PH30172A - Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives - Google Patents
Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivativesInfo
- Publication number
- PH30172A PH30172A PH47762A PH47762A PH30172A PH 30172 A PH30172 A PH 30172A PH 47762 A PH47762 A PH 47762A PH 47762 A PH47762 A PH 47762A PH 30172 A PH30172 A PH 30172A
- Authority
- PH
- Philippines
- Prior art keywords
- cyclohexane
- carboxylic acid
- substituted phenyl
- acid derivatives
- heterocyclically substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4304455A DE4304455A1 (de) | 1993-02-15 | 1993-02-15 | Heterocyclisch substituierte Phenyl-cyclohexan-carbonsäurederivate |
Publications (1)
Publication Number | Publication Date |
---|---|
PH30172A true PH30172A (en) | 1997-01-21 |
Family
ID=6480447
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH47762A PH30172A (en) | 1993-02-15 | 1994-02-14 | Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives |
Country Status (25)
Country | Link |
---|---|
US (1) | US5395840A (fr) |
EP (1) | EP0611767B1 (fr) |
JP (1) | JPH06293741A (fr) |
KR (1) | KR940019708A (fr) |
CN (1) | CN1057085C (fr) |
AT (1) | ATE196141T1 (fr) |
AU (1) | AU672262B2 (fr) |
CA (1) | CA2115536C (fr) |
CZ (1) | CZ289096B6 (fr) |
DE (2) | DE4304455A1 (fr) |
DK (1) | DK0611767T3 (fr) |
ES (1) | ES2151908T3 (fr) |
FI (1) | FI106716B (fr) |
GR (1) | GR3034957T3 (fr) |
IL (1) | IL108625A (fr) |
MY (1) | MY131595A (fr) |
NO (1) | NO300810B1 (fr) |
NZ (1) | NZ250864A (fr) |
PH (1) | PH30172A (fr) |
PL (1) | PL177834B1 (fr) |
PT (1) | PT611767E (fr) |
RU (1) | RU2119480C1 (fr) |
SK (1) | SK15294A3 (fr) |
UA (1) | UA35574C2 (fr) |
ZA (1) | ZA94984B (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW300219B (fr) * | 1991-09-14 | 1997-03-11 | Hoechst Ag | |
DE19503160A1 (de) * | 1995-02-01 | 1996-08-08 | Bayer Ag | Verwendung von Phenylcyclohexylcarbonsäureamiden |
HRP960015B1 (en) * | 1995-02-01 | 2000-12-31 | Bayer Ag | Substituted indole derivatives |
DE19525028A1 (de) * | 1995-07-10 | 1997-01-16 | Bayer Ag | Amide und Sulfonamide von heterocyclisch substituierten Benzylaminen |
HUP0100179A3 (en) | 1997-07-03 | 2002-12-28 | Bristol Myers Squibb Pharma Co | Imidazopyrimidine and imidazopyridine derivatives and pharmaceutical compositions thereof |
US6124463A (en) * | 1998-07-02 | 2000-09-26 | Dupont Pharmaceuticals | Benzimidazoles as corticotropin release factor antagonists |
US6365589B1 (en) | 1998-07-02 | 2002-04-02 | Bristol-Myers Squibb Pharma Company | Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists |
DK1131301T3 (da) * | 1998-11-17 | 2006-01-09 | Abbott Gmbh & Co Kg | 2-phenylbenzimidazoler og 2-phenylindoler, fremstilling af anvendelse heraf |
DE19924818A1 (de) | 1999-05-29 | 2000-11-30 | Bayer Ag | Substituierte Phenylcyclohexancarbonsäureamide |
DE19924819A1 (de) * | 1999-05-29 | 2000-11-30 | Bayer Ag | Substituierte Phenylcyclohexancarbonsäurebenzylamid (Adenosinaufnahmeinhibitoren) |
DE10044792A1 (de) * | 2000-09-11 | 2002-04-04 | Bayer Ag | Substituierte Phenylcyclohexancarbonsäureamide und ihre Verwendung |
ES2399233T3 (es) | 2006-05-09 | 2013-03-26 | Mitsubishi Gas Chemical Company, Inc. | Preparación de 4-(4-ALQUILCICLOHEXIL)BENZALDEHÍDO |
PE20160127A1 (es) | 2009-06-17 | 2016-02-24 | Vertex Pharma | COMPUESTO ACIDO (2S,3S)-3-((2-(5-FLUORO-1H-PIRROLO[2,3-B]PIRIDIN-3-IL)-5-FLUOROPIRIMIDIN-4-IL)AMINO)BICICLO[2.2.2]OCTANO-2-CARBOXILICO COMO INHIBIDOR DE LA REPLICACION DEL VIRUS DE LA GRIPE A H1N1, H2N2, H3N2 o H5N1 |
WO2012083117A1 (fr) | 2010-12-16 | 2012-06-21 | Vertex Pharmaceuticals Incorporated | Inhibiteurs de la réplication des virus de la grippe |
AP2013007331A0 (en) | 2011-06-24 | 2013-12-31 | Amgen Inc | TRPM8 antagonists and their use in treatments |
WO2012177896A1 (fr) | 2011-06-24 | 2012-12-27 | Amgen Inc. | Antagonistes de trpm8 et leur utilisation dans le cadre thérapeutique |
UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
EA025186B1 (ru) | 2012-06-29 | 2016-11-30 | Пфайзер Инк. | НОВЫЕ 4-(ЗАМЕЩЕННЫЙ АМИНО)-7Н-ПИРРОЛО[2,3-d]ПИРИМИДИНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ LRRK2 |
US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
