PE20001296A1 - El uso de una combinacion de tipranavir y ritonavir para mejorar la farmacocinetica del tipranavir - Google Patents
El uso de una combinacion de tipranavir y ritonavir para mejorar la farmacocinetica del tipranavirInfo
- Publication number
- PE20001296A1 PE20001296A1 PE1999001100A PE00110099A PE20001296A1 PE 20001296 A1 PE20001296 A1 PE 20001296A1 PE 1999001100 A PE1999001100 A PE 1999001100A PE 00110099 A PE00110099 A PE 00110099A PE 20001296 A1 PE20001296 A1 PE 20001296A1
- Authority
- PE
- Peru
- Prior art keywords
- tipranavir
- ritonavir
- combination
- pharmacokinetics
- amino
- Prior art date
Links
- SUJUHGSWHZTSEU-UHFFFAOYSA-N Tipranavir Natural products C1C(O)=C(C(CC)C=2C=C(NS(=O)(=O)C=3N=CC(=CC=3)C(F)(F)F)C=CC=2)C(=O)OC1(CCC)CCC1=CC=CC=C1 SUJUHGSWHZTSEU-UHFFFAOYSA-N 0.000 title 2
- 229960000838 tipranavir Drugs 0.000 title 2
- SUJUHGSWHZTSEU-FYBSXPHGSA-N tipranavir Chemical compound C([C@@]1(CCC)OC(=O)C([C@H](CC)C=2C=C(NS(=O)(=O)C=3N=CC(=CC=3)C(F)(F)F)C=CC=2)=C(O)C1)CC1=CC=CC=C1 SUJUHGSWHZTSEU-FYBSXPHGSA-N 0.000 title 2
- NCDNCNXCDXHOMX-UHFFFAOYSA-N Ritonavir Natural products C=1C=CC=CC=1CC(NC(=O)OCC=1SC=NC=1)C(O)CC(CC=1C=CC=CC=1)NC(=O)C(C(C)C)NC(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-UHFFFAOYSA-N 0.000 title 1
- 229960000311 ritonavir Drugs 0.000 title 1
- NCDNCNXCDXHOMX-XGKFQTDJSA-N ritonavir Chemical compound N([C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC=1C=CC=CC=1)NC(=O)OCC=1SC=NC=1)CC=1C=CC=CC=1)C(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-XGKFQTDJSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10696398P | 1998-11-04 | 1998-11-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20001296A1 true PE20001296A1 (es) | 2000-11-23 |
Family
ID=22314155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999001100A PE20001296A1 (es) | 1998-11-04 | 1999-11-03 | El uso de una combinacion de tipranavir y ritonavir para mejorar la farmacocinetica del tipranavir |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6147095A (enExample) |
| EP (1) | EP1126847A1 (enExample) |
| JP (1) | JP2002528502A (enExample) |
| CN (1) | CN1154491C (enExample) |
| AU (1) | AU762349B2 (enExample) |
| BR (1) | BR9914940A (enExample) |
| CA (1) | CA2346131C (enExample) |
| CO (1) | CO5160321A1 (enExample) |
| HK (1) | HK1040625B (enExample) |
| MY (1) | MY118526A (enExample) |
| PE (1) | PE20001296A1 (enExample) |
| TW (1) | TW580387B (enExample) |
| WO (1) | WO2000025784A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9815567D0 (en) * | 1998-07-18 | 1998-09-16 | Glaxo Group Ltd | Antiviral compound |
| BR0114969A (pt) * | 2000-10-31 | 2003-12-09 | Boehringer Ingelheim Pharma | Formulações de emulsificação própria de dosagem oral de inibidores de piranona protease |
| US6500963B2 (en) | 2001-02-22 | 2002-12-31 | Boehringer Ingelheim Pharma Kg | Process for preparing optically active dihydropyrones |
| DE10108470A1 (de) * | 2001-02-22 | 2002-09-05 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung optisch aktiver Dihydropyrone |
| US20030180279A1 (en) * | 2002-03-19 | 2003-09-25 | Tibor Sipos | Composition and method to prevent or reduce diarrhea and steatorrhea in HIV patients |
| US20040197321A1 (en) * | 2002-03-19 | 2004-10-07 | Tibor Sipos | Composition and method to prevent or reduce diarrhea and steatorrhea in HIV patients |
| WO2004060370A1 (en) * | 2002-12-16 | 2004-07-22 | Boehringer Ingelheim Pharmaceuticals, Inc. | Treatment of hiv infection through combined administration of tipranavir and capravirine |
| US20040152625A1 (en) * | 2002-12-16 | 2004-08-05 | Boehringer Ingelheim International Gmbh | Method for improving the pharmacokinetics of an NNRTI |
| WO2004087139A1 (en) * | 2003-03-27 | 2004-10-14 | Boehringer Ingelheim International Gmbh | Antiviral combination of tipranavir and a further antiretroviral compound |
| AR045841A1 (es) * | 2004-09-28 | 2005-11-16 | Richmond Sa Com Ind Y Financie | Una composicion farmaceutica solida que comprende al tiazolil metil ester del acido [5s-(5r*, 8r*, 10r*,11r*)] -10- hidroxi-2- metil-5-(1-metiletil)-1-[2-(1-metiletil)-4-tiazolil]-3,6-dioxo-8,11-bis(fenilmetil)-2,4,7,12- tetraazatridecan-13-oico y un procedimiento para prepararla. |
| EP1812069A2 (en) * | 2004-11-08 | 2007-08-01 | Boehringer Ingelheim International GmbH | Method for treating hiv infection through co-administration of tipranavir and etravirine |
| CA2585576A1 (en) * | 2004-11-16 | 2006-05-26 | Boehringer Ingelheim International Gmbh | Method for treating hiv infection through co-administration of tipranavir and darunavir |
| EP1814549A2 (en) * | 2004-11-19 | 2007-08-08 | Boehringer Ingelheim International GmbH | Method for treating hiv infection through co-administration of tipranavir and uk-427, 857 |
| WO2006055754A1 (en) * | 2004-11-19 | 2006-05-26 | Boehringer Ingelheim International Gmbh | Method for treating hiv infection through co-administration of tipranavir and reverset |
| JP2008521896A (ja) * | 2004-12-01 | 2008-06-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | チプラナビル及びgw695634を共に投与することを含むhiv感染症の治療方法 |
| EP1819333A1 (en) * | 2004-12-01 | 2007-08-22 | Boehringer Ingelheim International Gmbh | Method for treating hiv infection through co-administration of tipranavir and gw873140 |
| JP2008521897A (ja) * | 2004-12-01 | 2008-06-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | チプラナビル及びsch−417690を共に投与することを含むhiv感染症の治療方法 |
| US8598364B2 (en) | 2007-03-12 | 2013-12-03 | Nektar Therapeutics | Oligomer-protease inhibitor conjugates |
| EP2262538B1 (en) * | 2008-03-12 | 2014-12-10 | Nektar Therapeutics | Oligomer-amino acid conjugate |
| US20100021505A1 (en) * | 2008-07-28 | 2010-01-28 | Tibor Sipos | Composition and method to prevent or reduce diarrhea and steatorrhea in HIV patients |
| US20120108501A1 (en) | 2009-06-12 | 2012-05-03 | Nektar Therapeutics | Protease Inhibitors |
| AU2011234013A1 (en) * | 2010-04-02 | 2012-11-15 | Phivco-1 Llc | Combination therapy comprising a CCR5 antagonist, a HIV-1 protease inhibitor and a pharmacokinetic enhancer |
| CN104160274A (zh) * | 2011-05-30 | 2014-11-19 | 奥德特里克公司 | 通过照护点药物动力学曲线分析进行治疗药物监测和投配的方法与组合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5608085A (en) * | 1995-02-27 | 1997-03-04 | The University Of Tennessee Research Corporation | Synthesis of optically active calanolides A and B and enantiomers and related compounds |
| US6037157A (en) * | 1995-06-29 | 2000-03-14 | Abbott Laboratories | Method for improving pharmacokinetics |
| US5932570A (en) * | 1996-11-08 | 1999-08-03 | Dupont Pharmaceuticals Company | 1-(3-aminoindazol-5-yl)-3-phenylmethyl-cyclic ureas useful as HIV protease inhibitors |
| ZA9710071B (en) * | 1996-11-21 | 1998-05-25 | Abbott Lab | Pharmaceutical composition. |
-
1999
- 1999-10-29 AU AU14404/00A patent/AU762349B2/en not_active Expired
- 1999-10-29 EP EP99971319A patent/EP1126847A1/en active Pending
- 1999-10-29 US US09/430,742 patent/US6147095A/en not_active Expired - Lifetime
- 1999-10-29 CA CA2346131A patent/CA2346131C/en not_active Expired - Lifetime
- 1999-10-29 CN CNB998123587A patent/CN1154491C/zh not_active Expired - Lifetime
- 1999-10-29 HK HK02102194.8A patent/HK1040625B/zh not_active IP Right Cessation
- 1999-10-29 BR BR9914940-0A patent/BR9914940A/pt not_active Application Discontinuation
- 1999-10-29 WO PCT/US1999/021469 patent/WO2000025784A1/en not_active Ceased
- 1999-10-29 JP JP2000579225A patent/JP2002528502A/ja active Pending
- 1999-11-03 PE PE1999001100A patent/PE20001296A1/es not_active Application Discontinuation
- 1999-11-04 TW TW088119229A patent/TW580387B/zh not_active IP Right Cessation
- 1999-11-04 MY MYPI99004794A patent/MY118526A/en unknown
- 1999-11-04 CO CO99069669A patent/CO5160321A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1040625A1 (en) | 2002-06-21 |
| CO5160321A1 (es) | 2002-05-30 |
| US6147095A (en) | 2000-11-14 |
| CN1154491C (zh) | 2004-06-23 |
| BR9914940A (pt) | 2001-07-10 |
| AU1440400A (en) | 2000-05-22 |
| AU762349B2 (en) | 2003-06-26 |
| CA2346131A1 (en) | 2000-05-11 |
| TW580387B (en) | 2004-03-21 |
| HK1040625B (zh) | 2005-04-01 |
| CA2346131C (en) | 2013-01-15 |
| CN1324237A (zh) | 2001-11-28 |
| WO2000025784A1 (en) | 2000-05-11 |
| EP1126847A1 (en) | 2001-08-29 |
| JP2002528502A (ja) | 2002-09-03 |
| MY118526A (en) | 2004-11-30 |
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Legal Events
| Date | Code | Title | Description |
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| FC | Refusal |