PH23286A - Novel 80-acylaminoergolines - Google Patents

Novel 80-acylaminoergolines

Info

Publication number
PH23286A
PH23286A PH31714A PH31714A PH23286A PH 23286 A PH23286 A PH 23286A PH 31714 A PH31714 A PH 31714A PH 31714 A PH31714 A PH 31714A PH 23286 A PH23286 A PH 23286A
Authority
PH
Philippines
Prior art keywords
acylaminoergolines
novel
Prior art date
Application number
PH31714A
Other languages
English (en)
Inventor
Walter Haefliger
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of PH23286A publication Critical patent/PH23286A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH31714A 1984-01-12 1985-01-14 Novel 80-acylaminoergolines PH23286A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3400853 1984-01-12

Publications (1)

Publication Number Publication Date
PH23286A true PH23286A (en) 1989-06-30

Family

ID=6224786

Family Applications (1)

Application Number Title Priority Date Filing Date
PH31714A PH23286A (en) 1984-01-12 1985-01-14 Novel 80-acylaminoergolines

Country Status (28)

Country Link
US (2) US4950672A (cs)
JP (1) JPH0655739B2 (cs)
AT (1) AT391317B (cs)
AU (3) AU583489B2 (cs)
BE (1) BE901456A (cs)
CA (1) CA1245640A (cs)
CH (1) CH664568A5 (cs)
CY (1) CY1542A (cs)
DE (1) DE3500251C2 (cs)
DK (1) DK169891B1 (cs)
ES (1) ES8605514A1 (cs)
FI (1) FI82466C (cs)
FR (1) FR2560196B1 (cs)
GB (1) GB2152507B (cs)
GR (1) GR850065B (cs)
HK (1) HK48590A (cs)
HU (1) HU197569B (cs)
IE (1) IE58228B1 (cs)
IL (1) IL74043A (cs)
IT (1) IT1214648B (cs)
LU (1) LU85725A1 (cs)
NL (1) NL193541C (cs)
NZ (1) NZ210818A (cs)
PH (1) PH23286A (cs)
PT (1) PT79818B (cs)
SE (1) SE460420B (cs)
SG (1) SG32390G (cs)
ZA (1) ZA85276B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU197569B (en) * 1984-01-12 1989-04-28 Sandoz Ag Process for producing 8alpha-acylaminoergoline derivatives and pharmaceuticals comprising such compounds
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
NL8700046A (nl) * 1986-01-24 1987-08-17 Sandoz Ag 8 alfa-acylaminoergolinen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
US4981859A (en) * 1987-06-15 1991-01-01 Cycloalkylamides of (8 beta )-1-alkyl-6-(substituted)ergolines
US4931447A (en) * 1987-06-15 1990-06-05 Eli Lilly And Company Cycloalkylamides of (8β)-1-alkyl-6-(substituted) ergolines
IT1219652B (it) * 1987-06-23 1990-05-24 Sandoz Ag 8-acilamminoergolina,la sua preparazione e il suo impiego come medicamneto
DE3820159A1 (de) * 1987-06-23 1989-01-05 Sandoz Ag 8(alpha)-acylaminoergolin, seine herstellung und dieses enthaltende arzneimittel
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
GB8824744D0 (en) * 1988-10-21 1988-11-30 Erba Carlo Spa Antiemesis ergoline derivatives
DE3915950A1 (de) * 1989-05-12 1990-11-15 Schering Ag 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
HK1248215A1 (zh) 2015-01-20 2018-10-12 Xoc Pharmaceuticals, Inc 麦角灵化合物及其用途
WO2016118539A2 (en) * 2015-01-20 2016-07-28 Xoc Pharmaceuticls, Inc. Isoergoline compounds and uses thereof
EP3630758A1 (en) 2017-06-01 2020-04-08 Xoc Pharmaceuticals, Inc Ergoline derivatives for use in medicine

