PE20020589A1 - 5-espiropirimidin-2,4,6-triona como inhibidores de metaloproteinasas - Google Patents

5-espiropirimidin-2,4,6-triona como inhibidores de metaloproteinasas

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Publication number
PE20020589A1
PE20020589A1 PE2001001060A PE2001001060A PE20020589A1 PE 20020589 A1 PE20020589 A1 PE 20020589A1 PE 2001001060 A PE2001001060 A PE 2001001060A PE 2001001060 A PE2001001060 A PE 2001001060A PE 20020589 A1 PE20020589 A1 PE 20020589A1
Authority
PE
Peru
Prior art keywords
heteroaryl
aryl
alkyl
spiropyrimidin
triona
Prior art date
Application number
PE2001001060A
Other languages
English (en)
Spanish (es)
Inventor
Brian Scott Bronk
Mark Carl Noe
Martin James Wythes
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PE20020589A1 publication Critical patent/PE20020589A1/es

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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
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    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
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PE2001001060A 2000-10-26 2001-10-25 5-espiropirimidin-2,4,6-triona como inhibidores de metaloproteinasas PE20020589A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24338900P 2000-10-26 2000-10-26

Publications (1)

Publication Number Publication Date
PE20020589A1 true PE20020589A1 (es) 2002-07-06

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PE2001001060A PE20020589A1 (es) 2000-10-26 2001-10-25 5-espiropirimidin-2,4,6-triona como inhibidores de metaloproteinasas

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EP (1) EP1332146A2 (ko)
JP (1) JP2004518635A (ko)
KR (1) KR20040004412A (ko)
CN (1) CN1501937A (ko)
AP (1) AP2001002318A0 (ko)
AR (1) AR035069A1 (ko)
AU (1) AU2002210813A1 (ko)
BG (1) BG107653A (ko)
BR (1) BR0114913A (ko)
CA (1) CA2425283A1 (ko)
CZ (1) CZ20031083A3 (ko)
EA (1) EA005762B1 (ko)
EC (1) ECSP034567A (ko)
EE (1) EE200300196A (ko)
GT (1) GT200100213A (ko)
HN (1) HN2001000244A (ko)
HR (1) HRP20030332A2 (ko)
HU (1) HUP0301577A3 (ko)
IL (1) IL154948A0 (ko)
IS (1) IS6762A (ko)
MA (1) MA26957A1 (ko)
MX (1) MXPA03003735A (ko)
NO (1) NO20031853L (ko)
OA (1) OA12529A (ko)
PA (1) PA8531401A1 (ko)
PE (1) PE20020589A1 (ko)
PL (1) PL366201A1 (ko)
SK (1) SK4972003A3 (ko)
SV (1) SV2003000705A (ko)
TN (1) TNSN01149A1 (ko)
WO (1) WO2002034753A2 (ko)
ZA (1) ZA200302190B (ko)

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DOP2002000333A (es) 2001-02-14 2002-09-30 Warner Lambert Co Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz
BR0207865A (pt) 2001-02-14 2004-03-23 Warner Lambert Co Benzotiadiazinas inibidores de metaloproteinases de matriz
DOP2002000332A (es) 2001-02-14 2002-08-30 Warner Lambert Co Inhibidores de piridina de metaloproteinasas de la matriz
PA8539501A1 (es) 2001-02-14 2002-09-30 Warner Lambert Co Compuestos triazolo como inhibidores de mmp
DOP2002000328A (es) 2001-02-14 2003-08-30 Warner Lambert Co Pirimidinas inhibidoras de metaloproteinasas de matriz
US6924276B2 (en) 2001-09-10 2005-08-02 Warner-Lambert Company Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors
US6962922B2 (en) 2001-10-12 2005-11-08 Warner-Lambert Company Llc Alkynylated quinazoline compounds
BR0213233A (pt) 2001-10-12 2005-01-04 Warner Lambert Co Alcinos inibidores de metaloproteinase de matriz
US6894057B2 (en) 2002-03-08 2005-05-17 Warner-Lambert Company Oxo-azabicyclic compounds
WO2003091252A1 (en) * 2002-04-25 2003-11-06 Bristol-Myers Squibb Company Spirobarbituric acid derivatives useful as inhibitors of matrix metalloproteases
AU2003219410A1 (en) * 2002-04-26 2003-11-10 Pfizer Products Inc. Triaryl-oxy-aryl-spiro-pyrimidine-2, 4, 6-trione metalloproteinase inhibitors
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