PE20120075A1 - Composiciones farmaceuticas para la liberacion sostenida de fenilefrina - Google Patents

Composiciones farmaceuticas para la liberacion sostenida de fenilefrina

Info

Publication number
PE20120075A1
PE20120075A1 PE2011001106A PE2011001106A PE20120075A1 PE 20120075 A1 PE20120075 A1 PE 20120075A1 PE 2011001106 A PE2011001106 A PE 2011001106A PE 2011001106 A PE2011001106 A PE 2011001106A PE 20120075 A1 PE20120075 A1 PE 20120075A1
Authority
PE
Peru
Prior art keywords
weight
total composition
phenylephrine
composition
histamine
Prior art date
Application number
PE2011001106A
Other languages
English (en)
Inventor
Ramos Jose De Jesus Mateo Villacampa
Sergio R Ulloa
Vargas Luis Javier Juarez
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38565616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20120075(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of PE20120075A1 publication Critical patent/PE20120075A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: (A) UN PRINCIPIO ACTIVO TAL COMO FENILEFRINA EN UNA CANTIDA DE 5-30% EN PESO DE COMPOSICION TOTAL COMPRENDIDA EN UNA MATRIZ ADEMAS DE UNO O MAS PRINCIPIOS ACTIVOS SELECCIONADOS ENTRE ANTIHISTAMINICO, ANALGESICO, ANTIPIRETICO Y ANTIMFLAMATORIO NO ESTEROIDE DE LIBERACION INMEDIATA; (B) UNA MATRIZ O RED POLIMERICA HIDROFILICA QUE COMPRENDE UNA MEZCLA DE HIDROXIPROPILMETILCELULOSA EN LA CANTIDAD DE 20 A 70 % EN PESO DE LA COMPOSICION TOTAL Y SAL DE CARBOXIMETIL CELULOSA SODICA PRESENTE EN 5-50% EN PESO DE LA COMPOSICION TOTAL; (C) UN ANTIADHERENTE TAL COMO POLIVINILPIRROLIDONA CON UNA DISTRIBUCION DE TAMANO DE PARTICULA DE 90% DE PARTICULAS INFERIORES A 20 MICRONES EN LA PROPORCION DE 0.1-10% EN PESO DE LA COMPOSICION TOTAL ADEMAS DE OTROS EXCIPIENTES TALES COMO LUBRICANTES Y DESLIZANTES O MEZCLAS DE LOS MISMOS; (D) UN RECUBRIMIENTO DE PELICULA HIDROFILICO QUE COMPRENDE LORATADINA O DESLORATADINA. LA COMPOSICION ES DE LIBERACION PROLONGADA Y SE PUEDE ADMINISTRAR EN FORMA ORAL SIENDO UTIL EN EL TRATAMIENTO DE RESFRIO, GRIPE O ALERGIA
PE2011001106A 2006-06-01 2007-06-01 Composiciones farmaceuticas para la liberacion sostenida de fenilefrina PE20120075A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81001906P 2006-06-01 2006-06-01

Publications (1)

Publication Number Publication Date
PE20120075A1 true PE20120075A1 (es) 2012-02-20

Family

ID=38565616

Family Applications (3)

Application Number Title Priority Date Filing Date
PE2015000135A PE20150773A1 (es) 2006-06-01 2007-06-01 Composiciones farmaceuticas para la liberacion sostenida de fenilefrina
PE2007000686A PE20080330A1 (es) 2006-06-01 2007-06-01 Composiciones farmaceuticas para la liberacion sostenida de fenilefrina
PE2011001106A PE20120075A1 (es) 2006-06-01 2007-06-01 Composiciones farmaceuticas para la liberacion sostenida de fenilefrina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PE2015000135A PE20150773A1 (es) 2006-06-01 2007-06-01 Composiciones farmaceuticas para la liberacion sostenida de fenilefrina
PE2007000686A PE20080330A1 (es) 2006-06-01 2007-06-01 Composiciones farmaceuticas para la liberacion sostenida de fenilefrina

Country Status (17)

