PA8684801A1 - DERIVADOS DE PIRIDO[2,3-d]PIRIMIDINA, SU PREPARACION, SU APLICACION EN TERAPIA - Google Patents

DERIVADOS DE PIRIDO[2,3-d]PIRIMIDINA, SU PREPARACION, SU APLICACION EN TERAPIA

Info

Publication number
PA8684801A1
PA8684801A1 PA20068684801A PA8684801A PA8684801A1 PA 8684801 A1 PA8684801 A1 PA 8684801A1 PA 20068684801 A PA20068684801 A PA 20068684801A PA 8684801 A PA8684801 A PA 8684801A PA 8684801 A1 PA8684801 A1 PA 8684801A1
Authority
PA
Panama
Prior art keywords
pirido
preparation
pirimidine
therapy
derivatives
Prior art date
Application number
PA20068684801A
Other languages
English (en)
Spanish (es)
Inventor
Pierre Casellas
Samir Jegham
Bernard Bourrie
Claude Muneaux
Pierre Perreaut
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of PA8684801A1 publication Critical patent/PA8684801A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PA20068684801A 2005-07-01 2006-06-30 DERIVADOS DE PIRIDO[2,3-d]PIRIMIDINA, SU PREPARACION, SU APLICACION EN TERAPIA PA8684801A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0507032A FR2887882B1 (fr) 2005-07-01 2005-07-01 Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique

Publications (1)

Publication Number Publication Date
PA8684801A1 true PA8684801A1 (es) 2007-01-17

Family

ID=36096420

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20068684801A PA8684801A1 (es) 2005-07-01 2006-06-30 DERIVADOS DE PIRIDO[2,3-d]PIRIMIDINA, SU PREPARACION, SU APLICACION EN TERAPIA

Country Status (40)

Country Link
US (2) US7504406B2 (enExample)
EP (2) EP2020410B1 (enExample)
JP (1) JP4472009B2 (enExample)
KR (1) KR101298344B1 (enExample)
CN (2) CN101213196B (enExample)
AR (1) AR054812A1 (enExample)
AT (1) ATE423119T1 (enExample)
AU (1) AU2006264801B2 (enExample)
BR (1) BRPI0613020A2 (enExample)
CA (1) CA2610794C (enExample)
CR (1) CR9568A (enExample)
CY (2) CY1110457T1 (enExample)
DE (1) DE602006005246D1 (enExample)
DK (2) DK2020410T3 (enExample)
DO (1) DOP2006000145A (enExample)
EA (1) EA014312B1 (enExample)
EC (1) ECSP078011A (enExample)
ES (2) ES2450067T3 (enExample)
FR (1) FR2887882B1 (enExample)
HR (2) HRP20090236T1 (enExample)
IL (1) IL187900A0 (enExample)
JO (1) JO2550B1 (enExample)
MA (1) MA29561B1 (enExample)
ME (1) ME01813B (enExample)
MX (1) MX2007016239A (enExample)
MY (1) MY143089A (enExample)
NO (1) NO20080418L (enExample)
NZ (1) NZ564072A (enExample)
PA (1) PA8684801A1 (enExample)
PE (1) PE20070139A1 (enExample)
PL (2) PL1902054T3 (enExample)
PT (2) PT1902054E (enExample)
RS (2) RS53211B (enExample)
SI (2) SI2020410T1 (enExample)
TN (1) TNSN07440A1 (enExample)
TW (1) TWI321566B (enExample)
UA (1) UA92021C2 (enExample)
UY (1) UY29645A1 (enExample)
WO (1) WO2007003765A1 (enExample)
ZA (1) ZA200711032B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2873118B1 (fr) 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
FR2887882B1 (fr) * 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
FR2896246B1 (fr) 2006-01-13 2008-08-15 Sanofi Aventis Sa Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
FR2910813B1 (fr) * 2006-12-28 2009-02-06 Sanofi Aventis Sa Nouvelle utilisation therapeutique pour le traitement des leucemies
EP2344484B1 (en) * 2008-10-17 2016-06-08 Akaal Pharma Pty Ltd S1p receptors modulators and use thereof
AU2009304596A1 (en) 2008-10-17 2010-04-22 Akaal Pharma Pty Ltd S1P receptors modulators
FR2948568B1 (fr) 2009-07-30 2012-08-24 Sanofi Aventis Formulation pharmaceutique
CN103204825B (zh) * 2012-01-17 2015-03-04 上海科州药物研发有限公司 作为蛋白激酶抑制剂的苯并噻唑化合物及其制备方法和用途
EP2638911A1 (en) 2012-03-14 2013-09-18 Sanofi Novel combinations for treating acute myeloid leukaemia or chronic myeloid leukaemia
CN103833771A (zh) * 2012-11-22 2014-06-04 天津滨江药物研发有限公司 作为蛋白激酶Mek抑制剂的苯并五元杂环化合物及其制备方法和用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1171218A (en) * 1967-11-09 1969-11-19 Parke Davis & Co New Heterocyclic Amine Compounds and Methods for their Production
JPH04128276A (ja) 1990-09-19 1992-04-28 Pfizer Pharmaceut Co Ltd アミノベンゾサルタム誘導体およびその用途
PT790997E (pt) * 1994-11-14 2000-06-30 Warner Lambert Co 6-aril pirido¬2,3-d|pirimidinas e naftiridinas para inibir a proliferacao celular mediada pela quinase da tirosina proteica
IL115256A0 (en) 1994-11-14 1995-12-31 Warner Lambert Co 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use
US5620981A (en) * 1995-05-03 1997-04-15 Warner-Lambert Company Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation
IL117923A (en) 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
PL356802A1 (en) * 2000-01-25 2004-07-12 Warner-Lambert Company Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors
EP1268476A1 (en) * 2000-03-06 2003-01-02 Warner-Lambert Company 5-alkylpyrido[2,3-d]pyrimidines tyrosine kinase inhibitors
AU2001277032A1 (en) 2000-08-04 2002-02-18 Warner Lambert Company 2-(4-pyridyl)amino-6-dialkoxyphenyl-pyrido(2,3-d)pyrimidin-7 ones
US20030105115A1 (en) * 2001-06-21 2003-06-05 Metcalf Chester A. Novel pyridopyrimidines and uses thereof
AU2002952453A0 (en) * 2002-11-01 2002-11-21 Novogen Research Pty Ltd Aminated isoflavonoid derivatives and uses thereof
US20050009849A1 (en) 2003-01-03 2005-01-13 Veach Darren R. Pyridopyrimidine kinase inhibitors
TW200502236A (en) * 2003-03-28 2005-01-16 Hoffmann La Roche Novel pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents
WO2005105097A2 (en) 2004-04-28 2005-11-10 Gpc Biotech Ag Pyridopyrimidines for treating inflammatory and other diseases
FR2873118B1 (fr) * 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
FR2887882B1 (fr) * 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
FR2896246B1 (fr) 2006-01-13 2008-08-15 Sanofi Aventis Sa Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
US8338435B2 (en) * 2006-07-20 2012-12-25 Gilead Sciences, Inc. Substituted pyrido(3,2-D) pyrimidines and pharmaceutical compositions for treating viral infections

Also Published As

Publication number Publication date
DOP2006000145A (es) 2008-01-31
JO2550B1 (en) 2010-09-05
EP2020410B1 (fr) 2013-12-18
SI1902054T1 (sl) 2009-06-30
HRP20140246T1 (hr) 2014-06-20
CN102260258A (zh) 2011-11-30
EP2020410A1 (fr) 2009-02-04
US8008310B2 (en) 2011-08-30
ME01813B (me) 2014-09-20
CN101213196A (zh) 2008-07-02
EA014312B1 (ru) 2010-10-29
ZA200711032B (en) 2009-04-29
JP4472009B2 (ja) 2010-06-02
PT2020410E (pt) 2014-03-20
AU2006264801B2 (en) 2012-05-10
NZ564072A (en) 2012-02-24
FR2887882A1 (fr) 2007-01-05
DK1902054T3 (da) 2009-06-15
MX2007016239A (es) 2008-03-06
CR9568A (es) 2008-02-20
HRP20090236T1 (hr) 2009-05-31
TW200745102A (en) 2007-12-16
PT1902054E (pt) 2009-04-22
NO20080418L (no) 2008-03-28
RS53211B (sr) 2014-08-29
RS50781B (sr) 2010-08-31
CA2610794C (fr) 2012-02-21
EP1902054B1 (fr) 2009-02-18
US7504406B2 (en) 2009-03-17
FR2887882B1 (fr) 2007-09-07
EA200800223A1 (ru) 2008-06-30
MY143089A (en) 2011-03-15
US20090163522A1 (en) 2009-06-25
TWI321566B (en) 2010-03-11
PL2020410T3 (pl) 2014-05-30
EP1902054A1 (fr) 2008-03-26
AU2006264801A1 (en) 2007-01-11
CA2610794A1 (fr) 2007-01-11
BRPI0613020A2 (pt) 2010-12-14
CY1110457T1 (el) 2015-04-29
DE602006005246D1 (de) 2009-04-02
KR20080021714A (ko) 2008-03-07
PL1902054T3 (pl) 2009-07-31
DK2020410T3 (en) 2014-03-24
ATE423119T1 (de) 2009-03-15
PE20070139A1 (es) 2007-03-07
SI2020410T1 (sl) 2014-04-30
UY29645A1 (es) 2007-01-31
KR101298344B1 (ko) 2013-08-20
TNSN07440A1 (en) 2009-03-17
CN102260258B (zh) 2015-01-07
US20080176874A1 (en) 2008-07-24
JP2008544975A (ja) 2008-12-11
UA92021C2 (ru) 2010-09-27
CN101213196B (zh) 2011-09-07
ES2322101T3 (es) 2009-06-16
ECSP078011A (es) 2008-01-23
MA29561B1 (fr) 2008-06-02
ES2450067T3 (es) 2014-03-21
CY1114989T1 (el) 2016-12-14
AR054812A1 (es) 2007-07-18
HK1122797A1 (en) 2009-05-29
WO2007003765A1 (fr) 2007-01-11
IL187900A0 (en) 2008-03-20

Similar Documents

Publication Publication Date Title
CR9568A (es) DERIVADOS DE PIRIDO[2,3-d]PIRIMIDINA, SU PREPARACION, SU APLICACION EN TERAPEUTICA
CY1120257T1 (el) ΠΥΡΡΟΛΟ[2,3b]ΠΥΡΙΔΙΝ-4-ΥΛΑΜΙΝΕΣ ΚΑΙ ΠΥΡΡΟΛΟ[2,3b]ΠΥΡΙΜΙΔΙΝ-4-ΥΛΑΜΙΝΕΣ ΩΣ ΑΝΑΣΤΟΛΕΙΣ ΚΙΝΑΣΩΝ JANUS
CY1118607T1 (el) ΕΤΕΡΟΑΡΥΛΟ ΥΠΟΚΑΤΕΣΤΗΜΕΝΕΣ ΠΥΡΡΟΛΟ[2,3-b]ΠΥΡΙΔΙΝΕΣ ΚΑΙ ΠΥΡΡΟΛΟ [2,3-b]ΠΥΡΙΜΙΔΙΝΕΣ ΩΣ ΑΝΑΣΤΟΛΕΙΣ ΚΙΝΑΣΗΣ JANUS
CY1115188T1 (el) Πολυκυκλικες ετεροαρυλ-υποκατεστημενες τριαζολες χρησιμες ως αναστολεις του axl
CY1117743T1 (el) Διυποκατεστημενα οκταϋδροπυρρολο [3,4-c]πυρρολια ως ρυθμιστες υποδοχεα ορεξινης
DK1893196T3 (da) Diarylhydantoin-forbindelse
EP1844077A4 (en) DR5 ANTIBODIES AND THEIR USE
UY30892A1 (es) Inhibidores de la actividad akt
CY1113642T1 (el) Γεφυρωμενες δικυκλικες ετεροαρυλ υποκατεστημενες τριαζολες, χρησιμες ως αναστολεις της axl
BRPI0821151A2 (pt) Derivados de pirazol e uso dos mesmos como inibidores de quinases dependentes de ciclina
DOP2010000304A (es) Composiciones y metodos de preparacion y uso de las mismas
BRPI0814529A2 (pt) Derivados de 2-3-dihidrobenzo[1,4]dioxin-2-ilmetil como antagonistas alfa2c para o uso no tratamento de doenças do sistema nervoso periférico e central.
BR0318383A (pt) derivados de pirazoloisoquinolina como inibidores de cinase
MX2010000098A (es) Derivados de guanina policiclicos y sus metodos de uso.
SV2006002283A (es) Formulaciones
MXPA05008478A (es) Heterociclos sustituidos.
CL2011000119A1 (es) Compuestos derivados de triazolo[4,3-a]piridina; procedimiento de preparacion; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer.
CR11259A (es) Bromhidrato de bupropion y aplicaciones terapueticas
BRPI0514721A (pt) uso de compostos de peptìdeos para tratar dor de cáncer ósseo, dor induzida por quimioterapia e nucleosìdeo
BRPI0614397A2 (pt) compostos de pirimidina como moduladores de receptor de serotonina
CO5660287A2 (es) Derivados de tetrahidrocarbazol y su uso farmaceutico
UY29036A1 (es) Derivados de oxopiperidina, su preparacion y su aplicacion en terapeutica
EA201070195A1 (ru) ПРОИЗВОДНЫЕ 1,2,3,4-ТЕТРАГИДРОПИРРОЛО [1,2-А]ПИРАЗИН-6-КАРБОКСАМИДОВ И 2,3,4,5-ТЕТРАГИДРОПИРРОЛО [1,2-a][1,4]-ДИАЗЕПИН-7-КАРБОКСАМИДОВ, ИХ ПОЛУЧЕНИЕ И ИХ ПРИМЕНЕНИЕ В ТЕРАПИИ
UY28345A1 (es) Compuestos novedosos
EA200971067A1 (ru) Триазолиламинопиримидиновые соединения