ATE65993T1 - Chinolinverbindung. - Google Patents
Chinolinverbindung.Info
- Publication number
- ATE65993T1 ATE65993T1 AT87311275T AT87311275T ATE65993T1 AT E65993 T1 ATE65993 T1 AT E65993T1 AT 87311275 T AT87311275 T AT 87311275T AT 87311275 T AT87311275 T AT 87311275T AT E65993 T1 ATE65993 T1 AT E65993T1
- Authority
- AT
- Austria
- Prior art keywords
- quinoline compound
- compound
- quinoline
- concerned
- chem
- Prior art date
Links
- -1 QUINOLINE COMPOUND Chemical class 0.000 title 1
- SMWDFEZZVXVKRB-UHFFFAOYSA-N anhydrous quinoline Natural products N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Secondary Cells (AREA)
- Carbon And Carbon Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868630702A GB8630702D0 (en) | 1986-12-23 | 1986-12-23 | Quinoline compound |
| EP87311275A EP0272910B1 (de) | 1986-12-23 | 1987-12-22 | Chinolinverbindung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE65993T1 true ATE65993T1 (de) | 1991-08-15 |
Family
ID=10609475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87311275T ATE65993T1 (de) | 1986-12-23 | 1987-12-22 | Chinolinverbindung. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4937248A (de) |
| EP (1) | EP0272910B1 (de) |
| JP (1) | JPS63166866A (de) |
| KR (1) | KR880007514A (de) |
| AT (1) | ATE65993T1 (de) |
| AU (1) | AU594220B2 (de) |
| CA (1) | CA1318671C (de) |
| DE (1) | DE3772015D1 (de) |
| DK (1) | DK163429C (de) |
| ES (1) | ES2029842T3 (de) |
| FI (1) | FI90768C (de) |
| GB (1) | GB8630702D0 (de) |
| GR (1) | GR3002445T3 (de) |
| HU (1) | HU196991B (de) |
| IE (1) | IE60619B1 (de) |
| IL (1) | IL84917A (de) |
| MX (1) | MX9203788A (de) |
| MY (1) | MY102277A (de) |
| NZ (1) | NZ223036A (de) |
| PH (1) | PH23448A (de) |
| PT (1) | PT86448B (de) |
| ZA (1) | ZA879615B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5166160A (en) * | 1986-12-23 | 1992-11-24 | Burroughs Wellcome Co. | Quinoline compound |
| GB8820174D0 (en) * | 1988-08-25 | 1988-09-28 | Wellcome Found | Quinoline compound |
| EP1017691A1 (de) * | 1997-09-24 | 2000-07-12 | Orion Corporation (Orion-Yhtyma Oy) | Diether von 1-oxa-, aza- und thianaphthalin-2-onen als phospholambanhemmer |
| CN1391576A (zh) | 1999-08-27 | 2003-01-15 | 利甘德药品公司 | 雄激素受体调节剂化合物及方法 |
| US6566372B1 (en) | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
| JP2003508397A (ja) | 1999-08-27 | 2003-03-04 | リガンド・ファーマシューティカルズ・インコーポレイテッド | アンドロゲンレセプターモジュレーターとしての８−置換−６−トリフルオロメチル−９−ピリド［３，２−ｇ］キノリン化合物 |
| PE20010647A1 (es) | 1999-09-14 | 2001-06-23 | Lilly Co Eli | Moduladores de receptores de retinoide x (rxr) con perfil farmacologico mejorado |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| AU2004266160A1 (en) | 2003-08-22 | 2005-03-03 | Ligand Pharmaceuticals Incorporated | 6-cycloamino-2-quinolinone derivatives as androgen receptor modulator compounds |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| US7879802B2 (en) | 2007-06-04 | 2011-02-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| AU2009256157B2 (en) | 2008-06-04 | 2014-12-18 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| JP2011528375A (ja) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CA3100941C (en) | 2011-03-01 | 2024-03-05 | Synergy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
| JP6499591B2 (ja) | 2013-02-25 | 2019-04-10 | シナジー ファーマシューティカルズ インコーポレイテッド | 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト |
| AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
| JP2016514671A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼのアゴニストおよびその使用 |
| AU2014274812B2 (en) | 2013-06-05 | 2018-09-27 | Bausch Health Ireland Limited | Ultra-pure agonists of guanylate cyclase C, method of making and using same |
| AU2014305843B2 (en) | 2013-08-09 | 2019-08-29 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| CN114340631A (zh) | 2019-05-21 | 2022-04-12 | 阿德利克斯股份有限公司 | 用于降低患者的血清磷酸盐的组合 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2616855A (en) * | 1948-01-15 | 1952-11-04 | Procter & Gamble | Detergent composition |
| US4329347A (en) * | 1978-02-17 | 1982-05-11 | Boehringer Ingelheim Gmbh | Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril |
| JPS5777676A (en) * | 1980-10-31 | 1982-05-15 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| PT79699B (en) * | 1983-12-22 | 1986-12-10 | Pfizer | Process for preparing quinolone inotropic agents |
| NZ212209A (en) * | 1984-05-29 | 1988-08-30 | Pfizer | Quinolone derivatives and pharmaceutical compositions |
| US4760064A (en) * | 1984-12-18 | 1988-07-26 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril compounds, compositions containing same and processes for preparing same |
| US4845100A (en) * | 1985-04-12 | 1989-07-04 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same |
| FR2580646A1 (fr) * | 1985-04-19 | 1986-10-24 | Synthelabo | Derives de 2(1h)-quinolinone, leur preparation et leur application en therapeutique |
| GB8529362D0 (en) * | 1985-11-28 | 1986-01-02 | Pfizer Ltd | Quinolone cardiac stimulants |
| DK111387A (da) * | 1986-03-05 | 1987-09-06 | Otsuka Pharma Co Ltd | Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne |
| US4886809A (en) * | 1986-07-31 | 1989-12-12 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof |
-
1986
- 1986-12-23 GB GB868630702A patent/GB8630702D0/en active Pending
-
1987
- 1987-12-21 MY MYPI87003231A patent/MY102277A/en unknown
- 1987-12-21 US US07/135,654 patent/US4937248A/en not_active Expired - Fee Related
- 1987-12-22 PH PH36289A patent/PH23448A/en unknown
- 1987-12-22 AU AU82933/87A patent/AU594220B2/en not_active Ceased
- 1987-12-22 NZ NZ223036A patent/NZ223036A/en unknown
- 1987-12-22 KR KR870014675A patent/KR880007514A/ko not_active Ceased
- 1987-12-22 JP JP62325121A patent/JPS63166866A/ja active Pending
- 1987-12-22 IE IE349087A patent/IE60619B1/en not_active IP Right Cessation
- 1987-12-22 FI FI875666A patent/FI90768C/fi not_active IP Right Cessation
- 1987-12-22 PT PT86448A patent/PT86448B/pt not_active IP Right Cessation
- 1987-12-22 AT AT87311275T patent/ATE65993T1/de active
- 1987-12-22 IL IL84917A patent/IL84917A/xx not_active IP Right Cessation
- 1987-12-22 ZA ZA879615A patent/ZA879615B/xx unknown
- 1987-12-22 CA CA000555175A patent/CA1318671C/en not_active Expired - Fee Related
- 1987-12-22 ES ES198787311275T patent/ES2029842T3/es not_active Expired - Lifetime
- 1987-12-22 DE DE8787311275T patent/DE3772015D1/de not_active Expired - Fee Related
- 1987-12-22 HU HU875962A patent/HU196991B/hu not_active IP Right Cessation
- 1987-12-22 DK DK680887A patent/DK163429C/da not_active IP Right Cessation
- 1987-12-22 EP EP87311275A patent/EP0272910B1/de not_active Expired - Lifetime
-
1991
- 1991-08-08 GR GR91401029T patent/GR3002445T3/el unknown
-
1992
- 1992-06-29 MX MX9203788A patent/MX9203788A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MY102277A (en) | 1992-05-15 |
| IE60619B1 (en) | 1994-07-27 |
| IL84917A (en) | 1991-08-16 |
| JPS63166866A (ja) | 1988-07-11 |
| FI875666A0 (fi) | 1987-12-22 |
| DE3772015D1 (de) | 1991-09-12 |
| CA1318671C (en) | 1993-06-01 |
| ZA879615B (en) | 1989-08-30 |
| EP0272910B1 (de) | 1991-08-07 |
| GR3002445T3 (en) | 1992-12-30 |
| US4937248A (en) | 1990-06-26 |
| FI90768C (fi) | 1994-03-25 |
| GB8630702D0 (en) | 1987-02-04 |
| HUT45984A (en) | 1988-09-28 |
| ES2029842T3 (es) | 1992-10-01 |
| PH23448A (en) | 1989-08-07 |
| AU594220B2 (en) | 1990-03-01 |
| IL84917A0 (en) | 1988-06-30 |
| DK163429C (da) | 1992-07-20 |
| PT86448B (pt) | 1990-11-20 |
| HU196991B (en) | 1989-02-28 |
| MX9203788A (es) | 1992-07-01 |
| EP0272910A1 (de) | 1988-06-29 |
| KR880007514A (ko) | 1988-08-27 |
| AU8293387A (en) | 1988-06-23 |
| NZ223036A (en) | 1990-11-27 |
| PT86448A (en) | 1988-01-01 |
| DK680887D0 (da) | 1987-12-22 |
| FI875666L (fi) | 1988-06-24 |
| DK680887A (da) | 1988-06-24 |
| IE873490L (en) | 1988-06-23 |
| FI90768B (fi) | 1993-12-15 |
| DK163429B (da) | 1992-03-02 |
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