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3218323A (en) * 1965-11-16 Esters of i,g-dimethyl-b-ergolenyl carbamic acid
US2864822A (en) * 1956-10-22 1958-12-16 Lilly Co Eli 9-amino-7-methyl-belta10-ergolene and derivatives thereof
CH622519A5 (en) * 1974-07-05 1981-04-15 Hoechst Ag Process for the preparation of hydroxyalkylxanthines
US4348392A (en) * 1974-07-19 1982-09-07 Sandoz Ltd. 8α-Substituted ergoline-I derivatives
GB1517973A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
US3922347A (en) * 1974-12-19 1975-11-25 Lilly Co Eli Method of inhibiting prolactin secretion with 8-acylaminoergolenes
CH615929A5 (en) * 1975-06-02 1980-02-29 Sandoz Ag Process for the preparation of novel ergoline compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
CH622518A5 (en) * 1976-12-14 1981-04-15 Sandoz Ag Process for the preparation of novel ergoline compounds
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
HU197569B (en) * 1984-01-12 1989-04-28 Sandoz Ag Process for producing 8alpha-acylaminoergoline derivatives and pharmaceuticals comprising such compounds
HU195810B (en) * 1984-12-24 1988-07-28 Sandoz Ag Process for preparing new 8alpha-acyl-amino-ergoline derivatives and pharmaceutical compositions containing such compounds
IT1219652B (it) * 1987-06-23 1990-05-24 Sandoz Ag 8-acilamminoergolina,la sua preparazione e il suo impiego come medicamneto

Also Published As

Publication number Publication date
AU609539B2 (en) 1991-05-02
IT1214648B (it) 1990-01-18
SE460420B (sv) 1989-10-09
NL193541B (nl) 1999-09-01
JPS60174783A (ja) 1985-09-09
NL193541C (nl) 2000-01-04
FI82466C (fi) 1991-03-11
DK12685D0 (da) 1985-01-10
NZ210818A (en) 1989-02-24
FR2560196A1 (fr) 1985-08-30
ATA5985A (de) 1990-03-15
AU583489B2 (en) 1989-05-04
IE58228B1 (en) 1993-08-11
BE901456A (fr) 1985-07-08
AU3760985A (en) 1985-07-18
GB2152507B (en) 1987-07-15
AU2506788A (en) 1989-03-02
DK169891B1 (da) 1995-03-27
HK48590A (en) 1990-06-29
AU2506688A (en) 1989-02-23
CY1542A (en) 1991-03-22
FI850130A0 (fi) 1985-01-11
CH664568A5 (de) 1988-03-15
SE8500107L (sv) 1985-07-13
GB8500454D0 (en) 1985-02-13
PT79818B (en) 1987-01-07
HU197569B (en) 1989-04-28
LU85725A1 (fr) 1985-10-22
ES8605514A1 (es) 1986-03-16
AU618290B2 (en) 1991-12-19
FI82466B (fi) 1990-11-30
PT79818A (en) 1985-02-01
ES539511A0 (es) 1986-03-16
GB2152507A (en) 1985-08-07
GR850065B (cs) 1985-05-03
DK12685A (da) 1985-07-13
IL74043A0 (en) 1985-04-30
SG32390G (en) 1990-08-03
ZA85276B (en) 1986-08-27
JPH0655739B2 (ja) 1994-07-27
DE3500251A1 (de) 1985-07-18
DE3500251C2 (de) 1995-01-26
SE8500107D0 (sv) 1985-01-10
US5077298A (en) 1991-12-31
FI850130L (fi) 1985-07-13
IT8547538A0 (it) 1985-01-11
US4950672A (en) 1990-08-21
FR2560196B1 (fr) 1986-07-18
CA1245640A (en) 1988-11-29
IL74043A (en) 1988-10-31
AT391317B (de) 1990-09-25
HUT37148A (en) 1985-11-28
NL8500008A (nl) 1985-08-01
IE850064L (en) 1985-07-12

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