PE20000020A1 - Composiciones para el tratamiento del sida e infeccion del vih - Google Patents
Composiciones para el tratamiento del sida e infeccion del vihInfo
- Publication number
- PE20000020A1 PE20000020A1 PE1998001094A PE00109498A PE20000020A1 PE 20000020 A1 PE20000020 A1 PE 20000020A1 PE 1998001094 A PE1998001094 A PE 1998001094A PE 00109498 A PE00109498 A PE 00109498A PE 20000020 A1 PE20000020 A1 PE 20000020A1
- Authority
- PE
- Peru
- Prior art keywords
- hydroxy
- hiv infection
- aids
- nucleosid
- refers
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A UNA COMPOSICION QUE COMPRENDE a)UN INHIBIDOR DE PROTEASA DE VIH DE FORMULA A, N-(2(R)-HIDROXI-1(S)-INDALIL)-2(R)-FENILMETIL-4-(S)-HIDROXI-5-(1-(4-(2-BENZO(b)FURANILMETIL)-2(S)-N`-(t-BUTILCARBOXAMIDO)-PIPERAZINIL))-PENTANOAMIDA; b)UNO O MAS AGENTES ANTIRETROVIRALES INHIBIDORES DE TRANSCRIPTASA INVERSA NUCLEOSIDOS O NO NUCLEOSIDOS COMO ZIDOVUDINA, LAMIVUDINA, STAVUDINA, RITONAVIR, NELFINAVIR, ABACAVIR, INDINAVIR, DELAVIRDINA, (-)-6-CLORO-4-CICLOPROPILETINIL-4-TRIFLUOROMETIL-1,4-DIHIDRO-2H-3,1-BENZOXACIN-2-ONA, 4-AMINO-N-((2,3S)-2-HIDROXI-4-FENIL-3-((S)-TETRAHIDROFURANO-3-ILOXICARBONILAMINO)-BUTIL)-N-ISOBUTIL-BENCENOSULFONAMIDA; ESTAN PRESENTES EN UNA PROPORCION DE 2:1 A 1:2. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION. LA COMPOSICION PUEDE SER UTIL PARA TRATAR O PREVENIR LA INFECCION POR VIH, TRATAR EL SIDA
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6542197P | 1997-11-13 | 1997-11-13 | |
GBGB9807938.7A GB9807938D0 (en) | 1998-04-15 | 1998-04-15 | Combination therapy for the treatment of AIDS |
US9094098P | 1998-06-26 | 1998-06-26 | |
GBGB9819590.2A GB9819590D0 (en) | 1998-09-08 | 1998-09-08 | Combination therapy for the treatment of aids |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20000020A1 true PE20000020A1 (es) | 2000-01-27 |
Family
ID=27451773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1998001094A PE20000020A1 (es) | 1997-11-13 | 1998-11-12 | Composiciones para el tratamiento del sida e infeccion del vih |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP1044000B1 (es) |
JP (1) | JP2001522889A (es) |
KR (1) | KR20010032055A (es) |
CN (1) | CN1285747A (es) |
AR (1) | AR013758A1 (es) |
AT (1) | ATE218866T1 (es) |
AU (1) | AU749795B2 (es) |
BG (1) | BG104507A (es) |
BR (1) | BR9814146A (es) |
CA (1) | CA2309164A1 (es) |
CO (1) | CO4970782A1 (es) |
DE (1) | DE69806062T2 (es) |
EA (1) | EA200000513A1 (es) |
ES (1) | ES2177103T3 (es) |
HU (1) | HUP0100365A3 (es) |
ID (1) | ID24922A (es) |
IL (1) | IL135994A0 (es) |
IS (1) | IS5481A (es) |
NO (1) | NO20002481L (es) |
PE (1) | PE20000020A1 (es) |
PL (1) | PL340430A1 (es) |
SK (1) | SK6842000A3 (es) |
TR (1) | TR200001938T2 (es) |
WO (1) | WO1999025352A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9820417D0 (en) * | 1998-09-18 | 1998-11-11 | Glaxo Group Ltd | Antiviral combinations |
WO2003011221A2 (en) | 2001-07-30 | 2003-02-13 | University Of Southern California | PREPARATION AND USE OF α-KETO PHOSPHONATES |
KR20080032014A (ko) | 2003-01-14 | 2008-04-11 | 길리애드 사이언시즈, 인코포레이티드 | 복합 항바이러스 치료를 위한 조성물 및 방법 |
GB2400553A (en) * | 2003-04-14 | 2004-10-20 | Cipla Ltd | Antiviral pharmaceutical combination of lamivudine, stavudine and efavirenz, or derivatives thereof |
TWI375560B (en) | 2005-06-13 | 2012-11-01 | Gilead Sciences Inc | Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same |
TWI471145B (zh) | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2174921T3 (es) * | 1993-12-15 | 2002-11-16 | Merck & Co Inc | Inhibidores de la proteasa del vih. |
-
1998
- 1998-11-11 CO CO98066470A patent/CO4970782A1/es unknown
- 1998-11-12 AR ARP980105720A patent/AR013758A1/es unknown
- 1998-11-12 HU HU0100365A patent/HUP0100365A3/hu unknown
- 1998-11-12 ID IDW20000895A patent/ID24922A/id unknown
- 1998-11-12 BR BR9814146-5A patent/BR9814146A/pt not_active Application Discontinuation
- 1998-11-12 KR KR1020007005176A patent/KR20010032055A/ko not_active Application Discontinuation
- 1998-11-12 ES ES98959424T patent/ES2177103T3/es not_active Expired - Lifetime
- 1998-11-12 JP JP2000520785A patent/JP2001522889A/ja not_active Withdrawn
- 1998-11-12 EP EP98959424A patent/EP1044000B1/en not_active Expired - Lifetime
- 1998-11-12 CN CN98813077A patent/CN1285747A/zh active Pending
- 1998-11-12 WO PCT/US1998/024097 patent/WO1999025352A1/en not_active Application Discontinuation
- 1998-11-12 AT AT98959424T patent/ATE218866T1/de not_active IP Right Cessation
- 1998-11-12 CA CA002309164A patent/CA2309164A1/en not_active Abandoned
- 1998-11-12 PL PL98340430A patent/PL340430A1/xx unknown
- 1998-11-12 TR TR2000/01938T patent/TR200001938T2/xx unknown
- 1998-11-12 PE PE1998001094A patent/PE20000020A1/es not_active Application Discontinuation
- 1998-11-12 IL IL13599498A patent/IL135994A0/xx unknown
- 1998-11-12 DE DE69806062T patent/DE69806062T2/de not_active Expired - Fee Related
- 1998-11-12 EA EA200000513A patent/EA200000513A1/ru unknown
- 1998-11-12 AU AU15225/99A patent/AU749795B2/en not_active Ceased
- 1998-11-12 SK SK684-2000A patent/SK6842000A3/sk unknown
-
2000
- 2000-05-09 IS IS5481A patent/IS5481A/is unknown
- 2000-05-12 NO NO20002481A patent/NO20002481L/no not_active Application Discontinuation
- 2000-06-05 BG BG104507A patent/BG104507A/bg unknown
Also Published As
Publication number | Publication date |
---|---|
ID24922A (id) | 2000-08-31 |
IS5481A (is) | 2000-05-09 |
EA200000513A1 (ru) | 2000-10-30 |
BR9814146A (pt) | 2000-10-03 |
NO20002481D0 (no) | 2000-05-12 |
DE69806062T2 (de) | 2003-03-20 |
AU749795B2 (en) | 2002-07-04 |
AU1522599A (en) | 1999-06-07 |
CO4970782A1 (es) | 2000-11-07 |
SK6842000A3 (en) | 2000-12-11 |
JP2001522889A (ja) | 2001-11-20 |
IL135994A0 (en) | 2001-05-20 |
EP1044000A1 (en) | 2000-10-18 |
HUP0100365A3 (en) | 2002-06-28 |
ATE218866T1 (de) | 2002-06-15 |
WO1999025352A1 (en) | 1999-05-27 |
PL340430A1 (en) | 2001-02-12 |
DE69806062D1 (de) | 2002-07-18 |
BG104507A (bg) | 2001-03-30 |
TR200001938T2 (tr) | 2001-07-23 |
AR013758A1 (es) | 2001-01-10 |
CA2309164A1 (en) | 1999-05-27 |
HUP0100365A2 (hu) | 2002-05-29 |
NO20002481L (no) | 2000-07-12 |
KR20010032055A (ko) | 2001-04-16 |
CN1285747A (zh) | 2001-02-28 |
EP1044000B1 (en) | 2002-06-12 |
ES2177103T3 (es) | 2002-12-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20110236A1 (es) | Proteccion y mejoramiento de celulas, tejidos y organos que responden a la eritropoyetina | |
PT1318791E (pt) | Composicao farmaceutica semi-solida de isotretinoina | |
BRPI0113162B8 (pt) | compostos ariloxialquilaminas nao-imidazólicos e composição farmacêutica compreendendo os referidos compostos | |
BR0113286A (pt) | Pirazóis substituìdos | |
BR9807098A (pt) | Antagonistas de endotelina: n[[2'-[[(4,5-dimetil-3-isoxazolil)amino]sulfonil]-4-(2-oxa zolil)[1,1'-bi-fenil]-2-il]-n,3,3-trimetilbutanamida e n-(4,5-dimetil-3-isoxazolil)-2'-[(3,3-dimetil-2-oxo-1-pirro lidinil) metil]-4'-2-oxazolil)[1,1' -bifenil]-2-sulfonamida e sais dos mesmos | |
BR0213207A (pt) | remodelagem e glicoconjugação de peptìdeos | |
MX9403380A (es) | Inhibidores de proteasa de vih utiles para el tratamiento de sida. | |
PA8513601A1 (es) | Composiciones farmaceuticas de inhibidores de la glucogenofosforilasa | |
BR0015056A (pt) | Composto, uso de um composto, composição farmacêutica, método de tratamento de infecções por hiv e kit farmacêutico | |
ES2178036T3 (es) | Derivados de ciclosporina, su preparacion y las composiciones farmaceuticas que le contienen. | |
BRPI0510870A (pt) | composição resistente ao impacto | |
BR0000654A (pt) | Preparação de composição de borracha vulcanizada com peróxido e artigos tendo ela pelo menos como um dos seus componentes | |
CO5440227A1 (es) | Composicion antihelmitica e inyectable mejorada de crecimiento | |
CY1111567T1 (el) | Ενδιαμεσα διβενζο (b,f) αζεπινης | |
PE20000020A1 (es) | Composiciones para el tratamiento del sida e infeccion del vih | |
ES2174921T3 (es) | Inhibidores de la proteasa del vih. | |
DE69732709D1 (de) | Expressionsblockierung von virulenten faktoren in s. aureus | |
CO5280222A1 (es) | Composicion farmaceutica que comprende pemetrexed | |
ES2179093T3 (es) | Inhibidores de la prolilendopeptidasa. | |
DE60139553D1 (de) | Zusammensetzungen, testsätze und methoden zur identifizierung und modulation von typ i diabetes | |
ES2069536T3 (es) | Analogos del activador del plasminogeno tisular que tienen dominios modificados del factor de crecimiento. | |
BR0114082A (pt) | Compostos, composições farmacêuticas, uso de um ou mais compostos, e, processo para a fabricação de composições farmacêuticas | |
ES2127349T3 (es) | Aditivos polimeros mejoradores del flujo. | |
EA200100711A1 (ru) | Аналоги нуклеозида (варианты) и их применение, комбинация и способ лечения вирусных инфекций, фармацевтическая композиция | |
DK0506769T3 (da) | Farmaceutisk præparat til behandling eller forebyggelse af retrovirus-infektioner |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |