PE20001600A1 - Derivados de 1,4-diazabiciclo (3.3.2) nonan-4-carboxilatos y carboxamidas, su preparacion y su aplicacion en terapeutica - Google Patents
Derivados de 1,4-diazabiciclo (3.3.2) nonan-4-carboxilatos y carboxamidas, su preparacion y su aplicacion en terapeuticaInfo
- Publication number
- PE20001600A1 PE20001600A1 PE2000000274A PE0002742000A PE20001600A1 PE 20001600 A1 PE20001600 A1 PE 20001600A1 PE 2000000274 A PE2000000274 A PE 2000000274A PE 0002742000 A PE0002742000 A PE 0002742000A PE 20001600 A1 PE20001600 A1 PE 20001600A1
- Authority
- PE
- Peru
- Prior art keywords
- nonan
- carboxamides
- derivatives
- carboxylates
- diazabicyclo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A DERIVADOS DE 1,4-DIAZABICICLO [3.2.2] NONAN-4-CARBOXILATOS Y CARBOXAMIDAS DE FORMULA (I), DONDE: X ES O, NZ; Z ES H, ALQUILO C1-C6; n ES 0-2; R1-R5 SON H, HALOGENO, TRIFLUOROMETILO, TRIFLUOROMETOXI, CIANO, OH, ALQUILO C1-C6, FENOXI, FENILO, ENTRE OTROS; O R2 Y R3 JUNTOS SON -OCH2O-, -(CH2)4-. LOS DERIVADOS DE 1,4-DIAZABICICLO [3.2.2] NONAN-4-CARBOXILATO Y CARBOXAMIDAS TIENEN AFINIDAD POR LOS RECEPTORES NICOTINICOS QUE CONTIENEN LA SUBUNIDAD ALFA Y PUEDEN SER UTILES PARA TRATAMIENTO O PREVENCION DE LOS DESORDENES A NIVEL DEL SITEMA NERVIOSO CENTRAL O DEL SISTEMA GASTROINTESTINAL
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9903934A FR2791678B1 (fr) | 1999-03-30 | 1999-03-30 | Derives de 1,4-diazabicyclo [3.2.2] nonane-4-carboxylates et -carboxamides, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20001600A1 true PE20001600A1 (es) | 2001-04-01 |
Family
ID=9543787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2000000274A PE20001600A1 (es) | 1999-03-30 | 2000-03-30 | Derivados de 1,4-diazabiciclo (3.3.2) nonan-4-carboxilatos y carboxamidas, su preparacion y su aplicacion en terapeutica |
Country Status (15)
Country | Link |
---|---|
US (1) | US6987106B1 (es) |
EP (1) | EP1165559B1 (es) |
JP (1) | JP4500454B2 (es) |
AR (1) | AR023188A1 (es) |
AT (1) | ATE232865T1 (es) |
AU (1) | AU3301800A (es) |
CO (1) | CO5180557A1 (es) |
DE (1) | DE60001451T2 (es) |
DK (1) | DK1165559T3 (es) |
ES (1) | ES2192520T3 (es) |
FR (1) | FR2791678B1 (es) |
PE (1) | PE20001600A1 (es) |
TW (1) | TWI221843B (es) |
UY (1) | UY26082A1 (es) |
WO (1) | WO2000058311A1 (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60109924T2 (de) | 2000-05-25 | 2006-02-09 | Targacept, Inc. | Heteroaryldiazabicycloalkane als liganden für den nikotinischen acetylcholin-rezeptor |
US6624167B1 (en) | 2000-08-04 | 2003-09-23 | Targacept, Inc. | Pharmaceutical compositions and methods for use |
ES2275808T3 (es) * | 2001-02-06 | 2007-06-16 | Pfizer Products Inc. | Composiciones farmaceuticas para el tratamiento de trastornos del snc y otros trastornos. |
DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
SE0202430D0 (sv) * | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | New Compounds |
SE0202465D0 (sv) * | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | New compounds |
WO2004029050A1 (en) | 2002-09-25 | 2004-04-08 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof |
JP2006519208A (ja) * | 2003-02-27 | 2006-08-24 | ニューロサーチ、アクティーゼルスカブ | 新規ジアザビシクロアリール誘導体 |
EP1699802A1 (en) * | 2003-12-22 | 2006-09-13 | AstraZeneca AB | Nicotinic acetylcholine receptor ligands |
TW200529860A (en) * | 2003-12-22 | 2005-09-16 | Astrazeneca Ab | Nicotinic acetylcholine receptor ligands |
JP4824578B2 (ja) | 2003-12-22 | 2011-11-30 | メモリー・ファーマシューティカルズ・コーポレイション | インドール類、1,2−ベンズイソオキサゾール類、および1,2−ベンゾイソチアゾール類、ならびにそれらの製造と使用 |
BRPI0506881A (pt) * | 2004-02-04 | 2007-06-26 | Neurosearch As | derivado de arila diazabicìclica, composição farmacêutica, uso de um derivado de arila diazabicìclica, e, método de tratamento, prevenção ou alìvio de uma doença ou distúrbio ou condição de um corpo de animal vivo |
CA2560741C (en) | 2004-03-25 | 2013-08-06 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof |
US7488737B2 (en) | 2004-04-22 | 2009-02-10 | Memory Pharmaceutical Corporation | Indoles, 1H-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof |
JP2007538011A (ja) | 2004-05-07 | 2007-12-27 | メモリー・ファーマシューティカルズ・コーポレイション | 1h−インダゾール、ベンゾチアゾール、1,2−ベンゾイソキサゾール、1,2−ベンゾイソチアゾール、およびクロモン、ならびにそれらの調製および使用 |
EP1802616B1 (en) * | 2004-10-15 | 2011-01-12 | NeuroSearch A/S | Novel azabicyclic aryl derivatives and their medical use |
US7625924B2 (en) | 2004-12-22 | 2009-12-01 | Memory Pharmaceuticals Corporation | Nicotinic alpha-7 receptor ligands and preparation and uses thereof |
US8106066B2 (en) | 2005-09-23 | 2012-01-31 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof |
JP2009526776A (ja) * | 2006-02-14 | 2009-07-23 | ノイロサーチ アクティーゼルスカブ | 新規なジアザビシクロアルカン誘導体及びその医療上の使用 |
JP2007217370A (ja) * | 2006-02-17 | 2007-08-30 | Nard Inst Ltd | ポジトロン断層撮影法および該方法に用いるポジトロン放出化合物 |
EP2029594B1 (en) | 2006-05-23 | 2010-10-20 | NeuroSearch A/S | Novel 1,4-diaza-bicyclo[3.2.2]nonane derivatives and their medical use |
US20100234349A1 (en) | 2006-09-04 | 2010-09-16 | Olsen Gunnar M | Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer |
WO2008119710A1 (en) * | 2007-03-30 | 2008-10-09 | Neurosearch A/S | Two-phase test method for characterizing the effect of a chemical compound on a test animal and maze for carrying out the method |
SA08290475B1 (ar) * | 2007-08-02 | 2013-06-22 | Targacept Inc | (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه |
FR2931677B1 (fr) * | 2008-06-02 | 2010-08-20 | Sanofi Aventis | Association d'un agoniste partiel des recepteurs nicotiniques et d'un inhibiteur d'acetylcholinesterase, composition la contenant et son utilisation dans le traitement des troubles cognitifs |
FR2931823B1 (fr) | 2008-06-02 | 2012-08-17 | Sanofi Aventis | Sel de fumarate du 1,4-diazabicyclo°3.2.2!nonane-carboxylate de 4-bromophenyle, ses formes cristallines, leur preparation et leur utilisation en therapeutique |
EP2540297B1 (en) | 2008-11-19 | 2015-04-08 | Forum Pharmaceuticals Inc. | Treatment of Cognitive Disorders with (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof |
TW201031664A (en) | 2009-01-26 | 2010-09-01 | Targacept Inc | Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide |
RU2011150248A (ru) * | 2009-05-11 | 2013-06-20 | Энвиво Фармасьютикалз, Инк. | Лечение когнитивных расстройств с определенными рецепторами альфа-7 никотиновой кислоты в комбинации с ингибиторами ацетилхолинэстеразы |
CN105837566B (zh) | 2010-05-17 | 2018-02-06 | 富瑞姆制药公司 | (R)‑7‑氯‑N‑(奎宁环‑3‑基)苯并[b]噻吩‑2‑甲酰胺盐酸盐单水合物的晶型 |
EP3673906A1 (en) * | 2011-03-18 | 2020-07-01 | Genzyme Corporation | Glucosylceramide synthase inhibitors |
EP2846796A4 (en) | 2012-05-08 | 2015-10-21 | Forum Pharmaceuticals Inc | METHODS OF MAINTAINING, PROCESSING OR ENHANCING COGNITIVE FUNCTION |
MA37975B2 (fr) | 2012-09-11 | 2021-03-31 | Genzyme Corp | Inhibiteurs de synthase de glucosylcéramide |
IL300090A (en) | 2020-07-24 | 2023-03-01 | Genzyme Corp | Pharmaceutical preparations containing VENGLUSTAT |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0235878A3 (en) * | 1986-01-16 | 1989-06-14 | Beecham Group Plc | Novel compounds |
JP2668670B2 (ja) * | 1995-03-24 | 1997-10-27 | 日本たばこ産業株式会社 | ジアザビシクロ[3.3.1]ノナン誘導体、その中間体及びその医薬用途 |
AU7149798A (en) * | 1997-06-30 | 1999-01-19 | R.J. Reynolds Tobacco Company | 3-pyridyl-1-aza-bicyclo-alkane derivatives for prevention and treatment of cn s disorders |
-
1999
- 1999-03-30 FR FR9903934A patent/FR2791678B1/fr not_active Expired - Fee Related
-
2000
- 2000-03-21 AT AT00911011T patent/ATE232865T1/de active
- 2000-03-21 DK DK00911011T patent/DK1165559T3/da active
- 2000-03-21 WO PCT/FR2000/000697 patent/WO2000058311A1/fr active IP Right Grant
- 2000-03-21 DE DE60001451T patent/DE60001451T2/de not_active Expired - Lifetime
- 2000-03-21 ES ES00911011T patent/ES2192520T3/es not_active Expired - Lifetime
- 2000-03-21 AU AU33018/00A patent/AU3301800A/en not_active Abandoned
- 2000-03-21 JP JP2000608013A patent/JP4500454B2/ja not_active Expired - Fee Related
- 2000-03-21 US US09/937,045 patent/US6987106B1/en not_active Expired - Lifetime
- 2000-03-21 EP EP00911011A patent/EP1165559B1/fr not_active Expired - Lifetime
- 2000-03-28 CO CO00022162A patent/CO5180557A1/es active IP Right Grant
- 2000-03-28 UY UY26082A patent/UY26082A1/es not_active IP Right Cessation
- 2000-03-28 AR ARP000101379A patent/AR023188A1/es active IP Right Grant
- 2000-03-28 TW TW089105707A patent/TWI221843B/zh not_active IP Right Cessation
- 2000-03-30 PE PE2000000274A patent/PE20001600A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ES2192520T3 (es) | 2003-10-16 |
FR2791678A1 (fr) | 2000-10-06 |
FR2791678B1 (fr) | 2001-05-04 |
DE60001451T2 (de) | 2004-01-15 |
JP2002540208A (ja) | 2002-11-26 |
EP1165559B1 (fr) | 2003-02-19 |
CO5180557A1 (es) | 2002-07-30 |
DK1165559T3 (da) | 2003-06-10 |
EP1165559A1 (fr) | 2002-01-02 |
DE60001451D1 (de) | 2003-03-27 |
WO2000058311A1 (fr) | 2000-10-05 |
US6987106B1 (en) | 2006-01-17 |
TWI221843B (en) | 2004-10-11 |
JP4500454B2 (ja) | 2010-07-14 |
AU3301800A (en) | 2000-10-16 |
ATE232865T1 (de) | 2003-03-15 |
UY26082A1 (es) | 2000-10-31 |
AR023188A1 (es) | 2002-09-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20001600A1 (es) | Derivados de 1,4-diazabiciclo (3.3.2) nonan-4-carboxilatos y carboxamidas, su preparacion y su aplicacion en terapeutica | |
TNSN96075A1 (fr) | N-(indole-2-carbonyl) - beta- alaninamides substitues et leurs derives, servant d'agents antidiabetiques | |
DK1140088T3 (da) | Orale methylphenidatformuleringer med reguleret/modificeret frigivelse | |
NO20034230L (no) | 1,2,3,4-tetrahydroisokinolin-derivater som urotensin II reseptor-antagonister | |
PE20020719A1 (es) | Derivados de carbamato de quinuclidina como agentes antimuscarinicos m3 | |
NZ515705A (en) | Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor (PPAR) alpha | |
MY144897A (en) | 2,3,4,9-tetrahydro-1h-carbazole derivatives as crth2 receptor antagonists | |
NO972324L (no) | Orale blandinger inneholdende Ondansetron | |
PE20011114A1 (es) | Decahidro-isoquinolinas | |
ATE275397T1 (de) | Zusammensetzungen, enthaltend blocker des renalen zelltransfers von l-dopa zur behandlung der parkinson-krankheit | |
ATE416767T1 (de) | 5-halo-tryptaminderivate als 5-ht6 und/oder 5-ht7 rezeptorliganden | |
AR029190A1 (es) | Composiciones que contienen derivados del acido hidroxieicosatetraenoico y uso para la manufactura de un medicamento en el tratamiento de trastornos del ojo seco | |
PE20061318A1 (es) | Nuevas combinaciones terapeuticas para el tratamiento o la prevencion de trastornos psicoticos | |
ATE293448T1 (de) | Benzo(d)azepin-derivative als 5-ht6-rezeptor- antagonisten | |
PE20001543A1 (es) | Derivados de piridopiranoacepinas, su preparacion y su aplicacion en terapeutica | |
FI980471A (fi) | 1,3-substituoidut sykloalkeenit ja sykloalkaanit keskushermostoon vaikuttavina aineina | |
BR0008509A (pt) | Composição farmacêutica oral estabilizada contendo iodeto e iodato e método | |
PE20001583A1 (es) | Derivados de la 1-arenosulfonil-2-arilo-pirrolidina y de la piperidina | |
GB8518658D0 (en) | Medicaments | |
BG94282A (bg) | 2,9-дизаместени-4н-пиридо/1,2,-а/пиримидин-4-они | |
ES2160649T3 (es) | Nuevos compuestos lactamicos y procedimientos para su preparacion. | |
AR007352A1 (es) | Derivados sustituidos de bencimidazol, proceso para su preparacion, formulacion farmaceutica que los contiene, y uso de dichos derivados para la manufactura de medicamentos | |
SE0102055D0 (sv) | New Compounds | |
ATE218860T1 (de) | Verwendung von 3,4-diphenylchromanen zur herstellung eines arzneimittels zur behandlung bzw. vorbeugung des prostatakarzinoms | |
DE69808440D1 (de) | Verwendung von (+)mefloquine zur behandlung von malaria |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |