PE20030948A1 - Proceso para la preparacion de una suspension esteril de particulas de dipropionato de beclometasona para administracion por inhalacion - Google Patents
Proceso para la preparacion de una suspension esteril de particulas de dipropionato de beclometasona para administracion por inhalacionInfo
- Publication number
- PE20030948A1 PE20030948A1 PE2003000389A PE2003000389A PE20030948A1 PE 20030948 A1 PE20030948 A1 PE 20030948A1 PE 2003000389 A PE2003000389 A PE 2003000389A PE 2003000389 A PE2003000389 A PE 2003000389A PE 20030948 A1 PE20030948 A1 PE 20030948A1
- Authority
- PE
- Peru
- Prior art keywords
- turbine
- beclometasone dipropionate
- istiling
- corticosteroid
- suspension
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
QUE COMPRENDE: 1)AGREGAR UNO O MAS INGREDIENTES ACTIVOS, TAL COMO UN CORTICOSTEROIDE, BAJO LA FORMA DE UN POLVO ESTERIL MICRONIZADO, A UNA SOLUCION ACUOSA QUE CONSTITUYE EL VEHICULO, LA CUAL CONTIENE ADITIVOS O EXCIPIENTES SELECCIONADOS ENTRE AGENTES HUMECTANTES, ESTABILIZADORES, ISOTONICOS Y/O AMORTIGUADORES, EN UN TURBO EMULSIFICADOR EQUIPADO CON UNA TURBINA DE ALTO PODER Y CONECTADO A UNA TOLVA DE CARGA, INTRODUCIENDO LOS INGREDIENTES ACTIVOS A TRAVES DE LA TURBINA DESPUES DE APLICAR EL VACIO; 2)HOMOGENEIZAR EL INGREDIENTE ACTIVO EN LA SUSPENSION, AUN AL VACIO, USANDO EL SISTEMA DE TURBINA, A UNA VELOCIDAD ENTRE 750 rpm Y 4000 rpm DURANTE 10 min A 60 min; Y, 3)DISTRIBUIR LA SUSPENSION OBTENIDA DE ESTE MODO EN RECIPIENTES ADECUADOS DE DOSIS INDIVIDUALES . DONDE, EL PROCESO SE REALIZA BAJO CONDICIONES ESTERILES, AGREGANDO UN CORTICOSTEROIDE, TAL COMO DIPROPIONATO DE BECLOMETASONA, ESTERILIZADO POR IRRADIACION O CALENTAMIENTO. SE REFIERE TAMBIEN A FORMULACIONES FARMACEUTICAS QUE SE UTILIZAN PARA NEBULIZACION, EN EL TRATAMIENTO DE ENFERMEDADES PULMONARES, QUE CONSTAN DE DOSIS UNITARIAS QUE CONTIENEN SUSPENSIONES ACUOSAS OBTENIDAS EN EL PROCESO ANTES DESCRITO
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002MI000808A ITMI20020808A1 (it) | 2002-04-17 | 2002-04-17 | Procedimento per la preparazione di una sospensione sterile di particelle di beclometasone dipropionato da somministrare per inalazione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20030948A1 true PE20030948A1 (es) | 2004-01-19 |
Family
ID=11449718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2003000389A PE20030948A1 (es) | 2002-04-17 | 2003-04-16 | Proceso para la preparacion de una suspension esteril de particulas de dipropionato de beclometasona para administracion por inhalacion |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7541021B2 (es) |
| EP (1) | EP1494647B1 (es) |
| CN (1) | CN1292733C (es) |
| AR (1) | AR039317A1 (es) |
| AT (1) | ATE338539T1 (es) |
| AU (1) | AU2003227627A1 (es) |
| BR (1) | BRPI0304821B8 (es) |
| CA (1) | CA2481520C (es) |
| CY (1) | CY1105800T1 (es) |
| DE (1) | DE60308164T2 (es) |
| DK (1) | DK1494647T3 (es) |
| EA (1) | EA007629B1 (es) |
| ES (1) | ES2272987T3 (es) |
| HK (1) | HK1079986B (es) |
| HR (1) | HRP20040964A2 (es) |
| IT (1) | ITMI20020808A1 (es) |
| MA (1) | MA27194A1 (es) |
| MX (1) | MXPA04010117A (es) |
| PE (1) | PE20030948A1 (es) |
| PL (1) | PL207863B1 (es) |
| PT (1) | PT1494647E (es) |
| SI (1) | SI1494647T1 (es) |
| UA (1) | UA79453C2 (es) |
| WO (1) | WO2003086347A1 (es) |
| ZA (1) | ZA200408319B (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1572217B1 (en) * | 2002-12-12 | 2008-08-20 | Nycomed GmbH | Combination medicament of r,r-formoterol and ciclesonide |
| PL1670482T5 (pl) * | 2003-09-16 | 2022-10-03 | Covis Pharma Gmbh | Zastosowanie cyklezonidu w leczeniu chorób układu oddechowego |
| ES2315721T5 (es) * | 2003-10-23 | 2012-08-24 | Otsuka Pharmaceutical Co., Ltd. | Formulación de aripiprazol inyectable estéril de liberación controlada y procedimiento |
| PE20050941A1 (es) * | 2003-12-16 | 2005-11-08 | Nycomed Gmbh | Suspensiones acuosas de ciclesonida para nebulizacion |
| US20070020298A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid |
| US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
| CA2563556C (en) * | 2004-04-20 | 2013-01-29 | Altana Pharma Ag | Use of ciclesonide for the treatment of respiratory diseases in a smoking patient |
| GB0425266D0 (en) | 2004-11-16 | 2004-12-15 | Norton Healthcare Ltd | Pharmaceutical manufacturing process |
| ES2388287T3 (es) | 2005-01-20 | 2012-10-11 | Eratech S.R.L. | Procedimiento para la preparación de suspensiones concentradas de fármacos y kit correspondiente |
| WO2007035348A2 (en) * | 2005-09-15 | 2007-03-29 | Elan Pharma International, Limited | Nanoparticulate aripiprazole formulations |
| US20070099883A1 (en) * | 2005-10-07 | 2007-05-03 | Cheryl Lynn Calis | Anhydrous mometasone furoate formulation |
| CA2642641A1 (en) * | 2006-02-15 | 2007-08-23 | Tika Laekemedel Ab | Stable corticosteroid mixtures |
| PL2170348T3 (pl) * | 2007-06-22 | 2017-01-31 | Dompé Farmaceutici S.P.A. | Tabletki musujące do zastosowania wziewnego |
| LT2170279T (lt) * | 2007-07-31 | 2018-03-12 | Otsuka Pharmaceutical Co., Ltd. | Aripiprazolo suspensijos ir liofilizuotos kompozicijos gamybos būdai |
| CN102475708A (zh) * | 2010-11-23 | 2012-05-30 | 天津金耀集团有限公司 | 丙酸氟替卡松和含辅料的水构成的治疗皮肤病的分离式水混悬剂药物 |
| CN102657659A (zh) * | 2010-11-23 | 2012-09-12 | 天津金耀集团有限公司 | 皮肤用含有辅料的丙酸氟替卡松与含有辅料的水的透皮吸收药物 |
| RU2611665C2 (ru) | 2011-05-03 | 2017-02-28 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Улучшенный состав суспензии кортикостероида для ингаляционного введения |
| CN103505412A (zh) * | 2012-06-26 | 2014-01-15 | 上海臣邦医药科技有限公司 | 一种吸入用丙酸氟替卡松混悬液的制备方法 |
| WO2022098321A1 (en) * | 2020-11-09 | 2022-05-12 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Process for the preparation of sterilised suspensions for the administration by inhalation |
| WO2022231533A1 (en) * | 2021-04-29 | 2022-11-03 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Process for the preparation of sterilized suspensions for the inhalation by nebulization |
| WO2022231531A1 (en) * | 2021-04-29 | 2022-11-03 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Process for the preparation of sterilized suspensions for the inhalation by nebulization |
| WO2023022672A2 (en) * | 2021-08-18 | 2023-02-23 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Process for the preparation of homogeneous suspensions for the inhalation by nebulization |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1303692B1 (it) * | 1998-11-03 | 2001-02-23 | Chiesi Farma Spa | Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione. |
| ITMI20022674A1 (it) * | 2002-12-18 | 2004-06-19 | Chiesi Farma Spa | Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione. |
-
2002
- 2002-04-17 IT IT2002MI000808A patent/ITMI20020808A1/it unknown
-
2003
- 2003-04-15 EA EA200401209A patent/EA007629B1/ru unknown
- 2003-04-15 WO PCT/EP2003/003916 patent/WO2003086347A1/en active IP Right Grant
- 2003-04-15 EP EP03725033A patent/EP1494647B1/en not_active Expired - Lifetime
- 2003-04-15 BR BRPI0304821A patent/BRPI0304821B8/pt not_active IP Right Cessation
- 2003-04-15 SI SI200330532T patent/SI1494647T1/sl unknown
- 2003-04-15 UA UA20041008327A patent/UA79453C2/uk unknown
- 2003-04-15 CN CNB038111608A patent/CN1292733C/zh not_active Expired - Lifetime
- 2003-04-15 PT PT03725033T patent/PT1494647E/pt unknown
- 2003-04-15 PL PL373331A patent/PL207863B1/pl unknown
- 2003-04-15 MX MXPA04010117A patent/MXPA04010117A/es active IP Right Grant
- 2003-04-15 ES ES03725033T patent/ES2272987T3/es not_active Expired - Lifetime
- 2003-04-15 US US10/510,232 patent/US7541021B2/en not_active Expired - Fee Related
- 2003-04-15 DK DK03725033T patent/DK1494647T3/da active
- 2003-04-15 AU AU2003227627A patent/AU2003227627A1/en not_active Abandoned
- 2003-04-15 DE DE60308164T patent/DE60308164T2/de not_active Expired - Lifetime
- 2003-04-15 AT AT03725033T patent/ATE338539T1/de active
- 2003-04-15 CA CA2481520A patent/CA2481520C/en not_active Expired - Fee Related
- 2003-04-16 AR ARP030101350A patent/AR039317A1/es unknown
- 2003-04-16 PE PE2003000389A patent/PE20030948A1/es not_active Application Discontinuation
-
2004
- 2004-10-08 MA MA27897A patent/MA27194A1/fr unknown
- 2004-10-14 ZA ZA200408319A patent/ZA200408319B/xx unknown
- 2004-10-14 HR HR20040964A patent/HRP20040964A2/hr not_active Application Discontinuation
-
2006
- 2006-01-04 HK HK06100045.9A patent/HK1079986B/zh not_active IP Right Cessation
- 2006-11-21 CY CY20061101689T patent/CY1105800T1/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |