PH12015502306A1 - Matrix metalloproteinases and uses thereof - Google Patents
Matrix metalloproteinases and uses thereofInfo
- Publication number
- PH12015502306A1 PH12015502306A1 PH12015502306A PH12015502306A PH12015502306A1 PH 12015502306 A1 PH12015502306 A1 PH 12015502306A1 PH 12015502306 A PH12015502306 A PH 12015502306A PH 12015502306 A PH12015502306 A PH 12015502306A PH 12015502306 A1 PH12015502306 A1 PH 12015502306A1
- Authority
- PH
- Philippines
- Prior art keywords
- mmp
- mmps
- inactive
- matrix metalloproteinases
- prommps
- Prior art date
Links
- 102000002274 Matrix Metalloproteinases Human genes 0.000 title abstract 10
- 108010000684 Matrix Metalloproteinases Proteins 0.000 title abstract 10
- 102100026799 Matrix metalloproteinase-28 Human genes 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- VKUYLANQOAKALN-UHFFFAOYSA-N 2-[benzyl-(4-methoxyphenyl)sulfonylamino]-n-hydroxy-4-methylpentanamide Chemical compound C1=CC(OC)=CC=C1S(=O)(=O)N(C(CC(C)C)C(=O)NO)CC1=CC=CC=C1 VKUYLANQOAKALN-UHFFFAOYSA-N 0.000 abstract 1
- 102100026802 72 kDa type IV collagenase Human genes 0.000 abstract 1
- 101710151806 72 kDa type IV collagenase Proteins 0.000 abstract 1
- 102100027995 Collagenase 3 Human genes 0.000 abstract 1
- 108050005238 Collagenase 3 Proteins 0.000 abstract 1
- 102000010911 Enzyme Precursors Human genes 0.000 abstract 1
- 108010062466 Enzyme Precursors Proteins 0.000 abstract 1
- 101001011896 Homo sapiens Matrix metalloproteinase-19 Proteins 0.000 abstract 1
- 101000627854 Homo sapiens Matrix metalloproteinase-26 Proteins 0.000 abstract 1
- 101000627861 Homo sapiens Matrix metalloproteinase-28 Proteins 0.000 abstract 1
- 102100027998 Macrophage metalloelastase Human genes 0.000 abstract 1
- 101710187853 Macrophage metalloelastase Proteins 0.000 abstract 1
- 102100030417 Matrilysin Human genes 0.000 abstract 1
- 108090000855 Matrilysin Proteins 0.000 abstract 1
- 102000000380 Matrix Metalloproteinase 1 Human genes 0.000 abstract 1
- 108010016113 Matrix Metalloproteinase 1 Proteins 0.000 abstract 1
- 108010076557 Matrix Metalloproteinase 14 Proteins 0.000 abstract 1
- 102100030216 Matrix metalloproteinase-14 Human genes 0.000 abstract 1
- 102100030201 Matrix metalloproteinase-15 Human genes 0.000 abstract 1
- 108090000560 Matrix metalloproteinase-15 Proteins 0.000 abstract 1
- 102100030200 Matrix metalloproteinase-16 Human genes 0.000 abstract 1
- 108090000561 Matrix metalloproteinase-16 Proteins 0.000 abstract 1
- 102100030219 Matrix metalloproteinase-17 Human genes 0.000 abstract 1
- 108090000585 Matrix metalloproteinase-17 Proteins 0.000 abstract 1
- 102100030218 Matrix metalloproteinase-19 Human genes 0.000 abstract 1
- 108090000587 Matrix metalloproteinase-19 Proteins 0.000 abstract 1
- 102000004055 Matrix metalloproteinase-19 Human genes 0.000 abstract 1
- 102100029693 Matrix metalloproteinase-20 Human genes 0.000 abstract 1
- 108090000609 Matrix metalloproteinase-20 Proteins 0.000 abstract 1
- 101710082411 Matrix metalloproteinase-21 Proteins 0.000 abstract 1
- 102100024130 Matrix metalloproteinase-23 Human genes 0.000 abstract 1
- 102100024129 Matrix metalloproteinase-24 Human genes 0.000 abstract 1
- 108050005214 Matrix metalloproteinase-24 Proteins 0.000 abstract 1
- 102100024128 Matrix metalloproteinase-26 Human genes 0.000 abstract 1
- 102100024132 Matrix metalloproteinase-27 Human genes 0.000 abstract 1
- 108050005201 Matrix metalloproteinase-27 Proteins 0.000 abstract 1
- 102100030412 Matrix metalloproteinase-9 Human genes 0.000 abstract 1
- 108010015302 Matrix metalloproteinase-9 Proteins 0.000 abstract 1
- 102100030411 Neutrophil collagenase Human genes 0.000 abstract 1
- 101710118230 Neutrophil collagenase Proteins 0.000 abstract 1
- 102100030416 Stromelysin-1 Human genes 0.000 abstract 1
- 101710108790 Stromelysin-1 Proteins 0.000 abstract 1
- 102100028848 Stromelysin-2 Human genes 0.000 abstract 1
- 101710108792 Stromelysin-2 Proteins 0.000 abstract 1
- 102100028847 Stromelysin-3 Human genes 0.000 abstract 1
- 108050005271 Stromelysin-3 Proteins 0.000 abstract 1
- 101001011890 Xenopus laevis Matrix metalloproteinase-18 Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000010494 dissociation reaction Methods 0.000 abstract 1
- 230000005593 dissociations Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 108090000440 matrix metalloproteinase 25 Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
- C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
- C12N9/6416—Metalloendopeptidases (3.4.24)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24007—Interstitial collagenase (3.4.24.7), i.e. matrix metalloprotease 1 or MMP1
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24017—Stromelysin 1 (3.4.24.17)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24024—Gelatinase A (3.4.24.24), i.e. matrix metalloproteinase 2 or MMP2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24034—Neutrophil collagenase (3.4.24.34)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24035—Gelatinase B (3.4.24.35), i.e. matrix metalloprotease 9 or MMP9
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24065—Macrophage elastase (3.4.24.65), i.e. metalloelastase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361808861P | 2013-04-05 | 2013-04-05 | |
| PCT/US2014/033009 WO2014165780A2 (en) | 2013-04-05 | 2014-04-04 | Matrix metalloproteinases and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12015502306A1 true PH12015502306A1 (en) | 2016-02-15 |
Family
ID=51659357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12015502306A PH12015502306A1 (en) | 2013-04-05 | 2015-10-05 | Matrix metalloproteinases and uses thereof |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20160053250A1 (https=) |
| EP (2) | EP2981276A4 (https=) |
| JP (1) | JP2016520550A (https=) |
| KR (1) | KR20160006694A (https=) |
| CN (1) | CN105246500A (https=) |
| AU (1) | AU2014248002A1 (https=) |
| BR (1) | BR112015025390A2 (https=) |
| CA (1) | CA2908739A1 (https=) |
| CR (1) | CR20150603A (https=) |
| HK (1) | HK1221405A1 (https=) |
| MX (1) | MX2015014053A (https=) |
| PH (1) | PH12015502306A1 (https=) |
| RU (1) | RU2015147878A (https=) |
| SG (1) | SG11201508199QA (https=) |
| WO (1) | WO2014165780A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412916B (zh) * | 2014-09-19 | 2021-04-30 | 达森生物药业有限公司 | 治疗乳腺癌的组合物及其用途 |
| CN105477627B (zh) * | 2014-09-19 | 2021-04-30 | 山东蓝金生物工程有限公司 | 治疗前列腺癌的组合物及其用途 |
| CN105412917B (zh) * | 2014-09-19 | 2021-04-30 | 达森生物药业有限公司 | 治疗实体瘤的抗癌组合物及其用途 |
| CN105477628B (zh) * | 2014-09-19 | 2021-04-30 | 山东蓝金生物工程有限公司 | 抗癌组合物及其用途 |
| JPWO2017038473A1 (ja) * | 2015-08-28 | 2018-06-14 | 天野エンザイム株式会社 | エンドトキシン低減サーモリシン |
| CN105907840A (zh) * | 2016-03-29 | 2016-08-31 | 苏州大学 | 单细胞水平检测mmp酶活性的方法 |
| US10137179B2 (en) * | 2016-05-18 | 2018-11-27 | Hyalo Technologies, LLC | Composition and method of preparation of protease microparticulate slow release preparation |
| CN108451981B (zh) * | 2018-04-21 | 2019-07-23 | 江西汉氏联合干细胞科技有限公司 | 使用皮肤间充质干细胞治疗系统性硬化症 |
| US12569594B2 (en) | 2018-12-20 | 2026-03-10 | The Steadman Clinic And Steadman Philippon Research Institute | Decellularized tendon matrix methods and uses thereof |
| CN114377150B (zh) * | 2021-12-29 | 2023-10-13 | 中山大学南昌研究院 | 一种mmp酶敏感胎盘微环境和肿瘤微环境靶向载体及其制备方法和应用 |
| CN116549325B (zh) * | 2022-01-27 | 2025-07-29 | 南京大学 | 一种组合物、其制备方法、制剂及应用 |
| CN119530138B (zh) * | 2024-12-05 | 2026-01-30 | 中国肉类食品综合研究中心 | 一种用于工业化细胞解离的多酶制剂及其使用方法和应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US5432272A (en) | 1990-10-09 | 1995-07-11 | Benner; Steven A. | Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases |
| US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5770691A (en) * | 1995-06-05 | 1998-06-23 | Regents Of The University Of Minnesota | Discriminatory substrates for MMP hydrolysis |
| ES2317657T3 (es) | 1996-09-19 | 2009-04-16 | The Regents Of The University Of Michigan | Polimeros que contienen polisacaridos tales como alginatos o alginatos modificados. |
| US6531154B1 (en) | 1997-06-10 | 2003-03-11 | Brown University Research Foundation | Modulated release from biocompatible polymers |
| US6248587B1 (en) | 1997-11-26 | 2001-06-19 | University Of Southern Cailfornia | Method for promoting mesenchymal stem and lineage-specific cell proliferation |
| WO1999055396A1 (en) | 1998-04-27 | 1999-11-04 | Surmodics, Inc. | Bioactive agent release coating |
| US6376742B1 (en) | 1999-02-17 | 2002-04-23 | Richard J. Zdrahala | In vivo tissue engineering with biodegradable polymers |
| WO2000051662A1 (en) | 1999-03-04 | 2000-09-08 | Tepha, Inc. | Bioabsorbable, biocompatible polymers for tissue engineering |
| KR100392501B1 (ko) | 2000-06-28 | 2003-07-22 | 동국제약 주식회사 | 다중 에멀젼법에 의한 서방출성 미립구의 제조방법 |
| EP1611233B1 (en) * | 2003-04-08 | 2016-01-06 | Yeda Research And Development Co., Ltd. | Stem cells having increased sensitivity to sdf-1 and methods of generating and using same |
| SE0302559D0 (sv) * | 2003-09-25 | 2003-09-25 | Astrazeneca Ab | Method |
| JP2007508018A (ja) * | 2003-10-08 | 2007-04-05 | べト−ステム インコーポレイテッド | 新規の幹細胞組成物の調製法および使用法、ならびにこの組成物を含有するキット |
| CA2633980A1 (en) * | 2005-12-29 | 2007-07-12 | Anthrogenesis Corporation | Improved composition for collecting and preserving placental stem cells and methods of using the composition |
| WO2007117451A2 (en) * | 2006-03-31 | 2007-10-18 | The Regents Of The University Of Michigan | A pericellular collagenase directs the 3-dimensional development of white adipose tissue |
| MX2010003019A (es) * | 2007-09-19 | 2010-04-30 | Pluristem Ltd | Celulas adherentes de los tejidos adiposo y de placenta y uso de las mismas en la terapia. |
| US8222206B2 (en) * | 2008-03-04 | 2012-07-17 | Taiwan Advance Bio-Pharm Inc. | Method of enhancing the mobilization of hematopoietic stem cells using TAT-HOXB4H |
| JP5572291B2 (ja) * | 2008-04-07 | 2014-08-13 | 独立行政法人国立長寿医療研究センター | 歯髄及び／又は象牙質形成促進のための薬剤及びその利用 |
| US9435811B2 (en) * | 2008-09-30 | 2016-09-06 | Oriental Yeast Co., Ltd | Inducer of chondrocyte proliferation and differentiation |
| CA2794165A1 (en) * | 2010-03-24 | 2011-09-29 | Lifenet Health | Bmp-4 peptides & methods of use |
| EP2608809B1 (en) * | 2010-08-27 | 2019-05-22 | Gilead Biologics, Inc. | Antibodies to matrix metalloproteinase 9 |
-
2014
- 2014-04-04 MX MX2015014053A patent/MX2015014053A/es unknown
- 2014-04-04 RU RU2015147878A patent/RU2015147878A/ru not_active Application Discontinuation
- 2014-04-04 EP EP14779257.6A patent/EP2981276A4/en not_active Withdrawn
- 2014-04-04 EP EP17191200.9A patent/EP3290047A1/en not_active Withdrawn
- 2014-04-04 AU AU2014248002A patent/AU2014248002A1/en not_active Abandoned
- 2014-04-04 KR KR1020157031871A patent/KR20160006694A/ko not_active Withdrawn
- 2014-04-04 SG SG11201508199QA patent/SG11201508199QA/en unknown
- 2014-04-04 CA CA2908739A patent/CA2908739A1/en not_active Abandoned
- 2014-04-04 HK HK16109565.8A patent/HK1221405A1/zh unknown
- 2014-04-04 CN CN201480030453.7A patent/CN105246500A/zh active Pending
- 2014-04-04 BR BR112015025390A patent/BR112015025390A2/pt not_active Application Discontinuation
- 2014-04-04 JP JP2016506654A patent/JP2016520550A/ja active Pending
- 2014-04-04 WO PCT/US2014/033009 patent/WO2014165780A2/en not_active Ceased
- 2014-04-04 US US14/782,118 patent/US20160053250A1/en not_active Abandoned
-
2015
- 2015-10-05 PH PH12015502306A patent/PH12015502306A1/en unknown
- 2015-11-05 CR CR20150603A patent/CR20150603A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1221405A1 (zh) | 2017-06-02 |
| MX2015014053A (es) | 2016-04-07 |
| EP2981276A4 (en) | 2017-03-22 |
| AU2014248002A1 (en) | 2015-11-19 |
| JP2016520550A (ja) | 2016-07-14 |
| US20160053250A1 (en) | 2016-02-25 |
| RU2015147878A (ru) | 2017-05-10 |
| CR20150603A (es) | 2016-04-04 |
| SG11201508199QA (en) | 2015-11-27 |
| CN105246500A (zh) | 2016-01-13 |
| BR112015025390A2 (pt) | 2017-08-29 |
| EP2981276A2 (en) | 2016-02-10 |
| EP3290047A1 (en) | 2018-03-07 |
| WO2014165780A3 (en) | 2014-12-18 |
| CA2908739A1 (en) | 2014-10-09 |
| WO2014165780A2 (en) | 2014-10-09 |
| KR20160006694A (ko) | 2016-01-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12015502306A1 (en) | Matrix metalloproteinases and uses thereof | |
| JP2011517318A5 (https=) | ||
| Zhang et al. | The role of host‐derived dentinal matrix metalloproteinases in reducing dentin bonding of resin adhesives | |
| Shi et al. | Matrix metalloproteinase inhibitors (MMPIs) as attractive therapeutic targets: Recent progress and current challenges | |
| JP2016520550A5 (https=) | ||
| GB9907429D0 (en) | Modulation of C-fibre activity | |
| Isnard et al. | Effect of hyaluronan on MMP expression and activation | |
| Longhi et al. | The effects of host derived metalloproteinases on dentin bond and the role of MMPs inhibitors on dentin matrix degradation | |
| ATE337712T1 (de) | Zusammensetzung zur intestinalen verabreichung | |
| WO2015006469A3 (en) | Method of treating fibroproliferative disorders with human matrix metalloproteinase and a tnf antagonist | |
| CO2022017112A2 (es) | N-cianopirrolidinas con actividad como inhibidores de peptidasa específica de ubiquitina 30 | |
| IL136101A0 (en) | Pharmaceutical compositions containing azelaic acid | |
| Sambandam et al. | Matrix metalloproteinases (mmp) in restorative dentistry and endodontics | |
| MX9603515A (es) | Preparacion farmaceutica que contiene activadores de plasminogeno. | |
| Charles et al. | Role of matrix metalloproteinases (MMPS) in periodontitis and its management | |
| NO20003888L (no) | Anti-enzympreparater omfattende etylendiamindiravsyre | |
| WO2021141368A3 (ko) | 세포 투과성 핵산 복합체를 유효성분으로 함유하는 황반변성의 예방 또는 치료용 조성물 | |
| Hamdi | What is the function of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in pain processes? | |
| Hanemaaijer et al. | Inhibition of matrix metalloproteinases (MMPs) by tetracyclines | |
| GR3036481T3 (en) | Medicament containing delta-aminolevulinic acid | |
| Hoque et al. | Significant correlation between matrix metalloproteinase activity and tumor necrosis factor‐oc in salivary extravasation mucoceles | |
| ATE103178T1 (de) | T-pa pro stabilisierung. | |
| Kang et al. | Roles of matrix metalloproteinase-9 in cancer metastasis | |
| MY114879A (en) | Absorbent product configured to conform to body shape | |
| Roeb | MMP-1 Interstitial collagenase Secreted One of three collagenases that can degrade the interstitial collagens, types I, II, and III MMP-2 |