PE20051112A1 - Derivados de naftiridina sustituidos como inhibidores del factor inhibidor de la migracion de macrofagos - Google Patents

Derivados de naftiridina sustituidos como inhibidores del factor inhibidor de la migracion de macrofagos

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Publication number
PE20051112A1
PE20051112A1 PE2004000808A PE2004000808A PE20051112A1 PE 20051112 A1 PE20051112 A1 PE 20051112A1 PE 2004000808 A PE2004000808 A PE 2004000808A PE 2004000808 A PE2004000808 A PE 2004000808A PE 20051112 A1 PE20051112 A1 PE 20051112A1
Authority
PE
Peru
Prior art keywords
inhibitors
alkyl
naphthyridine derivatives
inhibitor factor
macrophages migration
Prior art date
Application number
PE2004000808A
Other languages
English (en)
Inventor
Jagadish Sircar
K C Sunil Kumar
Wenbin Ying
Original Assignee
Avanir Pharmaceuticals
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34272569&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20051112(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Avanir Pharmaceuticals filed Critical Avanir Pharmaceuticals
Publication of PE20051112A1 publication Critical patent/PE20051112A1/es

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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Abstract

SE REFIERE A UN COMPUESTO DE FORMULA I DONDE R ES H, ALQUILO, ALQUILO SUSTITUIDO, ALQUENILO, CICLOALQUILO, ENTRE OTROS; R1 ES -CN, -NO, -NO2, ENTRE OTROS; R2 ES -CH2R3, -OR3, ALQUILO, ENTRE OTROS; R3 ES ALQUILO, ALQUENILO, ARILO, ARILALQUILO, ENTRE OTROS; X ES H, HALOGENO, -NO, -OCF3, ENTRE OTROS; Y ES H, -NO2, -CF3, -CN, ENTRE OTROS; Z ES H, HALOGENO, -F, -NO, -OCF3, ENTRE OTROS; n ES 0-2. SON COMPUESTOS PREFERIDOS: A, B, C, ENTRE OTROS. SE REFIERE TEMBIEN A UN PROCESO DE PREPARACION. DICHOS COMPUESTOS SON INHIBIDORES DEL FACTOR INHIBIDOR DE LA MIGRACION DE MACROFAGOS UTILES EN EL TRATAMIENTO DE ARTRITIS REUMATOIDE, OSTEOARTRITIS, ENFERMEDAD INFLAMATORIA DEL INTESTINO Y ASMA
PE2004000808A 2003-08-22 2004-08-21 Derivados de naftiridina sustituidos como inhibidores del factor inhibidor de la migracion de macrofagos PE20051112A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49744303P 2003-08-22 2003-08-22

Publications (1)

Publication Number Publication Date
PE20051112A1 true PE20051112A1 (es) 2006-02-03

Family

ID=34272569

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2004000808A PE20051112A1 (es) 2003-08-22 2004-08-21 Derivados de naftiridina sustituidos como inhibidores del factor inhibidor de la migracion de macrofagos

Country Status (13)

Country Link
US (2) US20050124604A1 (es)
EP (1) EP1656376A1 (es)
JP (1) JP2007503388A (es)
CN (1) CN1839133A (es)
AR (1) AR045471A1 (es)
AU (1) AU2004268941A1 (es)
BR (1) BRPI0413695A (es)
CA (1) CA2531506A1 (es)
MX (1) MXJL06000006A (es)
PE (1) PE20051112A1 (es)
TW (1) TW200524928A (es)
UY (1) UY28483A1 (es)
WO (1) WO2005021546A1 (es)

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UY28483A1 (es) 2005-03-31
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MXJL06000006A (es) 2006-05-04
US20050124604A1 (en) 2005-06-09
CN1839133A (zh) 2006-09-27
US7361760B2 (en) 2008-04-22
EP1656376A1 (en) 2006-05-17
AR045471A1 (es) 2005-10-26
TW200524928A (en) 2005-08-01
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WO2005021546A1 (en) 2005-03-10
CA2531506A1 (en) 2005-03-10

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