ATE65993T1 - Chinolinverbindung. - Google Patents
Chinolinverbindung.Info
- Publication number
- ATE65993T1 ATE65993T1 AT87311275T AT87311275T ATE65993T1 AT E65993 T1 ATE65993 T1 AT E65993T1 AT 87311275 T AT87311275 T AT 87311275T AT 87311275 T AT87311275 T AT 87311275T AT E65993 T1 ATE65993 T1 AT E65993T1
- Authority
- AT
- Austria
- Prior art keywords
- quinoline compound
- compound
- quinoline
- concerned
- chem
- Prior art date
Links
- -1 QUINOLINE COMPOUND Chemical class 0.000 title 1
- SMWDFEZZVXVKRB-UHFFFAOYSA-N anhydrous quinoline Natural products N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Quinoline Compounds (AREA)
- Carbon And Carbon Compounds (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Secondary Cells (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868630702A GB8630702D0 (en) | 1986-12-23 | 1986-12-23 | Quinoline compound |
| EP87311275A EP0272910B1 (de) | 1986-12-23 | 1987-12-22 | Chinolinverbindung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE65993T1 true ATE65993T1 (de) | 1991-08-15 |
Family
ID=10609475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87311275T ATE65993T1 (de) | 1986-12-23 | 1987-12-22 | Chinolinverbindung. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4937248A (de) |
| EP (1) | EP0272910B1 (de) |
| JP (1) | JPS63166866A (de) |
| KR (1) | KR880007514A (de) |
| AT (1) | ATE65993T1 (de) |
| AU (1) | AU594220B2 (de) |
| CA (1) | CA1318671C (de) |
| DE (1) | DE3772015D1 (de) |
| DK (1) | DK163429C (de) |
| ES (1) | ES2029842T3 (de) |
| FI (1) | FI90768C (de) |
| GB (1) | GB8630702D0 (de) |
| GR (1) | GR3002445T3 (de) |
| HU (1) | HU196991B (de) |
| IE (1) | IE60619B1 (de) |
| IL (1) | IL84917A (de) |
| MX (1) | MX9203788A (de) |
| MY (1) | MY102277A (de) |
| NZ (1) | NZ223036A (de) |
| PH (1) | PH23448A (de) |
| PT (1) | PT86448B (de) |
| ZA (1) | ZA879615B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5166160A (en) * | 1986-12-23 | 1992-11-24 | Burroughs Wellcome Co. | Quinoline compound |
| GB8820174D0 (en) * | 1988-08-25 | 1988-09-28 | Wellcome Found | Quinoline compound |
| CA2304849A1 (en) * | 1997-09-24 | 1999-04-01 | Orion Corporation | Bisethers of 1-oxa, aza and thianaphthalen-2-ones as phospholamban inhibitors |
| MXPA02002032A (es) | 1999-08-27 | 2003-05-19 | Ligand Pharm Inc | Compuestos moduladores del receptor de androgeno y metodos. |
| EP1212322A2 (de) | 1999-08-27 | 2002-06-12 | Ligand Pharmaceuticals Incorporated | 8-substituierte-6-trifluoromethyl-9-pyrido[3,2-g]chiolinverbindungen als androgen rezeptormodulatoren |
| US6566372B1 (en) | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
| US6593493B1 (en) | 1999-09-14 | 2003-07-15 | Ligand Pharmaceuticals, Inc. | RXR modulators with improved pharmacologic profile |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| BRPI0413820A (pt) | 2003-08-22 | 2006-10-24 | Ligand Pharm Inc | derivados de 6-cicloamino-2-quinolinona como compostos moduladores de receptor de androgênio |
| WO2008151257A2 (en) | 2007-06-04 | 2008-12-11 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| ES2627848T3 (es) | 2008-06-04 | 2017-07-31 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| MX357121B (es) | 2011-03-01 | 2018-06-27 | Synergy Pharmaceuticals Inc Star | Proceso de preparacion de agonistas c de guanilato ciclasa. |
| EP2958577A2 (de) | 2013-02-25 | 2015-12-30 | Synergy Pharmaceuticals Inc. | Guanylat-cyclase-rezeptoragonisten zur verwendung bei der darmreinigung |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| EP2968439A2 (de) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Zusammensetzungen zur behandlung von magen-darm-störungen |
| PL3004138T3 (pl) | 2013-06-05 | 2024-07-29 | Bausch Health Ireland Limited | Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie |
| CA2920856C (en) | 2013-08-09 | 2026-03-03 | Ardelyx, Inc. | Ph modulating compounds for inhibiting gastrointestinal phosphate uptake |
| JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス， インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2616855A (en) * | 1948-01-15 | 1952-11-04 | Procter & Gamble | Detergent composition |