Country Link
US (1) US20070281020A1 (es)
EP (1) EP2029114B1 (es)
JP (1) JP5121824B2 (es)
KR (1) KR101464771B1 (es)
CN (2) CN104606163A (es)
AR (1) AR061166A1 (es)
AU (1) AU2007254826B2 (es)
BR (1) BRPI0711871A2 (es)
CA (1) CA2653955C (es)
MX (1) MX2008015358A (es)
NO (1) NO20085414L (es)
PE (3) PE20150773A1 (es)
RU (1) RU2450803C2 (es)
SG (1) SG172660A1 (es)
TW (1) TWI405567B (es)
WO (1) WO2007143163A2 (es)
ZA (1) ZA200810178B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8343524B2 (en) 2008-07-31 2013-01-01 Clarke Mosquito Control Products, Inc. Extended release tablet and method for making and using same
TWI394594B (zh) * 2009-03-06 2013-05-01 China Chemical & Pharmaceutical Co Ltd 錠劑藥學組成物及其製造方法
US20110104272A1 (en) * 2009-11-05 2011-05-05 Depomed, Inc. Gastric retentive extended-release dosage forms comprising combinations of acetaminophen and phenylephrine
US20110104273A1 (en) * 2009-11-05 2011-05-05 Depomed, Inc. Gastric retentive pharmaceutical compositions for immediate and extended release of phenylephrine
EP2552419A2 (en) * 2010-03-31 2013-02-06 Wockhardt Limited Modified release dosage form comprising desvenlafaxine or salts thereof
US20140271891A1 (en) 2013-03-15 2014-09-18 Mcneil-Ppc, Inc. Phenylephrine resinate particles and use thereof in pharmaceutical formulations
US20140271893A1 (en) 2013-03-15 2014-09-18 Mcneil-Ppc, Inc. Coated phenylephrine particles and use thereof in pharmaceutical formulations
EP3193845A1 (en) 2014-09-19 2017-07-26 The Procter and Gamble Company Pulsed release phenylephrine dosage forms
MA41152A (fr) 2014-12-12 2017-10-17 Johnson & Johnson Consumer Inc Procédé de fabrication de particules de résinate de phényléphrine ; particules de résinate de phényléphrine et utilisation des particules de résinate de phényléphrine dans des formulations pharmaceutiques
US10278930B2 (en) 2017-03-16 2019-05-07 The Procter & Gamble Company Method for relieving sinus congestion

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492397A (en) * 1967-04-07 1970-01-27 Warner Lambert Pharmaceutical Sustained release dosage in the pellet form and process thereof
US3558768A (en) * 1969-12-19 1971-01-26 Sterling Drug Inc Sustained release pharmaceutical compositions
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4282233B1 (en) * 1980-06-19 2000-09-05 Schering Corp Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
AU570306B2 (en) * 1984-02-15 1988-03-10 Schering Corporation 8-chloro-6, 11-dihydro-11-(4-piperidylidene)-5h-benzo (5,6) cyclohepta (1,2-b) pyridine and its salts.
US5025019A (en) * 1984-04-09 1991-06-18 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4623664A (en) * 1985-10-31 1986-11-18 University Of Iowa Research Foundation Oil suspended phenylephrine
US4764378A (en) * 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
US4816264A (en) * 1986-06-06 1989-03-28 Warner-Lambert Company Sustained release formulations
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
US5085865A (en) * 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
FR2655266B1 (fr) * 1989-12-05 1992-04-03 Smith Kline French Lab Compositions pharmaceutiques a base de cimetidine.
IT1246188B (it) * 1990-07-27 1994-11-16 Resa Farma Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute.
ES2067957T3 (es) * 1990-08-07 1995-04-01 Pfizer Uso de membranas polimerizadas interfacialmente en dispositivos de liberacion.
US5518730A (en) * 1992-06-03 1996-05-21 Fuisz Technologies Ltd. Biodegradable controlled release flash flow melt-spun delivery system
US5314697A (en) * 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
US6160020A (en) * 1996-12-20 2000-12-12 Mcneill-Ppc, Inc. Alkali metal and alkaline-earth metal salts of acetaminophen
MX9701946A (es) * 1997-03-14 1998-04-30 Arturo Jimenez Bayardo Solucion oftalmica transportadora.
DK1021204T3 (da) * 1997-09-26 2006-05-08 Noven Pharma Bioadhæsive præparater og fremgangsmåder til topisk administration af aktive midler
ZA9810765B (en) * 1998-05-28 1999-08-06 Ranbaxy Lab Ltd Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.
US6602521B1 (en) * 1998-09-29 2003-08-05 Impax Pharmaceuticals, Inc. Multiplex drug delivery system suitable for oral administration
US6521254B2 (en) * 1998-12-07 2003-02-18 J-Med Pharmaceuticals, Inc. Single-dose antihistamine/decongestant formulations for treating rhinitis
US6267986B1 (en) * 1999-09-24 2001-07-31 Ranbaxy Laboratories Limited Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine
US6114346A (en) * 1999-10-22 2000-09-05 Schering Corporation Treating sleep disorders using desloratadine
AU2277101A (en) * 1999-12-20 2001-07-03 Schering Corporation Stable extended release oral dosage composition
AU2276801A (en) * 1999-12-20 2001-07-03 Schering Corporation Extended release oral dosage composition
US6955821B2 (en) * 2000-04-28 2005-10-18 Adams Laboratories, Inc. Sustained release formulations of guaifenesin and additional drug ingredients
WO2001089476A1 (en) * 2000-05-19 2001-11-29 Npd Llc Chewing gums, lozenges, candies, tablets, liquids, and sprays for efficient delivery of medications and dietary supplements
AU2002220248A1 (en) * 2000-11-06 2002-05-15 Andrx Pharmaceuticals, Inc. Once a day antihistamine and decongestant formulation
US20030236275A1 (en) * 2002-06-20 2003-12-25 Schering Corporation Treatment methods of nasal congestion and nasal obstruction
US7163696B2 (en) * 2001-10-11 2007-01-16 Pfizer Inc. Pharmaceutical formulations
US20030083354A1 (en) * 2001-10-26 2003-05-01 Pediamed Pharmaceuticals, Inc. Phenylephrine tannate and pyrilamine tannate salts in pharmaceutical compositions
US6827946B2 (en) * 2001-12-05 2004-12-07 Collegium Pharmaceutical, Inc. Compositions containing both sedative and non-sedative antihistamines
US20030114535A1 (en) * 2001-12-14 2003-06-19 Jame Fine Chemicals, Inc. Dextrochlorpheniramine tannate
KR100540035B1 (ko) * 2002-02-01 2005-12-29 주식회사 태평양 다단계 경구 약물 방출 제어 시스템
US20030203027A1 (en) * 2002-04-26 2003-10-30 Ethicon, Inc. Coating technique for deposition of drug substance on a substrate
US20040253311A1 (en) * 2002-12-18 2004-12-16 Roger Berlin Multi-layer tablet comprising non-steroidal anti-inflammatory drugs, decongestants and non-sedating antihist amines
US6979689B2 (en) * 2002-12-20 2005-12-27 Pediamed Pharmaceuticals, Inc. Compositions and methods for treating upper respiratory congestion
US20040214215A1 (en) * 2003-03-07 2004-10-28 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
US20050152967A1 (en) * 2003-03-28 2005-07-14 Pfab, Lp Dynamic variable release
US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
US20050095288A1 (en) * 2003-11-03 2005-05-05 Andrx Labs, Llc Decongestant and expectorant tablets
US9492541B2 (en) * 2004-09-14 2016-11-15 Sovereign Pharmaceuticals, Llc Phenylepherine containing dosage form
US20050266032A1 (en) * 2003-12-17 2005-12-01 Sovereign Pharmaceuticals, Ltd. Dosage form containing multiple drugs
US20050220877A1 (en) * 2004-03-31 2005-10-06 Patel Ashish A Bilayer tablet comprising an antihistamine and a decongestant
CA2590834A1 (en) * 2004-12-13 2006-06-22 Mcneil-Ppc, Inc. Compositons and methods for stabilizing active pharmaceutical ingredients
US8940796B2 (en) * 2006-02-21 2015-01-27 Wyeth Llc Phenylephrine liquid formulations
US20080014274A1 (en) * 2006-07-14 2008-01-17 Wyeth Enhanced stability phenylephrine liquid compositions
US9005652B2 (en) * 2006-07-25 2015-04-14 Wyeth Chewable tablet containing phenylephrine
US7378082B1 (en) * 2007-11-05 2008-05-27 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects

Also Published As

Publication number Publication date
EP2029114A2 (en) 2009-03-04
MX2008015358A (es) 2009-03-06
KR20090015990A (ko) 2009-02-12
TWI405567B (zh) 2013-08-21
PE20150773A1 (es) 2015-05-21
RU2008151946A (ru) 2010-07-20
WO2007143163A3 (en) 2008-07-24
JP5121824B2 (ja) 2013-01-16
ZA200810178B (en) 2009-12-30
EP2029114B1 (en) 2014-09-24
NO20085414L (no) 2008-12-30
BRPI0711871A2 (pt) 2011-12-06
RU2450803C2 (ru) 2012-05-20
CA2653955A1 (en) 2007-12-13
KR101464771B1 (ko) 2014-11-26
WO2007143163A2 (en) 2007-12-13
CN104606163A (zh) 2015-05-13
CN101505735A (zh) 2009-08-12
PE20080330A1 (es) 2008-04-25
CA2653955C (en) 2015-10-27
AU2007254826A1 (en) 2007-12-13
JP2009538921A (ja) 2009-11-12
SG172660A1 (en) 2011-07-28
TW200804235A (en) 2008-01-16
US20070281020A1 (en) 2007-12-06
AU2007254826B2 (en) 2013-10-24
AR061166A1 (es) 2008-08-06

Similar Documents

Publication Publication Date Title
PE20120075A1 (es) Composiciones farmaceuticas para la liberacion sostenida de fenilefrina
HRP20200138T1 (hr) Kombinirana formulacija dva antivirusna spoja
RS54152B1 (en) PHARMACEUTICAL DOSAGE FORMS WITH CONTROLLED RELEASE
HRP20192026T1 (hr) Formulacija tableta od neratinib maleata
HRP20120264T1 (hr) Farmaceutski sastavi neuroaktivnog steroida i njihove uporabe
HRP20171739T1 (hr) Postupci i kompozicije za liječenje simptoma povezanih s posttraumatskim stresnim poremećajem korištenjem ciklobenzaprina
AR058604A1 (es) Comprimido multicapa con combinacion de triple liberacion
WO2011079239A3 (en) Combination tablet with chewable outer layer
HRP20151095T1 (hr) Farmaceutski pripravci koji sadrže rifaksimin, postupci za njihovu proizvodnju i njihova primjena u lijeäśenju vaginalnih infekcija
PE20110573A1 (es) Sistema de administracion de drogas que contiene progestina
RS52463B (en) PHARMACEUTICAL DOSAGE FORMS ABUSE-RESISTANT CONTAINING OPIOID ANALGETIC
HRP20220902T3 (hr) Pripravci i njihova upotreba u liječenju multiple skleroze
EA200700049A1 (ru) Препаративные формы оральных лекарственных форм мемантина с модифицированным высвобождением
BRPI0516718A (pt) forma de dosagem de ibuprofeno de liberação modificada
JP2013542246A5 (es)
CU24619B1 (es) Letermovir amorfo y formulaciones farmacéuticas sólidas del mismo para administración por via oral
JP2010222367A5 (es)
RS53554B1 (en) PHARMACEUTICAL COMPOSITIONS CONTAINING 2-OXO-1-PYROLIDINE DERIVATIVES
AR070025A1 (es) Uso de derivados de 1-amino-alquilciclohexano para el tratamiento del tinnitus coclear y composicion farmaceutica
BR112013006597A2 (pt) tablete para desintegração oral em múltiplas camadas, e a fabricação do mesmo
BR112017008993A2 (pt) métodos e composições especificamente para o tratamento de transtorno de déficit de atenção
MX2008002512A (es) Composiciones de farmaco que contienen matrices de hipromelosa con liberacion controlada.
CO6150126A2 (es) Formulaciones de comprimidos de liberacion inmediata de un antagonista del receptor de trombina
MY169068A (en) Orally available pharmaceutical formulation suitable for improved management of movement disorders
FR2931359B1 (fr) Utilisation d'une matrice pour administration orale de magnesium a liberation prolongee, et composition contenant cette matrice

Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed