AR041428A1 - Forma de dosificacion de ibuprofeno sodico - Google Patents
Forma de dosificacion de ibuprofeno sodicoInfo
- Publication number
- AR041428A1 AR041428A1 ARP030103544A ARP030103544A AR041428A1 AR 041428 A1 AR041428 A1 AR 041428A1 AR P030103544 A ARP030103544 A AR P030103544A AR P030103544 A ARP030103544 A AR P030103544A AR 041428 A1 AR041428 A1 AR 041428A1
- Authority
- AR
- Argentina
- Prior art keywords
- weight
- ibuprofen
- sodium ibuprofen
- tablet core
- hydrated sodium
- Prior art date
Links
- PTTPUWGBPLLBKW-UHFFFAOYSA-M sodium;2-[4-(2-methylpropyl)phenyl]propanoate Chemical compound [Na+].CC(C)CC1=CC=C(C(C)C([O-])=O)C=C1 PTTPUWGBPLLBKW-UHFFFAOYSA-M 0.000 title abstract 5
- 239000002552 dosage form Substances 0.000 title 1
- 239000003826 tablet Substances 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000036765 blood level Effects 0.000 abstract 1
- 239000007884 disintegrant Substances 0.000 abstract 1
- 239000007938 effervescent tablet Substances 0.000 abstract 1
- 229960001680 ibuprofen Drugs 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una tableta no efervescente de ibuprofeno sódico que comprende un núcleo de tableta y, si se desea, una cubierta de azúcar o de película, en la cual el núcleo de tableta, con referencia al peso del núcleo de tableta, consiste en de 50 a 100% en peso de ibuprofeno sódico hidratado y de 50 a 0% en peso de componente de material auxiliar, no conteniendo ni lubricante ni disgregante, y en la cual el ibuprofeno sódico hidratado tiene un contenido de agua de desde 8 a 16% en peso, preferentemente de desde 11 a 16% en peso, posee una dureza suficiente, es comparativamente pequena y produce un incremento particularmente rápido en el nivel en sangre y con ello un comienzo acelerado del efecto analgésico. En oposición a la doctrina corriente el ibuprofeno sódico hidratado que tiene un contenido de agua adecuado es suficientemente comprensible.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH01703/02A CH693586A8 (de) | 2002-10-14 | 2002-10-14 | Darreichungsform von Ibuprofen-Natrium. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR041428A1 true AR041428A1 (es) | 2005-05-18 |
Family
ID=28796671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030103544A AR041428A1 (es) | 2002-10-14 | 2003-09-29 | Forma de dosificacion de ibuprofeno sodico |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US20040102522A1 (es) |
| EP (1) | EP1410793B1 (es) |
| JP (1) | JP4608316B2 (es) |
| KR (1) | KR101046894B1 (es) |
| CN (1) | CN100592909C (es) |
| AR (1) | AR041428A1 (es) |
| AT (1) | ATE309789T1 (es) |
| AU (1) | AU2003266094B2 (es) |
| BR (1) | BRPI0315248B1 (es) |
| CA (1) | CA2500987A1 (es) |
| CH (1) | CH693586A8 (es) |
| CO (1) | CO5700709A2 (es) |
| DE (1) | DE50301661D1 (es) |
| DK (1) | DK1410793T3 (es) |
| EA (1) | EA007914B1 (es) |
| EC (1) | ECSP055793A (es) |
| ES (1) | ES2249702T3 (es) |
| HR (1) | HRP20050429A2 (es) |
| IL (1) | IL167357A (es) |
| MA (1) | MA27490A1 (es) |
| MX (1) | MXPA05003592A (es) |
| MY (1) | MY132858A (es) |
| NO (1) | NO20052343L (es) |
| NZ (1) | NZ539405A (es) |
| PA (1) | PA8586101A1 (es) |
| PE (1) | PE20040417A1 (es) |
| PL (1) | PL376177A1 (es) |
| SI (1) | SI1410793T1 (es) |
| TW (1) | TWI262800B (es) |
| UA (1) | UA86751C2 (es) |
| WO (1) | WO2004035024A1 (es) |
| ZA (1) | ZA200502925B (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3920358A1 (de) * | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US6705028B2 (en) * | 2001-09-12 | 2004-03-16 | Honda Giken Kogyo Kabushiki Kaisha | Self-propelled snowplow vehicle |
| US20050176809A1 (en) * | 2004-02-05 | 2005-08-11 | Rodlen Laboratories, Inc. | Method and compositions for treatment of painful disorders |
| CA2576642A1 (en) * | 2004-08-12 | 2006-02-16 | Reckitt Benckiser Healthcare (Uk) Limited | Granules comprising a nsaid and a sugar alcohol made by melt extrusion |
| US20070077297A1 (en) * | 2004-09-30 | 2007-04-05 | Scolr Pharma, Inc. | Modified release ibuprofen dosage form |
| CA2610343A1 (en) | 2005-03-03 | 2006-09-08 | Takeda Pharmaceutical Company Limited | Release-control composition |
| JP2008534477A (ja) | 2005-03-22 | 2008-08-28 | ロザン ファルマ ゲゼルシャフトミットベシュレンクテルハフツンク | 可溶化イブプロフェン |
| EP1800667A1 (en) | 2005-12-23 | 2007-06-27 | Losan Pharma GmbH | Rapidly solubilizing ibuprofen granulate |
| DE102006029233A1 (de) * | 2006-06-26 | 2007-12-27 | Liedtke, Rainer K., Dr. | Formulierungen zur Verbesserung der Verträglichkeit nichtsteroidaler Antiphlogistika |
| CL2007002425A1 (es) * | 2006-08-22 | 2008-06-27 | Albermarle Corp | Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica. |
| FI20080348A0 (fi) * | 2008-02-15 | 2008-05-09 | Atacama Labs Oy | Uudenlainen farmaseuttinen formulaatio |
| US7749537B2 (en) * | 2006-12-04 | 2010-07-06 | Scolr Pharma, Inc. | Method of forming a tablet |
| EP2309988B1 (en) * | 2008-07-21 | 2015-11-25 | SI Group, Inc. | High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms |
| US9629809B2 (en) | 2008-07-21 | 2017-04-25 | Si Group, Inc. | High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms |
| WO2011001228A1 (en) * | 2008-08-14 | 2011-01-06 | Shasun Chemicals And Drugs Limited | Aryl alkyl carboxylic acid salts, process for preparation and dosage forms |
| UA102128C2 (en) * | 2008-12-05 | 2013-06-10 | Х. Луннбек А/С | Nalmefene hydrochloride dihydrate |
| AU2014200704C1 (en) * | 2009-06-22 | 2018-12-06 | Pf Consumer Healthcare 1 Llc | Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen |
| HUE037827T2 (hu) * | 2009-06-22 | 2018-09-28 | Wyeth Llc | Nátrium-ibuprofen tabletták és eljárások nátrium-ibuprofent tartalmazó gyógyszerészeti készítmények elõállítására |
| AU2015264861C1 (en) * | 2009-06-22 | 2017-11-16 | Pf Consumer Healthcare 1 Llc | Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen |
| FR2997856B1 (fr) * | 2012-11-14 | 2015-04-24 | Pf Medicament | Pastille medicamenteuse a base d'ibuprofene sodique dihydrate |
| EP2965746B1 (en) | 2014-07-10 | 2019-03-13 | Santa Farma Ilaç Sanayi A.S. | An oral pharmaceutical composition comprising ibuprofen, ibuprofen sodium dihydrate, pseudoephedrine hydrochloride and chlorpheniramine maleate |
| US20180078516A1 (en) * | 2016-09-19 | 2018-03-22 | Innovazone Labs LLC | Pharmaceutical Composition of Ibuprofen Sodium for Oral Administration |
| CN113893227B (zh) * | 2021-11-18 | 2023-04-14 | 山东则正医药技术有限公司 | 布洛芬片的制备原料、制备方法和布洛芬片 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5104648A (en) * | 1989-02-02 | 1992-04-14 | Mallinckrodt Specialty Chemicals Company | High ibuprofen content granulations |
| GB8920693D0 (en) * | 1989-09-13 | 1989-10-25 | Nicholas Kiwi Pty Ltd | Non-effervescent ibuprofen compositions |
| CA2061520C (en) * | 1991-03-27 | 2003-04-22 | Lawrence J. Daher | Delivery system for enhanced onset and increased potency |
| GB9224021D0 (en) * | 1992-11-16 | 1993-01-06 | Boots Co Plc | Effervescent compositions |
| US6083430A (en) * | 1994-10-28 | 2000-07-04 | Fuisz Technologies Ltd. | Method of preparing a dosage unit by direct tableting and product therefrom |
| GB9603699D0 (en) * | 1996-02-21 | 1996-04-17 | Boots Co Plc | Therapeutic composition |
| IT1301966B1 (it) * | 1998-07-30 | 2000-07-20 | Zambon Spa | Composizioni farmaceutiche ad attivita' analgesica |
-
2002
- 2002-10-14 CH CH01703/02A patent/CH693586A8/de not_active IP Right Cessation
-
2003
- 2003-04-03 DK DK03405225T patent/DK1410793T3/da active
- 2003-04-03 DE DE50301661T patent/DE50301661D1/de not_active Expired - Fee Related
- 2003-04-03 EP EP03405225A patent/EP1410793B1/de not_active Expired - Lifetime
- 2003-04-03 ES ES03405225T patent/ES2249702T3/es not_active Expired - Lifetime
- 2003-04-03 AT AT03405225T patent/ATE309789T1/de not_active IP Right Cessation
- 2003-04-03 SI SI200330125T patent/SI1410793T1/sl unknown
- 2003-09-10 UA UAA200504484A patent/UA86751C2/ru unknown
- 2003-09-22 TW TW092126096A patent/TWI262800B/zh active
- 2003-09-29 AR ARP030103544A patent/AR041428A1/es unknown
- 2003-09-30 MY MYPI20033728A patent/MY132858A/en unknown
- 2003-10-09 MX MXPA05003592A patent/MXPA05003592A/es active IP Right Grant
- 2003-10-09 AU AU2003266094A patent/AU2003266094B2/en not_active Expired - Fee Related
- 2003-10-09 NZ NZ539405A patent/NZ539405A/en unknown
- 2003-10-09 BR BRPI0315248A patent/BRPI0315248B1/pt not_active IP Right Cessation
- 2003-10-09 CN CN200380101345A patent/CN100592909C/zh not_active Expired - Fee Related
- 2003-10-09 KR KR1020057006414A patent/KR101046894B1/ko active IP Right Grant
- 2003-10-09 WO PCT/CH2003/000662 patent/WO2004035024A1/en active Application Filing
- 2003-10-09 CA CA002500987A patent/CA2500987A1/en not_active Abandoned
- 2003-10-09 PL PL03376177A patent/PL376177A1/xx not_active Application Discontinuation
- 2003-10-09 JP JP2004543886A patent/JP4608316B2/ja not_active Expired - Fee Related
- 2003-10-09 EA EA200500649A patent/EA007914B1/ru not_active IP Right Cessation
- 2003-10-10 PE PE2003001033A patent/PE20040417A1/es not_active Application Discontinuation
- 2003-10-13 PA PA20038586101A patent/PA8586101A1/es unknown
- 2003-10-14 US US10/683,283 patent/US20040102522A1/en not_active Abandoned
-
2005
- 2005-03-09 IL IL167357A patent/IL167357A/en not_active IP Right Cessation
- 2005-04-11 ZA ZA200502925A patent/ZA200502925B/en unknown
- 2005-05-09 MA MA28268A patent/MA27490A1/fr unknown
- 2005-05-10 CO CO05044513A patent/CO5700709A2/es not_active Application Discontinuation
- 2005-05-12 NO NO20052343A patent/NO20052343L/no not_active Application Discontinuation
- 2005-05-13 EC EC2005005793A patent/ECSP055793A/es unknown
- 2005-05-13 HR HR20050429A patent/HRP20050429A2/xx not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |