ATE218860T1 - Verwendung von 3,4-diphenylchromanen zur herstellung eines arzneimittels zur behandlung bzw. vorbeugung des prostatakarzinoms - Google Patents
Verwendung von 3,4-diphenylchromanen zur herstellung eines arzneimittels zur behandlung bzw. vorbeugung des prostatakarzinomsInfo
- Publication number
- ATE218860T1 ATE218860T1 AT97900202T AT97900202T ATE218860T1 AT E218860 T1 ATE218860 T1 AT E218860T1 AT 97900202 T AT97900202 T AT 97900202T AT 97900202 T AT97900202 T AT 97900202T AT E218860 T1 ATE218860 T1 AT E218860T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- chromanes
- diphenyl
- prevention
- production
- Prior art date
Links
- 206010060862 Prostate cancer Diseases 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 239000004305 biphenyl Substances 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 201000001514 prostate carcinoma Diseases 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US977696P | 1996-01-11 | 1996-01-11 | |
| US08/678,129 US5883118A (en) | 1996-01-11 | 1996-07-11 | Prostatic carcinoma |
| PCT/DK1997/000010 WO1997025037A1 (en) | 1996-01-11 | 1997-01-09 | Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of prostatic carcinoma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE218860T1 true ATE218860T1 (de) | 2002-06-15 |
Family
ID=26679873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97900202T ATE218860T1 (de) | 1996-01-11 | 1997-01-09 | Verwendung von 3,4-diphenylchromanen zur herstellung eines arzneimittels zur behandlung bzw. vorbeugung des prostatakarzinoms |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5883118A (de) |
| EP (1) | EP0873122B1 (de) |
| JP (1) | JP2000506507A (de) |
| AT (1) | ATE218860T1 (de) |
| AU (1) | AU1367497A (de) |
| CA (1) | CA2241559A1 (de) |
| DE (1) | DE69713273D1 (de) |
| WO (1) | WO1997025037A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6413533B1 (en) * | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
| US6465445B1 (en) | 1998-06-11 | 2002-10-15 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
| US7005428B1 (en) | 1998-06-11 | 2006-02-28 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
| CA2396059A1 (en) * | 1999-12-30 | 2001-07-12 | Signal Pharmaceuticals, Inc. | Compounds and methods for modulation of estrogen receptors |
| JP4976649B2 (ja) * | 2004-09-21 | 2012-07-18 | マーシャル エドワーズ，インク． | 化合物 |
| CN101056868B (zh) * | 2004-09-21 | 2012-05-02 | 马休爱德华兹股份有限公司 | 取代的苯并二氢吡喃衍生物、药物及其在治疗中的应用 |
| US8080675B2 (en) | 2004-09-21 | 2011-12-20 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| CN106038572A (zh) | 2004-10-20 | 2016-10-26 | 恩多研究公司 | 性甾体前体单独或与选择性雌激素受体调节剂联合用于预防和治疗绝经后女性的性功能障碍 |
| US8268806B2 (en) | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
| MX2010004195A (es) | 2007-10-16 | 2010-06-02 | Repros Therapeutics Inc | Trans-clomifeno para el sindrome metabolico. |
| US20100317635A1 (en) | 2009-06-16 | 2010-12-16 | Endorecherche, Inc. | Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators |
| SG186333A1 (en) | 2010-06-16 | 2013-01-30 | Endorech Inc | Methods of treating or preventing estrogen-related diseases |
| WO2012061409A1 (en) | 2010-11-01 | 2012-05-10 | Marshall Edwards, Inc. | Isoflavonoid compounds and methods for the treatment of cancer |
| MX2014009322A (es) | 2012-02-29 | 2014-11-10 | Repros Therapeutics Inc | Terapia de combinacion para el tratamiento de la deficiencia androgenica. |
| ES2643407T3 (es) | 2014-02-07 | 2017-11-22 | Novogen Ltd. | Compuestos de benzopirano funcionalizados y uso de los mismos |
| US9744177B2 (en) | 2014-03-10 | 2017-08-29 | Endorecherche, Inc. | Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM |
| PT3253208T (pt) | 2015-02-02 | 2021-06-17 | The Spanish National Cancer Res Centre | Terapêuticas de combinação para utilização no tratamento do cancro da mama |
| US11633382B2 (en) | 2015-11-10 | 2023-04-25 | Paracrine Therapeutics Ab | Treatment of ER-negative breast cancer with an PDGF-CC inhibitor and anti-estrogen |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5280040A (en) * | 1993-03-11 | 1994-01-18 | Zymogenetics, Inc. | Methods for reducing bone loss using centchroman derivatives |
| US5407955A (en) * | 1994-02-18 | 1995-04-18 | Eli Lilly And Company | Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease |
-
1996
- 1996-07-11 US US08/678,129 patent/US5883118A/en not_active Expired - Fee Related
-
1997
- 1997-01-09 AU AU13674/97A patent/AU1367497A/en not_active Abandoned
- 1997-01-09 CA CA002241559A patent/CA2241559A1/en not_active Abandoned
- 1997-01-09 DE DE69713273T patent/DE69713273D1/de not_active Expired - Lifetime
- 1997-01-09 EP EP97900202A patent/EP0873122B1/de not_active Expired - Lifetime
- 1997-01-09 AT AT97900202T patent/ATE218860T1/de not_active IP Right Cessation
- 1997-01-09 JP JP9524770A patent/JP2000506507A/ja active Pending
- 1997-01-09 WO PCT/DK1997/000010 patent/WO1997025037A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US5883118A (en) | 1999-03-16 |
| EP0873122A1 (de) | 1998-10-28 |
| DE69713273D1 (de) | 2002-07-18 |
| CA2241559A1 (en) | 1997-07-17 |
| JP2000506507A (ja) | 2000-05-30 |
| AU1367497A (en) | 1997-08-01 |
| WO1997025037A1 (en) | 1997-07-17 |
| EP0873122B1 (de) | 2002-06-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |