PH30172A - Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives - Google Patents
Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivativesInfo
- Publication number
- PH30172A PH30172A PH47762A PH47762A PH30172A PH 30172 A PH30172 A PH 30172A PH 47762 A PH47762 A PH 47762A PH 47762 A PH47762 A PH 47762A PH 30172 A PH30172 A PH 30172A
- Authority
- PH
- Philippines
- Prior art keywords
- cyclohexane
- carboxylic acid
- substituted phenyl
- acid derivatives
- heterocyclically substituted
- Prior art date
Links
- QXXHHHWXFHPNOS-UHFFFAOYSA-N 1-phenylcyclohexane-1-carboxylic acid Chemical class C=1C=CC=CC=1C1(C(=O)O)CCCCC1 QXXHHHWXFHPNOS-UHFFFAOYSA-N 0.000 title 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4304455A DE4304455A1 (de) | 1993-02-15 | 1993-02-15 | Heterocyclisch substituierte Phenyl-cyclohexan-carbonsäurederivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH30172A true PH30172A (en) | 1997-01-21 |
Family
ID=6480447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH47762A PH30172A (en) | 1993-02-15 | 1994-02-14 | Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5395840A (enExample) |
| EP (1) | EP0611767B1 (enExample) |
| JP (1) | JPH06293741A (enExample) |
| KR (1) | KR940019708A (enExample) |
| CN (1) | CN1057085C (enExample) |
| AT (1) | ATE196141T1 (enExample) |
| AU (1) | AU672262B2 (enExample) |
| CA (1) | CA2115536C (enExample) |
| CZ (1) | CZ289096B6 (enExample) |
| DE (2) | DE4304455A1 (enExample) |
| DK (1) | DK0611767T3 (enExample) |
| ES (1) | ES2151908T3 (enExample) |
| FI (1) | FI106716B (enExample) |
| GR (1) | GR3034957T3 (enExample) |
| IL (1) | IL108625A (enExample) |
| MY (1) | MY131595A (enExample) |
| NO (1) | NO300810B1 (enExample) |
| NZ (1) | NZ250864A (enExample) |
| PH (1) | PH30172A (enExample) |
| PL (1) | PL177834B1 (enExample) |
| PT (1) | PT611767E (enExample) |
| RU (1) | RU2119480C1 (enExample) |
| SK (1) | SK15294A3 (enExample) |
| UA (1) | UA35574C2 (enExample) |
| ZA (1) | ZA94984B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW300219B (enExample) * | 1991-09-14 | 1997-03-11 | Hoechst Ag | |
| DE19503160A1 (de) * | 1995-02-01 | 1996-08-08 | Bayer Ag | Verwendung von Phenylcyclohexylcarbonsäureamiden |
| HRP960015B1 (en) * | 1995-02-01 | 2000-12-31 | Bayer Ag | Substituted indole derivatives |
| DE19525028A1 (de) * | 1995-07-10 | 1997-01-16 | Bayer Ag | Amide und Sulfonamide von heterocyclisch substituierten Benzylaminen |
| JP2002507996A (ja) | 1997-07-03 | 2002-03-12 | デュポン ファーマシューティカルズ カンパニー | 神経学的障害を治療するためのイミダゾピリミジン類およびイミダゾピリジン類 |
| US6124463A (en) * | 1998-07-02 | 2000-09-26 | Dupont Pharmaceuticals | Benzimidazoles as corticotropin release factor antagonists |
| US6365589B1 (en) | 1998-07-02 | 2002-04-02 | Bristol-Myers Squibb Pharma Company | Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists |
| JP2002529537A (ja) * | 1998-11-17 | 2002-09-10 | ビーエーエスエフ アクチェンゲゼルシャフト | ２−フェニルベンズイミダゾールおよび２−フェニルインドール、その製造方法ならびに使用 |
| DE19924818A1 (de) | 1999-05-29 | 2000-11-30 | Bayer Ag | Substituierte Phenylcyclohexancarbonsäureamide |
| DE19924819A1 (de) * | 1999-05-29 | 2000-11-30 | Bayer Ag | Substituierte Phenylcyclohexancarbonsäurebenzylamid (Adenosinaufnahmeinhibitoren) |
| DE10044792A1 (de) | 2000-09-11 | 2002-04-04 | Bayer Ag | Substituierte Phenylcyclohexancarbonsäureamide und ihre Verwendung |
| WO2007129707A1 (ja) | 2006-05-09 | 2007-11-15 | Mitsubishi Gas Chemical Company, Inc. | ４－（４－アルキルシクロヘキシル）ベンズアルデヒド |
