PE20242224A1 - Anticuerpo anti componente del complemento 1s (c1s) - Google Patents

Anticuerpo anti componente del complemento 1s (c1s)

Info

Publication number
PE20242224A1
PE20242224A1 PE2023002755A PE2023002755A PE20242224A1 PE 20242224 A1 PE20242224 A1 PE 20242224A1 PE 2023002755 A PE2023002755 A PE 2023002755A PE 2023002755 A PE2023002755 A PE 2023002755A PE 20242224 A1 PE20242224 A1 PE 20242224A1
Authority
PE
Peru
Prior art keywords
hvr
antibody
complement component
refers
antigen binding
Prior art date
Application number
PE2023002755A
Other languages
English (en)
Spanish (es)
Inventor
Hikaru Koga
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of PE20242224A1 publication Critical patent/PE20242224A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PE2023002755A 2021-04-15 2022-04-14 Anticuerpo anti componente del complemento 1s (c1s) PE20242224A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021068964 2021-04-15
PCT/JP2022/017780 WO2022220275A1 (ja) 2021-04-15 2022-04-14 抗Ｃ１ｓ抗体

Publications (1)

Publication Number Publication Date
PE20242224A1 true PE20242224A1 (es) 2024-11-19

Family

ID=83640739

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2023002755A PE20242224A1 (es) 2021-04-15 2022-04-14 Anticuerpo anti componente del complemento 1s (c1s)

Country Status (17)

Country Link
US (1) US20240287163A1 (https=)
EP (1) EP4324925A4 (https=)
JP (2) JP7760581B2 (https=)
KR (1) KR20230170017A (https=)
CN (1) CN117120615A (https=)
AR (1) AR125344A1 (https=)
AU (1) AU2022257471B2 (https=)
BR (1) BR112023015422A2 (https=)
CA (1) CA3213912A1 (https=)
CL (1) CL2023003047A1 (https=)
CO (1) CO2023012831A2 (https=)
CR (1) CR20230528A (https=)
IL (1) IL305041A (https=)
MX (1) MX2023010764A (https=)
PE (1) PE20242224A1 (https=)
TW (1) TW202304977A (https=)
WO (1) WO2022220275A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3710589A4 (en) 2017-11-14 2021-11-10 Chugai Seiyaku Kabushiki Kaisha ANTI-C1S ANTIBODIES AND METHOD OF USING
MX2021013441A (es) 2019-05-15 2021-12-10 Chugai Pharmaceutical Co Ltd Molecula de union a antigenos, composicion farmaceutica y metodo.
WO2024143442A1 (ja) 2022-12-27 2024-07-04 中外製薬株式会社 会合が制御されたポリペプチド

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CR20200542A (es) * 2018-04-13 2021-01-18 Chugaiseiyaku Kk Anticuerpos anti-componente de complemento y métodos de uso
JP6968025B2 (ja) 2018-04-27 2021-11-17 日立Astemo株式会社 車載用電子機器筐体
MX2021013441A (es) * 2019-05-15 2021-12-10 Chugai Pharmaceutical Co Ltd Molecula de union a antigenos, composicion farmaceutica y metodo.
TWI856193B (zh) * 2019-10-16 2024-09-21 日商中外製藥股份有限公司 抗體、醫藥組成物及方法

Also Published As

Publication number Publication date
US20240287163A1 (en) 2024-08-29
CO2023012831A2 (es) 2023-10-19
JP2026012762A (ja) 2026-01-27
CL2023003047A1 (es) 2024-03-15
MX2023010764A (es) 2023-09-22
AU2022257471B2 (en) 2026-01-22
IL305041A (en) 2023-10-01
AU2022257471A1 (en) 2023-08-24
CR20230528A (es) 2023-12-05
AU2022257471A9 (en) 2024-07-18
CN117120615A (zh) 2023-11-24
EP4324925A1 (en) 2024-02-21
BR112023015422A2 (pt) 2023-11-07
JPWO2022220275A1 (https=) 2022-10-20
WO2022220275A1 (ja) 2022-10-20
CA3213912A1 (en) 2022-10-20
EP4324925A4 (en) 2025-04-09
TW202304977A (zh) 2023-02-01
AR125344A1 (es) 2023-07-05
KR20230170017A (ko) 2023-12-18
JP7760581B2 (ja) 2025-10-27

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