PH12016501912A1 - Apolipoprotein a-i mimics - Google Patents
Apolipoprotein a-i mimicsInfo
- Publication number
- PH12016501912A1 PH12016501912A1 PH12016501912A PH12016501912A PH12016501912A1 PH 12016501912 A1 PH12016501912 A1 PH 12016501912A1 PH 12016501912 A PH12016501912 A PH 12016501912A PH 12016501912 A PH12016501912 A PH 12016501912A PH 12016501912 A1 PH12016501912 A1 PH 12016501912A1
- Authority
- PH
- Philippines
- Prior art keywords
- apolipoprotein
- mimics
- disorder
- peptides
- compositions
- Prior art date
Links
- 102000005666 Apolipoprotein A-I Human genes 0.000 title 1
- 108010059886 Apolipoprotein A-I Proteins 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 1
- 206010048554 Endothelial dysfunction Diseases 0.000 abstract 1
- 208000017170 Lipid metabolism disease Diseases 0.000 abstract 1
- 230000008694 endothelial dysfunction Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15296009P | 2009-02-16 | 2009-02-16 | |
| US15296609P | 2009-02-16 | 2009-02-16 | |
| US15296209P | 2009-02-16 | 2009-02-16 | |
| PCT/US2010/024096 WO2010093918A1 (en) | 2009-02-16 | 2010-02-12 | Apolipoprotein a-i mimics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12016501912A1 true PH12016501912A1 (en) | 2019-11-18 |
Family
ID=42562076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12016501912A PH12016501912A1 (en) | 2009-02-16 | 2016-09-27 | Apolipoprotein a-i mimics |
Country Status (26)
| Country | Link |
|---|---|
| US (4) | US8378068B2 (enExample) |
| EP (2) | EP2939683B1 (enExample) |
| JP (2) | JP5719783B2 (enExample) |
| KR (1) | KR101688547B1 (enExample) |
| CN (2) | CN102395375B (enExample) |
| AU (1) | AU2010213568B2 (enExample) |
| CA (2) | CA2982157A1 (enExample) |
| CY (1) | CY1118809T1 (enExample) |
| DK (2) | DK2396017T3 (enExample) |
| ES (2) | ES2620478T3 (enExample) |
| HK (1) | HK1209436A1 (enExample) |
| HR (2) | HRP20150998T1 (enExample) |
| HU (2) | HUE026062T2 (enExample) |
| IL (2) | IL214576B (enExample) |
| LT (1) | LT2939683T (enExample) |
| MX (3) | MX343654B (enExample) |
| NZ (1) | NZ594516A (enExample) |
| PH (1) | PH12016501912A1 (enExample) |
| PL (2) | PL2396017T3 (enExample) |
| PT (2) | PT2939683T (enExample) |
| RU (2) | RU2532222C2 (enExample) |
| SG (1) | SG173624A1 (enExample) |
| SI (2) | SI2939683T1 (enExample) |
| SM (2) | SMT201700203T1 (enExample) |
| WO (1) | WO2010093918A1 (enExample) |
| ZA (1) | ZA201105997B (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8163699B2 (en) * | 2006-06-01 | 2012-04-24 | Montreal Heart Institute | Method for the treatment of valvular disease |
| US20120141576A1 (en) * | 2007-03-15 | 2012-06-07 | Benjamin Johnson | Treatment of Dermatologic Skin Disorders |
| WO2008141230A1 (en) | 2007-05-09 | 2008-11-20 | Lawrence Livermore National Security, Llc | Methods and systems for monitoring production of a target protein in a nanolipoprotein particle |
| US9688718B2 (en) | 2008-01-11 | 2017-06-27 | Lawrence Livermore National Security, Llc | Nanolipoprotein particles comprising hydrogenases and related products, methods and systems |
| DK2396017T3 (en) | 2009-02-16 | 2015-09-14 | Cerenis Therapeutics Holding Sa | Apolipoprotein A-I-mimetika |
| ES2648788T3 (es) | 2011-01-26 | 2018-01-08 | Inserm - Institut National De La Santé Et De La Recherche Médicale | Método para evaluar el riesgo de un sujeto de tener una enfermedad cardiovascular |
| HUE042314T2 (hu) | 2011-02-07 | 2019-06-28 | Cerenis Therapeutics Holding Sa | Lipoprotein komplexek és azok gyártása és alkalmazásai |
| AU2015271986B2 (en) * | 2011-02-07 | 2018-02-22 | Cerenis Therapeutics Holding Sa | Lipoprotein complexes and manufacturing and uses thereof |
| US9644038B2 (en) | 2011-12-21 | 2017-05-09 | The Regents Of The University Of California | Apolipoprotein nanodiscs with telodendrimer |
| WO2013188879A1 (en) | 2012-06-16 | 2013-12-19 | Atherotech, Inc. | Measurement of serum lipoproteins |
| US9239280B2 (en) * | 2012-06-16 | 2016-01-19 | Atherotech, Inc. | Measurement of serum lipoproteins |
| MX2016014306A (es) | 2014-05-02 | 2017-06-12 | Cerenis Therapeutics Holding Sa | Marcadores para terapia con lipoproteinas de alta densidad (hdl). |
| WO2016049061A1 (en) | 2014-09-22 | 2016-03-31 | Lawrence Livermore National Security, Llc | Electrochemical flow-cell for hydrogen production and nicotinamide co-factor dependent target reduction, and related methods and systems |
| EP3273944B1 (en) | 2015-03-25 | 2024-11-20 | The Regents of The University of Michigan | Compositions and methods for delivery of biomacromolecule agents |
| WO2017035326A1 (en) | 2015-08-25 | 2017-03-02 | Lawrence Livermore National Security, Llc | Stable nanolipoprotein particles and related compositions methods and systems |
| WO2017044899A1 (en) * | 2015-09-11 | 2017-03-16 | Lawrence Livermore National Security, Llc | Synthetic apolipoproteins, and related compositions methods and systems for nanolipoprotein particles formation |
| US20190201540A1 (en) * | 2016-05-24 | 2019-07-04 | Stc Unm | Immunogens, compositions, and methods for treating dyslipidemia |
| US12083223B2 (en) | 2017-05-02 | 2024-09-10 | Lawrence Livermore National Security, Llc | Nanolipoprotein particles and related compositions methods and systems for loading RNA |
| WO2018204421A2 (en) | 2017-05-02 | 2018-11-08 | Lawrence Livermore National Security, Llc | Momp telonanoparticles, and related compositions, methods and systems |
| TW201919686A (zh) * | 2017-08-10 | 2019-06-01 | 法商塞勒尼斯醫療控股公司 | 脫輔基子(apomers) |
| WO2019030574A1 (en) * | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | Cargomers |
| WO2021209808A1 (en) * | 2020-04-16 | 2021-10-21 | Abionyx Pharma Sa | Cer-001 therapy for treating kidney disease |
| CN115666720A (zh) | 2020-04-16 | 2023-01-31 | 阿比奥尼克斯制药公司 | 用于治疗肾病的cer-001疗法 |
| EP4135747A1 (en) | 2020-04-16 | 2023-02-22 | Abionyx Pharma SA | Methods for treating acute conditions using lipid binding protein- based complexes |
| JP2023543498A (ja) | 2020-10-01 | 2023-10-16 | アビオニクス ファーマ エスエー | 脂質結合タンパク質ベースの複合体を使用した、眼疾患を治療するための方法 |
| EP4259280A4 (en) * | 2020-12-11 | 2025-02-12 | The Regents Of The University Of Michigan | Compositions and methods for preventing, attenuating, and treating medical conditions with shdl nanoparticles |
| JP2024514154A (ja) | 2021-04-15 | 2024-03-28 | アビオニクス ファーマ エスエー | 臓器保存溶液における脂質結合タンパク質ベースの複合体の使用 |
| CN114940711B (zh) * | 2021-10-25 | 2023-05-12 | 中山大学 | 载脂蛋白a-i模拟肽及其应用 |
| EP4504150A1 (en) | 2022-04-06 | 2025-02-12 | Abionyx Pharma SA | Methods for treating eye diseases using lipid binding protein-based complexes |
| EP4504233A1 (en) | 2022-04-06 | 2025-02-12 | Abionyx Pharma SA | Methods for treating leukocytosis, endothelial dysfunction and carditis using lipid binding protein-based complexes |
| CN120344255A (zh) | 2022-06-10 | 2025-07-18 | 阿比奥尼克斯制药公司 | 使用基于脂质结合蛋白的复合物治疗过度炎性病症的方法 |
| EP4536269A2 (en) | 2022-06-10 | 2025-04-16 | Abionyx Pharma SA | Methods for treating acute conditions using lipid binding protein-based complexes |
| US12060148B2 (en) | 2022-08-16 | 2024-08-13 | Honeywell International Inc. | Ground resonance detection and warning system and method |
| AU2024207875A1 (en) | 2023-01-13 | 2025-07-24 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
| WO2025093929A1 (en) | 2023-10-31 | 2025-05-08 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
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| FR2734568B1 (fr) | 1995-05-22 | 1997-06-20 | Rhone Poulenc Rorer Sa | Nouveaux variants de l'apolipoproteine |
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| US6518412B1 (en) * | 1997-09-29 | 2003-02-11 | Jean-Louis Dasseux | Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
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| TW200744627A (en) | 2006-02-21 | 2007-12-16 | Pfizer Prod Inc | Methods for the treatment of macular degeneration and related eye conditions |
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| US20080138284A1 (en) * | 2006-09-26 | 2008-06-12 | Lipid Sciences, Inc. | Novel Peptides That Promote Lipid Efflux |
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| US7956035B2 (en) | 2007-03-01 | 2011-06-07 | Csl Limited | Treatment of endothelial dysfunction in diabetic patients |
| AU2008266753A1 (en) | 2007-06-20 | 2008-12-24 | Istituto Di Recerche Di Biologia Molecolare P. Angeletti S.P.A. | ApoA-1 peptide mimetics |
| US9173890B2 (en) * | 2007-09-20 | 2015-11-03 | Abbott Cardiovascular Systems Inc. | Sustained release of Apo A-I mimetic peptides and methods of treatment |
| WO2010083611A1 (en) | 2009-01-23 | 2010-07-29 | Institut De Cardiologie De Montreal | Method for the prevention and treatment of diastolic dysfunction employing an apolipoproteina1 (apoa1) mimetic peptide/phospholipid complex |
| DK2396017T3 (en) | 2009-02-16 | 2015-09-14 | Cerenis Therapeutics Holding Sa | Apolipoprotein A-I-mimetika |
| US20130197226A1 (en) * | 2010-07-28 | 2013-08-01 | Jean-Claude Tardif | Pharmaceutical compositions for the treatment of left ventricular diastolic dysfunction comprising an apolipoprotein peptide/phospholipid complex |
| CN105051051B (zh) | 2013-03-15 | 2021-07-16 | 萨瑞斯治疗控股公司 | 用于合成神经鞘磷脂和二氢神经鞘磷脂的方法 |
| US9708354B2 (en) | 2013-03-15 | 2017-07-18 | Cerenis Therapeutics Holding Sa | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
-
2010
- 2010-02-12 DK DK10741801.4T patent/DK2396017T3/en active
- 2010-02-12 HR HRP20150998TT patent/HRP20150998T1/hr unknown
- 2010-02-12 SG SG2011057569A patent/SG173624A1/en unknown
- 2010-02-12 NZ NZ594516A patent/NZ594516A/xx not_active IP Right Cessation
- 2010-02-12 EP EP15157397.9A patent/EP2939683B1/en active Active
- 2010-02-12 ES ES15157397.9T patent/ES2620478T3/es active Active
- 2010-02-12 AU AU2010213568A patent/AU2010213568B2/en active Active
- 2010-02-12 MX MX2014006888A patent/MX343654B/es unknown
- 2010-02-12 PL PL10741801T patent/PL2396017T3/pl unknown
- 2010-02-12 SM SM20170203T patent/SMT201700203T1/it unknown
- 2010-02-12 DK DK15157397.9T patent/DK2939683T3/en active
- 2010-02-12 PT PT151573979T patent/PT2939683T/pt unknown
- 2010-02-12 MX MX2011008599A patent/MX2011008599A/es active IP Right Grant
- 2010-02-12 ES ES10741801.4T patent/ES2554853T3/es active Active
- 2010-02-12 US US12/705,094 patent/US8378068B2/en active Active
- 2010-02-12 WO PCT/US2010/024096 patent/WO2010093918A1/en not_active Ceased
- 2010-02-12 LT LTEP15157397.9T patent/LT2939683T/lt unknown
- 2010-02-12 RU RU2011138011/10A patent/RU2532222C2/ru not_active IP Right Cessation
- 2010-02-12 SI SI201031428A patent/SI2939683T1/sl unknown
- 2010-02-12 CA CA2982157A patent/CA2982157A1/en not_active Abandoned
- 2010-02-12 PT PT107418014T patent/PT2396017E/pt unknown
- 2010-02-12 PL PL15157397T patent/PL2939683T3/pl unknown
- 2010-02-12 CN CN201080016764.XA patent/CN102395375B/zh active Active
- 2010-02-12 EP EP10741801.4A patent/EP2396017B1/en active Active
- 2010-02-12 HU HUE10741801A patent/HUE026062T2/en unknown
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