CO2020010342A2 - Composiciones de arni de 17 β -hidroxiesteroide deshidrogenasas tipo 13 (hsd17b13) y métodos de uso de las mismas - Google Patents

Composiciones de arni de 17 β -hidroxiesteroide deshidrogenasas tipo 13 (hsd17b13) y métodos de uso de las mismas

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Publication number
CO2020010342A2
CO2020010342A2 CONC2020/0010342A CO2020010342A CO2020010342A2 CO 2020010342 A2 CO2020010342 A2 CO 2020010342A2 CO 2020010342 A CO2020010342 A CO 2020010342A CO 2020010342 A2 CO2020010342 A2 CO 2020010342A2
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CO
Colombia
Prior art keywords
hsd17b13
methods
compositions
arni
hydroxysteroid dehydrogenases
Prior art date
Application number
CONC2020/0010342A
Other languages
English (en)
Inventor
Stuart Milstein
Gregory Hinkle
Frederic Tremblay
Noura S Abul-Husn
Omri Gottesman
Alexander Li
Xiping Cheng
Yurong Xin
Jesper Gromada
Frederick E Dewey
Aris Baras
Alan Shuldiner
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of CO2020010342A2 publication Critical patent/CO2020010342A2/es

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Abstract

RESUMEN Composiciones de ácidos ribonucleicos de hebra doble (ARNhd) dirigidos al gen HSD17B13, así como métodos para inhibir la expresión de HSD17B13, y métodos para tratar a sujetos que pudieran verse beneficiados con una reducción de la expresión de HSD17B13, tales como sujetos que padecen una enfermedad, trastorno o condición asociada con HSD17B13, mediante el uso de dichas composiciones de ARNhd.
CONC2020/0010342A 2018-03-21 2020-08-21 Composiciones de arni de 17 β -hidroxiesteroide deshidrogenasas tipo 13 (hsd17b13) y métodos de uso de las mismas CO2020010342A2 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862645941P 2018-03-21 2018-03-21
US201862770298P 2018-11-21 2018-11-21
US201862775590P 2018-12-05 2018-12-05
PCT/US2019/023079 WO2019183164A1 (en) 2018-03-21 2019-03-20 17β-HYDROXYSTEROID DEHYDROGENASE TYPE 13 (HSD17B13) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Publications (1)

Publication Number Publication Date
CO2020010342A2 true CO2020010342A2 (es) 2020-08-31

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Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2020/0010342A CO2020010342A2 (es) 2018-03-21 2020-08-21 Composiciones de arni de 17 β -hidroxiesteroide deshidrogenasas tipo 13 (hsd17b13) y métodos de uso de las mismas

Country Status (16)

Country Link
US (2) US20210380985A1 (es)
EP (1) EP3768838A1 (es)
JP (2) JP7507093B2 (es)
KR (1) KR20200133373A (es)
CN (1) CN112020556A (es)
AU (1) AU2019239971A1 (es)
BR (1) BR112020018758A2 (es)
CA (1) CA3091146A1 (es)
CL (1) CL2020002401A1 (es)
CO (1) CO2020010342A2 (es)
IL (1) IL277329A (es)
MX (1) MX2020009812A (es)
PH (1) PH12020500622A1 (es)
SG (1) SG11202007583SA (es)
TW (1) TW202003848A (es)
WO (1) WO2019183164A1 (es)

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MX2020009812A (es) 2021-01-08
EP3768838A1 (en) 2021-01-27
IL277329A (en) 2020-10-29
US20210380985A1 (en) 2021-12-09
JP7507093B2 (ja) 2024-06-27
AU2019239971A1 (en) 2020-09-03
CA3091146A1 (en) 2019-09-26
JP2024105396A (ja) 2024-08-06
KR20200133373A (ko) 2020-11-27
PH12020500622A1 (en) 2021-03-15
JP2021518125A (ja) 2021-08-02
TW202003848A (zh) 2020-01-16
US11180757B1 (en) 2021-11-23
BR112020018758A2 (pt) 2021-01-26
CN112020556A (zh) 2020-12-01
CL2020002401A1 (es) 2021-01-29
WO2019183164A1 (en) 2019-09-26
SG11202007583SA (en) 2020-09-29

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