PE20141351A1 - Triazolopiridinas - Google Patents
TriazolopiridinasInfo
- Publication number
- PE20141351A1 PE20141351A1 PE2013002378A PE2013002378A PE20141351A1 PE 20141351 A1 PE20141351 A1 PE 20141351A1 PE 2013002378 A PE2013002378 A PE 2013002378A PE 2013002378 A PE2013002378 A PE 2013002378A PE 20141351 A1 PE20141351 A1 PE 20141351A1
- Authority
- PE
- Peru
- Prior art keywords
- amino
- halo
- phenyl
- alkyl
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11163342 | 2011-04-21 | ||
EP11167872 | 2011-05-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20141351A1 true PE20141351A1 (es) | 2014-11-01 |
Family
ID=46124297
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2013002378A PE20141351A1 (es) | 2011-04-21 | 2012-04-16 | Triazolopiridinas |
Country Status (39)
Country | Link |
---|---|
US (1) | US20140120087A1 (sl) |
EP (1) | EP2699575B1 (sl) |
JP (1) | JP5989091B2 (sl) |
KR (1) | KR20140025470A (sl) |
CN (1) | CN103608350B (sl) |
AP (1) | AP3491A (sl) |
AR (1) | AR086191A1 (sl) |
AU (1) | AU2012244859B2 (sl) |
CA (1) | CA2833657A1 (sl) |
CL (1) | CL2013003044A1 (sl) |
CO (1) | CO6801751A2 (sl) |
CR (1) | CR20130539A (sl) |
CY (1) | CY1116439T1 (sl) |
DK (1) | DK2699575T3 (sl) |
DO (1) | DOP2013000244A (sl) |
EA (1) | EA023766B1 (sl) |
EC (1) | ECSP13013011A (sl) |
ES (1) | ES2539265T3 (sl) |
GT (1) | GT201300254A (sl) |
HK (1) | HK1190398A1 (sl) |
HR (1) | HRP20150517T1 (sl) |
HU (1) | HUE025496T2 (sl) |
IL (1) | IL228704A0 (sl) |
JO (1) | JO3040B1 (sl) |
MA (1) | MA35049B1 (sl) |
ME (1) | ME02143B (sl) |
MX (1) | MX348783B (sl) |
MY (1) | MY164939A (sl) |
PE (1) | PE20141351A1 (sl) |
PL (1) | PL2699575T3 (sl) |
PT (1) | PT2699575E (sl) |
RS (1) | RS54044B1 (sl) |
SA (1) | SA112330466B1 (sl) |
SG (1) | SG194003A1 (sl) |
SI (1) | SI2699575T1 (sl) |
TW (1) | TWI558703B (sl) |
UY (1) | UY34034A (sl) |
WO (1) | WO2012143329A1 (sl) |
ZA (1) | ZA201308707B (sl) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2699558T (pt) | 2011-04-21 | 2016-12-29 | Gilead Sciences Inc | Compostos de benzotiazole e a sua utilização farmacêutica |
UA112096C2 (uk) * | 2011-12-12 | 2016-07-25 | Байєр Інтеллектуал Проперті Гмбх | Заміщені триазолопіридини та їх застосування як інгібіторів ttk |
WO2013103724A1 (en) | 2012-01-04 | 2013-07-11 | Gilead Sciences, Inc. | 2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids |
US9284323B2 (en) | 2012-01-04 | 2016-03-15 | Gilead Sciences, Inc. | Naphthalene acetic acid derivatives against HIV infection |
ES2605946T3 (es) | 2012-03-14 | 2017-03-17 | Bayer Intellectual Property Gmbh | Imidazopiridazinas sustituidas |
AU2013289381A1 (en) * | 2012-07-10 | 2015-01-22 | Bayer Pharma Aktiengesellschaft | Method for preparing substituted triazolopyridines |
WO2014020043A1 (en) | 2012-08-02 | 2014-02-06 | Bayer Pharma Aktiengesellschaft | Combinations for the treatment of cancer |
WO2014020041A1 (en) | 2012-08-02 | 2014-02-06 | Bayer Pharma Aktiengesellschaft | Combinations for the treatment of cancer |
US9670202B2 (en) * | 2013-06-07 | 2017-06-06 | Bayer Pharma Aktiengesellschaft | Substituted triazolopyridines |
US20160264568A1 (en) * | 2013-06-07 | 2016-09-15 | Bayer Pharma Aktiengesellschaft | Substituted triazolopyridines having activity as mps-1 inhibitors |
WO2014198594A1 (en) * | 2013-06-10 | 2014-12-18 | Bayer Pharma Aktiengesellschaft | Novel compounds for the treatment of cancer |
PT3008062T (pt) | 2013-06-11 | 2017-06-07 | Bayer Pharma AG | Derivados de profármaco de triazolopiridinas substituídas |
MA38656A1 (fr) * | 2013-06-11 | 2018-05-31 | Bayer Pharma AG | Combinaisons pour le traitement du cancer comprenant un inhibiteur de la kinase mps-1 et un inhibiteur de la mitose |
EP2860177A3 (en) | 2013-09-20 | 2015-06-10 | Bayer Intellectual Property GmbH | Synthesis of functionalized arenes |
EP3283642B1 (en) | 2015-04-17 | 2023-10-11 | Netherlands Translational Research Center Holding B.V. | Prognostic biomarkers for ttk inhibitor chemotherapy |
WO2018166493A1 (zh) * | 2017-03-16 | 2018-09-20 | 江苏恒瑞医药股份有限公司 | 杂芳基并[4,3-c]嘧啶-5-胺类衍生物、其制备方法及其在医药上的应用 |
AU2020257301A1 (en) | 2019-04-18 | 2021-11-11 | The Johns Hopkins University | Substituted 2-amino-pyrazolyl-(1,2,4)triazolo(1,5a) pyridine derivatives and use thereof |
US11529350B2 (en) | 2019-07-03 | 2022-12-20 | Sumitomo Pharma Oncology, Inc. | Tyrosine kinase non-receptor 1 (TNK1) inhibitors and uses thereof |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
US5011472A (en) | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
RU2007109778A (ru) | 2004-08-17 | 2008-09-27 | Галдерма Ресерч Энд Девелопмент, С.Н.С. (Fr) | Новые биароматические соединения, которые активируют рецепторы типа ppar, и их применение в косметических и фармацевтических композициях |
CN103641829A (zh) * | 2006-08-30 | 2014-03-19 | 塞尔佐姆有限公司 | 作为激酶抑制剂的三唑衍生物 |
KR20100049073A (ko) | 2007-07-18 | 2010-05-11 | 노파르티스 아게 | 비시클릭 헤테로아릴 화합물 및 키나제 억제제로서의 그의 용도 |
BRPI0815709A2 (pt) | 2007-08-23 | 2017-06-13 | Astrazeneca Ab | composro, composição farmacêutica, e, uso de um composto. |
JP2010536917A (ja) * | 2007-08-31 | 2010-12-02 | メルク セローノ ソシエテ アノニム | トリアゾロピリジン化合物と、ask阻害剤としてのその化合物の利用法 |
GB0719803D0 (en) * | 2007-10-10 | 2007-11-21 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
BRPI0819606A2 (pt) * | 2007-11-27 | 2017-05-09 | Cellzome Ltd | amino triazóis como inobidores de pi3k |
SG173610A1 (en) | 2009-02-13 | 2011-09-29 | Fovea Pharmaceuticals Sa | [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors |
CN102413831B (zh) | 2009-04-29 | 2014-06-04 | 拜耳知识产权有限责任公司 | 取代的咪唑并喹喔啉 |
CA2772790C (en) | 2009-09-04 | 2017-06-27 | Benjamin Bader | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors |
EP2343297A1 (en) * | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Triazolopyridines |
UY33452A (es) * | 2010-06-16 | 2012-01-31 | Bayer Schering Pharma Ag | Triazolopiridinas sustituidas |
-
2012
- 2012-04-16 CN CN201280030682.XA patent/CN103608350B/zh not_active Expired - Fee Related
- 2012-04-16 US US14/113,017 patent/US20140120087A1/en not_active Abandoned
- 2012-04-16 ME MEP-2015-80A patent/ME02143B/me unknown
- 2012-04-16 MY MYPI2013701964A patent/MY164939A/en unknown
- 2012-04-16 AP AP2013007182A patent/AP3491A/xx active
- 2012-04-16 SI SI201230220T patent/SI2699575T1/sl unknown
- 2012-04-16 AU AU2012244859A patent/AU2012244859B2/en not_active Ceased
- 2012-04-16 CA CA2833657A patent/CA2833657A1/en not_active Abandoned
- 2012-04-16 MX MX2013012289A patent/MX348783B/es active IP Right Grant
- 2012-04-16 EA EA201301181A patent/EA023766B1/ru not_active IP Right Cessation
- 2012-04-16 PL PL12721779T patent/PL2699575T3/pl unknown
- 2012-04-16 DK DK12721779.2T patent/DK2699575T3/da active
- 2012-04-16 MA MA36344A patent/MA35049B1/fr unknown
- 2012-04-16 RS RS20150345A patent/RS54044B1/en unknown
- 2012-04-16 HU HUE12721779A patent/HUE025496T2/en unknown
- 2012-04-16 PE PE2013002378A patent/PE20141351A1/es not_active Application Discontinuation
- 2012-04-16 KR KR1020137030546A patent/KR20140025470A/ko not_active Application Discontinuation
- 2012-04-16 WO PCT/EP2012/056914 patent/WO2012143329A1/en active Application Filing
- 2012-04-16 EP EP12721779.2A patent/EP2699575B1/en active Active
- 2012-04-16 JP JP2014505584A patent/JP5989091B2/ja not_active Expired - Fee Related
- 2012-04-16 ES ES12721779.2T patent/ES2539265T3/es active Active
- 2012-04-16 PT PT127217792T patent/PT2699575E/pt unknown
- 2012-04-16 SG SG2013073044A patent/SG194003A1/en unknown
- 2012-04-18 SA SA112330466A patent/SA112330466B1/ar unknown
- 2012-04-18 JO JOP/2012/0093A patent/JO3040B1/ar active
- 2012-04-20 AR ARP120101355A patent/AR086191A1/es active Pending
- 2012-04-20 UY UY0001034034A patent/UY34034A/es not_active Application Discontinuation
- 2012-04-20 TW TW101114259A patent/TWI558703B/zh not_active IP Right Cessation
-
2013
- 2013-10-03 IL IL228704A patent/IL228704A0/en unknown
- 2013-10-18 GT GT201300254A patent/GT201300254A/es unknown
- 2013-10-21 CR CR20130539A patent/CR20130539A/es unknown
- 2013-10-21 CL CL2013003044A patent/CL2013003044A1/es unknown
- 2013-10-21 CO CO13248763A patent/CO6801751A2/es active IP Right Grant
- 2013-10-21 DO DO2013000244A patent/DOP2013000244A/es unknown
- 2013-11-05 EC ECSP13013011 patent/ECSP13013011A/es unknown
- 2013-11-20 ZA ZA2013/08707A patent/ZA201308707B/en unknown
-
2014
- 2014-04-15 HK HK14103581.3A patent/HK1190398A1/zh not_active IP Right Cessation
-
2015
- 2015-05-14 HR HRP20150517TT patent/HRP20150517T1/hr unknown
- 2015-06-12 CY CY20151100512T patent/CY1116439T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20141351A1 (es) | Triazolopiridinas | |
PE20130611A1 (es) | Triazolopiridinas sustituidas | |
PE20141404A1 (es) | Derivados de tieno[3,2-d]pirimidina que tienen actividad inhibidora por las quinasas de las proteinas | |
PE20211411A1 (es) | Compuestos de anillo fusionado | |
PE20190336A1 (es) | Nuevos derivados de amonio, un proceso para su preparacion y composiciones farmaceuticas que los contienen | |
PE20171341A1 (es) | Compuestos de pirazina para el tratamiento de enfermedades infecciosas | |
NZ600229A (en) | Triazolopyridines | |
PE20090370A1 (es) | Derivados de heterociclo fusionado como inhibidores de quinasa | |
PE20141405A1 (es) | Nuevos derivados de indolizina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen | |
PE20191245A1 (es) | Compuestos de tiazolcarboxamidas y piridinacarboxamida utiles como inhibidores de quinasa pim | |
PE20160240A1 (es) | Nuevos derivados de indolizina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen | |
CY1124680T1 (el) | Παραγωγα 8-[6-[3-(αμινο)προποξυ]-3-πυριδυλο]-1-ισοπροπυλο-ιμιδαζο[4,5-c]κινολιν-2-ονης ως εκλεκτiκοι ρυθμιστες κινασης μεταλλαγμενης αταξιας τελαγγειεκτασιας (atm) για τη θεραπευτικη αγωγη του καρκινου | |
PE20121352A1 (es) | Derivados de heteroarilo que contienen n como inhibidores de cinasa jak3 | |
PE20110545A1 (es) | Compuestos de triazolopiridina como inhibidores de jak | |
PE20170663A1 (es) | Compuestos de 5- cloro- 2- difluorometoxifenil pirazolopirimidina, composiciones y metodos de uso de los mismos | |
EA201691428A1 (ru) | Бициклические гетероциклические производные в качестве ингибиторов irak4 | |
DOP2012000298A (es) | Compuestos inductores de la apoptosis derivados de sulfonil carbamoil-fenoxi pirrolopiridina, útiles en el tratamiento del cancer y de enfermedades inmunes y autoinmunes | |
AR097024A1 (es) | Derivados sustituidos de quinazolin-4-ona | |
PE20141050A1 (es) | Inhibidores de quinasa relacionados con pirrolo (2,3-d) pirimidina tropomiosina | |
PE20141973A1 (es) | Compuestos de heterociclilo como inhibidores de mek | |
PE20121815A1 (es) | Compuestos de pirrolo-pirimidina como inhibidores de cdk4/6 | |
AR092876A1 (es) | Inhibidores no nucleosidos de la transcriptasa inversa | |
AR074052A1 (es) | Compuestos pirazolo{1,5-a}pirimidina sustituida como inhibidores de trk cinasa | |
NI201400023A (es) | Derivados de pirrolopirimidina y purina | |
AR077468A1 (es) | Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |