PH12020500622A1 - 17á-HYDROXYSTEROID DEHYDROGENASE TYPE 13 (HSD17B13) IRNA COMPOSITIONS AND METHODS OF USE THEREOF - Google Patents

17á-HYDROXYSTEROID DEHYDROGENASE TYPE 13 (HSD17B13) IRNA COMPOSITIONS AND METHODS OF USE THEREOF

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Publication number
PH12020500622A1
PH12020500622A1 PH12020500622A PH12020500622A PH12020500622A1 PH 12020500622 A1 PH12020500622 A1 PH 12020500622A1 PH 12020500622 A PH12020500622 A PH 12020500622A PH 12020500622 A PH12020500622 A PH 12020500622A PH 12020500622 A1 PH12020500622 A1 PH 12020500622A1
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PH
Philippines
Prior art keywords
hsd17b13
methods
hydroxysteroid dehydrogenase
dehydrogenase type
irna compositions
Prior art date
Application number
PH12020500622A
Other languages
English (en)
Inventor
Gregory Hinkle
Frederic Tremblay
Noura S Abul-Husn
Omri Gottesman
Alexander Li
Xiping Cheng
Yurong Xin
Jesper Gromada
Frederick E Dewey
Aris Baras
Alan Shuldiner
Stuart Milstein
Original Assignee
Regeneron Pharma
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=66001358&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH12020500622(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of PH12020500622A1 publication Critical patent/PH12020500622A1/en

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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12N2310/30—Chemical structure
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    • C12N2310/353—Nature of the modification linked to the nucleic acid via an atom other than carbon
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PH12020500622A 2018-03-21 2020-08-19 17á-HYDROXYSTEROID DEHYDROGENASE TYPE 13 (HSD17B13) IRNA COMPOSITIONS AND METHODS OF USE THEREOF PH12020500622A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862645941P 2018-03-21 2018-03-21
US201862770298P 2018-11-21 2018-11-21
US201862775590P 2018-12-05 2018-12-05
PCT/US2019/023079 WO2019183164A1 (en) 2018-03-21 2019-03-20 17β-HYDROXYSTEROID DEHYDROGENASE TYPE 13 (HSD17B13) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Publications (1)

Publication Number Publication Date
PH12020500622A1 true PH12020500622A1 (en) 2021-03-15

Family

ID=66001358

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12020500622A PH12020500622A1 (en) 2018-03-21 2020-08-19 17á-HYDROXYSTEROID DEHYDROGENASE TYPE 13 (HSD17B13) IRNA COMPOSITIONS AND METHODS OF USE THEREOF

Country Status (17)

Country Link
US (3) US12359201B2 (https=)
EP (1) EP3768838A1 (https=)
JP (3) JP7507093B2 (https=)
KR (2) KR20250154534A (https=)
CN (1) CN112020556A (https=)
AU (2) AU2019239971B2 (https=)
BR (1) BR112020018758A2 (https=)
CA (1) CA3091146A1 (https=)
CL (1) CL2020002401A1 (https=)
CO (1) CO2020010342A2 (https=)
IL (1) IL277329A (https=)
MX (2) MX2020009812A (https=)
MY (1) MY207352A (https=)
PH (1) PH12020500622A1 (https=)
SG (1) SG11202007583SA (https=)
TW (1) TWI877108B (https=)
WO (1) WO2019183164A1 (https=)

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TW202400791A (zh) * 2022-05-06 2024-01-01 大陸商蘇州瑞博生物技術股份有限公司 一種核酸、含有該核酸的組合物與綴合物及製備方法和用途
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