ME03460B (fr) | 2013-11-13 | 2020-01-20 | Vertex Pharma | Inhibiteurs de la réplication des virus de la grippe |
RU2019104421A (ru) | 2013-11-13 | 2019-04-17 | Вертекс Фармасьютикалз Инкорпорейтед | Способы получения ингибиторов репликации вирусов гриппа |
WO2015092592A1 (fr) | 2013-12-17 | 2015-06-25 | Pfizer Inc. | Nouvelles 1h-pyrrolo[2,3- b]pyridines 3,4-disubstituées et 7h-pyrrolo[2,3-c]pyridazines 4,5-disubstituées en tant qu'inhibiteurs de la lrrk2 |
WO2016183120A1 (fr) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Inhibiteurs de la réplication des virus de la grippe |
WO2016183116A1 (fr) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Procédés de préparation d'inhibiteurs de réplication des virus de la grippe |
MX2018003215A (es) | 2015-09-14 | 2018-06-08 | Pfizer | Derivados de imidazo[4,5-c]quinolina e imidazo[4,5-c][1,5]naftirid ina novedosos como inhibidores de lrrk2. |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5138069A (en) * | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
IE64514B1 (en) * | 1989-05-23 | 1995-08-09 | Zeneca Ltd | Azaindenes |
GB8911854D0 (en) * | 1989-05-23 | 1989-07-12 | Ici Plc | Heterocyclic compounds |
US5164407A (en) * | 1989-07-03 | 1992-11-17 | Merck & Co., Inc. | Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists |
DE69130192T2 (de) * | 1990-06-08 | 1999-03-25 | Hoechst Marion Roussel, Puteaux | Benzimidazol-Derivate, Verfahren und Zwischenprodukte zu ihrer Herstellung, ihre Anwendung als Arzneimittel und diese enthaltende pharmazeutische Zusammensetzungen |
RU1836357C (ru) * | 1990-07-23 | 1993-08-23 | Др.Карл Томэ ГмбХ | Производные бензимидазола, их изомеры, смеси изомеров, гидраты или их физиологически переносимые соли, обладающие антагонистическими в отношении ангиотензина свойствами |
EP0470543A1 (fr) * | 1990-08-10 | 1992-02-12 | Dr. Karl Thomae GmbH | Imidazoles hétérocycliques, médicaments contenant ces composés et procédés pour leur préparation |
DE4031635A1 (de) * | 1990-10-05 | 1992-04-09 | Thomae Gmbh Dr K | Substituierte 1-benzyl-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
DE4224133A1 (de) * | 1992-07-22 | 1994-01-27 | Thomae Gmbh Dr K | Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
DE4200954A1 (de) * | 1991-04-26 | 1992-10-29 | Bayer Ag | Heterocyclisch substituierte phenylessigsaeurederivate |
-
1993
- 1993-02-15 DE DE4304455A patent/DE4304455A1/de not_active Withdrawn
-
1994
- 1994-01-31 AU AU54807/94A patent/AU672262B2/en not_active Ceased
- 1994-02-02 ES ES94101543T patent/ES2151908T3/es not_active Expired - Lifetime
- 1994-02-02 DK DK94101543T patent/DK0611767T3/da active
- 1994-02-02 PT PT94101543T patent/PT611767E/pt unknown
- 1994-02-02 DE DE59409509T patent/DE59409509D1/de not_active Expired - Fee Related
- 1994-02-02 AT AT94101543T patent/ATE196141T1/de not_active IP Right Cessation
- 1994-02-02 EP EP94101543A patent/EP0611767B1/fr not_active Expired - Lifetime
- 1994-02-08 US US08/193,835 patent/US5395840A/en not_active Expired - Fee Related
- 1994-02-09 SK SK152-94A patent/SK15294A3/sk unknown
- 1994-02-11 IL IL108625A patent/IL108625A/xx not_active IP Right Cessation
- 1994-02-11 FI FI940659A patent/FI106716B/fi active
- 1994-02-11 NZ NZ250864A patent/NZ250864A/en unknown
- 1994-02-11 PL PL94302213A patent/PL177834B1/pl unknown
- 1994-02-11 UA UA94005092A patent/UA35574C2/uk unknown
- 1994-02-11 CA CA002115536A patent/CA2115536C/fr not_active Expired - Fee Related
- 1994-02-14 PH PH47762A patent/PH30172A/en unknown
- 1994-02-14 RU RU94004975A patent/RU2119480C1/ru active
- 1994-02-14 MY MYPI94000321A patent/MY131595A/en unknown
- 1994-02-14 KR KR1019940002533A patent/KR940019708A/ko active IP Right Grant
- 1994-02-14 ZA ZA94984A patent/ZA94984B/xx unknown
- 1994-02-14 JP JP6037543A patent/JPH06293741A/ja active Pending
- 1994-02-14 NO NO940506A patent/NO300810B1/no not_active IP Right Cessation
- 1994-02-15 CZ CZ1994329A patent/CZ289096B6/cs not_active IP Right Cessation
- 1994-02-15 CN CN94101553A patent/CN1057085C/zh not_active Expired - Fee Related
-
2000
- 2000-11-30 GR GR20000402660T patent/GR3034957T3/el not_active IP Right Cessation
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