| US4329347A (en) * | 1978-02-17 | 1982-05-11 | Boehringer Ingelheim Gmbh | Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril |
| JPS5777676A (en) * | 1980-10-31 | 1982-05-15 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| US4710507A (en) * | 1983-12-22 | 1987-12-01 | Pfizer Inc. | Quinolone inotropic agents |
| PT80533B (en) * | 1984-05-29 | 1987-04-06 | Pfizer | Process for preparing quinolone inotropic agents |
| US4760064A (en) * | 1984-12-18 | 1988-07-26 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril compounds, compositions containing same and processes for preparing same |
| US4845100A (en) * | 1985-04-12 | 1989-07-04 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same |
| FR2580646A1 (fr) * | 1985-04-19 | 1986-10-24 | Synthelabo | Derives de 2(1h)-quinolinone, leur preparation et leur application en therapeutique |
| GB8529362D0 (en) * | 1985-11-28 | 1986-01-02 | Pfizer Ltd | Quinolone cardiac stimulants |
| DK111387A (da) * | 1986-03-05 | 1987-09-06 | Otsuka Pharma Co Ltd | Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne |
| EP0255134B1 (de) * | 1986-07-31 | 1993-03-03 | Otsuka Pharmaceutical Co., Ltd. | Karbostyril-Derivate und ihre Salze, Verfahren zu ihrer Herstellung und diese enthaltende kardiotonische Zusammensetzung |
-
1986
- 1986-12-23 GB GB868630702A patent/GB8630702D0/en active Pending
-
1987
- 1987-12-21 US US07/135,654 patent/US4937248A/en not_active Expired - Fee Related
- 1987-12-21 MY MYPI87003231A patent/MY102277A/en unknown
- 1987-12-22 DK DK680887A patent/DK163429C/da not_active IP Right Cessation
- 1987-12-22 HU HU875962A patent/HU196991B/hu not_active IP Right Cessation
- 1987-12-22 NZ NZ223036A patent/NZ223036A/en unknown
- 1987-12-22 AU AU82933/87A patent/AU594220B2/en not_active Ceased
- 1987-12-22 PT PT86448A patent/PT86448B/pt not_active IP Right Cessation
- 1987-12-22 ES ES198787311275T patent/ES2029842T3/es not_active Expired - Lifetime
- 1987-12-22 IE IE349087A patent/IE60619B1/en not_active IP Right Cessation
- 1987-12-22 PH PH36289A patent/PH23448A/en unknown
- 1987-12-22 IL IL84917A patent/IL84917A/xx not_active IP Right Cessation
- 1987-12-22 ZA ZA879615A patent/ZA879615B/xx unknown
- 1987-12-22 EP EP87311275A patent/EP0272910B1/de not_active Expired - Lifetime
- 1987-12-22 AT AT87311275T patent/ATE65993T1/de active
- 1987-12-22 JP JP62325121A patent/JPS63166866A/ja active Pending
- 1987-12-22 KR KR870014675A patent/KR880007514A/ko not_active Ceased
- 1987-12-22 FI FI875666A patent/FI90768C/fi not_active IP Right Cessation
- 1987-12-22 CA CA000555175A patent/CA1318671C/en not_active Expired - Fee Related
- 1987-12-22 DE DE8787311275T patent/DE3772015D1/de not_active Expired - Fee Related
-
1991
- 1991-08-08 GR GR91401029T patent/GR3002445T3/el unknown
-
1992
- 1992-06-29 MX MX9203788A patent/MX9203788A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI90768B (fi) | 1993-12-15 |
| FI875666L (fi) | 1988-06-24 |
| DK680887D0 (da) | 1987-12-22 |
| FI90768C (fi) | 1994-03-25 |
| ES2029842T3 (es) | 1992-10-01 |
| IL84917A (en) | 1991-08-16 |
| ZA879615B (en) | 1989-08-30 |
| EP0272910A1 (de) | 1988-06-29 |
| PT86448B (pt) | 1990-11-20 |
| PH23448A (en) | 1989-08-07 |
| GB8630702D0 (en) | 1987-02-04 |
| DK163429B (da) | 1992-03-02 |
| AU8293387A (en) | 1988-06-23 |
| AU594220B2 (en) | 1990-03-01 |
| CA1318671C (en) | 1993-06-01 |
| DK163429C (da) | 1992-07-20 |
| DE3772015D1 (de) | 1991-09-12 |
| KR880007514A (ko) | 1988-08-27 |
| US4937248A (en) | 1990-06-26 |
| EP0272910B1 (de) | 1991-08-07 |
| NZ223036A (en) | 1990-11-27 |
| GR3002445T3 (en) | 1992-12-30 |
| FI875666A0 (fi) | 1987-12-22 |
| JPS63166866A (ja) | 1988-07-11 |
| MY102277A (en) | 1992-05-15 |
| IE60619B1 (en) | 1994-07-27 |
| HUT45984A (en) | 1988-09-28 |
| IE873490L (en) | 1988-06-23 |
| MX9203788A (es) | 1992-07-01 |
| HU196991B (en) | 1989-02-28 |
| IL84917A0 (en) | 1988-06-30 |
| DK680887A (da) | 1988-06-24 |
| PT86448A (en) | 1988-01-01 |
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