| GEP20207129B (en) | 2009-06-17 | 2020-07-10 | Vertex Pharma | Inhibitors of influenza viruses replication |
| RU2013132681A (ru) | 2010-12-16 | 2015-01-27 | Вертекс Фармасьютикалз Инкорпорейтед | Ингибиторы репликации вирусов гриппа |
| EP2723718A1 (en) | 2011-06-24 | 2014-04-30 | Amgen Inc. | Trpm8 antagonists and their use in treatments |
| AP2013007331A0 (en) | 2011-06-24 | 2013-12-31 | Amgen Inc | TRPM8 antagonists and their use in treatments |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| EA025186B1 (ru) | 2012-06-29 | 2016-11-30 | Пфайзер Инк. | НОВЫЕ 4-(ЗАМЕЩЕННЫЙ АМИНО)-7Н-ПИРРОЛО[2,3-d]ПИРИМИДИНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ LRRK2 |
| US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
| HUE038820T2 (hu) | 2013-11-13 | 2018-11-28 | Vertex Pharma | Eljárás influenzavírusok replikációjának inhibitorai elõállítására |
| PT3068776T (pt) | 2013-11-13 | 2019-08-26 | Vertex Pharma | Inibidores da replicação de vírus da gripe |
| EP3083618B1 (en) | 2013-12-17 | 2018-02-21 | Pfizer Inc | Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors |
| WO2016183120A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| EP3294717B1 (en) | 2015-05-13 | 2020-07-29 | Vertex Pharmaceuticals Inc. | Methods of preparing inhibitors of influenza viruses replication |
| RU2722149C1 (ru) | 2015-09-14 | 2020-05-27 | Пфайзер Инк. | Новые производные имидазо[4,5-c] хинолинов и имидазо[4,5-c][1,5] нафтиридинов в качестве ингибиторов LRRK2 |
| WO2023171679A1 (ja) * | 2022-03-08 | 2023-09-14 | Ｋｊケミカルズ株式会社 | 高安全性アミド化合物を含有する組成物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5138069A (en) * | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
| IE64514B1 (en) * | 1989-05-23 | 1995-08-09 | Zeneca Ltd | Azaindenes |
| GB8911854D0 (en) * | 1989-05-23 | 1989-07-12 | Ici Plc | Heterocyclic compounds |
| US5164407A (en) * | 1989-07-03 | 1992-11-17 | Merck & Co., Inc. | Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists |
| DE69130192T2 (de) * | 1990-06-08 | 1999-03-25 | Hoechst Marion Roussel, Puteaux | Benzimidazol-Derivate, Verfahren und Zwischenprodukte zu ihrer Herstellung, ihre Anwendung als Arzneimittel und diese enthaltende pharmazeutische Zusammensetzungen |
| RU1836357C (ru) * | 1990-07-23 | 1993-08-23 | Др.Карл Томэ ГмбХ | Производные бензимидазола, их изомеры, смеси изомеров, гидраты или их физиологически переносимые соли, обладающие антагонистическими в отношении ангиотензина свойствами |
| EP0470543A1 (de) * | 1990-08-10 | 1992-02-12 | Dr. Karl Thomae GmbH | Heterocyclische Imidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zur ihrer Herstellung |
| DE4031635A1 (de) * | 1990-10-05 | 1992-04-09 | Thomae Gmbh Dr K | Substituierte 1-benzyl-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE4224133A1 (de) * | 1992-07-22 | 1994-01-27 | Thomae Gmbh Dr K | Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| DE4200954A1 (de) * | 1991-04-26 | 1992-10-29 | Bayer Ag | Heterocyclisch substituierte phenylessigsaeurederivate |
-
1993
- 1993-02-15 DE DE4304455A patent/DE4304455A1/de not_active Withdrawn
-
1994
- 1994-01-31 AU AU54807/94A patent/AU672262B2/en not_active Ceased
- 1994-02-02 EP EP94101543A patent/EP0611767B1/de not_active Expired - Lifetime
- 1994-02-02 DK DK94101543T patent/DK0611767T3/da active
- 1994-02-02 ES ES94101543T patent/ES2151908T3/es not_active Expired - Lifetime
- 1994-02-02 AT AT94101543T patent/ATE196141T1/de not_active IP Right Cessation
