PL340674A1 - Application of substituted aminomethyl chromanes in preventing degeneration of nerve cells and stimulating their regeneration - Google Patents

Application of substituted aminomethyl chromanes in preventing degeneration of nerve cells and stimulating their regeneration

Info

Publication number
PL340674A1
PL340674A1 PL98340674A PL34067498A PL340674A1 PL 340674 A1 PL340674 A1 PL 340674A1 PL 98340674 A PL98340674 A PL 98340674A PL 34067498 A PL34067498 A PL 34067498A PL 340674 A1 PL340674 A1 PL 340674A1
Authority
PL
Poland
Prior art keywords
stimulating
regeneration
application
nerve cells
substituted aminomethyl
Prior art date
Application number
PL98340674A
Other languages
English (en)
Inventor
Thomas Fahrig
Irene Gerlach
Ervin Horvath
Reinhard Jork
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PL340674A1 publication Critical patent/PL340674A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL98340674A 1997-11-24 1998-11-11 Application of substituted aminomethyl chromanes in preventing degeneration of nerve cells and stimulating their regeneration PL340674A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19751949A DE19751949A1 (de) 1997-11-24 1997-11-24 Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
PCT/EP1998/007197 WO1999026621A1 (de) 1997-11-24 1998-11-11 Verwendung von substituierten aminomethyl-chromanen zur verhinderung der neuronalen degeneration und zur förderung der neuronalen regeneration

Publications (1)

Publication Number Publication Date
PL340674A1 true PL340674A1 (en) 2001-02-12

Family

ID=7849618

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98340674A PL340674A1 (en) 1997-11-24 1998-11-11 Application of substituted aminomethyl chromanes in preventing degeneration of nerve cells and stimulating their regeneration

Country Status (30)

Country Link
US (2) US6235774B1 (https=)
EP (1) EP1051170B1 (https=)
JP (1) JP2001523716A (https=)
KR (1) KR20010032357A (https=)
CN (1) CN1134256C (https=)
AR (1) AR016973A1 (https=)
AT (1) ATE206615T1 (https=)
AU (1) AU745759B2 (https=)
BG (1) BG64167B1 (https=)
CA (1) CA2311126A1 (https=)
DE (2) DE19751949A1 (https=)
DK (1) DK1051170T3 (https=)
ES (1) ES2164465T3 (https=)
HN (1) HN1998000169A (https=)
HU (1) HUP0004369A3 (https=)
IL (1) IL135904A (https=)
IS (1) IS5496A (https=)
MY (1) MY118414A (https=)
NO (1) NO20002638L (https=)
NZ (1) NZ504656A (https=)
PE (1) PE134999A1 (https=)
PL (1) PL340674A1 (https=)
PT (1) PT1051170E (https=)
RU (1) RU2217140C2 (https=)
SI (1) SI1051170T1 (https=)
SV (1) SV1998000138A (https=)
TR (1) TR200001471T2 (https=)
TW (1) TW524690B (https=)
WO (1) WO1999026621A1 (https=)
ZA (1) ZA9810668B (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
UA73981C2 (en) * 2000-03-10 2005-10-17 Merck Patent Gmbh (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
BR0109193A (pt) * 2000-03-17 2003-05-27 Alcon Inc Compostos com atividade agonista 5-ht2 e 5-ht1a para tratamento do glaucoma
US20030207890A1 (en) 2001-02-23 2003-11-06 Collier Robert J Compounds with 5-ht1a activity useful for treating disorders of the outer retina
DE10058119A1 (de) * 2000-11-22 2002-05-23 Bayer Ag Pepinotan-Kit
SE0004455D0 (sv) * 2000-12-01 2000-12-01 Milos Pekny Method for neuron regeneration in the central nervous system
DE10101917A1 (de) * 2001-01-16 2002-07-18 Bayer Ag Verwendung von Chromanen
AU2002355170B2 (en) * 2001-07-26 2007-06-07 Merck Patent Gmbh Novel use of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane and its physiologically acceptable salts
BR0212199A (pt) * 2001-09-12 2004-10-05 Merck Patent Gmbh Uso de aminometil cromanos substituìdos no tratamento de distúrbios do movimento
DE10155075A1 (de) * 2001-11-09 2003-05-22 Merck Patent Gmbh Cyclische Sulfonamide
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
WO2005033092A1 (en) 2003-09-19 2005-04-14 Galileo Pharmaceuticals, Inc. Chroman derivatives
DE102004017627A1 (de) * 2004-04-10 2005-10-27 Bayer Healthcare Ag Verwendung von vollen 5-HT1A-Agonisten zur Hemmung der opiat/opioid-induzierten Atemdepression
UA125519C2 (uk) 2016-07-29 2022-04-13 Суновіон Фармасьютікалз Інк. Сполуки і композиції і їх застосування
CA3032141A1 (en) 2016-07-29 2018-02-01 Vadim ALEXANDROV Compounds and compositions and uses thereof
RU2651756C1 (ru) * 2017-05-10 2018-04-23 Федеральное государственное бюджетное образовательное учреждение Высшего Образования Кубанский Государственный Медицинский Университет Министерства Здравоохранения Российской Федерации, КубГМУ Препарат для предотвращения образования глиальных рубцов
BR112020001433A2 (pt) 2017-08-02 2020-07-28 Sunovion Pharmaceuticals Inc. compostos de isocromano e usos dos mesmos
MX2021010880A (es) 2019-03-14 2022-01-18 Sunovion Pharmaceuticals Inc Sales de un compuesto de isocromanilo y formas cristalinas, procesos de preparacion, usos terapeuticos y composiciones farmaceuticas de las mismas.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300523A (en) 1988-07-28 1994-04-05 Bayer Aktiengesellschaft Substituted aminomethyltetralins and their heterocyclic analogues
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
GB9012316D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE19522088A1 (de) 1995-06-19 1997-01-02 Bayer Ag Benzisothiazolyl-substituierte Aminomethylchromane
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration

Also Published As

Publication number Publication date
ZA9810668B (en) 1999-05-26
NO20002638D0 (no) 2000-05-23
WO1999026621A1 (de) 1999-06-03
BG104466A (en) 2001-02-28
HUP0004369A2 (hu) 2001-04-28
US20010018530A1 (en) 2001-08-30
SI1051170T1 (en) 2001-12-31
PE134999A1 (es) 2000-03-05
DK1051170T3 (da) 2001-12-27
MY118414A (en) 2004-10-30
AR016973A1 (es) 2001-08-01
BG64167B1 (bg) 2004-03-31
RU2217140C2 (ru) 2003-11-27
CN1279604A (zh) 2001-01-10
EP1051170A1 (de) 2000-11-15
EP1051170B1 (de) 2001-10-10
HN1998000169A (es) 1999-11-03
NZ504656A (en) 2002-02-01
TR200001471T2 (tr) 2000-10-23
AU745759B2 (en) 2002-03-28
US6235774B1 (en) 2001-05-22
ATE206615T1 (de) 2001-10-15
KR20010032357A (ko) 2001-04-16
IL135904A0 (en) 2001-05-20
TW524690B (en) 2003-03-21
JP2001523716A (ja) 2001-11-27
US6331561B2 (en) 2001-12-18
HUP0004369A3 (en) 2002-04-29
SV1998000138A (es) 1999-05-25
DE19751949A1 (de) 1999-05-27
AU1668599A (en) 1999-06-15
IS5496A (is) 2000-05-15
PT1051170E (pt) 2002-02-28
CN1134256C (zh) 2004-01-14
CA2311126A1 (en) 1999-06-03
IL135904A (en) 2003-07-06
NO20002638L (no) 2000-05-23
DE59801724D1 (de) 2001-11-15
ES2164465T3 (es) 2002-02-16

Similar Documents

Publication Publication Date Title
PL340674A1 (en) Application of substituted aminomethyl chromanes in preventing degeneration of nerve cells and stimulating their regeneration
PL335194A1 (en) Arylsulphonamides and their analogues as well as their application in treating neurodegenerative affections
GB2334444B (en) Hair treatment composition and method of manufacturing the composition
AU2653199A (en) Pseudospontaneous neural stimulation system and method
HUP0103114A3 (en) Apolipoprotein a-1 agonists and their use to treat dyslipidemic disorders
HU9801634D0 (en) Genetically modified cells and their use in prevention or therapy of disease
PL340604A1 (en) Application of macrolydes in treating tumours and maculopathy
HUP9801511A3 (en) Human semaphorin-l (h-sema-l) and corresponding semaphorine in other species
IL118119A0 (en) Azacycloalkane derivatives their preparation and their application in therapy
AU1996599A (en) Long-term survival and regeneration of central nervous system neurons
AU6242498A (en) Methods for treating central and peripheral nerve pain
PL332313A1 (en) Application of benzopyranoles in treatment of neurological disorders
AU6925598A (en) Composition and method for stimulating pollen germination
ZA983740B (en) Novel amidine derivatives and their use in therapy
ID25880A (id) Turunan-turunan amonium bis-kuartener sebagai obat pengurang ketegangan pada saraf/otot
ZA982579B (en) Method of stimulating nerve regeneration
PL338123A1 (en) 6-pyrrolydin-2-ylpyridines, their production and application in therapy
EP1009433A4 (en) THERAPEUTIC COMPOSITION AND TREATMENT METHOD
AU6014698A (en) Filter aid protein-polysaccharide complex composition and method of use
GB9721075D0 (en) Materials and methods relating to the stimulation of cells
AU8379798A (en) Skin aging and wound treatment using cell migration agents
PL337665A1 (en) (s) 2-methylamine-2-phenyl-n-butyl-3,4,5-trimethoxybezoate and application thereof in treating long-lasting pains
GB9605515D0 (en) Improvements in or relating to cell stimulation
IL118120A0 (en) Methods of preventing neuron degeneration and promoting neuron regeneration
AU5871898A (en) Microparticles and their use in cancer treatment