PE134999A1 - Uso de aminometil-cromanos sustituidos para el impedimento de la degeneracion neuronal y para el estimulo de la regeneracion neuronal - Google Patents
Uso de aminometil-cromanos sustituidos para el impedimento de la degeneracion neuronal y para el estimulo de la regeneracion neuronalInfo
- Publication number
- PE134999A1 PE134999A1 PE1998001138A PE00113898A PE134999A1 PE 134999 A1 PE134999 A1 PE 134999A1 PE 1998001138 A PE1998001138 A PE 1998001138A PE 00113898 A PE00113898 A PE 00113898A PE 134999 A1 PE134999 A1 PE 134999A1
- Authority
- PE
- Peru
- Prior art keywords
- neuronal
- diseases
- aminometil
- chromanes
- impediment
- Prior art date
Links
- 230000009689 neuronal regeneration Effects 0.000 title abstract 2
- 230000004770 neurodegeneration Effects 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000053171 Glial Fibrillary Acidic Human genes 0.000 abstract 1
- 108700005000 Glial Fibrillary Acidic Proteins 0.000 abstract 1
- 208000021642 Muscular disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 206010013663 drug dependence Diseases 0.000 abstract 1
- 230000002518 glial effect Effects 0.000 abstract 1
- 230000012010 growth Effects 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 210000005157 neural retina Anatomy 0.000 abstract 1
- 230000001172 regenerating effect Effects 0.000 abstract 1
- 210000000278 spinal cord Anatomy 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 208000011117 substance-related disease Diseases 0.000 abstract 1
- 238000011477 surgical intervention Methods 0.000 abstract 1
- 231100000167 toxic agent Toxicity 0.000 abstract 1
- 239000003440 toxic substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19751949A DE19751949A1 (de) | 1997-11-24 | 1997-11-24 | Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE134999A1 true PE134999A1 (es) | 2000-03-05 |
Family
ID=7849618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998001138A PE134999A1 (es) | 1997-11-24 | 1998-11-23 | Uso de aminometil-cromanos sustituidos para el impedimento de la degeneracion neuronal y para el estimulo de la regeneracion neuronal |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US6235774B1 (https=) |
| EP (1) | EP1051170B1 (https=) |
| JP (1) | JP2001523716A (https=) |
| KR (1) | KR20010032357A (https=) |
| CN (1) | CN1134256C (https=) |
| AR (1) | AR016973A1 (https=) |
| AT (1) | ATE206615T1 (https=) |
| AU (1) | AU745759B2 (https=) |
| BG (1) | BG64167B1 (https=) |
| CA (1) | CA2311126A1 (https=) |
| DE (2) | DE19751949A1 (https=) |
| DK (1) | DK1051170T3 (https=) |
| ES (1) | ES2164465T3 (https=) |
| HN (1) | HN1998000169A (https=) |
| HU (1) | HUP0004369A3 (https=) |
| IL (1) | IL135904A (https=) |
| IS (1) | IS5496A (https=) |
| MY (1) | MY118414A (https=) |
| NO (1) | NO20002638D0 (https=) |
| NZ (1) | NZ504656A (https=) |
| PE (1) | PE134999A1 (https=) |
| PL (1) | PL340674A1 (https=) |
| PT (1) | PT1051170E (https=) |
| RU (1) | RU2217140C2 (https=) |
| SI (1) | SI1051170T1 (https=) |
| SV (1) | SV1998000138A (https=) |
| TR (1) | TR200001471T2 (https=) |
| TW (1) | TW524690B (https=) |
| WO (1) | WO1999026621A1 (https=) |
| ZA (1) | ZA9810668B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19751949A1 (de) * | 1997-11-24 | 1999-05-27 | Bayer Ag | Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration |
| UA73981C2 (en) * | 2000-03-10 | 2005-10-17 | Merck Patent Gmbh | (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit |
| MXPA02009071A (es) * | 2000-03-17 | 2003-05-23 | Alcon Inc | Compuestos con actividad agonista de 5-ht 1a para tratar glaucoma.. |
| US20030207890A1 (en) | 2001-02-23 | 2003-11-06 | Collier Robert J | Compounds with 5-ht1a activity useful for treating disorders of the outer retina |
| DE10058119A1 (de) * | 2000-11-22 | 2002-05-23 | Bayer Ag | Pepinotan-Kit |
| SE0004455D0 (sv) * | 2000-12-01 | 2000-12-01 | Milos Pekny | Method for neuron regeneration in the central nervous system |
| DE10101917A1 (de) * | 2001-01-16 | 2002-07-18 | Bayer Ag | Verwendung von Chromanen |
| PT1408964E (pt) * | 2001-07-26 | 2007-05-31 | Merck Patent Gmbh | Utilização de 2-5-(4-fluorofenil) -3-piridilmetilaminometil-cromano e de seus sais fisiologicamente aceitáveis. |
| ATE341322T1 (de) * | 2001-09-12 | 2006-10-15 | Merck Patent Gmbh | Verwendung von aminomethyl chromanen zur behandlung der nebenwirkungen von neuroleptika |
| DE10155075A1 (de) * | 2001-11-09 | 2003-05-22 | Merck Patent Gmbh | Cyclische Sulfonamide |
| ITTO20030140U1 (it) * | 2003-09-16 | 2005-03-17 | Interfila Srl | Matita cosmetica |
| WO2005033093A1 (en) | 2003-09-19 | 2005-04-14 | Galileo Pharmaceuticals, Inc. | 7,8-bicycloalkyl-chroman derivatives |
| DE102004017627A1 (de) * | 2004-04-10 | 2005-10-27 | Bayer Healthcare Ag | Verwendung von vollen 5-HT1A-Agonisten zur Hemmung der opiat/opioid-induzierten Atemdepression |
| PT3494119T (pt) | 2016-07-29 | 2024-12-10 | Pgi Drug Discovery Llc | Compostos e composições e seus usos |
| MA45795A (fr) | 2016-07-29 | 2019-06-05 | Sunovion Pharmaceuticals Inc | Composés et compositions, et utilisations associées |
| RU2651756C1 (ru) * | 2017-05-10 | 2018-04-23 | Федеральное государственное бюджетное образовательное учреждение Высшего Образования Кубанский Государственный Медицинский Университет Министерства Здравоохранения Российской Федерации, КубГМУ | Препарат для предотвращения образования глиальных рубцов |
| CA3070993C (en) * | 2017-08-02 | 2025-05-20 | Sunovion Pharmaceuticals Inc. | ISOCHROMANE COMPOUNDS AND THEIR USES |
| EP3938045A1 (en) | 2019-03-14 | 2022-01-19 | Sunovion Pharmaceuticals Inc. | Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5300523A (en) | 1988-07-28 | 1994-04-05 | Bayer Aktiengesellschaft | Substituted aminomethyltetralins and their heterocyclic analogues |
| DE3901814A1 (de) * | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
| FR2662355B1 (fr) * | 1990-05-22 | 1994-11-10 | Sanofi Sa | Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux. |
| GB9012316D0 (en) * | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
| DE4135474A1 (de) | 1991-10-28 | 1993-04-29 | Bayer Ag | 2-aminomethyl-chromane |
| DE19522088A1 (de) | 1995-06-19 | 1997-01-02 | Bayer Ag | Benzisothiazolyl-substituierte Aminomethylchromane |
| DE19751949A1 (de) * | 1997-11-24 | 1999-05-27 | Bayer Ag | Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration |
-
1997
- 1997-11-24 DE DE19751949A patent/DE19751949A1/de not_active Withdrawn
-
1998
- 1998-10-26 HN HN1998000169A patent/HN1998000169A/es unknown
- 1998-11-11 DK DK98961174T patent/DK1051170T3/da active
- 1998-11-11 PT PT81108222T patent/PT1051170E/pt unknown
- 1998-11-11 TW TW087118723A patent/TW524690B/zh not_active IP Right Cessation
- 1998-11-11 CN CNB988114453A patent/CN1134256C/zh not_active Expired - Fee Related
- 1998-11-11 CA CA002311126A patent/CA2311126A1/en not_active Abandoned
- 1998-11-11 ES ES98961174T patent/ES2164465T3/es not_active Expired - Lifetime
- 1998-11-11 TR TR2000/01471T patent/TR200001471T2/xx unknown
- 1998-11-11 US US09/554,971 patent/US6235774B1/en not_active Expired - Fee Related
- 1998-11-11 AT AT98961174T patent/ATE206615T1/de not_active IP Right Cessation
- 1998-11-11 AU AU16685/99A patent/AU745759B2/en not_active Ceased
- 1998-11-11 WO PCT/EP1998/007197 patent/WO1999026621A1/de not_active Ceased
- 1998-11-11 PL PL98340674A patent/PL340674A1/xx unknown
- 1998-11-11 RU RU2000116547/14A patent/RU2217140C2/ru not_active IP Right Cessation
- 1998-11-11 HU HU0004369A patent/HUP0004369A3/hu unknown
- 1998-11-11 NZ NZ504656A patent/NZ504656A/en unknown
- 1998-11-11 DE DE59801724T patent/DE59801724D1/de not_active Expired - Fee Related
- 1998-11-11 KR KR1020007005593A patent/KR20010032357A/ko not_active Ceased
- 1998-11-11 JP JP2000521823A patent/JP2001523716A/ja not_active Withdrawn
- 1998-11-11 EP EP98961174A patent/EP1051170B1/de not_active Expired - Lifetime
- 1998-11-11 SI SI9830038T patent/SI1051170T1/xx unknown
- 1998-11-11 IL IL13590498A patent/IL135904A/xx active IP Right Grant
- 1998-11-19 AR ARP980105881A patent/AR016973A1/es not_active Application Discontinuation
- 1998-11-20 MY MYPI98005285A patent/MY118414A/en unknown
- 1998-11-23 ZA ZA9810668A patent/ZA9810668B/xx unknown
- 1998-11-23 PE PE1998001138A patent/PE134999A1/es not_active Application Discontinuation
- 1998-11-24 SV SV1998000138A patent/SV1998000138A/es unknown
-
2000
- 2000-05-15 IS IS5496A patent/IS5496A/is unknown
- 2000-05-22 BG BG104466A patent/BG64167B1/bg unknown
- 2000-05-23 NO NO20002638A patent/NO20002638D0/no unknown
-
2001
- 2001-03-09 US US09/803,621 patent/US6331561B2/en not_active Expired - Fee Related
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |