PH23448A - Quinoline compounds - Google Patents

Quinoline compounds

Info

Publication number
PH23448A
PH23448A PH36289A PH36289DA PH23448A PH 23448 A PH23448 A PH 23448A PH 36289 A PH36289 A PH 36289A PH 36289D A PH36289D A PH 36289DA PH 23448 A PH23448 A PH 23448A
Authority
PH
Philippines
Prior art keywords
quinoline compounds
quinoline
compounds
concerned
chem
Prior art date
Application number
PH36289A
Other languages
English (en)
Inventor
Arthur Phillips
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of PH23448A publication Critical patent/PH23448A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Secondary Cells (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PH36289A 1986-12-23 1987-12-22 Quinoline compounds PH23448A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868630702A GB8630702D0 (en) 1986-12-23 1986-12-23 Quinoline compound

Publications (1)

Publication Number Publication Date
PH23448A true PH23448A (en) 1989-08-07

Family

ID=10609475

Family Applications (1)

Application Number Title Priority Date Filing Date
PH36289A PH23448A (en) 1986-12-23 1987-12-22 Quinoline compounds

Country Status (22)

Country Link
US (1) US4937248A (xx)
EP (1) EP0272910B1 (xx)
JP (1) JPS63166866A (xx)
KR (1) KR880007514A (xx)
AT (1) ATE65993T1 (xx)
AU (1) AU594220B2 (xx)
CA (1) CA1318671C (xx)
DE (1) DE3772015D1 (xx)
DK (1) DK163429C (xx)
ES (1) ES2029842T3 (xx)
FI (1) FI90768C (xx)
GB (1) GB8630702D0 (xx)
GR (1) GR3002445T3 (xx)
HU (1) HU196991B (xx)
IE (1) IE60619B1 (xx)
IL (1) IL84917A (xx)
MX (1) MX9203788A (xx)
MY (1) MY102277A (xx)
NZ (1) NZ223036A (xx)
PH (1) PH23448A (xx)
PT (1) PT86448B (xx)
ZA (1) ZA879615B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166160A (en) * 1986-12-23 1992-11-24 Burroughs Wellcome Co. Quinoline compound
GB8820174D0 (en) * 1988-08-25 1988-09-28 Wellcome Found Quinoline compound
SK3902000A3 (en) * 1997-09-24 2000-12-11 Orion Corp Bisethers of 1-oxa, aza and thianaphthalen-2-ones as phospholamban inhibitors
TR200200507T2 (tr) 1999-08-27 2002-10-21 Ligand Pharmaceuticals Inc Androjen reseptörü modülatör bileşikleri ve metotları
US6566372B1 (en) 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
WO2001016133A2 (en) 1999-08-27 2001-03-08 Ligand Pharmaceuticals Incorporated 8-substituted-6-trifluoromethyl-9-pyrido[3,2-g]quinoline compounds as androgen receptor modulators
WO2001019770A2 (en) 1999-09-14 2001-03-22 Ligand Pharmaceuticals Incorporated Rxr modulators with improved pharmacologic profile
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US7816372B2 (en) 2003-08-22 2010-10-19 Ligand Pharmaceuticals Incorporated 6-cycloamino-2-quinolinone derivatives as androgen receptor modulator compounds
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EA020466B1 (ru) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
EP2810951B1 (en) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EA201391254A1 (ru) 2011-03-01 2014-02-28 Синерджи Фармасьютикалз Инк. Способ получения агонистов гуанилатциклазы c
EP2958577A2 (en) 2013-02-25 2015-12-30 Synergy Pharmaceuticals Inc. Guanylate cyclase receptor agonists for use in colonic cleansing
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
PT3004138T (pt) 2013-06-05 2024-06-18 Bausch Health Ireland Ltd Agonistas ultrapuros de guanilato ciclase c, método de produção e utilização dos mesmos
AU2014305843B2 (en) 2013-08-09 2019-08-29 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
WO2020237096A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2616855A (en) * 1948-01-15 1952-11-04 Procter & Gamble Detergent composition
US4329347A (en) * 1978-02-17 1982-05-11 Boehringer Ingelheim Gmbh Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
PT79699B (en) * 1983-12-22 1986-12-10 Pfizer Process for preparing quinolone inotropic agents
ES8608874A1 (es) * 1984-05-29 1986-09-01 Pfizer Un procedimiento para la preparacion de una 2-(1h)-quinolona
US4760064A (en) * 1984-12-18 1988-07-26 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds, compositions containing same and processes for preparing same
US4845100A (en) * 1985-04-12 1989-07-04 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same
FR2580646A1 (fr) * 1985-04-19 1986-10-24 Synthelabo Derives de 2(1h)-quinolinone, leur preparation et leur application en therapeutique
GB8529362D0 (en) * 1985-11-28 1986-01-02 Pfizer Ltd Quinolone cardiac stimulants
DK111387A (da) * 1986-03-05 1987-09-06 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne
DE3784401T2 (de) * 1986-07-31 1993-08-12 Otsuka Pharma Co Ltd Karbostyril-derivate und ihre salze, verfahren zu ihrer herstellung und diese enthaltende kardiotonische zusammensetzung.

Also Published As

Publication number Publication date
NZ223036A (en) 1990-11-27
HUT45984A (en) 1988-09-28
DE3772015D1 (de) 1991-09-12
ATE65993T1 (de) 1991-08-15
PT86448B (pt) 1990-11-20
FI875666A (fi) 1988-06-24
US4937248A (en) 1990-06-26
GB8630702D0 (en) 1987-02-04
CA1318671C (en) 1993-06-01
IE873490L (en) 1988-06-23
GR3002445T3 (en) 1992-12-30
PT86448A (en) 1988-01-01
DK680887D0 (da) 1987-12-22
IL84917A0 (en) 1988-06-30
ZA879615B (en) 1989-08-30
MX9203788A (es) 1992-07-01
JPS63166866A (ja) 1988-07-11
DK163429B (da) 1992-03-02
FI875666A0 (fi) 1987-12-22
EP0272910A1 (en) 1988-06-29
HU196991B (en) 1989-02-28
FI90768C (fi) 1994-03-25
DK163429C (da) 1992-07-20
AU594220B2 (en) 1990-03-01
MY102277A (en) 1992-05-15
DK680887A (da) 1988-06-24
EP0272910B1 (en) 1991-08-07
IL84917A (en) 1991-08-16
IE60619B1 (en) 1994-07-27
KR880007514A (ko) 1988-08-27
ES2029842T3 (es) 1992-10-01
FI90768B (fi) 1993-12-15
AU8293387A (en) 1988-06-23

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