MXPA02009881A - Nuevos medicamentos intracorporales para tratamiento fototerapeutico con alta energia de enfermedad. - Google Patents
Nuevos medicamentos intracorporales para tratamiento fototerapeutico con alta energia de enfermedad.Info
- Publication number
- MXPA02009881A MXPA02009881A MXPA02009881A MXPA02009881A MXPA02009881A MX PA02009881 A MXPA02009881 A MX PA02009881A MX PA02009881 A MXPA02009881 A MX PA02009881A MX PA02009881 A MXPA02009881 A MX PA02009881A MX PA02009881 A MXPA02009881 A MX PA02009881A
- Authority
- MX
- Mexico
- Prior art keywords
- medicaments
- high energy
- disease
- energy phototherapeutic
- phototherapeutic treatment
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 4
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 125000001834 xanthenyl group Chemical class C1=CC=CC=2OC3=CC=CC=C3C(C12)* 0.000 abstract 2
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/008—Two-Photon or Multi-Photon PDT, e.g. with upconverting dyes or photosensitisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00057—Light
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22051—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
- A61B2017/22062—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation to be filled with liquid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
- A61B2017/22087—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance photodynamic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/819—Multifunctional antigen or antibody
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Radiology & Medical Imaging (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
Abstract
Se describen nuevos medicamentos radiodensos, intracorporales y ciertos usos médicos y métodos para el uso de medicamentos fototerapéuticos de alta energía para tratamiento de tejido humano o de animal, en donde un componente activo primario de estos medicamentos es xanteno halogenado o derivado de xanteno halogenado.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19509000P | 2000-04-06 | 2000-04-06 | |
US09/817,448 US20020001567A1 (en) | 1998-12-21 | 2001-03-26 | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
PCT/US2001/010870 WO2001076595A1 (en) | 2000-04-06 | 2001-04-03 | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02009881A true MXPA02009881A (es) | 2003-06-19 |
Family
ID=26890690
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02009881A MXPA02009881A (es) | 2000-04-06 | 2001-04-03 | Nuevos medicamentos intracorporales para tratamiento fototerapeutico con alta energia de enfermedad. |
Country Status (11)
Country | Link |
---|---|
US (3) | US20020001567A1 (es) |
EP (1) | EP1292298B1 (es) |
JP (1) | JP2003531834A (es) |
AR (1) | AR028321A1 (es) |
AT (1) | ATE357912T1 (es) |
AU (1) | AU2001253125A1 (es) |
CA (1) | CA2405554A1 (es) |
DE (1) | DE60127552T2 (es) |
ES (1) | ES2283406T3 (es) |
MX (1) | MXPA02009881A (es) |
WO (1) | WO2001076595A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7390668B2 (en) * | 1996-10-30 | 2008-06-24 | Provectus Pharmatech, Inc. | Intracorporeal medicaments for photodynamic treatment of disease |
US7648695B2 (en) | 1998-08-06 | 2010-01-19 | Provectus Pharmatech, Inc. | Medicaments for chemotherapeutic treatment of disease |
US8557298B2 (en) * | 1998-08-06 | 2013-10-15 | Provectus Pharmatech, Inc. | Medicaments for chemotherapeutic treatment of disease |
US20090117199A1 (en) * | 1998-08-06 | 2009-05-07 | Scott Timothy C | Method of treatment of cancer |
US6986740B2 (en) * | 1998-11-02 | 2006-01-17 | Xantech Pharmaceuticals, Inc. | Ultrasound contrast using halogenated xanthenes |
US20020001567A1 (en) * | 1998-12-21 | 2002-01-03 | Photogen, Inc. | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
US8470296B2 (en) * | 1998-12-21 | 2013-06-25 | Provectus Pharmatech, Inc. | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
US20100076246A1 (en) * | 1998-12-21 | 2010-03-25 | Provectus Pharmatech, Inc. | Intracorporeal Medicaments for High Energy Phototherapeutic Treatment of Disease |
US20050053895A1 (en) | 2003-09-09 | 2005-03-10 | The Procter & Gamble Company Attention: Chief Patent Counsel | Illuminated electric toothbrushes emitting high luminous intensity toothbrush |
US7465312B2 (en) | 2006-05-02 | 2008-12-16 | Green Medical, Inc. | Systems and methods for treating superficial venous malformations like spider veins |
US20070299431A1 (en) * | 2006-05-02 | 2007-12-27 | Green Medical, Inc. | Systems and methods for treating superficial venous malformations like spider veins |
US20090088625A1 (en) * | 2007-10-01 | 2009-04-02 | Kenneth Oosting | Photonic Based Non-Invasive Surgery System That Includes Automated Cell Control and Eradication Via Pre-Calculated Feed-Forward Control Plus Image Feedback Control For Targeted Energy Delivery |
CA2828940C (en) * | 2011-03-10 | 2024-04-16 | Provectus Pharmaceuticals, Inc. | Combination of local and systemic immunomodulative therapies for enhanced treatment of cancer |
CN111087376B (zh) * | 2019-12-30 | 2021-08-03 | 厦门大学 | 一种钆掺杂孟加拉玫瑰纳米点及其制备方法和应用 |
Family Cites Families (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3868950A (en) * | 1970-09-24 | 1975-03-04 | Yoshio Kato | Body treating apparatus |
US4066650A (en) * | 1971-02-11 | 1978-01-03 | Egyud Laszlo G | Keto-aldehyde-amine addition products and method of making same |
US3986513A (en) * | 1976-01-29 | 1976-10-19 | Joseph Lester Stuhl | Apparatus for irradiating the skin |
IE47132B1 (en) * | 1977-08-19 | 1983-12-28 | Roche Products Ltd | Novel nitroimidazoles and pharmaceutical preparations containing these as well as their manufacture |
US4172979A (en) * | 1978-06-15 | 1979-10-30 | Morrison Richard A | Method and apparatus for automatically providing radiation therapy treatment conforming to a desired volume of tissue |
US4282232A (en) * | 1979-04-26 | 1981-08-04 | Research Corporation | Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof |
US4371540A (en) * | 1979-09-14 | 1983-02-01 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nitroimidazoles of low toxicity and high activity as radiosensitizers of hypoxic tumor cells |
US4444189A (en) * | 1981-12-21 | 1984-04-24 | Seiverd Paul J | Phototherapy booth |
US4462992A (en) * | 1982-02-08 | 1984-07-31 | Research Corporation | Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof |
US4846789A (en) * | 1982-07-19 | 1989-07-11 | L. S. Van Landingham, Jr. | Combatting internal parasites in warm blooded animals |
US4490543A (en) * | 1982-11-12 | 1984-12-25 | University Of Northern Iowa Foundation | Low toxicity radiation sensitizer |
US4691332A (en) * | 1983-03-14 | 1987-09-01 | American Science And Engineering, Inc. | High energy computed tomography |
US4599227A (en) * | 1983-11-07 | 1986-07-08 | Wisconsin Alumni Research Foundation | Injectable pharmaceutical preparation for the induction of multiple follicular growth |
US4647578A (en) * | 1983-12-02 | 1987-03-03 | Sterling Drug Inc. | Phototoxic insecticidal compositions and method of use thereof |
US4681091A (en) * | 1984-08-03 | 1987-07-21 | Picker Donald H | Combination modality cancer therapy |
US4789501A (en) * | 1984-11-19 | 1988-12-06 | The Curators Of The University Of Missouri | Glass microspheres |
US5215738A (en) * | 1985-05-03 | 1993-06-01 | Sri International | Benzamide and nicotinamide radiosensitizers |
HU195487B (en) * | 1985-06-04 | 1988-05-30 | Egyt Gyogyszervegyeszeti Gyar | Process for producing quinoline derivatives |
FR2596989B1 (fr) * | 1986-04-14 | 1990-05-18 | Air Liquide | Produit de radiosensibilisation des tissus biologiques en radiotherapie |
US5624925A (en) * | 1986-09-25 | 1997-04-29 | Sri International | 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents |
US5175287A (en) * | 1986-09-25 | 1992-12-29 | S R I International | Process for preparing 1,2,4-benzotriazine oxides |
US5019368A (en) * | 1989-02-23 | 1991-05-28 | Cancer Biologics, Inc. | Detection of necrotic malignant tissue and associated therapy |
US4921963A (en) * | 1987-04-13 | 1990-05-01 | British Columbia Cancer Foundation | Platinum complexes with one radiosensitizing ligand |
US5026694A (en) * | 1987-04-13 | 1991-06-25 | The British Columbia Cancer Foundation | Platinum complexes with one radiosensitizing ligand |
US5304654A (en) * | 1987-06-10 | 1994-04-19 | Yasunori Nishijima | Fluorine-containing nitroimidazole compounds |
CA1329206C (en) * | 1987-06-10 | 1994-05-03 | Tsutomu Kagiya | Fluorine-containing nitroazole derivatives and radiosensitizer comprising the same |
US4856528A (en) * | 1987-06-26 | 1989-08-15 | John Hopkins University | Tumor volume determination |
US4957481A (en) * | 1987-10-01 | 1990-09-18 | U.S. Bioscience | Photodynamic therapeutic technique |
JPH0819111B2 (ja) * | 1987-10-22 | 1996-02-28 | ポーラ化成工業株式会社 | 2―ニトロイミダゾール誘導体及びこれを有効成分とする放射線増感剤 |
US5053006A (en) * | 1988-04-19 | 1991-10-01 | Watson Brant D | Method for the permanent occlusion of arteries |
US4897423A (en) * | 1988-08-02 | 1990-01-30 | Merck & Co. Inc. | Dinitrobenzenesulfonamides |
US4880821A (en) * | 1988-08-17 | 1989-11-14 | Merck & Co., Inc. | α-nitroalkylnitrobenzenesulfonamides |
US5177073A (en) * | 1988-09-30 | 1993-01-05 | Baylor Research Institute | Therapeutic compositions derived from photoactive compounds |
US4954515A (en) * | 1988-11-25 | 1990-09-04 | Warner-Lambert Company | Haloalkylaminomethyl-2-nitro-1H-imidazoles |
US5036089A (en) * | 1988-11-25 | 1991-07-30 | Warner-Lambert Company | 2-oxazolidinone derivatives of nitroimidazoles and pharmaceutical compositions useful as sensitizing agents |
US5036096A (en) * | 1988-11-25 | 1991-07-30 | Warner-Lambert Company | Aziridino derivatives of nitroimidazoles and pharmaceutical compositions of selected derivatives |
IL92597A0 (en) * | 1988-12-14 | 1990-08-31 | Yasunori Nishijima President K | Novel fluorine-containing 2-nitroimidazole derivatives and radiosensitizer comprising the same |
US5457183A (en) * | 1989-03-06 | 1995-10-10 | Board Of Regents, The University Of Texas System | Hydroxylated texaphyrins |
US5599923A (en) * | 1989-03-06 | 1997-02-04 | Board Of Regents, University Of Tx | Texaphyrin metal complexes having improved functionalization |
US5641764A (en) * | 1989-03-31 | 1997-06-24 | Peter Maccallum Institute | Halogenated DNA ligand radiosensitizers for cancer therapy |
US5008907A (en) * | 1989-05-31 | 1991-04-16 | The Regents Of The University Of California | Therapy x-ray scanner |
US4973848A (en) * | 1989-07-28 | 1990-11-27 | J. Mccaughan | Laser apparatus for concurrent analysis and treatment |
US5733572A (en) * | 1989-12-22 | 1998-03-31 | Imarx Pharmaceutical Corp. | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles |
JP2626727B2 (ja) * | 1990-01-26 | 1997-07-02 | ポーラ化成工業株式会社 | 2―ニトロイミダゾール誘導体、その製造法及びこれを有効成分とする放射線増感剤 |
US5147652A (en) * | 1990-07-03 | 1992-09-15 | Cell Research Corporation | Autobiotics and their use in eliminating nonself cells in vivo |
US5282781A (en) * | 1990-10-25 | 1994-02-01 | Omnitron International Inc. | Source wire for localized radiation treatment of tumors |
US5654423A (en) * | 1990-11-21 | 1997-08-05 | Regents Of The University Of California | Boronated metalloporphyrine and therapeutic methods |
US5149801A (en) * | 1990-11-21 | 1992-09-22 | The Regents Of The University Of California | Boronated porphyrin compounds |
US5294715A (en) * | 1991-02-01 | 1994-03-15 | University Of Pittsburgh | Acridine-intercalator based hypoxia selective cytotoxins |
US5128139A (en) * | 1991-02-15 | 1992-07-07 | Nu Skin International, Inc. | Composition containing liposome-entrapped grapefruit seed extract and method for making |
US5225182A (en) * | 1991-10-31 | 1993-07-06 | Sharma Yash P | Vectored drug delivery system using a cephaloplastin linking agent and a methed of using the system |
MX9304399A (es) * | 1992-07-31 | 1994-02-28 | Warner Lambert Co | Proceso novedoso para preparar [[2-bromoetil)-amino]metil]-2-nitro-1h-imidazol-1-etanol quiral y compuestos relacionados. |
US5552452A (en) * | 1993-03-15 | 1996-09-03 | Arch Development Corp. | Organic tissue glue for closure of wounds |
CN1148812A (zh) * | 1994-03-28 | 1997-04-30 | 尼科梅德成像有限公司 | “脂质体” |
US5502094A (en) * | 1994-05-20 | 1996-03-26 | Minnesota Mining And Manufacturing Company | Physiologically acceptable emulsions containing perfluorocarbon ether hydrides and methods for use |
US5935942A (en) * | 1994-12-14 | 1999-08-10 | Zeimer; Ran | Selective and non-invasive visualization or treatment of vasculature |
US5602142A (en) * | 1994-12-21 | 1997-02-11 | Evanston Hospital Corporation | DNA-affinic hypoxia selective cytotoxins |
US5576013A (en) * | 1995-03-21 | 1996-11-19 | Eastern Virginia Medical School | Treating vascular and neoplastic tissues |
US5700825A (en) * | 1995-03-31 | 1997-12-23 | Florida State University | Radiosensitizing diamines and their pharmaceutical preparations |
US5780052A (en) * | 1995-04-24 | 1998-07-14 | Northeastern University | Compositions and methods useful for inhibiting cell death and for delivering an agent into a cell |
US5591422A (en) * | 1995-06-02 | 1997-01-07 | Pharmacyclics, Inc. | Texaphyrin complexes having improved functionalization |
US5780653A (en) * | 1995-06-07 | 1998-07-14 | Vivorx Pharmaceuticals, Inc. | Nitrophenyl, 10-deacetylated substituted taxol derivatives as dual functional cytotoxic/radiosensitizers |
NZ286038A (en) * | 1996-02-21 | 1998-10-28 | Bodyworks Healthcare Ltd | Knee brace includes at least one arm offset along a length thereof |
WO1998001131A1 (fr) * | 1996-07-05 | 1998-01-15 | Hitachi, Ltd. | Medicaments induisant une action ultrasonore et appareil d'utilisation de ces medicaments |
US6331286B1 (en) * | 1998-12-21 | 2001-12-18 | Photogen, Inc. | Methods for high energy phototherapeutics |
US5832931A (en) * | 1996-10-30 | 1998-11-10 | Photogen, Inc. | Method for improved selectivity in photo-activation and detection of molecular diagnostic agents |
US6493570B1 (en) * | 1998-11-02 | 2002-12-10 | Photogen, Inc. | Method for improved imaging and photodynamic therapy |
US5829448A (en) * | 1996-10-30 | 1998-11-03 | Photogen, Inc. | Method for improved selectivity in photo-activation of molecular agents |
US6045774A (en) * | 1997-01-10 | 2000-04-04 | Epicyte Pharmaceutical Inc. | J chain polypeptide targeting molecule linked to an imaging agent |
US5827186A (en) * | 1997-04-11 | 1998-10-27 | Light Sciences Limited Partnership | Method and PDT probe for minimizing CT and MRI image artifacts |
JP3880150B2 (ja) * | 1997-06-02 | 2007-02-14 | 松下電器産業株式会社 | 弾性表面波素子 |
CN1200698C (zh) * | 1998-03-09 | 2005-05-11 | 伊斯塔药品公司 | 角膜硬化剂在制备治疗眼睛屈光不正的药物中的用途 |
US7648695B2 (en) * | 1998-08-06 | 2010-01-19 | Provectus Pharmatech, Inc. | Medicaments for chemotherapeutic treatment of disease |
US20020001567A1 (en) * | 1998-12-21 | 2002-01-03 | Photogen, Inc. | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
AR022404A1 (es) * | 1999-01-25 | 2002-09-04 | Photogen Inc | Metodo y agentes para la terapia de radiacion mejorada |
US6707755B1 (en) * | 2002-12-11 | 2004-03-16 | Intel Corporation | High voltage driver |
-
2001
- 2001-03-26 US US09/817,448 patent/US20020001567A1/en not_active Abandoned
- 2001-04-03 MX MXPA02009881A patent/MXPA02009881A/es unknown
- 2001-04-03 ES ES01926602T patent/ES2283406T3/es not_active Expired - Lifetime
- 2001-04-03 WO PCT/US2001/010870 patent/WO2001076595A1/en active IP Right Grant
- 2001-04-03 AU AU2001253125A patent/AU2001253125A1/en not_active Abandoned
- 2001-04-03 DE DE60127552T patent/DE60127552T2/de not_active Expired - Lifetime
- 2001-04-03 EP EP01926602A patent/EP1292298B1/en not_active Expired - Lifetime
- 2001-04-03 AT AT01926602T patent/ATE357912T1/de active
- 2001-04-03 CA CA002405554A patent/CA2405554A1/en not_active Abandoned
- 2001-04-03 JP JP2001574113A patent/JP2003531834A/ja active Pending
- 2001-04-06 AR ARP010101661A patent/AR028321A1/es not_active Application Discontinuation
-
2002
- 2002-12-30 US US10/331,854 patent/US6991776B2/en not_active Expired - Lifetime
-
2006
- 2006-10-02 US US11/542,533 patent/US20070078076A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2001253125A1 (en) | 2001-10-23 |
DE60127552T2 (de) | 2007-12-13 |
CA2405554A1 (en) | 2001-10-18 |
US20020001567A1 (en) | 2002-01-03 |
AR028321A1 (es) | 2003-05-07 |
EP1292298A4 (en) | 2003-06-25 |
EP1292298A1 (en) | 2003-03-19 |
US20070078076A1 (en) | 2007-04-05 |
ATE357912T1 (de) | 2007-04-15 |
US20030125376A1 (en) | 2003-07-03 |
WO2001076595A1 (en) | 2001-10-18 |
JP2003531834A (ja) | 2003-10-28 |
ES2283406T3 (es) | 2007-11-01 |
US6991776B2 (en) | 2006-01-31 |
EP1292298B1 (en) | 2007-03-28 |
DE60127552D1 (de) | 2007-05-10 |
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