003-08-13 | 2009-12-22 | Biocon Limited | Micro-particle fatty acid salt solid dosage formulations for therapeutic agents |
WO2006082448A1 (en) * | 2005-02-07 | 2006-08-10 | Topotarget Uk Limited | Assays for agents with selective cytotoxicty to hdac resistant cell lines |
US9994585B2 (en) | 2007-12-31 | 2018-06-12 | Aphios Corporation | Transplantation therapies |
US20100168219A1 (en) * | 2008-12-31 | 2010-07-01 | Jonathan Steven Alexander | Chronic inflammation and transplantation |
US9034347B2 (en) | 2011-12-19 | 2015-05-19 | Arphios Corporation | Drug delivery system and method for the treatment of neuro-degenerative disease |
EP2925314B1 (en) | 2012-11-28 | 2020-04-01 | Aphios Corporation | Combination therapeutics and methods for the treatment of neurodegenerative and other diseases |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60185719A (ja) * | 1984-03-06 | 1985-09-21 | Ajinomoto Co Inc | 抗腫瘍剤 |
JPH0699311B2 (ja) * | 1986-11-06 | 1994-12-07 | 旭化成工業株式会社 | 抗血管レン縮剤および血管弛緩剤 |
US5093330A (en) * | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
IL86632A0 (en) * | 1987-06-15 | 1988-11-30 | Ciba Geigy Ag | Derivatives substituted at methyl-amino nitrogen |
JPH01143877A (ja) * | 1987-11-30 | 1989-06-06 | Asahi Chem Ind Co Ltd | スタウロスポリン誘導体 |
EP0383919A4 (en) * | 1988-02-04 | 1992-08-05 | Kyowa Hakko Kogyo Co., Ltd. | Staurosporin derivatives |
JPH0725786A (ja) * | 1990-05-16 | 1995-01-27 | Univ Rockefeller | アルツハイマー病を伴うアミロイドーシスの治療 |
JPH06501024A (ja) * | 1991-03-29 | 1994-01-27 | アメリカ合衆国 | 皮膚腫瘍形成を予防し、存在する腫瘍の後退の原因になるための医薬組成物と方法 |
JPH0597708A (ja) * | 1991-10-02 | 1993-04-20 | Lion Corp | 歯周病治療剤 |
AU2866992A (en) * | 1991-10-10 | 1993-05-03 | Schering Corporation | 4'-(n-substituted-n-oxide)staurosporine derivatives |
JPH05247055A (ja) * | 1992-03-03 | 1993-09-24 | Meiji Seika Kaisha Ltd | スタウロスポリン誘導体及びそれを含有する抗腫瘍効果増強剤 |
-
1993
- 1993-12-11 GB GB939325395A patent/GB9325395D0/en active Pending
-
1994
- 1994-11-18 PH PH49409A patent/PH31454A/en unknown
- 1994-11-22 US US08/343,404 patent/US5736542A/en not_active Expired - Fee Related
- 1994-12-02 PT PT94308954T patent/PT657164E/pt unknown
- 1994-12-02 EP EP94308954A patent/EP0657164B1/en not_active Expired - Lifetime
- 1994-12-02 AT AT94308954T patent/ATE185970T1/de active
- 1994-12-02 DE DE69421366T patent/DE69421366T2/de not_active Expired - Lifetime
- 1994-12-02 DK DK94308954T patent/DK0657164T3/da active
- 1994-12-02 ES ES94308954T patent/ES2140512T3/es not_active Expired - Lifetime
- 1994-12-05 IL IL111872A patent/IL111872A/en not_active IP Right Cessation
- 1994-12-08 AU AU80308/94A patent/AU692801B2/en not_active Ceased
- 1994-12-09 ZA ZA949824A patent/ZA949824B/xx unknown
- 1994-12-09 KR KR1019940033397A patent/KR100366176B1/ko not_active IP Right Cessation
- 1994-12-09 NZ NZ270109A patent/NZ270109A/en not_active IP Right Cessation
- 1994-12-09 CA CA002137764A patent/CA2137764C/en not_active Expired - Fee Related
- 1994-12-12 JP JP6307534A patent/JPH07196512A/ja active Pending
-
2000
- 2000-01-14 GR GR20000400066T patent/GR3032368T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0657164A1 (en) | 1995-06-14 |
PT657164E (pt) | 2000-04-28 |
US5736542A (en) | 1998-04-07 |
KR100366176B1 (ko) | 2003-03-03 |
DE69421366T2 (de) | 2000-03-23 |
JPH07196512A (ja) | 1995-08-01 |
KR960021018A (ko) | 1996-07-18 |
GB9325395D0 (en) | 1994-02-16 |
IL111872A0 (en) | 1995-06-29 |
NZ270109A (en) | 1996-11-26 |
IL111872A (en) | 1998-02-08 |
EP0657164B1 (en) | 1999-10-27 |
GR3032368T3 (en) | 2000-04-27 |
CA2137764C (en) | 2006-02-07 |
DE69421366D1 (de) | 1999-12-02 |
DK0657164T3 (da) | 2000-04-17 |
ES2140512T3 (es) | 2000-03-01 |
CA2137764A1 (en) | 1995-06-12 |
AU8030894A (en) | 1995-06-22 |
AU692801B2 (en) | 1998-06-18 |
ZA949824B (en) | 1995-07-13 |
ATE185970T1 (de) | 1999-11-15 |
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