- 1994-02-02 PT PT94101543T patent/PT611767E/pt unknown
- 1994-02-02 DE DE59409509T patent/DE59409509D1/de not_active Expired - Fee Related
- 1994-02-08 US US08/193,835 patent/US5395840A/en not_active Expired - Fee Related
- 1994-02-09 SK SK152-94A patent/SK15294A3/sk unknown
- 1994-02-11 PL PL94302213A patent/PL177834B1/pl unknown
- 1994-02-11 CA CA002115536A patent/CA2115536C/en not_active Expired - Fee Related
- 1994-02-11 IL IL108625A patent/IL108625A/xx not_active IP Right Cessation
- 1994-02-11 FI FI940659A patent/FI106716B/fi active
- 1994-02-11 UA UA94005092A patent/UA35574C2/uk unknown
- 1994-02-11 NZ NZ250864A patent/NZ250864A/en unknown
- 1994-02-14 ZA ZA94984A patent/ZA94984B/xx unknown
- 1994-02-14 NO NO940506A patent/NO300810B1/no not_active IP Right Cessation
- 1994-02-14 JP JP6037543A patent/JPH06293741A/ja active Pending
- 1994-02-14 MY MYPI94000321A patent/MY131595A/en unknown
- 1994-02-14 RU RU94004975A patent/RU2119480C1/ru active
- 1994-02-14 KR KR1019940002533A patent/KR940019708A/ko not_active Abandoned
- 1994-02-14 PH PH47762A patent/PH30172A/en unknown
- 1994-02-15 CN CN94101553A patent/CN1057085C/zh not_active Expired - Fee Related
- 1994-02-15 CZ CZ1994329A patent/CZ289096B6/cs not_active IP Right Cessation
-
2000
- 2000-11-30 GR GR20000402660T patent/GR3034957T3/el not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU672262B2 (en) | Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives | |
| EP0501975A4 (en) | Antihypertensive compositions and use thereof | |
| NO2004009I1 (no) | Melagatran, stereoisomerer derav eller fysiologisksalter eller estrer derav | |
| CA2131316A1 (en) | A thrombin blood fraction for use in a medical procedure | |
| HUT48116A (en) | Medicaments comprising phenyl mercapto derivatives | |
| AU3544693A (en) | Pharmaceuticals comprising polyhydroxymethylene derivatives, process for their preparation and use | |
| DK0380331T3 (da) | Anvendelse af di-tert.butylhydroxyphenylthioderivater til fremstilling af et lægemiddel til behandling eller forebyggelse af arteriosklerose eller atherosklerose | |
| PL298890A1 (en) | Sulfonylobenzyl substituted benzo- and pyridopyridones, method of obtaining sames and therapeutic agents containing them | |
| HU911756D0 (en) | Process for the production of medical preparations containing magnesium-pyridoxal-5'-phosphate-glutaminate, for the preventing of arterial diseases | |
| AU617044B2 (en) | Herbicidal 1,3,5-triazin-2-ylaminocarbonylamino- sulfonylbenzoic esters, the preparation and use thereof | |
| AU7664991A (en) | Medicament for treating hyperlipidaemia and/or atherosclerosis | |
| AU2443888A (en) | Agents for treating high blood pressure and cardiac insufficiency | |
| GR3019270T3 (en) | Gamma-linolenic acid for the preparation of a medicament for preventing reocclusion of arteries | |
| HUT46214A (en) | Process for producing medical preparation suitable for treatment of peptic ulcer | |
| AU4610689A (en) | Pyridine-3-peroxycarboxylic acid monopersulfate | |
| ES2117114T3 (es) | Nuevos derivados de tiaxolidin-diona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
| HUT46909A (en) | Process for production of substituated quinoxanileimidasoline-2,4-dions and medical preparatives containing such compositions | |
| HK8994A (en) | Medicament for treatment of pregnancy-induced hypertension | |
| CA2367024A1 (en) | A thrombin blood fraction for use in a medical procedure |