PH12022551000A1 - Directed conjugation technologies - Google Patents
Directed conjugation technologiesInfo
- Publication number
- PH12022551000A1 PH12022551000A1 PH1/2022/551000A PH12022551000A PH12022551000A1 PH 12022551000 A1 PH12022551000 A1 PH 12022551000A1 PH 12022551000 A PH12022551000 A PH 12022551000A PH 12022551000 A1 PH12022551000 A1 PH 12022551000A1
- Authority
- PH
- Philippines
- Prior art keywords
- technologies
- directed conjugation
- present disclosure
- conjugation technologies
- directed
- Prior art date
Links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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| US202063063902P | 2020-08-10 | 2020-08-10 | |
| PCT/US2020/061127 WO2021102052A1 (en) | 2019-11-18 | 2020-11-18 | Directed conjugation technologies |
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| WO2022078566A1 (en) * | 2020-10-12 | 2022-04-21 | Debiopharm Research & Manufacturing S.A. | Reactive conjugates |
| MX2023013274A (es) * | 2021-05-17 | 2023-11-30 | Biohaven Therapeutics Ltd | Composiciones que incluyen potenciadores de tratamientos conjugados. |
| US20250108124A1 (en) * | 2021-05-19 | 2025-04-03 | Biohaven Therapeutics Ltd. | Antibody drug conjugates using mates technology for delivering cytotoxic agents |
| CN113636960A (zh) * | 2021-08-24 | 2021-11-12 | 上海皓元医药股份有限公司 | 一种2-(氯磺酰基)环己烷-1-烯甲酸乙酯衍生物的制备方法 |
| CN114085376B (zh) * | 2021-12-02 | 2022-12-20 | 中国科学院长春应用化学研究所 | 一种多肽及其制备方法、双特异性抗体及其应用 |
| WO2025158412A1 (en) | 2024-01-26 | 2025-07-31 | Biohaven Therapeutics Ltd. | BIFUNCTIONAL DEGRADERS OF IgG4 IMMUNOGLOBULINS |
| WO2025181697A1 (en) | 2024-02-26 | 2025-09-04 | Biohaven Therapeutics Ltd. | Bifunctional degraders of anti-pla2r antibody |
| WO2025210538A1 (en) | 2024-04-02 | 2025-10-09 | Biohaven Therapeutics Ltd. | Bifunctional degraders |
| WO2026028159A1 (en) | 2024-07-31 | 2026-02-05 | Biohaven Therapeutics Ltd. | Bifunctional degraders for the treatment of graves' disease |
| WO2026028158A1 (en) | 2024-07-31 | 2026-02-05 | Biohaven Therapeutics Ltd. | Targeted degradation of anti-aav antibodies to enable aav-based gene therapy |
| WO2026083257A1 (en) | 2024-10-14 | 2026-04-23 | Biohaven Therapeutics Ltd. | Antigen-specific degraders of immunoglobulin a and their uses |
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| EP2861261A2 (en) * | 2012-06-19 | 2015-04-22 | Polytherics Limited | Process for preparation of antibody conjugates and antibody conjugates |
| GB201506407D0 (en) * | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
| WO2017139329A1 (en) * | 2016-02-09 | 2017-08-17 | Alexander Krantz | Site-selective functionalization of proteins using traceless affinity lables |
| US11135307B2 (en) * | 2016-11-23 | 2021-10-05 | Mersana Therapeutics, Inc. | Peptide-containing linkers for antibody-drug conjugates |
| AU2018259856B2 (en) * | 2017-04-28 | 2025-05-01 | Ajinomoto Co., Inc. | Compound having substance that has affinity for soluble protein, cleavable moiety, and reactive group, or salt thereof |
| CA3069986A1 (en) * | 2017-07-26 | 2019-01-31 | Kleo Pharmaceuticals, Inc. | Universal abt compounds and uses thereof |
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| AU2020388383A1 (en) | 2022-03-31 |
| EP4061425A1 (en) | 2022-09-28 |
| US20230128688A1 (en) | 2023-04-27 |
| MX2022005884A (es) | 2022-08-15 |
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