PE134999A1 - Uso de aminometil-cromanos sustituidos para el impedimento de la degeneracion neuronal y para el estimulo de la regeneracion neuronal - Google Patents
Uso de aminometil-cromanos sustituidos para el impedimento de la degeneracion neuronal y para el estimulo de la regeneracion neuronalInfo
- Publication number
- PE134999A1 PE134999A1 PE1998001138A PE00113898A PE134999A1 PE 134999 A1 PE134999 A1 PE 134999A1 PE 1998001138 A PE1998001138 A PE 1998001138A PE 00113898 A PE00113898 A PE 00113898A PE 134999 A1 PE134999 A1 PE 134999A1
- Authority
- PE
- Peru
- Prior art keywords
- neuronal
- diseases
- aminometil
- chromanes
- impediment
- Prior art date
Links
- 230000009689 neuronal regeneration Effects 0.000 title abstract 2
- 230000004770 neurodegeneration Effects 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000053171 Glial Fibrillary Acidic Human genes 0.000 abstract 1
- 108700005000 Glial Fibrillary Acidic Proteins 0.000 abstract 1
- 208000021642 Muscular disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 206010013663 drug dependence Diseases 0.000 abstract 1
- 230000002518 glial effect Effects 0.000 abstract 1
- 230000012010 growth Effects 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 210000005157 neural retina Anatomy 0.000 abstract 1
- 230000001172 regenerating effect Effects 0.000 abstract 1
- 210000000278 spinal cord Anatomy 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 208000011117 substance-related disease Diseases 0.000 abstract 1
- 238000011477 surgical intervention Methods 0.000 abstract 1
- 231100000167 toxic agent Toxicity 0.000 abstract 1
- 239000003440 toxic substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19751949A DE19751949A1 (de) | 1997-11-24 | 1997-11-24 | Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE134999A1 true PE134999A1 (es) | 2000-03-05 |
Family
ID=7849618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998001138A PE134999A1 (es) | 1997-11-24 | 1998-11-23 | Uso de aminometil-cromanos sustituidos para el impedimento de la degeneracion neuronal y para el estimulo de la regeneracion neuronal |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US6235774B1 (https=) |
| EP (1) | EP1051170B1 (https=) |
| JP (1) | JP2001523716A (https=) |
| KR (1) | KR20010032357A (https=) |
| CN (1) | CN1134256C (https=) |
| AR (1) | AR016973A1 (https=) |
| AT (1) | ATE206615T1 (https=) |
| AU (1) | AU745759B2 (https=) |
| BG (1) | BG64167B1 (https=) |
| CA (1) | CA2311126A1 (https=) |
| DE (2) | DE19751949A1 (https=) |
| DK (1) | DK1051170T3 (https=) |
| ES (1) | ES2164465T3 (https=) |
| HN (1) | HN1998000169A (https=) |
| HU (1) | HUP0004369A3 (https=) |
| IL (1) | IL135904A (https=) |
| IS (1) | IS5496A (https=) |
| MY (1) | MY118414A (https=) |
| NO (1) | NO20002638L (https=) |
| NZ (1) | NZ504656A (https=) |
| PE (1) | PE134999A1 (https=) |
| PL (1) | PL340674A1 (https=) |
| PT (1) | PT1051170E (https=) |
| RU (1) | RU2217140C2 (https=) |
| SI (1) | SI1051170T1 (https=) |
| SV (1) | SV1998000138A (https=) |
| TR (1) | TR200001471T2 (https=) |
| TW (1) | TW524690B (https=) |
| WO (1) | WO1999026621A1 (https=) |
| ZA (1) | ZA9810668B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19751949A1 (de) * | 1997-11-24 | 1999-05-27 | Bayer Ag | Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration |
| UA73981C2 (en) * | 2000-03-10 | 2005-10-17 | Merck Patent Gmbh | (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit |
| BR0109193A (pt) * | 2000-03-17 | 2003-05-27 | Alcon Inc | Compostos com atividade agonista 5-ht2 e 5-ht1a para tratamento do glaucoma |
| US20030207890A1 (en) | 2001-02-23 | 2003-11-06 | Collier Robert J | Compounds with 5-ht1a activity useful for treating disorders of the outer retina |
| DE10058119A1 (de) * | 2000-11-22 | 2002-05-23 | Bayer Ag | Pepinotan-Kit |
| SE0004455D0 (sv) * | 2000-12-01 | 2000-12-01 | Milos Pekny | Method for neuron regeneration in the central nervous system |
| DE10101917A1 (de) * | 2001-01-16 | 2002-07-18 | Bayer Ag | Verwendung von Chromanen |
| AU2002355170B2 (en) * | 2001-07-26 | 2007-06-07 | Merck Patent Gmbh | Novel use of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane and its physiologically acceptable salts |
| BR0212199A (pt) * | 2001-09-12 | 2004-10-05 | Merck Patent Gmbh | Uso de aminometil cromanos substituìdos no tratamento de distúrbios do movimento |
| DE10155075A1 (de) * | 2001-11-09 | 2003-05-22 | Merck Patent Gmbh | Cyclische Sulfonamide |
| ITTO20030140U1 (it) * | 2003-09-16 | 2005-03-17 | Interfila Srl | Matita cosmetica |
| WO2005033092A1 (en) | 2003-09-19 | 2005-04-14 | Galileo Pharmaceuticals, Inc. | Chroman derivatives |
| DE102004017627A1 (de) * | 2004-04-10 | 2005-10-27 | Bayer Healthcare Ag | Verwendung von vollen 5-HT1A-Agonisten zur Hemmung der opiat/opioid-induzierten Atemdepression |
| UA125519C2 (uk) | 2016-07-29 | 2022-04-13 | Суновіон Фармасьютікалз Інк. | Сполуки і композиції і їх застосування |
| CA3032141A1 (en) | 2016-07-29 | 2018-02-01 | Vadim ALEXANDROV | Compounds and compositions and uses thereof |
| RU2651756C1 (ru) * | 2017-05-10 | 2018-04-23 | Федеральное государственное бюджетное образовательное учреждение Высшего Образования Кубанский Государственный Медицинский Университет Министерства Здравоохранения Российской Федерации, КубГМУ | Препарат для предотвращения образования глиальных рубцов |
| BR112020001433A2 (pt) | 2017-08-02 | 2020-07-28 | Sunovion Pharmaceuticals Inc. | compostos de isocromano e usos dos mesmos |
| MX2021010880A (es) | 2019-03-14 | 2022-01-18 | Sunovion Pharmaceuticals Inc | Sales de un compuesto de isocromanilo y formas cristalinas, procesos de preparacion, usos terapeuticos y composiciones farmaceuticas de las mismas. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5300523A (en) | 1988-07-28 | 1994-04-05 | Bayer Aktiengesellschaft | Substituted aminomethyltetralins and their heterocyclic analogues |
| DE3901814A1 (de) * | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
| FR2662355B1 (fr) * | 1990-05-22 | 1994-11-10 | Sanofi Sa | Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux. |
| GB9012316D0 (en) * | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
| DE4135474A1 (de) * | 1991-10-28 | 1993-04-29 | Bayer Ag | 2-aminomethyl-chromane |
| DE19522088A1 (de) | 1995-06-19 | 1997-01-02 | Bayer Ag | Benzisothiazolyl-substituierte Aminomethylchromane |
| DE19751949A1 (de) * | 1997-11-24 | 1999-05-27 | Bayer Ag | Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration |
-
1997
- 1997-11-24 DE DE19751949A patent/DE19751949A1/de not_active Withdrawn
-
1998
- 1998-10-26 HN HN1998000169A patent/HN1998000169A/es unknown
- 1998-11-11 EP EP98961174A patent/EP1051170B1/de not_active Expired - Lifetime
- 1998-11-11 CN CNB988114453A patent/CN1134256C/zh not_active Expired - Fee Related
- 1998-11-11 ES ES98961174T patent/ES2164465T3/es not_active Expired - Lifetime
- 1998-11-11 WO PCT/EP1998/007197 patent/WO1999026621A1/de not_active Ceased
- 1998-11-11 KR KR1020007005593A patent/KR20010032357A/ko not_active Ceased
- 1998-11-11 TR TR2000/01471T patent/TR200001471T2/xx unknown
- 1998-11-11 AT AT98961174T patent/ATE206615T1/de not_active IP Right Cessation
- 1998-11-11 SI SI9830038T patent/SI1051170T1/xx unknown
- 1998-11-11 AU AU16685/99A patent/AU745759B2/en not_active Ceased
- 1998-11-11 DK DK98961174T patent/DK1051170T3/da active
- 1998-11-11 DE DE59801724T patent/DE59801724D1/de not_active Expired - Fee Related
- 1998-11-11 CA CA002311126A patent/CA2311126A1/en not_active Abandoned
- 1998-11-11 NZ NZ504656A patent/NZ504656A/en unknown
- 1998-11-11 TW TW087118723A patent/TW524690B/zh not_active IP Right Cessation
- 1998-11-11 PT PT81108222T patent/PT1051170E/pt unknown
- 1998-11-11 US US09/554,971 patent/US6235774B1/en not_active Expired - Fee Related
- 1998-11-11 RU RU2000116547/14A patent/RU2217140C2/ru not_active IP Right Cessation
- 1998-11-11 JP JP2000521823A patent/JP2001523716A/ja not_active Withdrawn
- 1998-11-11 PL PL98340674A patent/PL340674A1/xx unknown
- 1998-11-11 IL IL13590498A patent/IL135904A/xx active IP Right Grant
- 1998-11-11 HU HU0004369A patent/HUP0004369A3/hu unknown
- 1998-11-19 AR ARP980105881A patent/AR016973A1/es not_active Application Discontinuation
- 1998-11-20 MY MYPI98005285A patent/MY118414A/en unknown
- 1998-11-23 PE PE1998001138A patent/PE134999A1/es not_active Application Discontinuation
- 1998-11-23 ZA ZA9810668A patent/ZA9810668B/xx unknown
- 1998-11-24 SV SV1998000138A patent/SV1998000138A/es unknown
-
2000
- 2000-05-15 IS IS5496A patent/IS5496A/is unknown
- 2000-05-22 BG BG104466A patent/BG64167B1/bg unknown
- 2000-05-23 NO NO20002638A patent/NO20002638L/no unknown
-
2001
- 2001-03-09 US US09/803,621 patent/US6331561B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE134999A1 (es) | Uso de aminometil-cromanos sustituidos para el impedimento de la degeneracion neuronal y para el estimulo de la regeneracion neuronal | |
| JP3553083B2 (ja) | 末梢性活性抗痛覚過敏オピエート | |
| ES2399738T3 (es) | Procedimiento y composición para el tratamiento de cicatrices | |
| ES2164040T1 (es) | Uso de agonistas del sitio de union de la glicina o de inhibidores de la absorcion de la glicina para el tratamiento de trastornos neuropsiquiatricos. | |
| BR0010869A (pt) | Método para administrar um corticosteróide a um segmento posterior de um olho e dispositivo de liberação sustentada implantável | |
| ES2141706T3 (es) | Formulaciones y su empleo en el tratamiento de enfermedades neurologicas. | |
| JP2003529548A5 (https=) | ||
| BR9808938A (pt) | Composto, composição farmacêutica, uso de um composto, processos para o tratamento de um distúrbio ou doença de um corpo de animal vivo e para a preparação de um composto, e, uso de bloqueadores de canal de cloreto | |
| BRPI0820800B8 (pt) | dispositivo médico implantável para liberação controlada de droga | |
| BRPI0412526A (pt) | composto, uso de um composto, composição farmacêutica, formulação em aerossol farmacêutica, e, método para o tratamento de um paciente humano ou animal com uma condição anti-inflamatória e/ou alérgica | |
| EA200300046A1 (ru) | Быстро увеличивающаяся в объеме композиция для удерживания и контролированного выделения терапевтических агентов в желудке и лекарственные формы, включающие композицию | |
| BR9809453A (pt) | Composição de suprimento de medicamento para a liberação controlada de um ingrediente ativo dentro do meio-ambiente do estÈmago, uso da mesma, formulação farmacêutica, processo para obter gastrorretenção, para o tratamento ou profilaxia de uma doença, para melhorar a absorção gastrointestinal de medicamentos, e para a preparação de uma composição, e, estojo de partes para uso no tratamento de infecção por h. pylori. | |
| DE69715049D1 (de) | Tranilast enthaltendes externum und verfahren zu dessen herstellung | |
| SI9111227B (sl) | Farmacevtski preprat z aktivno materijo Flupirtin za zdravljenje bolezni, ki se nanašajo na napetost mišic | |
| BR0107983A (pt) | Uso de pramipexol para o tratamento de enfermidades decorrentes de vìcios | |
| BR0210034A (pt) | Conjunto de partes, método para tratamento de trombose, uso de um composto, formulação farmacêutica, uso e processo para preparação da mesma, e, composto | |
| BR0010531A (pt) | Composições e usos de et743 para tratamento de câncer | |
| DE69602412D1 (de) | Ophthalmische Zubereitung zur Behandlung oder Prävention von trockenem Auge und Krankheiten, die dadurch verursacht werden, enthaltend 12-Sulfodehydroabietsäure | |
| DE50110262D1 (de) | Verwendung von bradycardica bei der behandlung von mit hypertrophie einhergehenden myocarderkrankungen und neue arzneimittelkombinationen | |
| BR9807796A (pt) | Processos para tratar da incontinência urinária, de vertigem e da doença do movimento, e, composição farmacêutica. | |
| BR0316040A (pt) | Composto, métodos para tratar doenças, para tratar edema macular, degeneração macular, aumentar a velocidade do sangue retinal e da cabeça do nervo óptico, aumentar a tensão de oxigênio retinal e do nervo óptico e/ou um efeito neuroprotetor, para prevenir a repolarização ou a hiperpolarização de uma célula de mamìfero contendo canal de potássio, e para tratar do diabete, e, composição | |
| DE60018409D1 (de) | Verwendung von antiseptika zur herstelllung von arzneimitteln zur prophylaxe und behandlung von infektionen und/ oder funktionellen gewebeumformungen im körperinneren | |
| MXPA02009881A (es) | Nuevos medicamentos intracorporales para tratamiento fototerapeutico con alta energia de enfermedad. | |
| BR9909478A (pt) | Novos tratamentos para vários distúrbios do sistema nervoso | |
| DE69426530D1 (de) | Pharmazeutische zusammensetzung zur förderung der gewebeheilung und -regenerierung und darreichungssatz |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |