PE20150212A1 - Anticuerpos anti-trka con propiedades inhibitorias mejoradas y sus derivados - Google Patents

Anticuerpos anti-trka con propiedades inhibitorias mejoradas y sus derivados

Info

Publication number
PE20150212A1
PE20150212A1 PE2014002388A PE2014002388A PE20150212A1 PE 20150212 A1 PE20150212 A1 PE 20150212A1 PE 2014002388 A PE2014002388 A PE 2014002388A PE 2014002388 A PE2014002388 A PE 2014002388A PE 20150212 A1 PE20150212 A1 PE 20150212A1
Authority
PE
Peru
Prior art keywords
derivatives
pain
inhibitory properties
seq
refers
Prior art date
Application number
PE2014002388A
Other languages
English (en)
Spanish (es)
Inventor
Stanislas Blein
Romain Ollier
Darko Skegro
Original Assignee
Glenmark Pharmaceuticals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48906463&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20150212(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glenmark Pharmaceuticals Sa filed Critical Glenmark Pharmaceuticals Sa
Publication of PE20150212A1 publication Critical patent/PE20150212A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

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  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
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  • Psychiatry (AREA)
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PE2014002388A 2012-06-08 2013-06-07 Anticuerpos anti-trka con propiedades inhibitorias mejoradas y sus derivados PE20150212A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261657184P 2012-06-08 2012-06-08

Publications (1)

Publication Number Publication Date
PE20150212A1 true PE20150212A1 (es) 2015-02-27

Family

ID=48906463

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2014002388A PE20150212A1 (es) 2012-06-08 2013-06-07 Anticuerpos anti-trka con propiedades inhibitorias mejoradas y sus derivados

Country Status (20)

Country Link
US (2) US20130344064A1 (enExample)
EP (1) EP2859019B1 (enExample)
JP (1) JP2015520182A (enExample)
KR (1) KR20150023679A (enExample)
CN (1) CN104520330A (enExample)
AP (1) AP2014008145A0 (enExample)
AU (1) AU2013273115B2 (enExample)
CA (1) CA2875703A1 (enExample)
CL (1) CL2014003339A1 (enExample)
CO (1) CO7240431A2 (enExample)
EA (1) EA201492163A1 (enExample)
ES (1) ES2666126T3 (enExample)
IL (1) IL235994A0 (enExample)
IN (1) IN2014MN02656A (enExample)
MX (1) MX362394B (enExample)
PE (1) PE20150212A1 (enExample)
PH (1) PH12014502722A1 (enExample)
SG (1) SG11201408037SA (enExample)
UA (1) UA113879C2 (enExample)
WO (1) WO2013183032A2 (enExample)

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US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
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MA41097A (fr) * 2014-12-05 2017-10-10 Glenmark Pharmaceuticals Sa Anticorps anti-trka à propriétés inhibitrices améliorées et dérivés desdits anticorps destinés à être utilisés pour traiter les douleurs osseuses
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CN110177876B (zh) * 2017-01-10 2023-03-31 国立大学法人山口大学 抗gpc3抗体
JP7183268B2 (ja) 2017-11-20 2022-12-05 ジャスト－エヴォテック バイオロジックス、インコーポレイテッド 等張化剤としてリジン塩を含有するアフリベルセプト製剤及びその使用
AR114110A1 (es) * 2018-02-28 2020-07-22 Lilly Co Eli Anticuerpo anti-trka
EP3976657A4 (en) * 2019-05-30 2023-07-05 Sunshine Lake Pharma Co., Ltd. ANTI-TRKA ANTIBODIES AND USES THEREOF
CN116003590A (zh) * 2020-08-06 2023-04-25 熙源安健医药（上海）有限公司 抗ngf抗体及其抗原结合片段、其制备方法和应用
JP2023549300A (ja) * 2020-11-20 2023-11-24 サンシャイン・レイク・ファーマ・カンパニー・リミテッド ヒト化抗ＴｒｋＡ抗体及びその使用
CN112961244B (zh) * 2021-02-28 2023-08-29 熙源安健医药（上海）有限公司 抗TrkA抗体或其抗原结合片段、其制备方法和应用
KR20260013489A (ko) * 2023-05-23 2026-01-28 4비 테크놀로지스 (상하이) 컴퍼니 리미티드 TrkA 항체 및 이의 용도

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IL235994A0 (en) 2015-01-29
CO7240431A2 (es) 2015-04-17
MX2014015043A (es) 2015-02-20
IN2014MN02656A (enExample) 2015-08-21
CN104520330A (zh) 2015-04-15
JP2015520182A (ja) 2015-07-16
US20130344064A1 (en) 2013-12-26
AU2013273115A2 (en) 2015-01-22
CA2875703A1 (en) 2013-12-12
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AP2014008145A0 (en) 2014-12-31
EA201492163A1 (ru) 2015-08-31
MX362394B (es) 2019-01-15
ES2666126T3 (es) 2018-05-03
EP2859019A2 (en) 2015-04-15
UA113879C2 (xx) 2017-03-27
KR20150023679A (ko) 2015-03-05
WO2013183032A3 (en) 2014-02-20
AU2013273115A1 (en) 2015-01-22
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