PE20040417A1 - Forma de administracion de ibuprofeno sodico - Google Patents
Forma de administracion de ibuprofeno sodicoInfo
- Publication number
- PE20040417A1 PE20040417A1 PE2003001033A PE2003001033A PE20040417A1 PE 20040417 A1 PE20040417 A1 PE 20040417A1 PE 2003001033 A PE2003001033 A PE 2003001033A PE 2003001033 A PE2003001033 A PE 2003001033A PE 20040417 A1 PE20040417 A1 PE 20040417A1
- Authority
- PE
- Peru
- Prior art keywords
- sodium
- ibuprofen
- weight
- nucleus
- sugar
- Prior art date
Links
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 title abstract 5
- 229960001680 ibuprofen Drugs 0.000 title abstract 5
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 3
- 239000011734 sodium Substances 0.000 abstract 3
- 229910052708 sodium Inorganic materials 0.000 abstract 3
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 abstract 2
- 239000003826 tablet Substances 0.000 abstract 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000007938 effervescent tablet Substances 0.000 abstract 1
- 239000002360 explosive Substances 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910000027 potassium carbonate Inorganic materials 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
- 239000001488 sodium phosphate Substances 0.000 abstract 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 abstract 1
- 229940038773 trisodium citrate Drugs 0.000 abstract 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 abstract 1
- 229910000406 trisodium phosphate Inorganic materials 0.000 abstract 1
- 235000019801 trisodium phosphate Nutrition 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UNA TABLETA NO EFERVESCENTE PARA ADMINISTRACION ORAL DE IBUPROFENO SODICO, QUE CONSTA DE: 1)UN NUCLEO, QUE CONTIENE DE 50% A 100%, EN PESO, DE IBUPROFENO SODICO HIDRATADO Y DE 50% A 0%, EN PESO, DE COMPONENTE AUXILIAR, NO CONTENIENDO LUBRICANTE NI EXPLOSIVO ALGUNO; Y, 2)EVENTUALMENTE UNA CUBIERTA DE AZUCAR O UNA PELICULA SOBRE DICHO NUCLEO. DONDE, EL IBUPROFENO SODICO HIDRATADO TIENE UN CONTENIDO DE AGUA DE 8% A 16%, EN PESO, PORCENTAJE REFERIDO AL IBUPROFENO, Y EL COMPONENTE AUXILIAR, COMPRENDE UNO O VARIOS AUXILIARES BASICOS, SELECCIONADO DE: a)HIDROGENOCARBONATO SODICO, HIDROGENOCARBONATO POTASICO, CARBONATO SODICO, CARBONATO POTASICO, CITRATO TRISODICO Y FOSFATO TRISODICO. SE REFIERE TAMBIEN A UN PROCEDIMIENTO PARA LA FABRICACION DE LA TABLETA DESCRITA, QUE COMPRENDE: 1)PRENSAR EL IBUPROFENO SODICO HIDRATADO, QUE PUEDE ESTAR MEZCLADO CON EL AUXILIAR, PARA OBTENER NUCLEOS DE TABLETAS; Y, 2)APLICAR UNA CUBIERTA DE AZUCAR O PELICULAR AL NUCLEO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH01703/02A CH693586A8 (de) | 2002-10-14 | 2002-10-14 | Darreichungsform von Ibuprofen-Natrium. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20040417A1 true PE20040417A1 (es) | 2004-07-14 |
Family
ID=28796671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2003001033A PE20040417A1 (es) | 2002-10-14 | 2003-10-10 | Forma de administracion de ibuprofeno sodico |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US20040102522A1 (es) |
| EP (1) | EP1410793B1 (es) |
| JP (1) | JP4608316B2 (es) |
| KR (1) | KR101046894B1 (es) |
| CN (1) | CN100592909C (es) |
| AR (1) | AR041428A1 (es) |
| AT (1) | ATE309789T1 (es) |
| AU (1) | AU2003266094B2 (es) |
| BR (1) | BRPI0315248B1 (es) |
| CA (1) | CA2500987A1 (es) |
| CH (1) | CH693586A8 (es) |
| CO (1) | CO5700709A2 (es) |
| DE (1) | DE50301661D1 (es) |
| DK (1) | DK1410793T3 (es) |
| EA (1) | EA007914B1 (es) |
| EC (1) | ECSP055793A (es) |
| ES (1) | ES2249702T3 (es) |
| HR (1) | HRP20050429A2 (es) |
| IL (1) | IL167357A (es) |
| MA (1) | MA27490A1 (es) |
| MX (1) | MXPA05003592A (es) |
| MY (1) | MY132858A (es) |
| NO (1) | NO20052343L (es) |
| NZ (1) | NZ539405A (es) |
| PA (1) | PA8586101A1 (es) |
| PE (1) | PE20040417A1 (es) |
| PL (1) | PL376177A1 (es) |
| SI (1) | SI1410793T1 (es) |
| TW (1) | TWI262800B (es) |
| UA (1) | UA86751C2 (es) |
| WO (1) | WO2004035024A1 (es) |
| ZA (1) | ZA200502925B (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3920358A1 (de) * | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US6705028B2 (en) * | 2001-09-12 | 2004-03-16 | Honda Giken Kogyo Kabushiki Kaisha | Self-propelled snowplow vehicle |
| US20050176809A1 (en) * | 2004-02-05 | 2005-08-11 | Rodlen Laboratories, Inc. | Method and compositions for treatment of painful disorders |
| WO2006016125A1 (en) * | 2004-08-12 | 2006-02-16 | Reckitt Benckiser Healthcare (Uk) Limited | Granules comprising a nsaid and a sugar alcohol made by melt extrusion |
| US20070077297A1 (en) * | 2004-09-30 | 2007-04-05 | Scolr Pharma, Inc. | Modified release ibuprofen dosage form |
| WO2006093353A1 (ja) | 2005-03-03 | 2006-09-08 | Takeda Pharmaceutical Company Limited | 放出制御組成物 |
| US9205054B2 (en) | 2005-03-22 | 2015-12-08 | Losan Pharma Gmbh | Solubilized ibuprofen |
| EP1800667A1 (en) | 2005-12-23 | 2007-06-27 | Losan Pharma GmbH | Rapidly solubilizing ibuprofen granulate |
| DE102006029233A1 (de) * | 2006-06-26 | 2007-12-27 | Liedtke, Rainer K., Dr. | Formulierungen zur Verbesserung der Verträglichkeit nichtsteroidaler Antiphlogistika |
| CL2007002425A1 (es) * | 2006-08-22 | 2008-06-27 | Albermarle Corp | Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica. |
| FI20080348A0 (fi) * | 2008-02-15 | 2008-05-09 | Atacama Labs Oy | Uudenlainen farmaseuttinen formulaatio |
| US7749537B2 (en) * | 2006-12-04 | 2010-07-06 | Scolr Pharma, Inc. | Method of forming a tablet |
| WO2010011522A1 (en) * | 2008-07-21 | 2010-01-28 | Albemarle Corporation | High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms |
| US9629809B2 (en) | 2008-07-21 | 2017-04-25 | Si Group, Inc. | High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms |
| US20110144207A1 (en) * | 2008-08-14 | 2011-06-16 | Shasun Chemicals And Drugs Limited | Aryl alkyl carboxylic acid salts, process for preparation and dosage forms |
| UA102128C2 (en) * | 2008-12-05 | 2013-06-10 | Х. Луннбек А/С | Nalmefene hydrochloride dihydrate |
| AU2015264861C1 (en) * | 2009-06-22 | 2017-11-16 | Pf Consumer Healthcare 1 Llc | Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen |
| AU2014200704C1 (en) * | 2009-06-22 | 2018-12-06 | Pf Consumer Healthcare 1 Llc | Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen |
| JP2012530781A (ja) * | 2009-06-22 | 2012-12-06 | ワイス・エルエルシー | イブプロフェンナトリウムタブレット、およびイブプロフェンナトリウムを含有する医薬組成物の製造方法 |
| FR2997856B1 (fr) * | 2012-11-14 | 2015-04-24 | Pf Medicament | Pastille medicamenteuse a base d'ibuprofene sodique dihydrate |
| EP2965746B1 (en) | 2014-07-10 | 2019-03-13 | Santa Farma Ilaç Sanayi A.S. | An oral pharmaceutical composition comprising ibuprofen, ibuprofen sodium dihydrate, pseudoephedrine hydrochloride and chlorpheniramine maleate |
| US20180078516A1 (en) * | 2016-09-19 | 2018-03-22 | Innovazone Labs LLC | Pharmaceutical Composition of Ibuprofen Sodium for Oral Administration |
| CN113893227B (zh) * | 2021-11-18 | 2023-04-14 | 山东则正医药技术有限公司 | 布洛芬片的制备原料、制备方法和布洛芬片 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5104648A (en) * | 1989-02-02 | 1992-04-14 | Mallinckrodt Specialty Chemicals Company | High ibuprofen content granulations |
| GB8920693D0 (en) * | 1989-09-13 | 1989-10-25 | Nicholas Kiwi Pty Ltd | Non-effervescent ibuprofen compositions |
| CA2061520C (en) * | 1991-03-27 | 2003-04-22 | Lawrence J. Daher | Delivery system for enhanced onset and increased potency |
| GB9224021D0 (en) * | 1992-11-16 | 1993-01-06 | Boots Co Plc | Effervescent compositions |
| US6083430A (en) * | 1994-10-28 | 2000-07-04 | Fuisz Technologies Ltd. | Method of preparing a dosage unit by direct tableting and product therefrom |
| GB9603699D0 (en) * | 1996-02-21 | 1996-04-17 | Boots Co Plc | Therapeutic composition |
| IT1301966B1 (it) * | 1998-07-30 | 2000-07-20 | Zambon Spa | Composizioni farmaceutiche ad attivita' analgesica |
-
2002
- 2002-10-14 CH CH01703/02A patent/CH693586A8/de not_active IP Right Cessation
-
2003
- 2003-04-03 SI SI200330125T patent/SI1410793T1/sl unknown
- 2003-04-03 DK DK03405225T patent/DK1410793T3/da active
- 2003-04-03 EP EP03405225A patent/EP1410793B1/de not_active Expired - Lifetime
- 2003-04-03 AT AT03405225T patent/ATE309789T1/de not_active IP Right Cessation
- 2003-04-03 DE DE50301661T patent/DE50301661D1/de not_active Expired - Fee Related
- 2003-04-03 ES ES03405225T patent/ES2249702T3/es not_active Expired - Lifetime
- 2003-09-10 UA UAA200504484A patent/UA86751C2/ru unknown
- 2003-09-22 TW TW092126096A patent/TWI262800B/zh active
- 2003-09-29 AR ARP030103544A patent/AR041428A1/es unknown
- 2003-09-30 MY MYPI20033728A patent/MY132858A/en unknown
- 2003-10-09 KR KR1020057006414A patent/KR101046894B1/ko active IP Right Grant
- 2003-10-09 CN CN200380101345A patent/CN100592909C/zh not_active Expired - Fee Related
- 2003-10-09 EA EA200500649A patent/EA007914B1/ru not_active IP Right Cessation
- 2003-10-09 CA CA002500987A patent/CA2500987A1/en not_active Abandoned
- 2003-10-09 BR BRPI0315248A patent/BRPI0315248B1/pt not_active IP Right Cessation
- 2003-10-09 AU AU2003266094A patent/AU2003266094B2/en not_active Expired - Fee Related
- 2003-10-09 MX MXPA05003592A patent/MXPA05003592A/es active IP Right Grant
- 2003-10-09 JP JP2004543886A patent/JP4608316B2/ja not_active Expired - Fee Related
- 2003-10-09 NZ NZ539405A patent/NZ539405A/en unknown
- 2003-10-09 PL PL03376177A patent/PL376177A1/xx not_active Application Discontinuation
- 2003-10-09 WO PCT/CH2003/000662 patent/WO2004035024A1/en active Application Filing
- 2003-10-10 PE PE2003001033A patent/PE20040417A1/es not_active Application Discontinuation
- 2003-10-13 PA PA20038586101A patent/PA8586101A1/es unknown
- 2003-10-14 US US10/683,283 patent/US20040102522A1/en not_active Abandoned
-
2005
- 2005-03-09 IL IL167357A patent/IL167357A/en not_active IP Right Cessation
- 2005-04-11 ZA ZA200502925A patent/ZA200502925B/en unknown
- 2005-05-09 MA MA28268A patent/MA27490A1/fr unknown
- 2005-05-10 CO CO05044513A patent/CO5700709A2/es not_active Application Discontinuation
- 2005-05-12 NO NO20052343A patent/NO20052343L/no not_active Application Discontinuation
- 2005-05-13 EC EC2005005793A patent/ECSP055793A/es unknown
- 2005-05-13 HR HR20050429A patent/HRP20050429A2/xx not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |