MX9705219A - Uso de 3,4-difenil-cromanos para la fabricacion de una composicion farmaceutica para el tratamiento o profilaxis de desordenes ginecologicos. - Google Patents

Uso de 3,4-difenil-cromanos para la fabricacion de una composicion farmaceutica para el tratamiento o profilaxis de desordenes ginecologicos.

Info

Publication number
MX9705219A
MX9705219A MX9705219A MX9705219A MX9705219A MX 9705219 A MX9705219 A MX 9705219A MX 9705219 A MX9705219 A MX 9705219A MX 9705219 A MX9705219 A MX 9705219A MX 9705219 A MX9705219 A MX 9705219A
Authority
MX
Mexico
Prior art keywords
prophylaxis
manufacture
treatment
pharmaceutical composition
gynaecological disorders
Prior art date
Application number
MX9705219A
Other languages
English (en)
Inventor
Martin William Edwards
James Robertson Piggott
Virender Mohan Lobroo
Ved Prakash Kamboj
Suprabhat Ray
Niels Korsgaard
Michael Shalmi
Birgitte Hjort Guldhammer
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of MX9705219A publication Critical patent/MX9705219A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

La presente invencion proporciona los nuevos usos de compuestos de la formula general I en donde R1, R4 y R5 son individualmente hidrogeno, hidroxilo, halogeno, trifluorometilo, alquilo inferior, alcoxi inferior o (amino terciario) (alcoxi inferior); y R2 y R3 son individualmente hidrogeno o alquilo inferior, o como una sal farmacéuticamente aceptable de los mismos, en combinacion con un portador farmacéuticamente aceptable, para la fabricacion de una composicion farmacéutica para el tratamiento o profilaxis de desordenes ginecologicos, incluyendo endometriosis, sangrados disfuncionales, cáncer endometrial, síndrome de ovario poliquístico y sangrado anovulatorio, y además para el adelgazamiento del endometrio.
MX9705219A 1995-01-13 1996-01-10 Uso de 3,4-difenil-cromanos para la fabricacion de una composicion farmaceutica para el tratamiento o profilaxis de desordenes ginecologicos. MX9705219A (es)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
DK4695 1995-01-13
DK4895 1995-01-13
DK4595 1995-01-13
DK4795 1995-01-13
DK4495 1995-01-13
DK77095 1995-06-30
DK76995 1995-06-30
DK77295 1995-06-30
DK76895 1995-06-30
DK77195 1995-06-30
PCT/DK1996/000015 WO1996021444A1 (en) 1995-01-13 1996-01-10 Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of gynaecological disorders

Publications (1)

Publication Number Publication Date
MX9705219A true MX9705219A (es) 1997-10-31

Family

ID=27579214

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9705219A MX9705219A (es) 1995-01-13 1996-01-10 Uso de 3,4-difenil-cromanos para la fabricacion de una composicion farmaceutica para el tratamiento o profilaxis de desordenes ginecologicos.

Country Status (11)

Country Link
EP (1) EP0804190A1 (es)
JP (1) JPH10511962A (es)
CN (1) CN1168096A (es)
AU (1) AU693628B2 (es)
CA (1) CA2208861A1 (es)
CZ (1) CZ212297A3 (es)
HU (1) HUP9702244A3 (es)
IL (1) IL116746A0 (es)
MX (1) MX9705219A (es)
NO (1) NO973243L (es)
WO (1) WO1996021444A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69718500T2 (de) * 1996-10-28 2003-11-27 Novo Nordisk As (-)-enantiomere von cis-3,4-chromanderivaten zur vorbeugung oder behandlungvon oestrogenbezogenen krankheiten oder syndromen
US6316494B1 (en) 1996-10-28 2001-11-13 Novo Nordisk A/S cis3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
IL129618A0 (en) * 1996-10-28 2000-02-29 Novo Nordisk As Novel CIS-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
WO1998018772A1 (en) * 1996-10-28 1998-05-07 Novo Nordisk A/S NOVEL cis-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES
US5985306A (en) * 1996-10-28 1999-11-16 Novo Nordisk A/S (+)-enantiomers of cis-3,4-chroman derivatives useful in prevention or treatment of estrogen diseases or syndromes
IL129616A0 (en) * 1996-10-28 2000-02-29 Novo Nordisk As Novel CIS-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
EP0937058A1 (en) * 1996-10-28 1999-08-25 Novo Nordisk A/S NOVEL $i(CIS)-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES
IL129617A0 (en) * 1996-10-28 2000-02-29 Novo Nordisk As Novel CIS-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US5958967A (en) * 1996-10-28 1999-09-28 Novo Nordisk A/S Cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
JP2001502706A (ja) * 1996-10-28 2001-02-27 ノボ ノルディスク アクティーゼルスカブ エストロゲン関連病あるいは症候群の予防または治療に有用な新規トランス―３，４クロマン誘導体
ZA979644B (en) * 1996-10-28 1998-04-28 Novo Nordisk As Heterocyclic compounds, compositions and uses.
US5994390A (en) * 1996-10-28 1999-11-30 Novo Nordisk Trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US6043269A (en) * 1996-10-28 2000-03-28 Novo Nordisk A/S cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
IL129627A0 (en) * 1996-10-28 2000-02-29 Novo Nordisk As Novel CIS-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US5919817A (en) * 1996-10-28 1999-07-06 Novo Nordisk A/S Cis-3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US7214706B2 (en) 2000-03-01 2007-05-08 Akzo Nobel N.V. Chroman derivatives as estrogenic compounds
WO2006032085A1 (en) 2004-09-21 2006-03-30 Novogen Research Pty Ltd Substituted chroman derivatives, medicaments and use in therapy
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
WO2012061413A2 (en) 2010-11-01 2012-05-10 Marshall Edwards, Inc. Isoflavonoid compositions and methods for the treatment of cancer
ES2643407T3 (es) 2014-02-07 2017-11-22 Novogen Ltd. Compuestos de benzopirano funcionalizados y uso de los mismos
ES2877712T3 (es) 2015-02-02 2021-11-17 Mei Pharma Inc Terapias combinadas para su uso en el tratamiento del cáncer de mama

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5407955A (en) * 1994-02-18 1995-04-18 Eli Lilly And Company Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease

Also Published As

Publication number Publication date
CA2208861A1 (en) 1996-07-18
IL116746A0 (en) 1996-05-14
JPH10511962A (ja) 1998-11-17
WO1996021444A1 (en) 1996-07-18
NO973243D0 (no) 1997-07-11
NO973243L (no) 1997-07-11
AU693628B2 (en) 1998-07-02
HUP9877967A2 (en) 1998-12-28
EP0804190A1 (en) 1997-11-05
CZ212297A3 (en) 1997-11-12
AU4329396A (en) 1996-07-31
CN1168096A (zh) 1997-12-17
HUP9702244A3 (en) 1999-12-28

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