ES2071663T3 - Analogo de fluoxetina. - Google Patents

Analogo de fluoxetina.

Info

Publication number
ES2071663T3
ES2071663T3 ES89311634T ES89311634T ES2071663T3 ES 2071663 T3 ES2071663 T3 ES 2071663T3 ES 89311634 T ES89311634 T ES 89311634T ES 89311634 T ES89311634 T ES 89311634T ES 2071663 T3 ES2071663 T3 ES 2071663T3
Authority
ES
Spain
Prior art keywords
fluoxetine
analog
norfluoxetine
serotonin
inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89311634T
Other languages
English (en)
Inventor
Ray Ward Fuller
David Wayne Robertson
David Taiwai Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2071663T3 publication Critical patent/ES2071663T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA PRESENTE INVENCION PROVEE (S)-NORFLUOXETINA, SALES Y DISOLVENTES FARMACEUTICAMENTE ACEPTABLES DE ELLA CAPACES DE INHIBIR LA ABSORCION DE SEROTONINA.
ES89311634T 1988-11-14 1989-11-10 Analogo de fluoxetina. Expired - Lifetime ES2071663T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27017788A 1988-11-14 1988-11-14

Publications (1)

Publication Number Publication Date
ES2071663T3 true ES2071663T3 (es) 1995-07-01

Family

ID=23030229

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89311634T Expired - Lifetime ES2071663T3 (es) 1988-11-14 1989-11-10 Analogo de fluoxetina.

Country Status (15)

Country Link
EP (1) EP0369685B1 (es)
JP (1) JP2776919B2 (es)
CN (1) CN1042704A (es)
AU (1) AU622942B2 (es)
CA (1) CA2002483C (es)
DE (1) DE68922277T2 (es)
DK (1) DK560289A (es)
ES (1) ES2071663T3 (es)
FI (1) FI895328A7 (es)
HU (1) HUT58041A (es)
IL (1) IL92245A0 (es)
NZ (1) NZ231354A (es)
PT (1) PT92242B (es)
SU (1) SU1750417A3 (es)
ZA (1) ZA898513B (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2103682A1 (es) * 1995-09-20 1997-09-16 Lilly Sa Composicion farmaceutica oral de fluoxetina, solida y con caracteristicas organolepticas mejoradas.
ES2120368A1 (es) * 1996-06-14 1998-10-16 Almirall Prodesfarma Sa Procedimiento de obtencion de n-metil-3-(p-trifluorometilfenoxi)-3-fenilpropilamina y sus sales farmaceuticamente aceptables.

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250571A (en) * 1988-11-14 1993-10-05 Eli Lilly And Company (S)-norfluoxetine in method of inhibiting serotonin uptake
FI910897A7 (fi) * 1990-02-28 1991-08-29 Lilly Co Eli (S)-norfluoksetiiniin liittyviä parannuksia
CA2039103A1 (en) * 1990-03-29 1991-09-30 David Wayne Robertson Improvements in and relating to the selective occupation of serotonin 1c receptors
US5589511A (en) * 1990-08-13 1996-12-31 Sepracor Inc. Method for treating migraine headaches using optically pure S(+) fluoxetine
US5708035A (en) * 1991-02-04 1998-01-13 Sepracor Inc. Methods of use and compositions of R(-) fluoxetine
US5136078A (en) * 1991-02-26 1992-08-04 Eli Lilly And Company Synthesis of b-cyanohydrins
US5136079A (en) * 1991-02-26 1992-08-04 Eli Lilly And Company Regioselective synthesis
DE69227527T2 (de) * 1991-03-01 1999-06-24 Monsanto Co., St. Louis, Mo. Fluoroalkenyl verbindungen und ihre verwendung als schädlingsbekämpfungsmittel
ES2101650B1 (es) * 1995-06-29 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfenoxi) propilamina.
ES2101654B1 (es) * 1995-07-24 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2101655B1 (es) * 1995-07-28 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
US5936124A (en) * 1998-06-22 1999-08-10 Sepacor Inc. Fluoxetine process from benzoylpropionic acid
US6025517A (en) * 1998-08-03 2000-02-15 Sepracor Inc. Fluoxetine process from benzoylacetonitrile
US7034059B2 (en) 2001-07-02 2006-04-25 Sepracor Inc. Methods of using norfluoxetine
US7439399B2 (en) * 2004-06-28 2008-10-21 Teva Pharmaceutical Fine Chemicals Processes for the preparation of atomoxetine hydrochloride
ITMI20061987A1 (it) * 2006-10-16 2008-04-17 Archimica Srl Processo per la sintesi di arilossipropilammine ed eteroarilossipropilammine.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4313896A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Aryloxyphenylpropylamines
US4626549A (en) 1974-01-10 1986-12-02 Eli Lilly And Company Treatment of obesity with aryloxyphenylpropylamines
US4868344A (en) * 1988-03-30 1989-09-19 Aldrich-Boranes, Inc. Novel process of producing phenyl or substituted phenylalkylamine pharmaceutical agents and novel chiral intermediates of high enantiomeric purity useful therein

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2103682A1 (es) * 1995-09-20 1997-09-16 Lilly Sa Composicion farmaceutica oral de fluoxetina, solida y con caracteristicas organolepticas mejoradas.
ES2120368A1 (es) * 1996-06-14 1998-10-16 Almirall Prodesfarma Sa Procedimiento de obtencion de n-metil-3-(p-trifluorometilfenoxi)-3-fenilpropilamina y sus sales farmaceuticamente aceptables.

Also Published As

Publication number Publication date
JPH02193951A (ja) 1990-07-31
FI895328A7 (fi) 1990-05-15
DK560289A (da) 1990-05-15
CA2002483A1 (en) 1990-05-14
SU1750417A3 (ru) 1992-07-23
CA2002483C (en) 1999-08-17
IL92245A0 (en) 1990-07-26
JP2776919B2 (ja) 1998-07-16
HUT58041A (en) 1992-01-28
EP0369685B1 (en) 1995-04-19
DE68922277D1 (de) 1995-05-24
PT92242B (pt) 1995-07-06
PT92242A (pt) 1990-05-31
EP0369685A2 (en) 1990-05-23
HU895848D0 (en) 1990-01-28
AU622942B2 (en) 1992-04-30
CN1042704A (zh) 1990-06-06
ZA898513B (en) 1991-07-31
DK560289D0 (da) 1989-11-09
EP0369685A3 (en) 1991-03-27
FI895328A0 (fi) 1989-11-09
DE68922277T2 (de) 1995-09-21
AU4451689A (en) 1990-05-17
NZ231354A (en) 1991-05-28

Similar Documents

Publication Publication Date Title
ES2071663T3 (es) Analogo de fluoxetina.
NO905514D0 (no) Kombinert anti-inflammatorisk middel samt fremgangsmaate for fremstilling derav.
ATE2667T1 (de) Antidepressiv wirkende derivate des trans-4phenyl-1,2,3,4-tetrahydro-1-naphthalin-amins und pharmazeutische zusammensetzungen daraus.
NO903925D0 (no) Fremgangsmaate for fremstilling av 3-(1-substituert-4-piperazinyl)-1h-indazoler samt anvendelse som legemidler.
DK0960107T3 (da) 6-Thiosubstituerede paclitaxeler
ID28003A (id) Turunan-turunan adamantana
ES2179040T3 (es) Utilizacion de 5-fluoro-2'-desoxi-3'-tiacitidina para el tratamiento de la hepatitis b.
CY2123B1 (en) Isoxazole-4-carboxamides and hydroxyalkylidene-cyanoacetamides drugs containing these compounds and use of such drugs
DK0921812T3 (da) Insulinpræparater, som indeholder NaCi
AR002982A1 (es) Benzonitrilos y benzofluoruros, un procedimiento para prepararlos, su empleo para preparar médicamentos, un médicamento hecho a base de estos compuestos, las preparaciónes farmacéuticas que los contienen y un procedimiento para obtener estas preparaciónes farmacéuticas.
MX9704037A (es) 1,1-dioxidos de 1,2,5-tiadiazolidin-3-ona 2-substituida y composiciones y metodo de uso de los mismos.
IL56413A (en) Substituted heterocyclic benzamides,their preparation and pharmaceutical compositions containing them
ES2043665T3 (es) 6,11-dihidro-11-(4-piperidiliden)-5h-benzo-(5,6)-ciclohepta-(1,2-b)-piridinas y composiciones y metodos de uso.
MX9300399A (es) Derivados heterotriciclicos.
CZ282732B6 (cs) Substituované 1,2,3,4-tetrahydrocyklopent/b/indoly, 1,2,3,3a,4,8a-hexahydrocyklopent/b/indoly a příbuzné sloučeniny, meziprodukty a způsob jejich přípravy a jejich použití jako léčiv
MX9704034A (es) Derivados y composiciones de 1,1-dioxido de 2-arilcarboniloximetil-1,2,5-tiadiazolidin-3-ona substituido y metodo de uso.
NO983177L (no) Anvendelse av 1-enantiomeren av centkroman til fremstilling av et farmasaytisk preparat for behandling eller profylakse av brystkreft
IT8619382A0 (it) Composizioni farmaceutiche per la terapia di cerebropatie su base organica e funzionale.
DK412286D0 (da) 4-acylaminobenzamid-derivater, fremgangsmaade til fremstilling heraf samt mellemprodukter til brug ved fremgangsmaaden
ES2097435T3 (es) Derivados de 2,16-bispiperidinilandrostano monocuaternarios.
MX9704035A (es) 1,1-dioxidos de 2-(fosfiniloximetil)-1,2,5-tiadiazolidin-3-ona substituidos y composiciones y metodo de uso de los mismos.
NO922635L (no) Ny anvendelse av benzimidazolin-2-okso-1-karboksylsyrederivater
NO894516L (no) Fremgangsmaate for fremstilling av 1-aminoalkyl-3-oksosubstituert-4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepin-2-on, og deres anvendelse som medikamenter.
MX9704036A (es) 1,1-dioxidos y composiciones de 2-(2,3,5,6-tetrafluoro-4-piridil)-1,2,5-thiadizaolidin-3-ona y metodo de uso.
FI922864A0 (fi) Terapeutiskt aktiva fluorsubsti- tuerade bensimidazoler, foerfaranden foer deras framstaellning samt deras anvaendning.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 369685

Country of ref document: ES