ES2177103T3 - Terapia de combinacion para el tratamiento del sida. - Google Patents
Terapia de combinacion para el tratamiento del sida.Info
- Publication number
- ES2177103T3 ES2177103T3 ES98959424T ES98959424T ES2177103T3 ES 2177103 T3 ES2177103 T3 ES 2177103T3 ES 98959424 T ES98959424 T ES 98959424T ES 98959424 T ES98959424 T ES 98959424T ES 2177103 T3 ES2177103 T3 ES 2177103T3
- Authority
- ES
- Spain
- Prior art keywords
- aids
- treatment
- combination therapy
- pharmaceutically acceptable
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Abstract
Una composición que comprende (a) el Compuesto A de la fórmula o una sal o un éster farmacéuticamente aceptable del mismo y (b) un compuesto seleccionado entre Indinavir, Ritonavir, Nelfinavir, Delavirdina, 141-W94 y las sales y los ésteres farmacéuticamente aceptables de los mismos.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6542197P | 1997-11-13 | 1997-11-13 | |
GBGB9807938.7A GB9807938D0 (en) | 1998-04-15 | 1998-04-15 | Combination therapy for the treatment of AIDS |
US9094098P | 1998-06-26 | 1998-06-26 | |
GBGB9819590.2A GB9819590D0 (en) | 1998-09-08 | 1998-09-08 | Combination therapy for the treatment of aids |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2177103T3 true ES2177103T3 (es) | 2002-12-01 |
Family
ID=27451773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98959424T Expired - Lifetime ES2177103T3 (es) | 1997-11-13 | 1998-11-12 | Terapia de combinacion para el tratamiento del sida. |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP1044000B1 (es) |
JP (1) | JP2001522889A (es) |
KR (1) | KR20010032055A (es) |
CN (1) | CN1285747A (es) |
AR (1) | AR013758A1 (es) |
AT (1) | ATE218866T1 (es) |
AU (1) | AU749795B2 (es) |
BG (1) | BG104507A (es) |
BR (1) | BR9814146A (es) |
CA (1) | CA2309164A1 (es) |
CO (1) | CO4970782A1 (es) |
DE (1) | DE69806062T2 (es) |
EA (1) | EA200000513A1 (es) |
ES (1) | ES2177103T3 (es) |
HU (1) | HUP0100365A3 (es) |
ID (1) | ID24922A (es) |
IL (1) | IL135994A0 (es) |
IS (1) | IS5481A (es) |
NO (1) | NO20002481L (es) |
PE (1) | PE20000020A1 (es) |
PL (1) | PL340430A1 (es) |
SK (1) | SK6842000A3 (es) |
TR (1) | TR200001938T2 (es) |
WO (1) | WO1999025352A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9820417D0 (en) * | 1998-09-18 | 1998-11-11 | Glaxo Group Ltd | Antiviral combinations |
AU2002355739A1 (en) | 2001-07-30 | 2003-02-17 | University Of Southern California | Preparation and use of alpha-keto phosphonates |
EP1923063A3 (en) * | 2003-01-14 | 2009-04-08 | Gilead Sciences, Inc. | Compositions and methods for combination antiviral therapy |
GB2400553A (en) * | 2003-04-14 | 2004-10-20 | Cipla Ltd | Antiviral pharmaceutical combination of lamivudine, stavudine and efavirenz, or derivatives thereof |
TWI375560B (en) | 2005-06-13 | 2012-11-01 | Gilead Sciences Inc | Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same |
TWI471145B (zh) | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUT74681A (en) * | 1993-12-15 | 1997-01-28 | Merck & Co Inc | N-(2-hydroxy-1-indenyl)-2-phenylmethyl-4-hydroxy-5-(2-carboxamido-piperazinyl)-pentaneamide derivatives of hiv protease inhibitor activity and phrmaceutical compositions contining them |
-
1998
- 1998-11-11 CO CO98066470A patent/CO4970782A1/es unknown
- 1998-11-12 KR KR1020007005176A patent/KR20010032055A/ko not_active Application Discontinuation
- 1998-11-12 AU AU15225/99A patent/AU749795B2/en not_active Ceased
- 1998-11-12 BR BR9814146-5A patent/BR9814146A/pt not_active Application Discontinuation
- 1998-11-12 PE PE1998001094A patent/PE20000020A1/es not_active Application Discontinuation
- 1998-11-12 JP JP2000520785A patent/JP2001522889A/ja not_active Withdrawn
- 1998-11-12 ID IDW20000895A patent/ID24922A/id unknown
- 1998-11-12 AT AT98959424T patent/ATE218866T1/de not_active IP Right Cessation
- 1998-11-12 TR TR2000/01938T patent/TR200001938T2/xx unknown
- 1998-11-12 DE DE69806062T patent/DE69806062T2/de not_active Expired - Fee Related
- 1998-11-12 CN CN98813077A patent/CN1285747A/zh active Pending
- 1998-11-12 SK SK684-2000A patent/SK6842000A3/sk unknown
- 1998-11-12 HU HU0100365A patent/HUP0100365A3/hu unknown
- 1998-11-12 WO PCT/US1998/024097 patent/WO1999025352A1/en not_active Application Discontinuation
- 1998-11-12 IL IL13599498A patent/IL135994A0/xx unknown
- 1998-11-12 PL PL98340430A patent/PL340430A1/xx unknown
- 1998-11-12 ES ES98959424T patent/ES2177103T3/es not_active Expired - Lifetime
- 1998-11-12 EA EA200000513A patent/EA200000513A1/ru unknown
- 1998-11-12 AR ARP980105720A patent/AR013758A1/es unknown
- 1998-11-12 EP EP98959424A patent/EP1044000B1/en not_active Expired - Lifetime
- 1998-11-12 CA CA002309164A patent/CA2309164A1/en not_active Abandoned
-
2000
- 2000-05-09 IS IS5481A patent/IS5481A/is unknown
- 2000-05-12 NO NO20002481A patent/NO20002481L/no not_active Application Discontinuation
- 2000-06-05 BG BG104507A patent/BG104507A/bg unknown
Also Published As
Publication number | Publication date |
---|---|
PL340430A1 (en) | 2001-02-12 |
NO20002481L (no) | 2000-07-12 |
IS5481A (is) | 2000-05-09 |
WO1999025352A1 (en) | 1999-05-27 |
EA200000513A1 (ru) | 2000-10-30 |
AR013758A1 (es) | 2001-01-10 |
AU749795B2 (en) | 2002-07-04 |
EP1044000A1 (en) | 2000-10-18 |
CO4970782A1 (es) | 2000-11-07 |
BR9814146A (pt) | 2000-10-03 |
ATE218866T1 (de) | 2002-06-15 |
CN1285747A (zh) | 2001-02-28 |
KR20010032055A (ko) | 2001-04-16 |
DE69806062T2 (de) | 2003-03-20 |
PE20000020A1 (es) | 2000-01-27 |
DE69806062D1 (de) | 2002-07-18 |
CA2309164A1 (en) | 1999-05-27 |
NO20002481D0 (no) | 2000-05-12 |
EP1044000B1 (en) | 2002-06-12 |
AU1522599A (en) | 1999-06-07 |
JP2001522889A (ja) | 2001-11-20 |
IL135994A0 (en) | 2001-05-20 |
HUP0100365A3 (en) | 2002-06-28 |
BG104507A (bg) | 2001-03-30 |
HUP0100365A2 (hu) | 2002-05-29 |
ID24922A (id) | 2000-08-31 |
SK6842000A3 (en) | 2000-12-11 |
TR200001938T2 (tr) | 2001-07-23 |
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